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   1 l outcomes, such as exercise intolerance and premature mortality.                                    
     2 creased rates of violent crime, suicide, and premature mortality.                                    
     3 onviction of a violent offence, suicide, and premature mortality.                                    
     4 ia constitute risk factors for morbidity and premature mortality.                                    
     5  increased risk for subsequent morbidity and premature mortality.                                    
     6  epilepsy (n=69,995) for risks and causes of premature mortality.                                    
     7  including diabetes-associated morbidity and premature mortality.                                    
     8 izure-related deaths contribute to excessive premature mortality.                                    
     9 ssociation between acute HHV-8 infection and premature mortality.                                    
    10 e muscle wasting, or muscular dystrophy, and premature mortality.                                    
    11 reduced hypersynchrony, memory deficits, and premature mortality.                                    
    12 tudy of people with epilepsy with regards to premature mortality.                                    
    13 e the reasons for this long-term increase in premature mortality.                                    
    14  control, increasing morbidity, and risk for premature mortality.                                    
    15 opathy in mice, leading to heart failure and premature mortality.                                    
    16 rning and memory, behavioral alterations and premature mortality.                                    
    17 tional decline and comorbidities, leading to premature mortality.                                    
    18         Hepatitis C is an important cause of premature mortality.                                    
    19 one (O(3)), an air pollutant associated with premature mortality.                                    
    20 rsons with schizophrenia have a high risk of premature mortality.                                    
    21 ements may be at slightly increased risk for premature mortality.                                    
    22 prevent excess age-associated DNA damage and premature mortality.                                    
    23 vascular disease, retinopathy, dementia, and premature mortality.                                    
    24 isplayed focused abnormalities, resulting in premature mortality.                                    
    25 he development of overt heart failure, and a premature mortality.                                    
    26 cardiac enlargement, growth retardation, and premature mortality.                                    
    27 ictor of the obesity-related morbidities and premature mortality.                                    
    28 aracteristic of older TG mice, and abolished premature mortality.                                    
    29 erable economic losses, work disability, and premature mortality.                                    
    30 ventricular failure, cardiac dilatation, and premature mortality.                                    
    31 ople with diabetes and its presence predicts premature mortality.                                    
    32 may lead to substantial comorbid disease and premature mortality.                                    
    33  peripheral edema, intracardiac thrombi, and premature mortality.                                    
    34 ically active and thereby reduce the risk of premature mortality.                                    
    35  health conditions exceeds 40%, resulting in premature mortality.                                    
    36 slightly in 2015, possibly because of rising premature mortality.                                    
    37 al connection qualifies as a risk factor for premature mortality.                                    
    38 mple, which could increase the likelihood of premature mortality.                                    
    39 an air pollution responsible for substantial premature mortality.                                    
    40 sk for cardiovascular disease, diabetes, and premature mortality.                                    
    41  organ damage, impaired quality of life, and premature mortality.                                    
    42 ed in the etiologies of chronic diseases and premature mortality.                                    
    43 ent frequency is a potential risk factor for premature mortality.                                    
    44 mately 5% for disability pension, and 2% for premature mortality.                                    
    45 inactivity is a leading cause of obesity and premature mortality.                                    
    46 ed by known determinants or risk factors for premature mortality.                                    
    47          Opioid dependence increases risk of premature mortality.                                    
    48 the causes of ill health as well as those of premature mortality.                                    
    49  causally linked to cardiovascular events or premature mortality.                                    
    50 ) is a leading environmental risk factor for premature mortality.                                    
    51 ic disorders lead to age-related disease and premature mortality.                                    
    52 Disability and Years of Life Lost because of premature mortality.                                    
    53  air pollution is the leading contributor to premature mortality [~ 650 annual deaths; 95% confidence
  
    55 0) years with substantially elevated odds of premature mortality (adjusted odds ratio [aOR] of 11.1 [
  
    57     Frailty is associated with morbidity and premature mortality among elderly HIV-uninfected adults,
    58 p in the development of strategies to reduce premature mortality among patients with chronic kidney d
    59 ssion is associated with clinical events and premature mortality among patients with established coro
    60  primary medical care may effectively reduce premature mortality among persons with bipolar disorder.
  
    62 rne particulate pollution is associated with premature mortality and a range of inflammatory illnesse
  
    64 iated with adverse health effects, including premature mortality and cardiopulmonary and respiratory 
    65 tates such as depression are associated with premature mortality and increased risk of coronary heart
    66  functions for chronic exposure to PM2.5 and premature mortality and its major sources of uncertainty
  
  
  
    70 w that elevating klotho expression decreases premature mortality and network dysfunction in human amy
    71 mistry model to investigate the link between premature mortality and seven emission source categories
    72 Personality disorder is also associated with premature mortality and suicide, and needs to be identif
    73  in Alzheimer's disease brains and modulates premature mortality and synaptotoxicity in hAPP mice.   
    74 quires a composite metric that captures both premature mortality and the prevalence and severity of i
    75 amic diameter; PM(2.5)), are associated with premature mortality and they disrupt global and regional
    76 d chronic diseases, suicide, other causes of premature mortality and violence, and counteracting the 
    77  WT are at a substantially increased risk of premature mortality, and 75% of excess deaths were accou
    78 olicies on smoking prevalence and associated premature mortality, and the effect that additional poli
  
    80  injury have a large effect on morbidity and premature mortality, and typically accelerate in the sec
    81 ions of social isolation and loneliness with premature mortality are well known, but the risk factors
    82 I: 1.7-1.8; 4,691 versus 29,778 events), and premature mortality (aRR = 1.7; 95% CI: 1.6-1.9; 799 ver
  
  
    85 ribe global trends and regional variation in premature mortality attributable to CVD, (2) review past
  
    87  study, we aimed to estimate health impacts (premature mortalities) attributable to PM2.5 and O3 from
    88  recipients have a greatly increased risk of premature mortality because of cardiovascular disease an
    89 experience debilitating neuropathic pain and premature mortality because of renal failure, cardiovasc
    90 s and psychiatric inpatient hospitalisation, premature mortality (before age 41 y), low educational a
    91 ated with an increased risk of morbidity and premature mortality, but it is not known if the same is 
    92  is associated with blunted CD4 recovery and premature mortality, but its causes remain incompletely 
  
    94    Epilepsy is associated with high rates of premature mortality, but the contribution of psychiatric
  
  
    97 sed with psoriasis have an increased risk of premature mortality, but the underlying reasons for this
    98 e time physical activity reduces the risk of premature mortality, but the years of life expectancy ga
    99 njuries in Mexico, making a 40% reduction in premature mortality by 2030 feasible and putting Mexico 
  
  
  
   103 re we combine four global models to estimate premature mortality caused by fine particulate matter (P
   104 ubstantially protected the AD-like mice from premature mortality, cerebral plaque formation, increase
   105 of childhood cancer are at increased risk of premature mortality compared with the general population
   106 ardiac function, dilated cardiomyopathy, and premature mortality, consistent with heart failure.     
  
   108 s and define an exposure-based metric as the premature mortality count related to short-term ozone ex
  
  
   111 b(-/-) mice exhibited decreased body weight, premature mortality, decreased female fertility, and del
  
   113  can cause adverse health effects, including premature mortality due to cardiopulmonary diseases and 
  
   115 he UN Sustainable Development Goal to reduce premature mortality due to CVRDs by a third by 2030 will
   116 ilepsy have greatly increased probability of premature mortality due to sudden unexpected death in ep
  
   118 n Indians and Alaska Natives had the highest premature mortality, followed by black individuals.     
  
   120 st scalable strategies to reduce the risk of premature mortality from atherosclerosis by 25% by 2025 
   121 vel, resource-efficient strategies to reduce premature mortality from CVD, including (1) effective me
  
   123      We assessed the prevalence and risks of premature mortality from external causes such as suicide
   124  mortality rates underestimated the elevated premature mortality from infections (SMR 22-693) and kid
   125  a global target of reducing tobacco use and premature mortality from non-communicable diseases by a 
   126 alth policy goals include a 25% reduction in premature mortality from noncommunicable diseases by 202
  
   128   If the agreed risk factor targets are met, premature mortality from the four main NCDs will decreas
  
  
   131  India and China, have the largest impact on premature mortality globally, being even more dominant i
  
  
   134 as been associated with higher suicide risk, premature mortality, homelessness, violent crime and inc
   135 enarios were then constructed reflecting CVD premature mortality if United Nations risk factor target
   136 mbryonic Klf4 deletion resulted in postnatal premature mortality, impaired mitochondrial biogenesis, 
  
  
  
  
   141 epilepsy (SUDEP) is the most common cause of premature mortality in epilepsy and was linked to mutati
   142  (CVD) is the leading cause of morbidity and premature mortality in Europe and the United States, and
  
   144 ing cessation, have contributed to declining premature mortality in Hispanic individuals, black indiv
   145 tic marker of disease risk, progression, and premature mortality in many types of cancer, including b
   146 IDS) versus other leading causes of death on premature mortality in New York City, New York, between 
  
   148 s remain the leading causes of morbidity and premature mortality in patients with diabetes mellitus. 
   149  stroke and myocardial infarction, result in premature mortality in patients with Fabry disease, an X
   150     Four retrospective studies have reported premature mortality in patients with hypopituitarism wit
   151 emphasized their major role as predictors of premature mortality in patients with rheumatoid arthriti
  
  
  
   155 e is the leading preventable risk factor for premature mortality in the Chinese general population.  
  
  
   158 l aortic valve disease are a major source of premature mortality in TS, but accurate data on the prev
  
  
   161 oor physical function may be associated with premature mortality, injurious falls, bone fracture, and
  
  
  
  
  
   167 hich contribute to significant morbidity and premature mortality, it is timely to review the role of 
   168 patic steatosis, dilated cardiomyopathy, and premature mortality observed in mice lacking Phd2 alone 
  
   170 ept method to quantify the effects on global premature mortality of changes to PM2.5 precursor emissi
  
  
   173  processes, which cumulatively contribute to premature mortality on a scale rivaling that of smoking.
  
   175     Inactivity causes 9% (range 5.1-12.5) of premature mortality, or more than 5.3 million of the 57 
   176 ociated with substantially elevated risks of premature mortality, particularly for suicide, injuries,
  
  
  
  
   181 ong-term exposure to PM2.5 and PM2.5-related premature mortality (PM2.5-mortality) and its response t
  
  
  
   185 (VEGF) concentrations (P <.0005), as well as premature mortality related to cerebral vascular events 
  
   187 d individuals, yet substantial morbidity and premature mortality remain associated with this disorder
  
   189 fried potatoes) is associated with increased premature mortality risk in a North American cohort.A lo
  
  
   192 renia have a significantly increased risk of premature mortality, sample size limitations of previous
  
  
   195 have significantly worse health outcomes and premature mortality than the general population, owing t
  
   197 or for cardiovascular and kidney disease and premature mortality that is improved by the DASH (Dietar
   198 ough delinquency is strongly associated with premature mortality, the etiological links remain unclea
  
   200  epidemiological cohort studies that connect premature mortality to a wide range of causes, including
   201 ulated sensitivities of global PM2.5-related premature mortality to emissions of precursor gases (SO2
  
   203 susceptibility of mice to hAPP/Abeta-induced premature mortality was decreased by Fyn ablation and in
  
   205 hat the effect of NO2 from road traffic upon premature mortality was ten-fold greater than that of PM
  
  
   208 onviction of a violent offence, suicide, and premature mortality, with follow-up until conviction of 
   209 ately 670 cardiovascular and 300 respiratory premature mortalities within North America could be attr
  
  
   212  leading causes of years of life lost due to premature mortality (YLLs) in 2010, similar to what was 
  
   214 disability (YLDs), years of life lost due to premature mortality (YLLs), and life expectancy by age a
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