ライフサイエンスコーパス: premeiotic

1 omatic pairing is qualitatively analogous to premeiotic and early meiotic pairing.

2 normalized cDNA library was constructed from premeiotic and meiotic floral buds and sequenced to gene

3 on lysine 56 (H3K56) occurs both during the premeiotic and mitotic S phase and persists throughout D

4 The same origins are used during premeiotic and mitotic S-phases.

5 acute irradiation with x-rays was studied at premeiotic and postmeiotic stages of spermatogenesis.

6 As a result, in most am1 mutants premeiotic cells enter mitosis instead of meiosis.

7 evidence that ENU induces point mutations in premeiotic cells, the range of mutations induced in post

8 ions induced by treatment of spermatogonial (premeiotic) cells with the chemical mutagen N-ethyl-N-ni

9 These events occur without premeiotic chromosomal replication, sister chromatid coh

10 Phl does not regulate chromosome pairing by premeiotic chromosome alignment and a mitotic spindle-ce

11 We report that the occurrence of these early premeiotic clusters of new identical mutant alleles incr

12 es during meiosis requires a single round of premeiotic DNA replication (meiS) followed by two succes

13 onclude that CLB5 and CLB6 are essential for premeiotic DNA replication and, consequently, for activa

14 ryogamy is not supposed to occur until after premeiotic DNA replication in Pyrenomycetous fungi such

15 h as nicks and gaps, which accumulate during premeiotic DNA replication in the absence of Okazaki fra

16 ned a rad9-1;msh5-22 double mutant, in which premeiotic DNA replication is inhibited.

17 rs in C. cinereus spo11 and rad50 mutants if premeiotic DNA replication is prevented.

18 as crucial meiotic functions: it facilitates premeiotic DNA replication, and it is essential for the

19 After completing premeiotic DNA replication, commitment to meiotic recomb

20 normal, but these cells then fail to undergo premeiotic DNA replication, meiotic chromosome condensat

21 commences at a regulatory point upstream of premeiotic DNA replication.

22 recombination is mechanistically coupled to premeiotic DNA replication.

23 ther mutant, spo22-1, which does not undergo premeiotic DNA replication.

24 inent DNA breaks that appeared shortly after premeiotic DNA replication.

25 clb5 clb6/clb6 mutants are unable to perform premeiotic DNA replication.

26 elopment, as they show substantial delays in premeiotic DNA synthesis and defects in the expression o

27 ells at an early stage of sporulation before premeiotic DNA synthesis and induction of meiotic-specif

28 he restrictive temperature without affecting premeiotic DNA synthesis and recombination.

29 ids are reduced in their ability to complete premeiotic DNA synthesis and the meiotic divisions, and

30 n preleptotene spermatocytes, cells in which premeiotic DNA synthesis occurs.

31 Premeiotic DNA synthesis was undetectable in glc7 mutant

32 otic recombination, and Rem1 is required for premeiotic DNA synthesis when Cig2 is not present.

33 mutant, mum2 deletion strains do not undergo premeiotic DNA synthesis, arrest prior to the first meio

34 ary phase or enter into either premitotic or premeiotic DNA synthesis.

35 iocytes through the stochastic occurrence of premeiotic endomitosis.

36 d meiocytes through the ectopic induction of premeiotic endomitosis.

37 a, a single diploid cell is specified as the premeiotic female gamete precursor.

38 hese genes may play other roles, including a premeiotic function.

39 lly, our phylogenetic analyses indicate that premeiotic functions of planarian boule2 and vertebrate

40 e invertebrate model system for studying the premeiotic functions of the DAZ protein family.

41 ome behavior and centriole engagement during premeiotic G2 arrest of Drosophila male meiosis.

42 Regulation of cell cycle arrest in premeiotic G2 phase coordinates germ cell maturation and

43 phorylation of Cdk1 by Myt1 kinase regulates premeiotic G2 phase of Drosophila male meiosis.

44 ophytic phase relies on the specification of premeiotic gamete precursors from sporophytic cells in t

45 legans, promote a form of homology-dependent premeiotic gene conversion upon excision.

46 products of repeat-induced point mutation, a premeiotic genome defense system that litters duplicated

47 ylation of dispersed repeated sequences in a premeiotic genome scanning process that occurs in male g

48 enerate hundreds of oocytes, despite a small premeiotic germ cell pool.

49 nction with high-level expression of Sbf1 in premeiotic germ cells and Sertoli's cells is consistent

50 ction can increase the relative frequency of premeiotic germ cells carrying such mutations, although

51 The premeiotic germ cells of Drosophila provide a useful mod

52 ion of MOTs suggesting an origin either from premeiotic germ cells or from a somatic cell line.

53 erformed targeted and reversible ablation of premeiotic germ cells undergoing differentiation into oo

54 This is in contrast to premeiotic germ cells which were found to express little

55 in the repair of double-strand breaks in the premeiotic germ line of Drosophila males.

56 ired for maintaining the ploidy level of the premeiotic germ lineage and that subtle defects in cytok

57 gene pool together due to replication from a premeiotic germline mutation and distribution to multipl

58 meres revealed that, as cells passed through premeiotic interphase and into leptotene, there was an i

59 y was also assessed in nuclear extracts from premeiotic, meiotic, and postmeiotic spermatogenic cell

60 spontaneous mutation subsequent to the last premeiotic mitosis and before the first postmeiotic one

61 ndividuals, indicating that there had been a premeiotic mutation cluster, although surprisingly one i

62 e family can share the same mutations due to premeiotic mutation events, so that the number of mutant

63 re prevalent than those carrying products of premeiotic or meiotic breakage or rearrangements, (b) th

64 that OdsH abundance and localization in the premeiotic phases of spermatogenesis differ between spec

65 pendent spatiotemporal regulation with 21-nt premeiotic phasiRNAs dependent on epidermal and 24-nt me

66 The cellular proteins expressed in premeiotic primary spermatocytes from Tsr mutant and wil

67 ecific-locus mutations at a higher rate than premeiotic regimens, suggesting that postmeiotic mutagen

68 cally identical products of the first of two premeiotic replication cycles.

69 equirement for these proteins imposed by the premeiotic replication process itself or a requirement f

70 myces pombe are recruited around the time of premeiotic replication, and Rec10, a component of meiosi

71 -dependent breaks, they appear early, during premeiotic replication.

72 Our study uncovers a premeiotic role for an invertebrate boule homolog and of

73 Dazl is believed to have acquired its premeiotic role in a vertebrate ancestor following the d

74 This suggests that they happen before the premeiotic round of DNA synthesis.

75 Coordination between premeiotic S and DSB formation may be achieved by using

76 tor (CKI) Dacapo (Dap) as a key regulator of premeiotic S phase and genomic stability during Drosophi

77 we show that H3 K56ac is also present during premeiotic S phase and is conserved in fission yeast.

78 microtubule-kinetochore interactions during premeiotic S phase and prophase I is central to establis

79 microtubule-kinetochore interactions during premeiotic S phase and prophase I is essential for estab

80 ences during the meiotic cell cycle: one for premeiotic S phase and the other for initiating recombin

81 licensing of DNA replication origins for the premeiotic S phase by restricting Cdk activity in the ea

82 e-wide changes in the replication program of premeiotic S phase do not affect meiotic progression, in

83 The proper execution of premeiotic S phase is essential to both the maintenance

84 However, the regulation of premeiotic S phase remains poorly defined in metazoa.

85 We propose that chk-2 functions during premeiotic S phase to enable chromosomes to become compe

86 fied from the mitotic cell cycle by having a premeiotic S phase which leads to high levels of recombi

87 tant that did not form spores arrested after premeiotic S phase with a single undivided nucleus and l

88 with a subset of chromatin sites as early as premeiotic S phase, hours before either the appearance o

89 aks (DSBs), which appear after completion of premeiotic S phase, leading to the view that initiation

90 gh all 16 cells initiate meiosis and undergo premeiotic S phase, only the oocyte retains its meiotic

91 sporulation medium, cells undergo a delayed premeiotic S phase, then arrest in prophase before doubl

92 ctivity and accumulate DNA damage during the premeiotic S phase.

93 and in G(2) if cells are already undergoing premeiotic S phase.

94 4p) and Orp1p (Orc1p), are also required for premeiotic S phase.

95 d Rad50 in SC formation partially depends on premeiotic S phase.

96 ut a screen for mutants that arrest prior to premeiotic S phase.

97 GC differentiation; (iii) RA synthesized by premeiotic spermatocytes cell autonomously induces meiot

98 In premeiotic spermatocytes it localizes to all four centri

99 e, is highly expressed in ovarian cancer and premeiotic spermatocytes with relatively little expressi

100 mutation rate was found after irradiation of premeiotic spermatogonia and stem cells, whereas the fre

101 wn to be germ-cell-specific and expressed in premeiotic spermatogonia, plus another 21 germ-cell-spec

102 ogenic arrest predominately at the diplotene premeiotic stage and almost no sperm detected in the epi

103 arly-diverging lineage and could represent a premeiotic stage in eukaryotic evolution.

104 c rearrangement of telomere locations during premeiotic stages in fission yeast.

105 19F) males are sterile due to a block at the premeiotic stages in spermatogenesis.

106 ponse curve for paternal mutation induced at premeiotic stages was found, with a doubling dose of 0.3

107 NA library produced from mRNA extracted from premeiotic tomato flowers (Lycopersicon esculentum).

108 We conclude that the premeiotic transitions are coordinated by RA from Sertol

109 Two premeiotic transitions, spermatogonial differentiation a

110 postmeiotic transitions, but not for the two premeiotic transitions.