ライフサイエンスコーパス: preproenkephalin

1 s used to measure changes in mRNA levels for preproenkephalin A (ENK), D1 dopamine receptor, protachy

2 nic nicotine treatment and its withdrawal on preproenkephalin A mRNA levels (PPE mRNA) in specific ra

3 ide I(1-10) (SPQLEDEAKE), a novel product of preproenkephalin A processing, using MS2, MS3, and datab

4 transcription after hypovolemia, but not the preproenkephalin and c-fos mRNA responses or ACTH secret

5 subregion-specific upregulation of striatal preproenkephalin and prodynorhin gene expression in the

6 tal NGFI-B mRNA colocalized with a subset of preproenkephalin and prodynorphin positive spiny neurons

7 rmone, galanin, neuropeptide Y, neurotensin, preproenkephalin and tachykinin 1; this involved a criti

8 n bind to the promoter the hypothalamic gene preproenkephalin and that interations between liganded T

9 ons) fire in-phase with STN neurons, express preproenkephalin, and only innervate the striatum.

10 Hence, preproenkephalin cDNA delivery selectively blocked hyper

11 on-defective herpes virus carrying the human preproenkephalin cDNA was injected bilaterally into the

12 ontaining virus) and of human proenkephalin (preproenkephalin-encoding virus) in the central terminal

13 hat OBX leads to increased expression of the preproenkephalin (ENK) gene in the olfactory tubercle (O

14 mine depletion and the maintenance of normal preproenkephalin expression.

15 The mRNA level of preproenkephalin in the rostral ventrolateral medulla (r

16 ned whether ovariectomized female transgenic preproenkephalin-knockout (PPEKO) mice and their wild-ty

17 Preproenkephalin levels in ak mice were elevated in both

18 -Acb NPY reduced neuronal firing, as well as preproenkephalin messenger RNA expression in the striatu

19 d dynorphin neurons and the effect of NPY on preproenkephalin messenger RNA levels in the striatum us

20 nt with the post-translational processing of preproenkephalin, met-enkephalin was more abundant than

21 ST-ir neurons contained GAD-67 mRNA (<1%) or preproenkephalin mRNA (6%).

22 nd 48 h duration, and hypothalamic levels of preproenkephalin mRNA as well as methionine enkephalin w

23 tal regions with abundant branching, whereas preproenkephalin mRNA expression increased in severely d

24 Furthermore, normal preproenkephalin mRNA expression was maintained despite

25 ylase-immunoreactive fibers, upregulation of preproenkephalin mRNA expression, and compensatory chang

26 sure to nitrous oxide (N2O) on the levels of preproenkephalin mRNA in the hypothalamus of rats was ex

27 proenkephalin mRNA levels, (b) the increased preproenkephalin mRNA levels appear to be proportional t

28 animals exhibited significant elevations in preproenkephalin mRNA levels in the hypothalamus.

29 O exposure, and (c) N2O-induced elevation in preproenkephalin mRNA levels is associated with correspo

30 to N2O results in significant elevations in preproenkephalin mRNA levels, (b) the increased preproen

31 of AD) were increased in hAPP mice, as were preproenkephalin mRNA levels.

32 sed rats exhibited significant elevations in preproenkephalin mRNA levels.

33 The levels on preproenkephalin mRNA were significantly higher after 48

34 pping distribution with substance P mRNA and preproenkephalin mRNA, both markers for the shell and co

35 reprotachykinin neurons but only a subset of preproenkephalin neurons, suggesting preferential locali

36 -defective HSV-based vector expressing human preproenkephalin (PENK) in subjects with intractable foc

37 Expression of the mu-opioid receptor (MOR), preproenkephalin (PENK), and the dopamine transporter wa

38 ereas oxotremorine augments, AMPH-stimulated preproenkephalin (PPE) gene expression in striatopallida

39 a novel nuclear RNA species derived from the preproenkephalin (PPE) gene.

40 endogenous opioids preprodynorphin (PPD) and preproenkephalin (PPE) in fetal monkey brains.

41 the rVRG that contained both VGLUT2 mRNA and preproenkephalin (PPE) mRNA as revealed by double in sit

42 DA) denervation and coincident expression of preproenkephalin (PPE) mRNA in monkeys made parkinsonian

43 te brain sections were processed for CCK and preproenkephalin (PPE) mRNA in situ hybridization histoc

44 male rats have shown that estrogen increases preproenkephalin (PPE) mRNA levels in the ventrolateral

45 rotransmission on preprotachykinin (PPT) and preproenkephalin (PPE) mRNA levels were examined in subr

46 on the basis of whether these cells contain preproenkephalin (PPE) mRNA or project to the spinal cor

47 Using probe for preproenkephalin (PPE) mRNA that encodes OGF, and in sit

48 on of glutamic acid decarboxylase (GAD67) or preproenkephalin (PPE) mRNA using in situ hybridization.

49 n gene expression, Northern blot analysis of preproenkephalin (PPE) mRNA was conducted in tissue samp

50 lbospinal (BSBS) neurons of the RVLM express preproenkephalin (PPE) mRNA.

51 y was observed in a construct containing the preproenkephalin (PPE) promoter.

52 f LID including striatal preprodynorphin and preproenkephalin (PPE), and on the integrity of dopamine

53 eprodynorphin (PPD), preprotachykinin (PPT), preproenkephalin (PPE), and secretogranin II (SGII) mRNA

54 Northern analysis of preprotachykinin (PPT), preproenkephalin (PPE), and zif/268 mRNAs, as well as HP

55 Messenger RNA for preproenkephalin (PPE), the precursor of OGF, was detect

56 We have previously shown that the preproenkephalin (ppENK) and p16 genes are aberrantly me

57 chain reaction (PCR) that striatal mRNA for preproenkephalin (PPENK) and preprodynorphin (PPDYN) in

58 in discrete brain regions which are high in preproenkephalin (PPENK) mRNA content and/or are importa

59 ptor blockade, by RU 486, increases striatal preproenkephalin (PPenk) mRNA levels.

60 a functional gene for the endogenous ligand preproenkephalin (ppENK) show a similar tolerance defici

61 Rats infected with the virus expressing preproenkephalin showed a selective, naloxone-reversible

62 erations between liganded TRs and ERs affect preproenkephalin transcription.

63 cDNA for an opioid peptide precursor, human preproenkephalin, under control of the human cytomegalov

64 Both preproenkephalin wild type (ppENK [+/+]) and knockout (p