ライフサイエンスコーパス: prereplication complex

1 site of DNA replication and formation of the prereplication complex.

2 n of replication start sites relative to the prereplication complex.

3 endent kinases (CDKs), and components of the prereplication complex.

4 m a single nucleoprotein assembly called the prereplication complex.

5 loading of the initiation factor Cdc45 onto prereplication complexes.

6 in-bound signal that prevents reformation of prereplication complexes.

7 se systems function by blocking formation of prereplication complexes.

8 18 is a conserved and essential component of prereplication complexes.

9 state was unable to assemble into productive prereplication complexes.

10 ccompanied by hyperphysiological assembly of prereplication complexes.

11 ich suggests that Cdc45p associates with the prereplication complex after activation of S-phase cycli

12 cation origins, establishing the role of the prereplication complex and origin recognition complex (O

13 RecQL appears to associate with prereplication complexes and be recruited to ori-Lyt thr

14 from G0 quiescent phase, for the assembly of prereplication complexes and for endoreduplication in me

15 DNA was incubated in egg cytosol to form prereplication complexes and then in nucleoplasmic extra

16 omplex (ORC) selects the genomic sites where prereplication complexes are assembled and DNA replicati

17 Prereplication complexes are assembled at eukaryotic ori

18 Prereplication complexes are assembled on all origins in

19 The prereplication complexes are recruited to ori-Lyt DNA th

20 Specifically, p16ink4a disrupts prereplication complex assembly by inhibiting mini-chrom

21 ction of multiple G1 CDK complexes regulates prereplication complex assembly.

22 e loading of Cdc45p and RPA onto a preformed prereplication complex at each origin with preprogrammed

23 DNA synthesis: first, as a component of the prereplication complex at origins and, then, as a helica

24 in usage and the time required to reassemble prereplication complexes at replication origins.

25 ition complexes (ORCs) and the appearance of prereplication complexes at specific sites.

26 ARP-1, DNA-PK, and Ku86 were not detected in prereplication complexes but were present in replication

27 MCM2-7 proteins and other components of the prereplication complex by cell cycle-dependent protein k

28 isrupts chromatin binding of pre-IC, but not prereplication complex, components.

29 cation compartment, where RTA interacts with prereplication complexes composed of at least six core m

30 ication requires the previous formation of a prereplication complex containing the ATPase Cdc6 and th

31 failed to incorporate MCM helicase into DNA prereplication complex during G(0) --> S phase progressi

32 colocalizes with Orc2, which is part of the prereplication complex, during G1.

33 ported into the nucleus to be assembled into prereplication complexes, during a period of low cyclin-

34 xtracts supplemented with HsORC1-5 supported prereplication complex formation and X. laevis sperm DNA

35 ng that the mitotic kinase activity inhibits prereplication complex formation in human cells.

36 L in regulating CDT1, a protein required for prereplication complex formation.

37 Initiation depends on the assembly of the prereplication complex in late M phase and activation in

38 significant role in regulating reassembly of prereplication complexes in mammalian cells, as it does

39 ication fidelity by blocking the assembly of prereplication complexes in the S and G(2) phases of the

40 rst 24 h of RB activation, components of the prereplication complex, initiation factors, and the clam

41 Formation of this prereplication complex is an essential step toward the c

42 In the absence of H2B ubiquitylation, the prereplication complex is formed and activated, but repl

43 ver, Mcm10 interacts with key members of the prereplication complex: Mcm2, Dup (Cdt1), and Orc2.

44 PA, suggesting that RB does not regulate the prereplication complex or disrupt early initiation event

45 replication involves the establishment of a prereplication complex (pre-RC) and subsequent activatio

46 During the G(1) phase of the cell cycle, a prereplication complex (pre-RC) consisting of ORC, Cdc6,

47 implicated in DNA replication elongation and prereplication complex (pre-RC) formation, respectively.

48 cohesin are loaded onto dsDNA containing the prereplication complex (pre-RC) generated in vitro by Xe

49 microarray analysis that the transcripts of prereplication complex (pre-RC) genes are elevated compa

50 mplex (ORC) is an essential component of the prereplication complex (pre-RC) in mitotic cell cycles.

51 RC) and Cdc6, which are required to create a prereplication complex (pre-RC), are dispensable.

52 ection on the formation of the host cell DNA prereplication complex (pre-RC).

53 Xic1 turnover requires the formation of a prereplication complex (pre-RC).

54 enting the incorporation of MCM complex into prereplication complex (pre-RC).

55 DNA bending proteins, Fis and IHF, comprise prereplication complexes (pre-RC) that unwind the Escher

56 , Cdc45p, and MCM proteins are components of prereplication complexes (pre-RC).

57 In eukaryotic cells, prereplication complexes (pre-RCs) are assembled on chro

58 n is dependent on the prior establishment of prereplication complexes (pre-RCs) at origins of replica

59 ation in eukaryotes requires the assembly of prereplication complexes (pre-Rcs) at the origins of rep

60 ost of the cell cycle and direct assembly of prereplication complexes (pre-RCs) before the onset of S

61 In eukaryotes, prereplication complexes (pre-RCs) containing ORC, Cdc6,

62 t appeared to be two independently assembled prereplication complexes (pre-RCs) for DNA replication:

63 DNA in egg extract requires the assembly of prereplication complexes (pre-RCs) on sperm chromatin.

64 ryotic cells, as it allows the activation of prereplication complexes (pre-RCs) that contain the MCM

65 unknown mechanism targeting the function of prereplication complexes (pre-RCs) to acutely block S-ph

66 romatin during replication initiation, after prereplication-complex (pre-RC) proteins, Cut5, Sld5, or

67 , we mapped replication initiation sites and prereplication complex protein binding within the ~10-kb

68 The binding of the prereplication complex proteins Orc1, Orc2, Mcm3, Mcm7,

69 This complex is a key component of the prereplication complex that assembles at replication ori

70 ation origin during G1 phase by assembling a prereplication complex that contains a Mcm2-7 (minichrom

71 rrent models for the conversion of E1 in the prereplication complex to a hexameric helicase assembly.

72 (MCM) proteins are required for establishing prereplication complexes, upon which initiation is trigg

73 This influence of p16ink4a on the prereplication complex was dependent on the presence of

74 address this question, chromatin containing prereplication complexes was driven into mitosis with Cd

75 as sufficient to restore the assembly of the prereplication complex yet failed to promote S-phase pro