ライフサイエンスコーパス: presynaptic

1 ng state-of-the-art techniques, we show that presynaptic 5-HT function is altered in these mice, and

2 al and the oxoreductase-dependent control of presynaptic actin.

3 ere unaffected by the peptides, indicating a presynaptic action on glutamate release.

4 The shape of the presynaptic action potential (AP) has a strong impact on

5 Intriguingly, the loss of the presynaptic active zone proteins Piccolo and Bassoon tri

6 ls to release-ready synaptic vesicles at the presynaptic active zone, which is localized at the base

7 nt voltage-gated Ca(2+) channel densities in presynaptic active zones (AZs) underlie different Pr val

8 ting molecules (RIMs) provide scaffolding at presynaptic active zones and are involved in vesicle pri

9 phagy of synaptic vesicles and components of presynaptic active zones is regulated.

10 ticity of EPSPs with increasing frequency of presynaptic activity allowed inhibition to be overcome t

11 In slices, five pairings of subthreshold presynaptic activity and calcium (Ca(2+)) plateau potent

12 the sense that weight changes depend on the presynaptic activity and the error signal projected onto

13 ory response defined an optimum frequency of presynaptic activity for spike transfer at approximately

14 in PE animals was not rescued by increasing presynaptic activity, which actually led to LTP in PE an

15 postsynaptic target recognition by incoming presynaptic afferents.

16 omozygous stargazer (stg/stg) mice bearing a presynaptic AMPA receptor defect, but not homozygous tot

17 n the spines, in addition to the traditional presynaptic and astrocytic locations.

18 ally shifting the resting potentials of both presynaptic and postsynaptic cells.

19 Fourth, both presynaptic and postsynaptic entities are significantly

20 We observed presynaptic and postsynaptic localization of all APP fam

21 econsolidation), reverses the cocaine-evoked presynaptic and postsynaptic modifications in PL-mPFC an

22 These findings indicate selective presynaptic and postsynaptic Nav expression in glutamate

23 of stimulus size on the spiking activity of presynaptic and postsynaptic neurons.

24 ed in the PVN and contributes to potentiated presynaptic and postsynaptic NMDAR activity to elevate s

25 isplay notable subcellular colocalization at presynaptic and postsynaptic regions.

26 Pairing presynaptic and postsynaptic spikes at 6-10 Hz reliably

27 bidirectionally orchestrate the function of presynaptic and postsynaptic terminals.

28 aine place conditioning increases excitatory presynaptic and postsynaptic transmission in rat PL-mPFC

29 e ON cell combines signal and noise from its presynaptic arrays of bipolar and amacrine cells less ef

30 iciency of the ON cell is compensated by its presynaptic arrays providing a higher SNR than the array

31 f signal-to-noise power ratio (SNR) from its presynaptic arrays to its postsynaptic currents.

32 nding peptide derived from Bassoon inhibited presynaptic autophagy in boutons lacking Piccolo and Bas

33 Bassoon was associated with the induction of presynaptic autophagy, a process that depended on poly-u

34 LOF) of Bassoon alone suppressed or enhanced presynaptic autophagy, respectively, implying a fundamen

35 hts into the molecular mechanisms regulating presynaptic autophagy.

36 role for Bassoon in the local regulation of presynaptic autophagy.

37 ieved to increase dopamine signaling through presynaptic autoreceptor blockade.

38 As different combinations of presynaptic axons may be active during consecutive cycle

39 he molecular and functional heterogeneity of presynaptic AZs.

40 ustly increases the number of parallel fiber presynaptic boutons and functional parallel fiber/Purkin

41 use and monkey V1 do not differ, the size of presynaptic boutons are significantly larger in monkey V

42 Presynaptic, but not postsynaptic, loss of vti1a and VAM

43 tina but dramatically reduced the density of presynaptic Ca(2+) channels, decreased and desynchronize

44 rtex to the brainstem.SIGNIFICANCE STATEMENT Presynaptic Ca(2+) entry via voltage-activated calcium c

45 o regulate transmitter release by inhibiting presynaptic Ca(2+) influx.

46 vere alterations in action potential-induced presynaptic Ca(2+) transients (somatostatin-positive syn

47 rovide genetic evidence suggesting a complex presynaptic Ca(2+)-dependent signaling network underlyin

48 homophilic interactions, our results suggest presynaptic cadherin-9 binds postsynaptic cadherins-6 an

49 emonstrate that MCTP functions downstream of presynaptic calcium influx with separable activities to

50 ation of Nrxns produces a robust increase in presynaptic calcium levels and neurotransmitter release

51 resulting from impaired PS activity inhibits presynaptic calcium signal and neurotransmitter release,

52 Additionally, despite larger presynaptic calcium signals, we observed fewer evoked sp

53 cells during olfactory conditioning reduces presynaptic calcium transients in dopamine neurons, a fi

54 ons had more associated vesicles and reduced presynaptic calcium-channel clustering.

55 pted the one-to-one signal transmission from presynaptic calyces to postsynaptic MNTB neurons and ind

56 trol the one-to-one signal transmission from presynaptic calyces to postsynaptic MNTB neurons.

57 eins that form tripartite complexes with the presynaptic cell-adhesion molecules neurexins or 'delete

58 immunolabelling shows the dynamics of these presynaptic centromere associations and a structural reo

59 Such a specific presynaptic change, which may constitute a part of the c

60 apses to respond to stimulation by elevating presynaptic choline uptake and releasing acetylcholine i

61 Here, we show that the capacity of presynaptic cholinergic synapses to respond to stimulati

62 ght VAMP1 homozygous mutations as a cause of presynaptic CMS.

63 vesicle binding domain still localize to the presynaptic compartment but do not impair synaptic funct

64 nds to and internalizes its light chain into presynaptic compartments with exquisite specificity.

65 behavior and dynamics of human RAD52 during presynaptic complex assembly and disassembly.

66 ween human RPA (hRPA) and human RAD51 during presynaptic complex assembly and disassembly.

67 We also found that during presynaptic complex assembly, most of the RPA and RAD52

68 investigations into the regulation of human presynaptic complex assembly.

69 sulting nucleoprotein filament, known as the presynaptic complex, is responsible for pairing the ssDN

70 red the fate of RAD52 during assembly of the presynaptic complex.

71 Astrocytic phagocytosis, mainly of presynaptic components of large synapses, increased afte

72 F1A is required for axonal transport of many presynaptic components to synapses, and mutation of this

73 report 2 families with undiagnosed recessive presynaptic congenital myasthenic syndrome (CMS).

74 scores the critical importance of fine-tuned presynaptic control in normal brain function.

75 crease in spontaneous release frequency, and presynaptic Cortactin is necessary for the rapid potenti

76 Furthermore, animals lacking presynaptic Cortactin show a decrease in spontaneous rel

77 ntial learning-related in vivo modulation of presynaptic corticostriatal function.

78 -derived neurotrophic factor (BDNF)/TrkB and presynaptic cyclic AMP (cAMP)/PKA signaling.

79 encoded pH indicator, named 'pHerry', in the presynaptic cytosol revealed acid efflux following nerve

80 mporal limits on DA action, and provides for presynaptic DA recycling to replenish neurotransmitter p

81 n can be sustained by glycolysis, but strong presynaptic demands are met preferentially by oxidative

82 how defects in vesicle distribution near the presynaptic dense projection, with fewer undocked vesicl

83 APLP1 or APLP2 in non-neuronal cells induces presynaptic differentiation in contacting axons of cocul

84 SF21 interacts with neurexin2alpha to induce presynaptic differentiation of inhibitory synapses, and

85 that IgSF21 selectively regulates inhibitory presynaptic differentiation through interacting with pre

86 vements of growth cone filopodia and impairs presynaptic differentiation.

87 protein that selectively induces inhibitory presynaptic differentiation.

88 rotonin concentrations are determined by the presynaptic dopamine (DAT) and serotonin (SERT) transpor

89 aphy studies that have investigated striatal presynaptic dopamine function in Parkinson disease (PD)

90 ast 3 weeks of placebo treatment, along with presynaptic dopamine synthesis capacity (ie, DOPA decarb

91 The ability of presynaptic dopamine terminals to tune neurotransmitter

92 u-opioid receptor availability together with presynaptic dopaminergic defects.

93 EDS was also associated with presynaptic dopaminergic dysfunction, whereas biofluid m

94 isolation and childhood trauma, also affect presynaptic dopaminergic function.

95 ET allows assessment of the integrity of the presynaptic dopaminergic pathway.

96 Presynaptic dorsal raphe neuron (DRN) 5-HT1A receptors a

97 Here, we identify a presynaptic effector molecule of the Wingless/Wnt signal

98 ent of synaptic plasticity is accompanied by presynaptic effects that disrupt the excitatory/inhibito

99 the synapsin-dependent reserve pool and the presynaptic endocytosis machinery.

100 Divergent somatic and presynaptic engagement in both projections during early

101 cunosum-moleculare, which form synapses with presynaptic entorhinal cortex afferents.

102 ronal activity drives net Ca(2+) uptake into presynaptic ER although this activity does not contribut

103 These experiments reveal a critical role of presynaptic ER in the control of neurotransmitter releas

104 SWI/SNF was previously shown to regulate presynaptic events in HR, but its function in these even

105 plied after injury normalizes spine density, presynaptic excitability, and inhibitory inputs at injur

106 Moreover, the theory predicts presynaptic expression of long-term depression, consiste

107 enotypes in aipr-1 mutants can be rescued by presynaptic expression of mouse AIP, demonstrating that

108 eceptor subunit GluA4, which is regulated by presynaptic expression of the synaptogenic immediate ear

109 es release of ADP to help maintain an active presynaptic filament.

110 ostsynaptic action potentials in response to presynaptic firing.

111 neurons, coexists in the same pathway with a presynaptic form of GABAergic LTP, while interneurons of

112 luble cytosolic proteins vital to axonal and presynaptic function are synthesized in the neuronal som

113 This highlights a presynaptic function for LRP4, enabling deeper understan

114 is and oxidative phosphorylation, in fueling presynaptic function in unclear.

115 Our experiments revealed that presynaptic function is tightly controlled by ER Ca(2+)

116 We previously showed that sustained presynaptic function requires activity-driven glycolysis

117 namic regulation of synaptic transmission by presynaptic G-protein coupled receptors shapes informati

118 cannabinoid (CB1) receptors known to inhibit presynaptic GABA release was significantly reduced in th

119 tein kinase A (PKA)-dependent enhancement of presynaptic GABA release.

120 atter of which can be suppressed by reducing presynaptic GABAB receptors.

121 ization, as animals with genetically deleted presynaptic GABAB(1a) receptors cannot discriminate betw

122 e that selective deficits in the activity of presynaptic GABABRs contribute to the pathophysiology of

123 A three-dimensional morphometric analysis of presynaptic glutamatergic boutons and dendritic spines w

124 ses is thought to be critically dependent on presynaptic glutamatergic signaling.

125 The presynaptic, high-affinity choline transporter is a crit

126 Presynaptic homeostatic plasticity (PHP) controls synapt

127 Presynaptic homeostatic plasticity is a conserved form o

128 show that Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasm

129 synapses still retain the ability to express presynaptic homeostatic plasticity, a fundamental and ad

130 red pyramidal neurons followed by retrograde presynaptic hyper-excitability.

131 ce, observing neurophysiological features of presynaptic impairment, similar to the patients.

132 ly low compound muscle action potentials and presynaptic impairment.

133 1 h) had initially been explained either by presynaptic increases in glutamate release or by direct

134 s of, respectively, Ia afferent synapses and presynaptic inhibition (P-boutons) on retrogradely label

135 Rbeta in inhibitory neurons leads to reduced presynaptic inhibition and changes to sensory-evoked ref

136 tion of Ia afferent synapses and a change in presynaptic inhibition could contribute to maintain or e

137 Previous research shows that GABA-mediated presynaptic inhibition has a critical role in cued fear

138 a-containing GABABRs are believed to mediate presynaptic inhibition in principal neurons.

139 These data suggest that GABA-mediated presynaptic inhibition is not critical for retrieval of

140 This includes presynaptic inhibition of local glutamatergic release fr

141 ly coordinated enkephalin- and GABA-mediated presynaptic inhibition of somatosensory neurons.

142 es on regenerating motoneurons and decreased presynaptic inhibitory control.

143 The presynaptic inhibitory metabotropic glutamate receptors

144 of layer 2/3 pyramidal neurons to simulated presynaptic input with different types of STP, and then

145 nstruct the time-varying synaptic weights of presynaptic inputs for different types of STP.

146 cending inhibitory and descending excitatory presynaptic inputs onto MGB neurons, likely increasing g

147 naptic efficacy during a continuous train of presynaptic inputs, despite synaptic depression.

148 rofile mesolimbic dopamine neurons and their presynaptic inputs, we injected Cre-conditional GFP viru

149 nd Poisson-distributed (4 Hz mean) trains of presynaptic inputs.

150 a biophysically unrestrained function of the presynaptic inter-spike intervals.

151 opioid neuropeptide dynorphin, which acts at presynaptic kappa-opioid receptors (KORs) on dopaminergi

152 ocal inhibitory mechanisms and activation of presynaptic KORs in the ventral striatum (VS).

153 n is depolarization-mediated inactivation of presynaptic Kv1-family potassium channels, leading to ac

154 n tuning in V1 was not inherited from single presynaptic LGN cells, suggesting that it must emerge ex

155 e exclusively from the combined input of all presynaptic LGN cells.

156 complex regulation of BACE1 trafficking and presynaptic localization through Snapin-mediated dynein-

157 derlying forms of synaptic plasticity with a presynaptic locus.

158 activating presynaptic NMDARs, and promotes presynaptic long-term depression.

159 We show this is not the case for hippocampal presynaptic long-term potentiation (LTPpre), which is ex

160 Loss of presynaptic LRP4 reduces excitatory (not inhibitory) syn

161 imaging approach in Drosophila to study the presynaptic machinery responsible for these vesicular pr

162 A presynaptic mechanism mediated by distinct intracellular

163 apse numbers via a postsynaptic instead of a presynaptic mechanism, which was surprising given its pr

164 ic synapses through an alpha7nAChR-dependent presynaptic mechanism.

165 Synaptic vesicles (SVs) fuse with the presynaptic membrane (PM) at specialized regions called

166 However, translocation occurs from presynaptic membranes other than synaptic vesicles and i

167 At the first synapse in the visual system, presynaptic metabotropic glutamate receptors (mGluRs) re

168 lease probability is negatively regulated by presynaptic mGluR2/3, and sucrose reinstatement was pote

169 Therefore, presynaptic mitochondrial function is critical for the s

170 Intact presynaptic mitochondrial function is critical for the s

171 indicating that increased enkephalin tone on presynaptic mu opioid receptors was responsible for occl

172 euron, Moehle et al. (2017) demonstrate that presynaptic muscarinic receptors counteract the effects

173 Presynaptic nAChR activation increased responses evoked

174 letion of intersectin 1/2 in mice alters the presynaptic nanoscale distribution of synapsin I and cau

175 transmission, the influx of Ca(2+) into the presynaptic nerve terminal activates a Ca(2+) sensor for

176 of the brain's vast number of synapses, the presynaptic nerve terminal, synaptic cleft, and postsyna

177 ered, and specific effects were found on the presynaptic nerve terminals at the neuromuscular junctio

178 lpha-Synuclein (aS) is a protein abundant in presynaptic nerve terminals in Parkinson disease (PD) an

179 grate neuronal activity and pH regulation in presynaptic nerve terminals.

180 determined by transient Ca(2+) elevations in presynaptic nerve terminals.

181 tic differentiation through interacting with presynaptic neurexin2alpha and plays a crucial role in s

182 e relevance of the proteolytic processing of presynaptic neurexins (Nrxns) in glutamatergic different

183 Presynaptic neurexins regulate synapse properties via di

184 zed transsynaptic interactions are formed by presynaptic neurexins, which bind to diverse postsynapti

185 ynaptic cell-adhesion molecules that bind to presynaptic neurexins.

186 c cell adhesion molecules that interact with presynaptic neurexins.

187 VAMP1 is crucial for vesicle fusion at presynaptic neuromuscular junction (NMJ).

188 subsequent neurotransmitter release from the presynaptic neuron.

189 escribes the location and impact of aging on presynaptic neuronal nicotinic acetylcholine receptors (

190 AAV1-Cre from transduced presynaptic neurons effectively and specifically drives

191 ograde transsynaptic viruses for identifying presynaptic neurons of transduced neurons, analogous ant

192 bined with optogenetic activation of defined presynaptic neurons, CaMPARI provides an all-optical met

193 Our data indicate that NRAP-1, secreted from presynaptic neurons, localizes to glutamatergic synapses

194 neurons, the virus serially labels chains of presynaptic neurons.

195 diate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscula

196 predominantly GABAergic currents mediated by presynaptic nicotinic receptors or biphasic GABAergic an

197 Presynaptic NMDA receptors (preNMDARs) control synaptic

198 ere, we report that MC-GC synapses undergo a presynaptic, NMDA-receptor-independent form of long-term

199 elease occurs, it decreases Pr by activating presynaptic NMDARs, and promotes presynaptic long-term d

200 We show that activation of presynaptic Nrxns with postsynaptic Nlgn1 or inhibition

201 cific dominant-negative constructs in either presynaptic or postsynaptic neurons.

202 eurotransmission dynamically from either the presynaptic or the postsynaptic site.

203 Deleting IgSF21 in mice impairs inhibitory presynaptic organization, especially in the hippocampal

204 The activity of presynaptic organizing molecules signaling to downstream

205 phagocytosis of synaptic elements, mostly of presynaptic origin and in large synapses, is upregulated

206 ptic neurons establish connections with each presynaptic partner independently or balance inputs to a

207 Convergent input from different presynaptic partners shapes the responses of postsynapti

208 Synaptojanin 1 (SJ1) is a major presynaptic phosphatase that couples synaptic vesicle en

209 the rates of primed vesicle fusion with the presynaptic plasma membrane and synaptic vesicle pool re

210 aneous fusion of a synaptic vesicle with the presynaptic plasma membrane.

211 As expected, CB1 immunoparticles appeared at presynaptic plasmalemma, making asymmetric and symmetric

212 Our findings reveal a novel framework of presynaptic plasticity that radically differs from tradi

213 b) is a target-derived signal that acts upon presynaptic plexin B (PlexB) receptors to mediate the re

214 mmunoreactivity was selectively expressed in presynaptic profiles, while Nav 1.2 and Nav 1.6 were exp

215 NT Target cell type-dependent variability in presynaptic properties is an intriguing feature of corti

216 m presynaptic terminals by signaling through presynaptic protein tyrosine phosphatase receptor delta.

217 cells, vesicular glutamate transporter 1, a presynaptic protein, in mitral and tufted projection neu

218 etagamma subunits (Gbetagamma) interact with presynaptic proteins and regulate neurotransmitter relea

219 hlight the differential deployment of shared presynaptic proteins in neuronal cell type-specific func

220 The loss of presynaptic proteins Munc18-1, syntaxin-1, or SNAP-25 is

221 ling, photoreceptor synapses use specialized presynaptic proteins that support neurotransmission at a

222 globus pallidus-evoked inputs is mediated by presynaptic receptors.

223 Whereas the presynaptic recruitment and activation of Munc13-1 depen

224 aling in dopamine neurons is involved in the presynaptic regulation of dopamine levels.

225 cally at the Drosophila NMJ and that it is a presynaptic regulator of rapid activity-dependent modifi

226 (2+) sources, with critical contributions of presynaptic release and its permeation through Ca(2+)- (

227 main shedding in axonal Nrxn1-beta increases presynaptic release at individual terminals, likely refl

228 ptic acetylcholine receptors (AChRs) impacts presynaptic release by establishing a genetically engine

229 Importantly, inactivation of PS inhibits presynaptic release downstream of Nrxn activation, leavi

230 of this efferent inhibition by enhancing the presynaptic release of acetylcholine.

231 n all mammalian central neurons, controlling presynaptic release of transmitter, postsynaptic signali

232 rotransmitter receptors and had no effect on presynaptic release probabilities.

233 Target cell type-dependent differences in presynaptic release probability (Pr ) and short-term pla

234 electively and persistently up-regulated the presynaptic release probability of BLA-to-FSI synapses,

235 Changes in presynaptic release properties may result from dysfuncti

236 xcitability, loss of inhibition and enhanced presynaptic release through netrin-1.

237 was accounted for by increases in excitatory presynaptic release, paired-pulse facilitation, and incr

238 ceptors leads to a retrograde enhancement in presynaptic release.

239 ns as neurotransmitters and demonstrate that presynaptic released protons modulate synaptic transmiss

240 Presynaptic rescue of Syt7 expression restores both faci

241 the majority of these tips are proximal to a presynaptic rod release site, suggesting more rods provi

242 y, of dopamine synthesis, supporting a major presynaptic role for D2S.

243 Our work uncovers a presynaptic role of Tau that may be part of the early pa

244 13-1 and bMunc13-2-mediate opposite forms of presynaptic short-term plasticity and thus differentiall

245 laminin receptor, integrin alpha3, is at the presynaptic side of the wild-type OPL.

246 ctions of PIP2 at postsynaptic as opposed to presynaptic sites.

247 g inputs is determined by the interaction of presynaptic spike times with the short-term dynamics of

248 fferences in postsynaptic spike responses to presynaptic spikes following short vs long inter-spike i

249 gical or genetic deletion of Kv1.1 broadened presynaptic spikes without preventing further prolongati

250 s a function of time based on the history of presynaptic spikes.

251 ostsynaptic potentials or currents evoked by presynaptic spikes.

252 tic spikes that are precisely time locked to presynaptic spikes.

253 the juxtacellular mode was efficient at low presynaptic stimulation frequency and appeared insensiti

254 potentials (AP-bursts) paired with preceding presynaptic stimulation in stratum radiatum specifically

255 sent a model for RecN function that includes presynaptic stimulation of the bacterial repair pathway

256 rains of action potentials in the absence of presynaptic stimulation.

257 Hair cells have a unique presynaptic structure, the synaptic ribbon, which organi

258 e were alterations in the number and size of presynaptic structures for the three primary neurotransm

259 instead of making normal spiny synapses, the presynaptic structures in betaIII spectrin-depleted neur

260 not simply the presence of Cortactin in the presynaptic terminal but its increase that is necessary

261 fuse at morphological specializations in the presynaptic terminal termed active zones (AZs).

262 CaV2.1 null background at the calyx of Held presynaptic terminal.

263 ate throughout the soma, dendrites, axon and presynaptic terminal.

264 dritic spines that are not in contact with a presynaptic terminal.

265 ormally high cytosolic calcium transients in presynaptic terminals and deficient working memory but d

266 release did not disrupt the morphogenesis of presynaptic terminals and dendritic spines, suggesting t

267 neurotransmission by recapturing DA into the presynaptic terminals and is a principal target of the p

268 P neurons reduces autophagic accumulation at presynaptic terminals by enhancing AV retrograde transpo

269 clustering factor neuronal pentraxin 1 from presynaptic terminals by signaling through presynaptic p

270 Surprisingly, the density of presynaptic terminals is not affected by betaIII spectri

271 generation of Nrxn-CTF, which accumulate at presynaptic terminals lacking PS function.

272 lated alpha-synuclein deposits were found in presynaptic terminals mainly in the form of small aggreg

273 osphorylated alpha-synuclein is found at the presynaptic terminals of dementia with Lewy bodies cases

274 opamine receptor subtype 1 (D1) signaling in presynaptic terminals of direct pathway striatal spiny p

275 -mu treatment supported hDAT delivery to the presynaptic terminals of dopaminergic neurons and restor

276 Presynaptic terminals of incipient synaptic contacts gen

277 anin B, which are normally found in neuronal presynaptic terminals storing catecholamines such as dop

278 These features allow presynaptic terminals to translate complex firing freque

279 plays a critical role in removing BACE1 from presynaptic terminals toward the soma, thus reducing syn

280 The number of opposed excitatory presynaptic terminals was sharply reduced upon postsynap

281 been thought to be transported to axons and presynaptic terminals where they signal via ErbB3/4 rece

282 ures encompassing branch points and numerous presynaptic terminals with undefined molecular partners

283 ity can result in transient acidification of presynaptic terminals, and such shifts in cytosolic pH (

284 ransmitter release.SIGNIFICANCE STATEMENT In presynaptic terminals, neurotransmitter release is dynam

285 As neuronal activity drives acid loading in presynaptic terminals, we hypothesized that the same act

286 1 trafficking in axons and APP processing at presynaptic terminals.

287 he removal of BACE1 from distal AD axons and presynaptic terminals.

288 ne, while UNC5C may alter the composition of presynaptic terminals.

289 resulting in markedly reduced expression at presynaptic terminals.

290 ivity produces large and rapid acid loads in presynaptic terminals.

291 usly recorded the extracellular potential of presynaptic thalamic cells and the intracellular potenti

292 rrays providing a higher SNR than the arrays presynaptic to the OFF cell, apparently to improve visua

293 signal-to-noise power ratio (SNR) than those presynaptic to the OFF sustained alpha cell.

294 KEY POINTS: Bipolar and amacrine cells presynaptic to the ON sustained alpha cell of mouse reti

295 lice cultures that are essentially devoid of presynaptic transmitter release, we demonstrate that the

296 which could be involved in the modulation of presynaptic transmitter release.

297 notoxin-MVIIC, consistent with inhibition of presynaptic TRPV1 channels by alpha2 adrenergic receptor

298 We suggest that modulation of presynaptic TRPV1 channels in nociceptive neurons by des

299 The majority of ribbon markers, presynaptic vesicular release and postsynaptic neurotran

300 ts with rod ON-bipolar cells by aligning the presynaptic voltage-gated Ca(2+) channel directing gluta