ライフサイエンスコーパス: presynaptic membrane

1 vesicles of the synaptic vesicle pool to the presynaptic membrane.

2 t did not label presynaptic terminals or the presynaptic membrane.

3 usion event that joins synaptic vesicles and presynaptic membrane.

4 gulate or facilitate vesicle delivery to the presynaptic membrane.

5 edistributed synaptic vesicles closer to the presynaptic membrane.

6 oteins to anchor active-zone proteins to the presynaptic membrane.

7 density in mitochondrial membrane facing the presynaptic membrane.

8 lieved to drive fusion of the vesicle to the presynaptic membrane.

9 cted eight-pass transmembrane protein in the presynaptic membrane.

10 ts by fusing to other vesicles docked at the presynaptic membrane.

11 t by flattening out and becoming part of the presynaptic membrane.

12 rs (SERT, NET, and DAT, respectively) in the presynaptic membrane.

13 s the collapse of synaptic vesicles into the presynaptic membrane.

14 n of neurotransmitter-filled vesicles at the presynaptic membrane.

15 fusion of neurotransmitter vesicles with the presynaptic membrane.

16 photoreceptors it attaches the ribbon to the presynaptic membrane.

17 whereas sGCbeta concentrates just inside the presynaptic membrane.

18 of proteins in the synaptic vesicles and the presynaptic membrane.

19 e machinery and morphological changes at the presynaptic membrane.

20 be explained solely by depolarization of the presynaptic membrane.

21 drolysis before they could be fused with the presynaptic membrane.

22 nct functions after vesicle docking with the presynaptic membrane.

23 d ultrastructural analysis of the effects on presynaptic membranes.

24 termine the resting electrical properties of presynaptic membranes.

25 Mpp4, PMCAs were lost from rod photoreceptor presynaptic membranes.

26 his ready supply of synaptic vesicles at the presynaptic membranes.

27 t realized through lateral inhibition across presynaptic membrane, (2) the constraint of a single rel

28 eurotransmitter-laden vesicles fuse with the presynaptic membrane and discharge their contents into t

29 After fusion of synaptic vesicles with presynaptic membrane and secretion of the contents of th

30 Ribbons, typically anchored to the presynaptic membrane and surrounded by tethered synaptic

31 a dense body, or ribbon, is anchored to the presynaptic membrane and tethers synaptic vesicles; func

32 ate the fusion of synaptic vesicles with the presynaptic membrane and the ensuing transmitter release

33 They bind to the presynaptic membrane and then translocate intracellularl

34 ity's base includes vesicles docked with the presynaptic membrane and thus presumably ready for relea

35 ld explain alpha-synuclein's localization to presynaptic membranes and raises the possibility that pe

36 defect is accompanied by an expansion of the presynaptic membrane, and a depletion of vesicles from t

37 es to each other, to calcium channels in the presynaptic membrane, and to synaptic vesicles docked on

38 are transported and primed to fuse with the presynaptic membrane are important to all chemical synap

39 rotransmitter-containing vesicles and on the presynaptic membrane are thought to underlie docking and

40 ers of elements were in direct proportion to presynaptic membrane area.

41 ors, even while moving en masse again to the presynaptic membrane as a prelude for another round of e

42 onnected to synaptic vesicles contacting the presynaptic membrane at sites where fusion does not occu

43 Synucleins are a family of presynaptic membrane binding proteins.

44 ble vesicles were not clustered close to the presynaptic membrane but instead were dispersed almost r

45 e vesicles are only briefly connected to the presynaptic membrane by a transient fusion pore.

46 associated (docked) at release sites of the presynaptic membrane, called active-zones.

47 crine cells, we have simultaneously measured presynaptic membrane capacitance changes and EPSCs.

48 Here, we address this issue by performing presynaptic membrane capacitance measurements together w

49 ly 60% of VDCCs are mobile while confined to presynaptic membrane compartments.

50 eatment parallels the rapid expansion of the presynaptic membrane consequent to the massive vesicle f

51 icles may help account for a greater vesicle-presynaptic membrane contact area during docking and a g

52 erlying AZ abnormalities including pervasive presynaptic membrane detachments and reduced synaptic ve

53 of voltage-activated Ca(2+) channels in the presynaptic membrane for neurotransmitter release, some

54 on puncta within an NMJ were attached to the presynaptic membrane from postnatal day 0 to adulthood,

55 havbeta3 receptors and SERTs are enriched in presynaptic membranes from several brain regions and tha

56 ch encodes Munc18-1, a core component of the presynaptic membrane-fusion machinery, cause infantile e

57 Presynaptic membranes have been marked by FM dyes in stu

58 munoreactivity was not found associated with presynaptic membranes in the inner plexiform layer and w

59 r Maxi-K) channels have been investigated in presynaptic membranes in Xenopus motoneurone-muscle cell

60 tion with CSPalpha and SNARE proteins on the presynaptic membrane interface.

61 the extruded hair cells, indicating that the presynaptic membrane is still attached to the postsynapt

62 assembly's shape relative to the AZM and the presynaptic membrane is the same vesicle to vesicle, whe

63 e postulate that tension on integrins in the presynaptic membrane is transduced mechanically into cha

64 Ca2+ metabolism and occurs via pores in the presynaptic membrane, large enough to allow efflux of ne

65 machinery that drives fusion of SVs with the presynaptic membrane, little progress has been made in u

66 he ribbon tethers numerous vesicles near the presynaptic membrane, most of the tethered vesicles are

67 mber of vesicles immediately adjacent to the presynaptic membrane near active zones was still reduced

68 at connected a subset of mitochondria to the presynaptic membrane near active zones.

69 rat GABA transporter GAT-1 is located in the presynaptic membrane of axons where it plays a role in t

70 ly at punctate sites located just inside the presynaptic membrane of each terminal bouton.

71 inhibition of synaptic vesicle fusion to the presynaptic membrane of human motor neurons are responsi

72 number of synaptic vesicles adjacent to the presynaptic membrane of inhibitory synapses without affe

73 hat chemical LTP increased the length of the presynaptic membrane of mossy fiber boutons, associated

74 Synaptic ribbons, found at the presynaptic membrane of sensory cells in both ear and ey

75 owed the protein in the cytoplasm and on the presynaptic membranes of the photoreceptor synapses.

76 rminals, with the mature process targeted to presynaptic membrane opposed to muscle, and an abnormall

77 release site or whether it remains bound to presynaptic membranes or proteins after its release.

78 However, translocation occurs from presynaptic membranes other than synaptic vesicles and i

79 ediated interaction between microtubules and presynaptic membrane plays a pivotal role during bouton

80 Synaptic vesicles (SVs) fuse with the presynaptic membrane (PM) at specialized regions called

81 ability of its membrane (VM) fusing with the presynaptic membrane (PM) when a nerve impulse arrives.

82 ating range, which means it is unlikely that presynaptic membrane potential controls transmitter rele

83 smitter typically graded with respect to the presynaptic membrane potential, but release can be maint

84 usion pumps, interact with an Mpp4-dependent presynaptic membrane protein complex that includes Veli3

85 The presynaptic membrane protein SNAP-25 colocalized with DA

86 When the presynaptic membrane protein syntaxin is coexpressed in

87 -associated protein of 25 kDa (SNAP-25) is a presynaptic membrane protein that has been clearly impli

88 The dopamine transporter (DAT) is a presynaptic membrane protein that regulates dopaminergic

89 nic lines overexpressing ROP and syntaxin, a presynaptic membrane protein, indicate that ROP interact

90 In the present study we investigated the presynaptic membrane protein, syntaxin-1, in circumvalla

91 hat is believed to play a critical role with presynaptic membrane proteins (SNAP-25 and syntaxin) dur

92 A subunit of P/Q-type Ca2+ channels with the presynaptic membrane proteins syntaxin and SNAP-25 in vi

93 in, and synaptotagmin, without affecting the presynaptic membrane proteins syntaxin and SNAP-25, or t

94 immobilized recombinant proteins and native presynaptic membrane proteins, we found that the synprin

95 is known about the molecular organization of presynaptic membrane proteins.

96 cate, vesicles from one neuron fuse with the presynaptic membrane releasing chemicals that signal to

97 , while the number of vesicles docked to the presynaptic membrane remained unchanged.

98 A, an SV GTPase involved in SV targeting and presynaptic membrane tethering.

99 ynaptic vesicles immediately adjacent to the presynaptic membrane, the pool that includes the docked

100 ilitate fusion of synaptic vesicles with the presynaptic membrane through formation of a soluble NSF

101 PPK16-containing DEG/ENaC channel modulates presynaptic membrane voltage and, thereby, controls calc

102 and modulates exocytosis through control of presynaptic membrane voltage.

103 WT alpha-syn binding to presynaptic membranes was not affected by phosphorylatio

104 arify whether it is also associated with the presynaptic membrane, we employed immunogold electron mi

105 d certain other proteins associated with the presynaptic membrane were absent from DA-IPC varicositie

106 m channels are known to form clusters at the presynaptic membrane where they mediate calcium influx,

107 e interactions between synaptotagmin and the presynaptic membrane, which are mediated by the basic re

108 s trigger very rapid endocytosis, retrieving presynaptic membrane with a time constant of 470 ms.

109 ) sensor protein that binds to and bends the presynaptic membrane with its C2B domain, and thereby in

110 disrupts a Ca(2+) extrusion mechanism at the presynaptic membranes, with ensuing adaptive responses b

111 ld that enhances delivery of vesicles to the presynaptic membrane without requiring an active transpo