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1 patients with UBC, many of whom were heavily pretreated.
3 lete remissions in a large subset of heavily pretreated adult patients and the vast majority of child
9 m eight contaminated sites were prepared and pretreated, analyzed pretrial, spiked with diesel, place
10 activity of ceritinib in both ALK inhibitor-pretreated and ALK inhibitor-naive patients with ALK-rea
12 ous saccharification and fermentation of the pretreated and enzyme-digested residues surprisingly res
13 splant recipients who were not pretreated or pretreated and failed to downstage compared with propens
16 erapy showed encouraging efficacy in heavily pretreated and refractory patients with multiple myeloma
17 6 out of 7 monkeys, while 6 out of 7 3BNC117-pretreated animals became infected, although with signif
18 greater (p < 0.05) in anti-HSP27- and HSP70-pretreated animals compared with mice pretreated with co
21 al, we randomly assigned adults with heavily pretreated B-cell precursor ALL, in a 2:1 ratio, to rece
22 tween the pi* aromatic C horizontal lineC of pretreated barley straw adsorbent and pi* carbon atom in
23 om artificial contaminated water was done by pretreated barley straw adsorbent obtained from raw barl
24 In addition, site energy distribution of the pretreated barley straw for levofloxacin adsorption was
25 tivities of the ethanolic extracts from both pretreated beans and the control were 1.3-1.6 times high
26 red the effect of arginine on pH dynamics by pretreating biofilms with 75 mM arginine, followed by th
29 g site just before i.v. injection of IgM/LPS-pretreated BMDC or using IL-10 knockout BMDC fails to in
30 on and demonstrated that 0.5 x 10(6) IgM/LPS-pretreated BMDC, when injected into wild-type C57BL/6 mi
32 ltiple pulse amperometry with a cathodically pretreated boron-doped diamond electrode, using 0.30molL
35 250 to 550 degrees C when bamboo biomass is pretreated by iron-sulfate-clay slurries (iron-clay bioc
37 of (111)In-DOTA-IA in the area of VX2 tumors pretreated by pHIFU compared with the control VX2 tumors
38 ic delivery of (111)In-DOTA-IA in VX2 tumors pretreated by pHIFU compared with the control VX2 tumors
39 mpared with the control VX2 tumors not being pretreated by pHIFU, and statistical analysis revealed a
42 of C5l2 in oxidized low-density lipoprotein-pretreated C5a-induced cytokine expression, as measured
43 ofile and is active in patients with heavily pretreated ccRCC, validating direct HIF-2alpha antagonis
45 cells with a CD38 inhibitor and 2) increased pretreating CD56(bright)CD16(-) NK cells with a nucleosi
46 expressions in HSC-T6 were suppressed in Flu-pretreated cells compared to those without pretreatment.
47 wever, ExoN(-) virus generated from IFN-beta-pretreated cells had reduced specific infectivity and de
52 (PUFAs) at the bis-allylic position; indeed, pretreating cells with PUFAs containing the heavy hydrog
58 up to 86 gL(-1) Then, optimizing SSF of CELF-pretreated corn stover achieved unprecedented ethanol ti
60 ression of T cell proliferation by CDDO-DFPA pretreated DCs, which failed to passively induce EAE.
62 developing P. falciparum ring stages and DHA-pretreated dormant rings (DP-rings) using a panel of ant
67 ted by electrochemical analysis of pyocyanin-pretreated Fap fibrils subjected to the same washing pro
68 ment of these conditions, we discovered that pretreating FGE with copper(II) is required for high tur
70 of color composition between the control and pretreated freshly fermented model wines were not relate
71 s and batch reactor experiments with sulfide-pretreated graphite powder were used to differentiate th
74 und model, we found the effects of succinate-pretreated hMSC enhanced wound closure, vascularization
75 from mice injected with saline and in medium-pretreated human monocytes, THP-1, and MonoMac-6 cells,
76 comes relative to lapatinib alone in heavily pretreated, human epidermal growth factor receptor 2-pos
77 active in the extracellular compartment, we pretreated IL-37 transgenic mice with IL-37-neutralizing
79 Through the production of IL-10, alphaGalCer-pretreated iNKT cells impaired antitumor responses and r
80 talyzed pro-EGF1020-1027 peptidolysis, while pretreating intact platelets with PAD4 suppressed ADAMDE
81 or Salmonella colitis, we infected kanamycin-pretreated interleukin 8R (IL-8R) mutant mice and contro
83 1-KO, HIF-1alpha-KO mice, and wild-type mice pretreated intracolonically with locked nucleic acid ant
84 eritoneal dose of antigen in sensitized mice pretreated intraperitoneally with anti-S1P, isotype cont
88 wall constituents during saccharification of pretreated lignocellulose, particularly in relation to r
93 ed hemophagocytosis in resting and IFN-gamma-pretreated macrophages, whereas lipoteichoic acid and sy
95 e of the tested TCRs consistently recognized pretreated MC2(+) cell lines from melanoma, head and nec
96 ingle-arm multicenter trial in patients with pretreated metastatic NSCLC who received either 8 or 10
97 olled adult patients (aged >/=18 years) with pretreated metastatic stage IV BRAF(V600E)-mutant NSCLC
98 ized and applied in an adsorption column, to pretreat methylene blue (MB) wastewater with high concen
102 ntreated conventional mice, but not from Abx-pretreated mice, enhanced the ability of APCs to prime a
106 e-escalation phase, 25 patients with heavily pretreated MM (22) or Waldenstrom macroglobulinemia (3)
107 tion with dexamethasone is active in heavily pretreated MM and propose a RP2D of 45 mg/m(2) (80 mg) p
109 marked single agent activity in extensively pretreated MM, and preliminary results from studies with
111 nnate and adaptive immunity, even in heavily pretreated multiple myeloma, which correlates with clini
112 ermented model wine obtained from PEF and TV pretreated musts being the most different with an increa
115 1 mg/kg MEK1/2 inhibitor given to TNF-alpha-pretreated nude mice after human SSRBC infusion and onse
116 1, or 2 mg/kg MEK1/2 inhibitor to TNF-alpha-pretreated nude mice before human SSRBC infusion inhibit
118 een liver transplant recipients who were not pretreated or pretreated and failed to downstage compare
122 rall survival in these patients with heavily pretreated ovarian cancer; no dose-limiting toxicity was
123 ent induced favorable responses in a heavily pretreated patient cohort, justifying further studies.
124 ts with relapsed/refractory DLBCL, a heavily pretreated patient population with a high unmet medical
127 r venetoclax failure, we analyzed 67 heavily pretreated patients on 3 early phase clinical trials.
128 n both ALK inhibitor-naive and ALK inhibitor-pretreated patients who had progressed after chemotherap
131 mokine receptor 4 monoclonal antibody, in 41 pretreated patients with cutaneous T-cell lymphoma.
132 e the first-in-human experience in 3 heavily pretreated patients with intramedullary and extensive ex
133 profile and therapeutic activity in heavily pretreated patients with metastatic colorectal cancer, a
136 bstantial efficacy as monotherapy in heavily pretreated patients with multiple myeloma, as well as in
137 duration of response 10.4 months) in heavily pretreated patients with mycosis fungoides (MF) and Seza
138 exhibited antitumor activity in extensively pretreated patients with relapsed or refractory B- and T
139 le, is an active salvage regimen for heavily pretreated patients with relapsed or refractory Hodgkin'
140 tuximab vedotin plus bendamustine in heavily pretreated patients with relapsed or refractory Hodgkin'
143 sociated with durable responses, and safe in pretreated patients with Waldenstrom's macroglobulinemia
144 ositive patients, including seven crizotinib-pretreated patients, an objective response was achieved
151 (in 14%), which were more common in heavily pretreated patients; postprocedural bleeding (in 3%); ep
154 /L CORM-401 (or inactive compound iCORM-401)-pretreated PMN for 5 minutes in the presence of 1.0 dyn/
159 s upregulated in the NAc and mPFC of cocaine-pretreated rats after cocaine-primed reinstatement, and
163 nd-line treatment for patients with platinum-pretreated recurrent or metastatic squamous cell carcino
164 nd has high single agent activity in heavily pretreated relapsed and refractory multiple myeloma (MM)
165 Treatment options for patients with heavily pretreated relapsed and/or refractory multiple myeloma r
166 e-escalation study, 28 patients with heavily pretreated relapsed or refractory Hodgkin lymphoma recei
168 , counter regulation analysis of TLR2 ligand pretreated retina or the use of retinas from TLR2 knocko
169 uch substrates and to ferment hydrothermally pretreated rice straw under simultaneous saccharificatio
170 reatment choice for patients who had heavily pretreated, rituximab-refractory Waldenstrom's macroglob
171 reatment choice for patients who had heavily pretreated, rituximab-refractory Waldenstrom's macroglob
173 traction of artificial dyes was developed to pretreat samples in order to extract most of the artific
175 ubation arm AK clearance for the microneedle pretreated side was 43% compared with 38% on the sham si
176 skin reactions were most intensified in AFXL-pretreated skin and correlated with PPIX fluorescence an
177 e was 2.5 times higher than with dilute acid-pretreated solid and 13.8 times higher than with untreat
178 mpared to 24-h storage ( P < 0.05), with EDC pretreated specimens exhibiting significantly lower acti
180 egradation mechanism of CelA on a variety of pretreated substrates to better understand how the diffe
181 prevented when mice were administered FKGK18-pretreated T cells or when FKGK18 administration was ini
185 H sensor utilizes GSPEs which are chemically pretreated to form surface immobilized oxygenated specie
188 s significantly higher than that in non-CA4P-pretreated tumors at both 1 hour (P < .03) and 24 hours
189 ed community analysis that providing amylase-pretreated wheat bran as the sole added energy source to
191 dHc with AAV-Cre, and in NBQX- and rapamycin-pretreated wild-type mice, these compounds blocking alph
192 reas slow hydrolysis occurred when they were pretreated with 1 g L(-1) urea (14-35% hydrolysis after
193 with primary human T cells, epithelial cells pretreated with 1,25D suppressed activation of CD4(+) an
194 synthetic human urine when the bacteria were pretreated with 10 g L(-1) urea, whereas slow hydrolysis
198 ned suppressed after reinfusion of platelets pretreated with a P2Y(1) antagonist or a Rho-associated
203 rescence reached highest intensities in skin pretreated with AFXL (median, 8661 arbitrary units [AU])
207 d peripheral blood mononuclear cells (PBMCs) pretreated with anti-HLA antibody+ sera (in vitro ADCC),
209 s on AMs were diminished when the MDSCs were pretreated with anti-PD-L1 antibody, suggesting that MDS
212 lpha2 adrenoceptors was demonstrated in rats pretreated with atipamezole, an alpha2 adrenoceptor anta
213 ed phase shifts are blocked when animals are pretreated with atropine injections to the SCN, demonstr
214 rate of cellulose hydrolysis for switchgrass pretreated with biomass-derived ILs was slightly slower
217 erapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin.
221 ymphoma cells with distinct surface antigens pretreated with different bispecific streptavidin-scFv f
222 ectively, by liver microsomes from male rats pretreated with different inducers; untreated male monke
223 ence signal was detected when specimens were pretreated with EDC compared to controls ( P < 0.05).
225 ogical tests after MPTP intoxication in mice pretreated with either VIPR1 or VIPR2 agonist or after a
226 atients with advanced breast cancer who were pretreated with endocrine therapy and mTOR inhibitors.
227 ory to assay invasion of target erythrocytes pretreated with enzymes affecting receptor subsets.
229 differentiated into mesenchymal cells (MC), pretreated with excess free sterols, Lovastatin, or etha
233 ndard chart after 5 to 12 weeks for children pretreated with glasses (2 RCTs, 240 participants); more
234 olate (FA)-labeled human serum albumin (HSA) pretreated with glutathione (GSH) based on the low pH- a
235 ntial neuroprotective property, neurons were pretreated with GM1 for 24 h prior to glutamate exposure
236 Huh7 and PLC5) and an ectopic xenograft were pretreated with HDAC inhibitor or short hairpin RNA to k
238 tion of unprotected 1,6-anhydroglucose (10), pretreated with i-Bu2AlH, i-Bu3Al, Et3Al, Me3Al, or n-oc
239 lammation were assessed in anesthetized rats pretreated with IH-1 (2 min hypoxia, 2 min normoxia; 8 h
242 and survival in vitro Furthermore, mouse SCs pretreated with Inh X migrate extensively in the demyeli
243 drops in oxygen after hepatectomy, mice were pretreated with inositol trispyrophosphate (ITPP), an al
246 als and nonsevere and severe asthmatics were pretreated with JQ1/SGCBD01 and I-BET762 prior to stimul
250 receptor activation run down when cells are pretreated with Li(+), an inhibitor of inositol monophos
255 re the SERS substrate, SMP sheets were first pretreated with n-octylamine for effective decoration wi
256 uorescence levels were demonstrated for skin pretreated with non-AFXL (median, 2898 AU), methyl amino
260 incidence of DGF was similar between donors pretreated with or without NAC (39/118; 33% vs. 30/118;
262 ternalized LL-37 was detected in macrophages pretreated with P2X7R antagonists or, more specifically,
264 nt potentiation was also observed in neurons pretreated with pertussis toxin, an uncoupler of G prote
266 ting the left carotid artery, and VSMCs were pretreated with platelet-derived growth factor (PDGF)-BB
273 cultures of (i) intact human skin, (ii) skin pretreated with tape-strippings and (iii) skin pre-expos
275 vehicle-treated whereas the other half were pretreated with the A2A receptor-selective antagonist KW
277 ation and this effect was blocked in animals pretreated with the GLP-1 receptor antagonist exendin-(9
278 s were introduced into protoplasts that were pretreated with the glycopeptide antibiotic phleomycin,
279 erved in Thp-1-derived macrophages that were pretreated with the GSK3alpha/beta inhibitor CT99021.
282 center, each liver graft of this center was pretreated with the new machine perfusion "Hypothermic O
285 e NMDAR activity in brain slices of WKY rats pretreated with the protein phosphatase 1/2A, calcineuri
286 ne reporter assays, showing that Fap fibrils pretreated with the QS molecules activate the reporters
287 ow-mediated dilation was measured in vessels pretreated with the telomerase inhibitor BIBR-1532 or ve
289 on of murine and human HSPCs, which had been pretreated with treprostinil and forskolin, enhanced sur
295 posure in different groups of rats that were pretreated with vehicle solution, a PAC1 receptor antago
297 s in neurons, effects that can be reduced by pretreating with a microtubule stabilizer, an antioxidan
298 tivity by introducing the mutation K1250A or pretreating with the CFTR potentiator VX-770 (Ivacaftor)
300 ndent osteogenesis on rigid substrates, with pretreated xenografts calcifying in vivo to a similar ex
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