ライフサイエンスコーパス: previously characterized

1 Its function in these cells has not been previously characterized.

2 nscriptional activation by CtBP has not been previously characterized.

3 onemal accessory complex, but only ODA5p was previously characterized.

4 ring oxytetracycline 1 biosynthesis has been previously characterized.

5 core alpha1,6-fucosyltransferase FUT-8) were previously characterized.

6 d antimicrobial benzo[c]phenanthridines were previously characterized.

7 individual activation dynamics have not been previously characterized.

8 nto the discovery of CO2 -fixing enzymes not previously characterized.

9 mary endosymbiont), Sodalis and Wolbachia as previously characterized.

10 action mechanism involves protonation of the previously characterized 1,2-mu peroxy Fe(III)Fe(III) (P

11 ae that were serologically distinct from the previously characterized 15 serovars were described, and

12 In the presence of antagonists for the previously characterized 5-HT(1A) and 5-HT(2) receptors,

13 ng an observational meta-analysis design, we previously characterized a gain-of-function microRNA-410

14 We previously characterized a Galpha12-specific signaling p

15 ode a human IgA1 protease gene, igaA, and we previously characterized a novel human IgA1 protease gen

16 We have previously characterized a panel of anti-TG2 mAbs genera

17 We have previously characterized a population of Trm cells that

18 We previously characterized a recombinant neprilysin that c

19 We previously characterized a system in which revertant col

20 We have previously characterized a trisomy 7 cell line (1CT+7) s

21 e chronic constriction injury pain model) of previously characterized A3AR agonist, 2-(3,4-difluoroph

22 In contrast to most previously characterized accuracy modulators, including

23 l adhesion (FA) system that is distinct from previously characterized actin/FA structures.

24 A in GLUT4 trafficking is independent of its previously characterized activity in ER exit site format

25 Hp0267 shares no sequence homology with previously characterized ADDs, yet both are members of t

26 In the latter experiment, previously characterized adducts, both expected and unex

27 rdingly, ouchless mutants fail to complement previously characterized adgra2 mutants and exhibit high

28 ation of AgOr transcript abundance data with previously characterized AgOr excitatory odorant respons

29 he enzyme was purified and identified as the previously characterized alanine dehydrogenase.

30 Cross-comparison of AmbO5 with a previously characterized aliphatic halogenase homolog We

31 Previously characterized ALK, NTRK1, and PAX3 fusions we

32 he new isomer and the E configuration in all previously characterized allene oxides.

33 onserved surface on GS that is distinct from previously characterized allosteric and binding surfaces

34 We previously characterized alpha-helical cytotoxic islet a

35 hitecture and assembly mechanism relative to previously characterized AMA-RON2 complexes.

36 4), as a novel amyloidogenic protein with no previously characterized amyloid-prone domains.

37 tified three thorax-specific neuroblasts not previously characterized and show that HOX genes confine

38 ctrical activity of these cells has not been previously characterized, and it is not known whether al

39 s using these antibodies, in addition to the previously characterized anti-tau oligomer antibody T22.

40 he transgenic lines described here and those previously characterized appear to result from different

41 ressed sequence tag databases, including the previously characterized apple (E,E)-alpha-farnesene syn

42 We previously characterized Arabidopsis thaliana mutants wi

43 study shows that Drosophila KDM4A (dKDM4A), previously characterized as a euchromatic histone H3 K36

44 it heterozygous (gamma2(+/-)) mice, which we previously characterized as a model animal with construc

45 Although BAK1 was previously characterized as a negative regulator of cell

46 Here, we find that Xenopus Wave1, previously characterized as a protein involved in actin

47 , we identify the dleu2/mir15a/16-1 cluster, previously characterized as a regulator of B-cell prolif

48 The s1pr2 gene was previously characterized as a regulator of cell migratio

49 Here we show that the Dos1/2-Cdc20 complex, previously characterized as a silencing complex essentia

50 It was previously characterized as an endoribonuclease with pre

51 The hypothesis was that isolates that were previously characterized as contagious would be identifi

52 s and mice, an NMDAR-independent form of LTP previously characterized as dependent on voltage-gated C

53 zen archived pediatric respiratory specimens previously characterized as either negative or positive

54 d proteins from the D. reducens proteome not previously characterized as iron reductases.

55 strate that mGlu1 receptors, which have been previously characterized as oncogenes, also behave like

56 ive functions, and these cells have not been previously characterized as part of the response to UVB.

57 NtEXO70A1a localized to the small area previously characterized as the site of exocytosis in th

58 es quick screening of IAA conjugates in both previously characterized as well as uncharacterized spec

59 In previously characterized ASD risk loci, we identified 49

60 In contrast with previously characterized AurA activators, NPM does not t

61 Previously characterized B(-) mutants blocked assembly b

62 pecificity for Tyr over Phe as compared with previously characterized bacterial enzymes, consistent w

63 is homologous in structure and activity to a previously characterized bacterial thiaminase I.

64 identified based on sequence similarity to a previously characterized binding site for HetR in the pr

65 The enzyme has been previously characterized biochemically in fungi, but no

66 bacteriological medium were mediated by the previously characterized biofilm factors poly-N-acetyl g

67 adhesion molecule-1, and leptin, as well as previously characterized biomarkers, including neuron-sp

68 o 100-fold higher neutralizing activity than previously characterized bnMAbs.

69 All previously characterized broadly neutralizing antibodies

70 lates that had FKS1 HS1 and FKS2 HS1 domains previously characterized by DNA sequencing.

71 When applied to 312 P. acnes isolates previously characterized by MLST and representing types

72 cal environment of the Ppant arm of two ACPs previously characterized by solution NMR, and was used t

73 al propagation in nanomagnet chains has been previously characterized by static magnetic imaging expe

74 was undertaken in a large cohort of 43 cases previously characterized by targeted next-generation seq

75 y P. aeruginosa and 30 A. baumannii isolates previously characterized by whole-genome sequencing from

76 treme N terminus of Psd2p (C2-1) as well the previously characterized C2 domain of Psd2p (C2-2).

77 tational framework improves the detection of previously characterized cell-cycle genes compared to ap

78 ts of 145 (for HPeV, n = 70; for EV, n = 75) previously characterized cerebrospinal fluid (CSF) speci

79 cificity of the technology for detecting all previously characterized changes (mutations and benign S

80 ded paratope that differs significantly from previously characterized Chlamydiaceae-specific mAbs des

81 ns of conserved RNA structure, including all previously characterized cis-acting regulatory elements

82 CKAMP52 and CKAMP59-that, together with the previously characterized CKAMP44, constitute a novel fam

83 te selective connections of these cells with previously characterized components of the circuit.

84 d compare the activity of these compounds to previously characterized compounds that act at the PAR1

85 vivo through genetic knockdowns, the use of previously characterized compounds with high affinity fo

86 A therapeutic vaccine platform that has been previously characterized consists of heat-killed recombi

87 educed Gd-MoFeP is structurally identical to previously characterized counterparts around the FeMo-co

88 of approximately 240 pN, well below that of previously characterized covalent mechanophores.

89 CP-overexpression (OX) cells compared with a previously characterized cp-knockdown line.

90 gulation are common elements shared with the previously characterized CsLycB2a promoter, and these sh

91 ensitivity of RNA binding is correlated with previously characterized CyPA dependence or CsA sensitiv

92 combined with mRNA expression profiling and previously characterized data on a large set of kinase i

93 The structure also reveals that previously characterized Dbf4 mutants with checkpoint ph

94 ment, caused considerable production of some previously characterized DBPs in addition to novel bromi

95 Ace2/Swi5 paralogs, they are associated with previously characterized differences in posttranslationa

96 Here, we use a previously characterized dimerization system to study en

97 Previously characterized disease-causing mutations in IG

98 in the regulatory region of MYOD1, including previously characterized distal regulatory regions (DRR)

99 Ag that was significantly more potent than a previously characterized dNKT cell Ag, mammalian phospha

100 in maize resistance to SCMV, differing from previously characterized dominant or recessive potyvirus

101 We demonstrate on four previously characterized drug effect data sets that appl

102 ired for the hallmark inflammatory responses previously characterized during murine vaginitis.

103 r run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (B

104 se mutants were used to further define three previously characterized E. coli DCS-resistant strains (

105 ehaved differently from one another and from previously characterized (early deletional) responses of

106 We compared these with previously characterized EAST/SeSAME mutants (G77R and A

107 Unlike previously characterized EGFR variants, mLEEK lacks the

108 We have previously characterized eIF4E1b as a component of the C

109 We have previously characterized electrophysiological properties

110 We find that this cluster as well as the previously characterized endocrocin (enc) cluster both c

111 fication systems, in addition to those using previously characterized enzymes such as Dam, Dcm, TET/J

112 It had a similar K(m) and V(max) to previously characterized enzymes using sucrose as a subs

113 BIS1 acted in a complementary manner to the previously characterized ethylene response factor Octade

114 GREVE makes use of previously characterized events to identify such regions

115 ncluding mature tissues, where expression of previously characterized Exo70 genes is usually absent.

116 cal and molecular findings are separate from previously characterized FGFR2 disorders and represent a

117 both monooxygenases are distinct from those previously characterized for DMNT and TMTT synthesis in

118 restorative mutations (I34N, Q42K, and H87Y) previously characterized for their role in protein struc

119 downstream Homeobox network and other genes previously characterized for their role in tumorigenesis

120 Three Cee homologues previously characterized from other bacteria (IroE, IroD

121 rrelation with ZPA- and AER-expressed genes, previously characterized functional ZPA and AER enhancer

122 t its properties closely resemble those of a previously characterized fungal homolog, afTMEM16.

123 ochemical properties similar to those of the previously characterized fungal serine protease inhibito

124 ms in disease progression in addition to the previously characterized fusobacteria, proteobacteria, f

125 ts phylogenetic relationships with the other previously characterized GALVs.

126 Also, the previously characterized gene clusters escaping XCI in h

127 suppressor of cdc thirteen) is encoded by a previously characterized gene, MERISTEM DISORGANIZATION1

128 candidate selected regions that include both previously characterized genes (e.g., transcription elon

129 eing differentially regulated, including the previously characterized glucose and xylose transporter

130 glyoxalases that are not redundant with the previously characterized glutathione-dependent GLO1/GLO2

131 In contrast to previously characterized glycan-dependent bNAbs that rec

132 We previously characterized HAIYPRH, from the M13-based Ph.

133 f aptamer-conjugated PSi biosensors, where a previously characterized his-tag binding aptamer (6H7) i

134 complexes: NAP-1, NLP, and nucleophosmin are previously characterized histone chaperones, and TAP/p32

135 kinetics of the PfSET7 enzyme are similar to previously characterized histone methyltransferase enzym

136 acteristics of the accessions disclosed both previously characterized (HMA4, HMA3) and new candidate

137 In contrast to previously characterized homologs, both of these protein

138 We have previously characterized HTLV-3- and HTLV-4-encoded anti

139 identified PRAT proteins is identical with a previously characterized hypothetical protein (HP) of 20

140 tes are observed, the second of which is the previously characterized I(core) millisecond intermediat

141 at IGMT5, a gene with moderate similarity to previously characterized IGMTs, encodes the methyltransf

142 Here, we examined the role of previously characterized IGR IRES mutations on viral yie

143 exhibited a metabolic burden similar to that previously characterized in aneuploid yeast and cultured

144 tor-1 (TCF1, encoded by Tcf7), a protein not previously characterized in beta cells.

145 h they are relatively rare, niches have been previously characterized in both the brain and spinal co

146 that an allosteric site, the "minor pocket," previously characterized in CXC chemokine receptors-1 an

147 location within a putative repressor region previously characterized in mice, and its disruption of

148 les of dynamic polymerase exchange have been previously characterized in model systems provided by co

149 The polymers used were previously characterized in moisture content, ash and ni

150 nk the acetylome to the circadian metabolome previously characterized in our laboratory.

151 manner consistent with a pull-push mechanism previously characterized in pyramidal cells.

152 reaction and proliferation of RPE cells than previously characterized in rodent studies.

153 These include events previously characterized in the context of myotonic dyst

154 The seven-step pathway of MI degradation was previously characterized in various soil bacteria includ

155 l (7DHC) metabolism initiated by CYP11A1 and previously characterized in vitro, occur in vivo, we ana

156 -repeat transposable element (MITE) families previously characterized in wheat that together account

157 appeared parallel at the molecular level to previously characterized incompatibilities, but also rai

158 atis that has evolved independently from the previously characterized interaction between bacterial t

159 domains forming the channel pore, as well as previously characterized interaction sites for other sma

160 In addition to the previously characterized interaction with replication pr

161 Validation of SynAg with 89 previously characterized interactions shows a log-linear

162 This set of putative PPIs included both previously characterized interactors, along with a large

163 31)P NMR spectroscopy and by comparison with previously characterized intermediates observed in the p

164 ribed S. aureus genotype B was present among previously characterized isolates from cases of bovine i

165 kinase ribozyme K28(1-77)C, in contrast with previously characterized kinase ribozymes, requires Cu(2

166 ntly less affected in Gnaq(d/d) mice than in previously characterized Kiss1r(-/-) or Kiss1r(d/d) mice

167 The previously characterized L407F mutant allele of Arabidop

168 tnatal mortality, are uniquely distinct from previously characterized lipodystrophic mouse models.

169 gnals, including three rare variants, at two previously characterized loci: FGB and IRF1.

170 We tested the ability of previously characterized Long QT Syndrome hERG1 mutation

171 Remarkably, and in contrast to all previously characterized LPMOs, which are active only on

172 This method distinguished previously characterized lung- and liver- targeting nano

173 lysis), a conservation not observed in other previously characterized lytic transglycosylase families

174 The proper expression of two previously characterized MATE flavonoid transporters MtM

175 we have expanded the defects associated with previously characterized matrix-mislocalized-mutant tafa

176 The peptide backbone is distinct from all previously characterized Mbns, and the post-translationa

177 gs to the amidohydrolase superfamily, unlike previously characterized MCP hydrolases, which are serin

178 In addition to the previously characterized mechanism of action of CX-5461

179 vidence to suggest that hPolbeta follows the previously characterized mechanisms of D-stereoselectivi

180 site does not bear close resemblance to any previously characterized member of its superfamily, the

181 lavulanate interactions among a group of 101 previously characterized members of the Enterobacteriace

182 y of the pSHP2-expressing cell population to previously characterized meristematic domains, further s

183 mplement largely resembled the activity of a previously characterized metalloproteinase of T. forsyth

184 Unlike previously characterized MIA-producing plants, C. acumin

185 The newly sequenced genomes are similar to previously characterized millipede sequences in terms of

186 lay mixed mechanisms of action compared with previously characterized modulators of other mAChRs.

187 Previously characterized monoclonal antibodies that bloc

188 with either m1C3 or m4B7 were inserted into previously-characterized mosquito chromosomal "docking"

189 We have previously characterized mouse CMV (MCMV)-encoded immune

190 measuring thrombus contraction in vivo and a previously characterized mouse line with a defect in int

191 ck in mouse cells is not attributable to the previously characterized mouse restriction factor Fv1.

192 icity (LTD/LTP), setting it apart from other previously characterized MPEP site PAMs.

193 We previously characterized multiple mouse monoclonal antib

194 Unlike the previously characterized Muscleblind (Mbl) circular RNA,

195 A previously characterized mutant, Gp59-I87A, exhibits mar

196 formation of amyloidogenic fragments in the previously characterized mutants.

197 We have previously characterized mutations in a Caenorhabditis e

198 ssessing the effect of expression levels and previously characterized mutations on BAR.

199 Their diversity and similarities with previously characterized natural killer (NK) cells and l

200 .2 genes encoding the NDUFS8 subunit and the previously characterized ndufs4 CI mutant.

201 served YXXXY motif that is used by all other previously characterized NEAT domains to coordinate iron

202 In contrast, all previously characterized neutralizing anti-gD MAbs block

203 nd to be regulated by NF addition, including previously characterized NF-induced marker genes.

204 sponsible for SPI-1 repression have not been previously characterized, nor have the bacterial signali

205 arities and is only distantly related to all previously characterized NTTs.

206 the number of known off-targets for certain previously characterized nucleases more than tenfold.

207 lex" that is heterogeneously formed from our previously characterized Nup54.Nup58 and Nup54.Nup62 int

208 ted high specificity by detecting NV only in previously characterized NV-positive stool samples in co

209 : nonamer (9mer), dodecamer (12mer), and the previously characterized octadecamer (18mer).

210 s of this transition, but in contrast to the previously characterized oligogenic basis of a pollinato

211 We have previously characterized one such system: the EphA2:SHIP

212 induction, distinguishing MG_427 from other previously characterized osmC genes.

213 operate through a different pathway from the previously characterized OXI1-dependent response to path

214 A previously characterized paralog, SYM-1, is also express

215 e wild type level of PAS susceptibility in a previously characterized PAS resistant strain of M. tube

216 Finally, we found that 2 previously characterized patients with SOX2 haploinsuffi

217 and function of PDZ2as, in comparison to the previously characterized PDZ2 domain.

218 The proteinase K LFH <3 kDa and a previously characterized pepsin LFH <3 kDa with ACE-inhi

219 dipeptide product shows that, compared with previously characterized peptidoglycan amidases, the enz

220 rogen bond with phosphate that is typical of previously characterized phosphate-binding proteins, but

221 e A (PKA) or phospho-mimetic mutation of the previously characterized PKA site, Ser-499, were suffici

222 Progeny from a cross between hms-1 and the previously characterized PME inhibitor5 overexpression l

223 Although there are similarities with previously characterized poliovirus polymerase fibrils,

224 particles that have largely been stripped of previously characterized pre-40S components, but retain

225 These cells, which can be distinguished from previously characterized precursors in the myeloid linea

226 reactive descending neurons are identical to previously characterized primary commissure pioneer (PNP

227 iptional start sites (TSS) and is defined by previously characterized promoter-associated chromatin m

228 extension shows no structural similarity to previously characterized protease propeptides and instea

229 three showed no substantial homology to any previously characterized protein in the NCBI database.

230 earches failed to reveal similarities to any previously characterized protein or domain.

231 Unlike previously characterized protein tyrosine phosphatases (

232 gous RF barrier is distinct from a number of previously characterized, protein-mediated, RF pause sit

233 Most previously characterized proteins that are required for

234 Moreover, mph2-and previously characterized PSII repair-defective mutants-e

235 We previously characterized rapid dynein-dependent lytic gr

236 By positional cloning using a previously characterized rat strain with altered titin m

237 In addition to recapitulating previously characterized regulons, we discovered 454 nov

238 ptococcus pyogenes, SEER identifies relevant previously characterized resistance determinants for sev

239 nstrated among Rtn4, Ceg9, and atlastin 1, a previously characterized reticulon interacting partner.

240 We conclude that dKDM4A, in addition to its previously characterized role in euchromatin, utilizes b

241 ate this function to be independent of their previously characterized role in the DNA damage response

242 ires the alpha7 tail binding site, besides a previously characterized Rpt5 binding site.

243 mple sequencing data from varying numbers of previously characterized samples at varying depths of co

244 Among 270 additional previously characterized samples, both multiplex panels

245 Here we use 20 previously characterized Sanger-sequenced positive contr

246 represents a novel fold that is unrelated to previously characterized secretion chaperones.

247 lar basis of these effects, mutation of four previously characterized serines within the Kv3.4 N-term

248 HIV and Treponema pallidum antibodies in 450 previously characterized serum specimens.

249 looked for somatic mutations by identifying previously characterized single-nucleotide variants and

250 We previously characterized SLC, a stem-loop structure in t

251 variants in the current study, as well as in previously characterized species A and J viruses infecti

252 ding protein different in structure from all previously characterized ssDNA binding proteins.

253 m is subject to dual regulation and that the previously characterized stimulation by acidic phospholi

254 Mice were infected with the previously characterized straight-rod Deltapgp1 and Delt

255 of the other serotypes, which have not been previously characterized: [structure: see text] Common a

256 In contrast to these previously characterized structures, the F. novicida tub

257 Abeta antibody binding sites, distinct from previously characterized structures.

258 Myroicolsin displays low identity (<30%) to previously characterized subtilisin-like proteases, and

259 We have previously characterized such a determinant, employing t

260 seemingly late-acting defect was rescued by previously characterized suppressors of early, preprocap

261 times, making them unique and distinct from previously characterized symbioses, where multiple micro

262 M2-A1-N1-T1-E2-H3), the same as those of the previously characterized symptomatic N155 Vellore isolat

263 We recover TS/CYP gene pairs for previously characterized terpene metabolic gene clusters

264 gnizing group 2 influenza A viruses has been previously characterized that binds to a highly conserve

265 Using atomic force microscopy, we previously characterized the disruption of model membran

266 We previously characterized the Enpp1(asj) mutant mouse as

267 We have previously characterized the interactions of the respons

268 We previously characterized the link between WNT7A and the

269 We previously characterized the Mdr2(Abcb4)(-/-) mouse as a

270 We previously characterized the TRN-SR2 binding interface i

271 We previously characterized the VRC01 class of antibodies,

272 We have previously characterized three monodomain ARO/CYCs: ZhuI

273 Bacterial isolates previously characterized through whole-genome sequencing

274 ive-fold lower Michaelis Constant (Km ) than previously characterized TNT-active Arabidopsis thaliana

275 ted cells also upregulated several genes not previously characterized to be antiviral, such as RND1,

276 e that distinguishes SusC-like proteins from previously characterized TonB-dependent transporters.

277 at 10-fold lower concentrations than related previously characterized translation blockers.

278 achomatis genomes, led us to re-evaluate the previously characterized transport properties of Npt1(Ct

279 A previously characterized triplex DNA-specific antibody (

280 Previously characterized trisolvated dimeric enolates un

281 +) fluorescence responses, compared with the previously characterized (TRPC3b) isoform when activated

282 We previously characterized two Azotobacter type III PKSs (

283 We have previously characterized two EHDs (EH domain containing

284 We have previously characterized two SNARE proteins, secretory p

285 We previously characterized two tau strains that stably mai

286 Previously characterized Type I systems use two identica

287 n assays revealed that H2A.Z was enriched at previously characterized u-PAR-regulatory regions (promo

288 induced neutrophil transepithelial migration previously characterized using cell line-based models.

289 ty, we compared V. splendidus 13B01 with the previously characterized V. splendidus 12B01, which has

290 mens, and found that they clustered with two previously characterized Vibrio navarrensis isolates in

291 Compared to previously characterized viruses expressing amino-termin

292 wed patterns of connectivity consistent with previously characterized visual system connections, and

293 In this instance and in contrast to the previously characterized visual system, endocytosis from

294 We used wild-type VP35 and previously characterized VP35 mutants to clarify VP35-DC

295 ng at frq functions in a parallel pathway to previously characterized VVD-dependent silencing and is

296 Unlike previously characterized wHTH proteins, PCG2-DBD utilize

297 nsferase GCN5 ((Gcn5(hat/hat) )), which were previously characterized with respect to their exencepha

298 that this gene shows no redundancy with the previously characterized xyloglucan galactosyltransferas

299 The site, which is also shared with a previously characterized yeast aptamer, is close to the

300 n from diunsaturated fatty acids produced by previously characterized Z11-desaturase/conjugase MsexD2