ライフサイエンスコーパス: priapism

1 th sickle cell disease (SCD) risk developing priapism.

2 sive activation of these pathways results in priapism.

3 lation of opiorphin at a life stage prior to priapism.

4 molecular mechanisms for penile fibrosis in priapism.

5 e fibrosis, a dangerous complication seen in priapism.

6 with sickle cell disease (SCD), 40% display priapism.

7 dysregulation is a fundamental mechanism for priapism.

8 employed for patients with SCA and prolonged priapism.

9 ed and explored for use in the prevention of priapism.

10 , pneumonia (2), portal vein thrombosis (1), priapism (1), hemolytic uremic syndrome (1), diaphragm p

11 Priapism, abnormally prolonged penile erection in the ab

12 fibrosis in two independent animal models of priapism, adenosine deaminase (ADA)-deficient mice and S

13 Priapism, although uncommon in the general population, i

14 e molecular hallmarks and pathophysiology of priapism, an important but poorly characterized erectile

15 Disease, we assembled 273 case subjects with priapism and 979 control subjects.

16 method of choice for treatment of high-flow priapism and for restoration of penile erectile function

17 provide new insight for the pathogenesis of priapism and novel therapies for the disease.

18 atologic characteristics of individuals with priapism and SCD.

19 ide insight regarding the molecular basis of priapism and suggest that strategies to either reduce ad

20 ogical erectile signaling in mouse models of priapism and suggests novel approaches to human therapy.

21 tic sequestration, splenic sequestration, or priapism) and the acute chest syndrome, and patient-repo

22 ted with stroke, pulmonary hypertension, and priapism, and cf-PWV was associated with microalbuminuri

23 nary hypertension, cutaneous leg ulceration, priapism, and ischemic stroke.

24 e of pulmonary hypertension, leg ulceration, priapism, and risk of death in patients with sickle cell

25 ncluding pulmonary hypertension, leg ulcers, priapism, chronic kidney disease, and large-artery ische

26 Because priapism demonstrates high prevalence in patients with h

27 The optimal management of prolonged priapism for patients with sickle cell anemia (SCA) has

28 lgesics failed to produce detumescence or if priapism had lasted >4 hours, the protocol was activated

29 molecular pathophysiology of SCD-associated priapism has led to the identification of new potential

30 nd answers) on 5 urology CPGs (hematuria and priapism [HP]; staghorn calculi, infertility, and antibi

31 erections occurred in 5 percent of the men, priapism in 1 percent, penile fibrotic complications in

32 pression of genes previously associated with priapism in animal models.

33 ORA2B) signaling, we successfully attenuated priapism in both ADA(-/-) and SCD mice by restoring peni

34 e solution under local anesthesia to relieve priapism in young patients with SCA.

35 Priapism is a condition of persistent penile erection in

36 Priapism is a disorder of persistent penile erection unr

37 High-flow priapism is a rare condition characterized by a prolonge

38 Priapism is featured with prolonged and painful penile e

39 The molecular mechanism for priapism is not well characterized.

40 interesting and important, is the fact that priapism of one month's duration could well be treated b

41 her in patients who experienced skin ulcers, priapism, or renal dysfunction.

42 The 2 patients whose priapism persisted after aspiration and irrigation prese

43 that sickle cell disease mice (which show a priapism phenotype) evince dysregulated PDE5A expression

44 emergency department with a 3-day history of priapism requiring a surgically performed distal penile

45 All evaluable patients whose priapism resolved after aspiration and irrigation self-r

46 tions, we hypothesized that the mechanism of priapism rests in aberrant downstream signaling of this

47 in Mrc1(-/-)Asgr2(-/-) mice may account for priapism seen in males.

48 elocity [TRV], microalbuminuria, leg ulcers, priapism, stroke, and osteonecrosis) by clinical examina

49 Current strategies to manage priapism suffer from a poor fundamental understanding of

50 A case of delayed painless high-flow priapism that occured after blunt straddle-type perineal

51 ine accumulation in the penis contributes to priapism through increased A2BR signaling in both Ada -/

52 ent of Mrc1(-/-)Asgr2(-/-) male mice develop priapism when mating due to thrombosis of the penile vei

53 These findings suggest an association of priapism with increased hemolysis.