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1 he form of formamide (or urea in the case of primary amine).
2 fer of the acetyl group from acetyl-CoA to a primary amine.
3 analogue with C.35 hydroxyl instead of C.35 primary amine.
4 se (SSAO) catalyses oxidative deamination of primary amines.
5 e of, respectively, 2, 4, 8, and 72 equiv of primary amines.
6 enable to a variety of D-A cyclopropanes and primary amines.
7 dary amines approximately tertiary amines >> primary amines.
8 ere comparable to absorber rates for several primary amines.
9 um borohydride to reduce the nitro-groups to primary amines.
10 mulation rates in washwaters were lowest for primary amines.
11 10(8) M(-1) s(-1)), yielding ketimines, with primary amines.
12 acid permits visualization of enantiomers of primary amines.
13 (carboxylated bPEI) via carboxylation of the primary amines.
14 d but polar, hydrophobic, and variably sized primary amines.
15 as observed with both aromatic and aliphatic primary amines.
16 otodegradable monomer that can be coupled to primary amines.
17 n degree baseline separate all tested chiral primary amines.
18 id-phase synthesis starting from immobilized primary amines.
19 l of this nucleophile for the preparation of primary amines.
20 for the formation of amides from esters and primary amines.
21 ith phosphine oxide molecules than that with primary amines.
22 othiophenium ylide followed by coupling with primary amines.
23 that catalyses the oxidative deamination of primary amines.
24 e of homocysteine (Hcys) that can react with primary amines.
25 n of unactivated aliphatic C-H bonds in free primary amines.
26 ,4-b]indole-3-carboxylate, formaldehyde, and primary amines.
27 us Co-catalyzed hydrogenation of nitriles to primary amines.
28 ry hindered alpha,alpha,alpha-trisubstituted primary amines.
29 he presence of air for oxidative coupling of primary amines.
31 secondary amine piperazine (PZ) than for the primary amines 2-amino-2-methyl-1-propanol (AMP) and mon
34 rbonyl group of the Nazarov reactant and the primary amine accepts a hydrogen bond from the hydroxyl
35 drogenation reactions in the N-alkylation of primary amines, achieving good to excellent yields under
36 and Mannich conjugate additions whereby the primary amine activates the aldehyde and the catalyst ac
37 of enaminioesters from beta-keto esters and primary amines, activation of their allylic sp(3) C-H, v
40 henethylamines containing a potentially free primary amine after appropriate deprotection have been s
42 yl vinyl ether (secondary or tertiary) and a primary amine (aliphatic or aromatic) in toluene or meth
45 a multicomponent reaction of cyclohexanone, primary amine and N-tosyl-3-nitroindole followed by an o
46 We explore how two nonionic polar groups (primary amine and primary amide) influence hydrophobic i
47 th a series of linear and methyl substituted primary amines and alkanolamines have been investigated
48 deprotonated Strecker products derived from primary amines and aromatic aldehydes with 2-halobenzyl
50 component reaction between o-nitrochalcones, primary amines and beta-dicarbonyl compounds in the pres
51 ycles from alkyl dihalides (ditosylates) and primary amines and hydrazines via a simple and efficient
54 ver, these dioxabicyclic lactones react with primary amines and lysine side chains of lysozyme to for
55 t catalyze the conversion of two substrates, primary amines and molecular oxygen, to aldehydes and hy
56 Here we describe an amide formation using primary amines and potassium acyltrifluoroborates promot
57 nt protocol furnished good results with both primary amines and secondary amines and sluggish aniline
60 al organocatalyst that contains tertiary and primary amines and thiourea moieties to activate substra
61 luding hydroformylation, condensation with a primary amine, and a rearrangement step giving water as
62 ponent reaction of ninhydrin, malononitrile, primary amines, and dialkyl acetylenedicarboxylates unde
63 dropyrimidines from azirine-2-carbaldehydes, primary amines, and diazo carbonyl compounds under Rh(II
64 ining one set of 1,2-diaza-1,3-dienes (DDs), primary amines, and isothiocyanates in a different seque
65 more readily nitrosatable than the pristine primary amines, and that can form stable N-nitrosamines.
66 are formed in the photochemical oxidation of primary amines, and their reaction with (*)NO is an impo
67 3))-H oxidations of tertiary, secondary, and primary amine- and pyridine-containing molecules with tu
70 ng available and readily prepared materials, primary amines are converted to protected N(G)-aminoguan
74 Secondary amines featuring these reactive primary amines as functional groups (e.g., secondary N-m
76 the photocatalytic reaction, addition of the primary amine at room temperature or the secondary amine
77 ikely to be involved in the incorporation of primary amines at selected peptide-bound glutamine resid
78 ctivity of this catalyst for the coupling of primary amines at these loadings is made with catalysts
79 able entropic factors may be the main reason primary amine based adsorbents are more effective under
81 t identification in metabolism of a branched primary amine by a copper amine oxidase and suggests a n
82 for determining the enantiopurity of chiral primary amines by 1H NMR spectroscopic analysis is descr
83 rein is the construction of C-N bonds, using primary amines, by direct C-H functionalization with an
88 nt relative to its neutral imine tautomer in primary amine catalysts having outer-sphere silanols par
89 Direct comparison of the designed enzymes to primary amine catalysts in solution revealed a rate acce
92 and is selective for the dehydrogenation of primary amines (-CH2NH2) in the presence of amines witho
93 ist et al. using a cinchona alkaloid-derived primary amine (cinchona amine) organocatalyst, have been
94 tRAL) is directly cytotoxic and that certain primary amine compounds that transiently sequester atRAL
96 ort here the detection and quantification of primary amine-containing compounds in the original sampl
98 veloped a high-throughput method to quantify primary amine-containing metabolites in the yeast Saccha
99 by its immersion in an aqueous solution of a primary amine-containing polymer (polyallylamine (PAAm))
100 t shows pronounced enantioselectivity toward primary amine-containing racemates, separating 98% of th
103 gation in these compounds matches the single primary amine coordination of the putative active site o
106 involving condensation of an aldehyde with a primary amine, cyclization (with displacement of a halid
108 ect addressed in this article is a series of primary amines deriving from aniline having been engaged
109 of peroxisomes, such as methanol, oleate, or primary amines, determine the requirements for subsequen
110 The choice of the appropriately substituted primary amine, diamine or polyamine, allows the design o
111 ons of protonated ammonia and the protonated primary amines either in the interior or at the surface
113 to NPs, owing to its capability to label the primary amines exposed on protein surface, but also coul
114 vinylketones catalyzed by a vicinal thiourea-primary amine first reported by Tius have been explored
115 san (GC) polymer, which contains pH-titrable primary amines, followed by gadolinium complexation (GC-
116 e synthesis of aryl-, heteroaryl-, and alkyl primary amines from the corresponding boronic acids has
117 tic backbones can be achieved in which a new primary amine function represents a possible center for
118 abling feature of this chemistry is that the primary amine functionality (-CH2NHBoc) of the original
119 ydryl group may be used to conjugate MAG3 to primary amine functionalized biomolecules for the purpos
122 ation of 4-bromophthalazin-1(2H)-ones 4 with primary amines generates aminophthalazin-1(2H)-ones in g
123 h an aldehyde group and a peptide ion with a primary amine gives rise to water loss in conjunction wi
124 icarbonyls glyoxal and methylglyoxal and the primary amines glycine and methylamine have been determi
126 rine PL in the presence or in the absence of primary amine group from aminophospholipids and amino ac
127 bond is formed between a free, unprotonated, primary amine group of a lysine side chain in the peptid
128 acT, is an acetyltransferase that blocks the primary amine group of amino acids on charged tRNA molec
129 r reagents was developed that react with the primary amine group of glycerophosphoethanolamine (PE) l
130 on going from a tertiary to a secondary to a primary amine group, but that solvent insertion dominate
134 DOTA-tetraamide complexes with four appended primary amine groups are measured as a function of pH.
135 g reduction, there was sufficient amounts of primary amine groups for covalent attachment of a polyet
145 atalyze reactions of isocyanides (CN-R) with primary amines (H2N-R') and O2 to give carbodiimides (R-
147 of the enantioselective capabilities toward primary amines, however they gain broad selectivity for
148 with a covalent modification of unprotonated primary amines (i.e., N-terminus and epsilon-NH(2) of ly
149 nitrobenzene sulfonic acid (TNBS) binding to primary amines, (ii) electrophoretic migration in polyac
151 ositive modulation critically depends on the primary amine in JKJ05, which appears to interact with a
152 ent at hydrolyzing substrates that contain a primary amine in the antibiotic R-group that would be cl
153 e formation generated via reaction between a primary amine in the peptide cation and the aldehyde moi
154 to be positioned to interact with the distal primary amine in the putrescine substrate as well as the
155 s undergo hydrogenation to the corresponding primary amines in good to excellent yields under the rea
156 rides, bromides, and iodides react with many primary amines in high yields with part-per-million quan
157 rivatives can detect and identify protonated primary amines in methanol and in water, and even discri
158 r to substituted pyrroles in the presence of primary amines in protic solvent at ambient temperatures
159 tom bond formation strategy to functionalize primary amines in tandem to produce a series of valuable
160 associated with the oxidative degradation of primary amines in the absorber unit, a process known to
161 at a conjugated thiophene vinylene dyad with primary amines in the alpha,alpha'-positions could be pr
162 he side chain of arginine (Arg), and several primary amines including methylamine, ethylamine, n-prop
164 st can be replaced by commercially available primary amines, including alpha-methylbenzylamine, with
166 our disaccharide standards containing a GlcN primary amine indicated that the beta anomer of the GlcN
168 formaldehyde by in situ condensation with a primary amine into the corresponding imine in very mild
169 hylamine dehydrogenase (MADH) which converts primary amines into the corresponding aldehydes and ammo
170 Zincke reaction allows the transformation of primary amines into their respective N-alkylated or N-ar
171 74-III can be covalently functionalized with primary amine (IRMOF-74-III-CH2NH2) and used for the sel
173 ronsted acid catalyzed kinetic resolution of primary amines is described that is based on the condens
175 tones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional cal
176 (II)-catalyzed gamma-C(sp(3))-H arylation of primary amines is realized by using 2-hydroxynicotinalde
179 f alkylpyridinium salts, readily formed from primary amines, is the first example of a metal-catalyze
180 ause this assay relies on the formation of a primary amine, it could be adapted to measure the activi
181 ly, in the presence of an excess amount of a primary amine, it is demonstrated that this catalytic sy
182 tic ring with Pd(II) occurs, directed by the primary amine, leading to the formation of a palladacycl
183 aining aldehyde functionalities and selected primary amines leads to several XF-imine derivatives.
184 uble nucleophilic substitution reaction with primary amines led to the synthesis of amino-substituted
186 ivity provide hints to the potential role of primary amine ligation in pMMO: increased substrate acce
189 -C 2B 7H 13 carborane with the secondary and primary amines, Me 2NHBH 3 and ( t )BuNH 2BH 3, in ionic
191 ess, the pK(a) values of the carboxylate and primary amine moieties of 11 heparin disaccharide standa
192 metal oxide nanotubes with covalently bonded primary amine moieties on their inner wall, synthesized
193 L1)Pd(p-tolyl)](+) fragment occurred via the primary amine moiety, affording the crystallographically
194 tions identified the salt-bridge between the primary amine of 5-HT and the lipid phosphate group as t
195 atalyzes the hydroxylation of the side chain primary amine of ornithine in the initial step of the bi
196 nine, as well as reductive alkylation of the primary amine of ornithine, and each product was evaluat
198 se of substrate-assisted catalysis where the primary amine of the ampicillin R-group positions the hy
200 e, a cleavable chromogen, were conjugated to primary amines of a hydrated poly(HEMA)-based hydrogel.
202 -phosphosulfate (PAPS)] to the hydroxyls and primary amines of numerous metabolites, drugs, and xenob
207 ophilic primary amines (typically, aliphatic primary amines) often lead to quantitative reactions and
209 -iodophenylisothiocyanate, are used to label primary amines on peptides to demonstrate the scaling an
210 CuAOs) catalyze the oxidative deamination of primary amines operating through a ping-pong bi-bi mecha
211 red ring systems, by addition of a lithiated primary amine or hydrazine 5 to a dinitrile 7, 8, or 9 w
212 -3-(methylthio)acrylonitrile precursors with primary amines or amides via two key C-N bond-forming pr
214 amines, tertiary amines, sterically hindered primary amines, or amines without oxygenated groups.
216 nced enthalpic contributions associated with primary amines over secondary amines, but may be due to
217 es are shown to selectively recognize linear primary amines--over branched, secondary, and tertiary a
218 Vascular adhesion protein-1 (VAP-1) is a primary amine oxidase and a drug target for inflammatory
223 lic addition reaction of aromatic aldehydes, primary amines, propiolic acid, isocyanides, and hydrazi
224 er(III) bis(mu-oxo) complexes ligated by the primary amines, propylenediamine, and N,N,-dimethyl prop
225 etric reactions between the precatalysts and primary amines provided an important model for catalyst
228 1.0 nM to 2.6 nM, and we identified several primary amines ranging in length from C2 to C16 in Titan
231 on substitution reactions with virtually any primary amine, regional control of the substitution with
232 The catalytic hydrogenation of nitriles to primary amines represents an atom-efficient and environm
233 ategy to generate a sugar-1-phosphate, and a primary amine-requiring nucleotidylyltransferase that ge
234 vivo, likely due to the presence of multiple primary amines responsible for their polyP binding abili
235 e NO donors was examined via the reaction of primary amine, secondary amine, and amide functionalitie
236 effective N-acylating agents, reacting with primary amines, secondary amines, and sulfonamides to fo
237 beta-sultams in buffered solutions of simple primary amines shows a first-order dependence on amine c
238 Ozonation followed by chlorination of the primary amine side chain of lysine demonstrated low yiel
239 typically initiated by hydroxylation of the primary amine side chains of l-ornithine or l-lysine.
240 more important than in the absorber, but for primary amines, significant formation of total N-nitrosa
241 ylisothiourea for 1 to 2 h and the number of primary amine sites at which covalent labeling occurs is
244 ollowing advantages: it uses a wide range of primary amines, starting materials are easily available,
245 eeds via Schiff base chemistry, in which the primary amine substrate first attacks the C5 carbonyl of
246 ctions: a reductive half-reaction in which a primary amine substrate is oxidized to its corresponding
247 nd the absolute initial concentration of the primary amine substrate show that the latter parameter s
248 analogous to that observed with unprotonated primary amines such as the N-terminus or epsilon-amino g
249 ansamidations involving secondary amides and primary amines suggest that tertiary amide/secondary ami
250 ctrophiles that form adducts with thiols and primary amines, suggesting that covalent modification, r
251 entrations of LAuX in solutions containing a primary amine-terminated dendrimer leads to clear soluti
252 Proton transfer occurs only with linear primary amines, that is, when the best size and shape fi
253 Conveniently synthesized from protected primary amines, the hydrazone DGs are shown to site-sele
254 method for installation of the t2M motif on primary amines, the method described herein streamlines
255 The receptor encapsulates alkyl-substituted primary amines, then orients them toward a covalently te
256 promotes high selectivity for reactions with primary amines, thereby constraining the scope of potent
257 f the dimethyl ester derivative with various primary amines, this methodology was used to design a ra
259 n-state-derived ligands incorporate a single primary amine to interact with the catalytic aspartates
260 adducts produced from covalently attaching a primary amine to the spiroiminodihydantoin lesion, were
262 rs govern the selectivity in the addition of primary amines to alpha,beta-unsaturated aldehydes and k
263 r the click reaction family: the addition of primary amines to alpha-tertiary isocyanates (alpha-(t)N
264 dynamic kinetic resolution (DKR) to convert primary amines to amides in high yields and excellent ee
265 Here, through chemical modification of the primary amines to aromatic domains we achieved nucleic a
267 h several chiral secondary alcohols and some primary amines to evaluate their potential as chiral der
271 mine exchange followed by a cyclization with primary amines to yield fluorescent products with emissi
272 ost nonfluorescent in water, but addition of primary amines turns the fluorescence on; formation of i
277 in situ from readily available enynones and primary amines undergo thermal cyclization in diphenyl e
278 The selective hydrogenation of nitriles to primary amines using a bench-stable cobalt precatalyst u
279 es, triflates, or nonaflates with aryl/alkyl primary amines using QUINAP as the ligand provides the c
280 he direct and stereoretentive deuteration of primary amines using Ru-bMepi (bMepi = 1,3-(6'-methyl-2'
281 idases catalyze the oxidative deamination of primary amines utilizing a type(II) copper center and 2,
282 rly with a phenol or intermolecularly with a primary amine via addition-elimination reaction(s).
284 7-nitro-2,1,3-benzoxadiazole (NBD-F) labeled primary amines was monitored as a proof of concept exper
286 important enantiopure thionyl and arylalkyl primary amines were afforded by the borane-mediated enan
288 asured for the insertion of the DAC into the primary amines were consistent with an electrophilic act
289 ith optimal surface inorganic stoichiometry, primary amines were identified as "ideal" organic ligand
292 permanently blocked by iodoacetamide and the primary amines were temporarily masked with citraconic a
293 1-arylethyl amines, including a prototypical primary amine with an alpha-chiral tertiary N-alkyl grou
294 as been accomplished via the alkylation of a primary amine with the bis-triflate of a 2-substituted-1
295 ies on the specific interactions between (i) primary amine with TNT and (ii) TNT and anti-TNT aptamer
297 hat Cu promotes N-nitrosamine formation from primary amines with hydroxyl or carboxyl groups (amino a
300 treatment of mellitic acid with 3 equiv of a primary amine yields trisubstituted mellitic triimides v
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