ライフサイエンスコーパス: primary bile acid

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1 olved in the degradation of cholesterol into primary bile acids.

2 nohydroxy-cholenoic acids, and an absence of primary bile acids.

3 of the usual glycine and taurine conjugated primary bile acids.

4 ds and dipeptides decrease, whereas those of primary bile acids and sugar alcohols increase, reflecti

5 in mice prevents the synthesis of cholate, a primary bile acid, and its metabolites.

6 Primary bile acids are synthesized from cholesterol in t

7 The primary bile acids are the highest affinity endogenous l

8 thdrawal, but no effect on concentrations of primary bile acids aside from an increased accumulation

9 ine farnesoid X receptor (Fxr), which is the primary bile acid (BA) sensor, and critical regulator of

10 ression of genes involved in cholesterol and primary bile acid biosynthesis including Cyp7a1.

11 Here we report that the primary bile acid chenodeoxycholic acid (CDCA) also acts

12 d the ability of this enzyme to activate the primary bile acid, cholic acid, to its CoA derivative.

13 weight gain, and after 2 years reduced serum primary bile acid concentrations about 85%, while accoun

14 In fecal samples, levels of primary bile acids increased in the placebo group but no

15 Primary bile acid malabsorption (PBAM) is an idiopathic

16 In patients with primary bile acid malabsorption, mutations in the ileal

17 terol homeostasis and human diseases such as primary bile acid malabsorption.

18 that catalyzes conversion of cholesterol to primary bile acids) (OR, 1.11; 95% CI, 1.08-1.15; P = 8.

19 Several secondary/primary bile acid ratios were also decreased with LF in

20 The primary bile acid receptor farnesoid X receptor (FXR) ma

21 the nuclear receptor superfamily and is the primary bile acid receptor.

22 l because it can be effectively treated with primary bile acid replacement.

23 Farnesoid X receptor (FXR), the primary bile acid-sensing nuclear receptor, also plays a

24 e mouse gut after antibiotics, including the primary bile acid taurocholate for germination, and carb

25 Gut flora modify primary bile acids to produce secondary bile acids leadi

26 intestinal bioconversion of cholesterol and primary bile acids to secondary metabolites.

27 more bacterial deconjugation of taurine from primary bile acids was observed along with an increased

28 te to initiate peroxisomal beta-oxidation to primary bile acids, was confirmed by DNA analysis reveal

29 Primary bile acids were preferentially transported into

30 Primary bile acids were similar, whereas secondary bile

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