ライフサイエンスコーパス: primary immune response

1 ritical role as APCs in the induction of the primary immune response.

2 ine signal to antigen-activated B cells in a primary immune response.

3 s suggesting that B cells play a role in the primary immune response.

4 ic use (pLAIVs), but they failed to elicit a primary immune response.

5 s bacteriophage in a process that mimics the primary immune response.

6 ew that the spleen plays a minor role in the primary immune response.

7 duced retention in the bone marrow after the primary immune response.

8 l T cells that controls the magnitude of the primary immune response.

9 could predict the size and diversity of the primary immune response.

10 ng cells are replenished every 24 h during a primary immune response.

11 ons to control CD4(+) T cell fate during the primary immune response.

12 e DC apoptosis to counterbalance the nascent primary immune response.

13 ith T cells led to the induction of a potent primary immune response.

14 production that are not observed during the primary immune response.

15 ity increasing mutations by days 9-14 of the primary immune response.

16 ntly from common naive precursors during the primary immune response.

17 cells is a prerequisite for the induction of primary immune responses.

18 enting cells with a unique ability to induce primary immune responses.

19 ibuting to the generation and maintenance of primary immune responses.

20 tute a unique family of cells able to induce primary immune responses.

21 otent antigen-presenting cells that initiate primary immune responses.

22 horin 6D as a regulator of the late phase of primary immune responses.

23 tigen-presenting cells capable of initiating primary immune responses.

24 ystem and have the unique capacity to induce primary immune responses.

25 Eosinophils were not required for primary immune responses.

26 and plays a critical role in the outcome of primary immune responses.

27 regulation, tumour surveillance and specific primary immune responses.

28 bility to stimulate resting naive T cells in primary immune responses.

29 city to stimulate naive T cells and initiate primary immune responses.

30 g cells that play a major role in initiating primary immune responses.

31 f 4-1BB costimulation for the development of primary immune responses, 4-1BBL-deficient (4-1BBL-/-) m

32 Following a primary immune response, a portion of effector T cells g

33 ow that CD86 is very effective in inducing a primary immune response against Line 1.

34 rom skin to regional lymph nodes to initiate primary immune responses against Ag encountered in skin.

35 lls, are thought to be crucial in triggering primary immune responses against both the graft and the

36 hat IFN-gamma plays an important role during primary immune responses against Friend virus but is dis

37 T cells into the memory compartment during a primary immune response also drive a rapid differentiati

38 emulsion alone, accelerated induction of the primary immune response and broadened its durability aga

39 germinal centre (GC) kinetics of the primed primary immune response and on affinity maturation obser

40 Ag was the superior means of both inducing a primary immune response and priming the mice to respond

41 olving HIV-1-suppressive activity during the primary immune response and that this activity is compri

42 naive CD4+ T cell exposure to antigen in the primary immune response and the quality of the memory ce

43 ry T cells represent a small fraction of the primary immune response and, at early time points, their

44 ) T cells showed signs of aging during their primary immune responses and differentiated into tissue-

45 Studies showed that AM14 RF B cells can make primary immune responses and do not downregulate sIgM, i

46 G-protein-coupled receptors is necessary for primary immune responses and for homing of leukocytes to

47 tery tertiary lymphoid organs participate in primary immune responses and organize T- and B-cell auto

48 Nonetheless, primary immune responses and the GC reaction in these mi

49 t with IL-12, allowed to progress beyond the primary immune response, and challenged by i.p. injectio

50 hils contribute to larval killing during the primary immune response, and neutrophils are effector ce

51 function as natural adjuvants to stimulate a primary immune response, and they may represent the natu

52 sm that may operate during the initiation of primary immune responses, and may prove useful as a stra

53 The primary immune response appears first and is inhibited b

54 ntrast, the presence of CD4 cells during the primary immune response appears to play a significant ro

55 clones that have expanded massively during a primary immune response are more prone to die as a resul

56 -specific T and B cells participating in the primary immune response are rapidly eliminated, but some

57 Primary immune responses are thought to be induced by de

58 hat diverse effector cell types arise in the primary immune response as a result of heterogeneity in

59 does not control CD4+ T-cell entry into the primary immune response, as a diverse range in affinity

60 lec1b(fl/fl)PF4-Cre mice are able to sustain primary immune responses but show a defect in immune cel

61 resenting cells are unable to sensitize in a primary immune response, but actively induce antigenic t

62 d that IL-2 sometimes contributes to optimal primary immune responses, but it is not mandatory.

63 ot only exhibit the unique capacity to evoke primary immune responses, but may also acquire TLR-trigg

64 s are not only critical for the induction of primary immune responses, but may also be important for

65 s of inflammation to lymph nodes to initiate primary immune responses, but the molecular mechanisms b

66 Isolation was achieved during the primary immune response by surface staining and flow cyt

67 responses by an adoptive transfer assay and primary immune responses by in vivo treatment of influen

68 We examined the induction of primary immune responses by insoluble GLU polypeptide de

69 These studies suggest that induction of primary immune responses by rAd5 gut immunization and su

70 Secondary lymphoid organs (SLOs) promote primary immune responses by recruiting naive lymphocytes

71 During a primary immune response CD8(+) T cells experience divers

72 Despite their critical function as APCs for primary immune responses, dendritic cells (DC) and Lange

73 Due to their capacity to induce primary immune responses, dendritic cells (DC) are attra

74 a potential deleterious role for Axl during primary immune responses directed against A. fumigatus a

75 a potential deleterious role for CCR7 during primary immune responses directed against A. fumigatus.

76 These experiments show that primary immune responses disappear in the absence of a t

77 sory molecules in cytokine production during primary immune responses, Drosophila cell lines expressi

78 ucleatum and human antimicrobial peptides in primary immune responses elicited by oral epithelium.

79 These findings suggest that there may be a primary immune response generated within the allograft a

80 racellular kinase cascades rapidly activates primary immune response genes.

81 A robust primary immune response has been correlated with the pre

82 ae through an MBP-dependent mechanism in the primary immune response if other effector cells are abse

83 V transformation is associated with a marked primary immune response in cord blood samples predominat

84 nsion are already present at the peak of the primary immune response in mice.

85 erred 0 to 24 h postvaccination stimulated a primary immune response in naive recipients.

86 Lack of primary immune response in severe combined immunodeficie

87 ion of an anti-Gag and -Gag peptide cellular primary immune response in vitro.

88 ions are required for many Th2-cell mediated primary immune responses including the response that fol

89 that have an unequaled capacity to initiate primary immune responses, including tolerogenic response

90 fed transgenic HBsAg potato tubers showed a primary immune response (increases in HBsAg-specific ser

91 e observed during the expansion phase of the primary immune response, indicating early defects in Th

92 Immunoglobulin A (IgA) is the primary immune response induced in the intestine by rota

93 The primary immune response is referred to as PAMP-triggered

94 profoundly reduced naive B cell numbers and primary immune responses, it had a markedly smaller effe

95 results in a functional reprogramming of the primary immune response, marked by altered T cell homing

96 immunity in mice and that the quality of the primary immune response may be playing a hitherto unreco

97 nT) in T cells, and demonstrated that T cell primary immune responses mediated through interaction be

98 es of Ag-specific cells (5-12.5%) similar to primary immune responses observed in vivo in murine mode

99 CXCR4 and CCR5 isolates of HIV-1 during the primary immune response of human CD4+ T cells.

100 that a population of B cells that dominates primary immune responses of BALB/c mice to influenza vir

101 In blood donors, primary immune responses of low and/or high avidity were

102 econdary lymphoid tissue either as a site of primary immune response or as a cache for excess T cell

103 elopment, the impact of low-dose Rapa on the primary immune response, particularly as it relates to f

104 y T cells maintain their predominance as the primary immune response progresses, with no enhancement

105 play an important role in the development of primary immune responses protective against HSV-2.

106 f HIV-specific T cell clones involved in the primary immune response rapidly disappeared.

107 expression inhibits, but does not eliminate, primary immune responses, reducing survival and increasi

108 However, the role of IPCs/PDCs in initiating primary immune responses remains elusive.

109 surface signals directly into T cells during primary immune responses, resulting in intrinsic T cell

110 ted at LBD fragments several weeks after the primary immune response suggests intramolecular epitope

111 After a primary immune response, T cell memory occurs when a sub

112 During the primary immune response, the expansion and contraction o

113 During the primary immune response, the magnitude of the CD4 and CD

114 ses not only avoid elimination by the host's primary immune response, they also remain with the host

115 ntigen-specific T helper (TH) cells during a primary immune response to a protein antigen.

116 ic to unrelated viruses may alter the host's primary immune response to a second virus.

117 ion of alpha146-162 peptide in IFA after the primary immune response to AChR also significantly suppr

118 likelihood for a role of MCs in influencing primary immune response to allergens has grown.

119 al expansion of PS-specific B cells during a primary immune response to an intact bacterium, as well

120 inally, treatment with Chi220 suppressed the primary immune response to cytomegalovirus, resulting in

121 The primary immune response to Gag elicited by rVSV peaked 7

122 Qualitative differences in the primary immune response to HIV (i.e. mobilization of a r

123 nstrated that qualitative differences in the primary immune response to HIV, but not quantitative dif

124 Mice deficient in C3 or Cr2 had an impaired primary immune response to III-PS.

125 duced lower levels of CD8(+) CTLp during the primary immune response to LCMV than did wild-type contr

126 (NK) cells are an important component of the primary immune response to most virus infections.

127 unodominant epitopes are known to suppress a primary immune response to other antigenic determinants

128 Inasmuch as T15-Id+ Abs dominate the primary immune response to PC in normal mice, it was sur

129 quired for the adjuvant effect of C3d on the primary immune response to PPS14 but were necessary for

130 ormalities have no detectable effects on the primary immune response to protein antigens.

131 on immune effector cell function during the primary immune response to several acute infections.

132 In the first week of the primary immune response to the (4-hydroxy-3-nitrophenyl)

133 ulation of these cytokines suggests that the primary immune response to the live infective stage of t

134 r (GC) B cells and plasma cells (PCs) during primary immune responses to a T cell-dependent hapten-pr

135 Primary immune responses to adenoviral vectors and the a

136 ortant in the early cellular response during primary immune responses to allergens.

137 lergic inflammation correlated with enhanced primary immune responses to allergic sensitization and e

138 recent evidence for a MC role in modulating primary immune responses to pathogens, the likelihood fo

139 ion determined by histology, indicating that primary immune responses to VSA(CSA) may not be sufficie

140 The maximum primary immune response was elicited with <0.1 microg of

141 During the primary immune response, we show generation of CD8+ memo

142 T cell-dendritic cell (DC) encounters during primary immune responses, we found that CCL21 addition t

143 All primary immune responses were confirmed by immunoblottin

144 tity, even at relatively early stages of the primary immune response when somatic mutation and clonal

145 pups were not infected and generated normal primary immune responses when challenged as adults.

146 ctive vaccine adjuvants for eliciting strong primary immune responses with a viral protein in vivo, p

147 as concluded that there is redundancy in the primary immune response, with eosinophils killing the la

148 rtial activation of B lymphocytes during the primary immune response, with generation of splenic germ