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1 to stronger opioids when pain control is the primary objective.
2 in autism spectrum disorders (ASDs) with two primary objectives.
3 A-IIIC) met the eligibility criteria for the primary objective analysis, with an additional 22 patien
4 ate the effect of atorvastatin on HIV-1 RNA (primary objective) and cellular markers of immune activa
5 primary endpoint was broken up into three co-primary objectives: disease-free survival in the overall
6                            The study met the primary objective efficacy ICSS end point in demonstrati
7                                          The primary objective efficacy measure (sign) was mean chang
8                                 This study's primary objective examined the relationship between GSK2
9 for marginal association, which is often the primary objective in inference, rather than the main eff
10                                          Our primary objective in this exploratory study was to ident
11 control over crystal structure is one of the primary objectives in crystal growth, the present lack o
12                                          The primary objective included analysis of geometric mean ti
13                   In the setting of PCR, the primary objective is the safe and thorough evacuation of
14                           In this study, our primary objective is to develop a Bayesian hierarchical
15                                          The primary objective is to evaluate histologically and hist
16                                          The primary objective is to evaluate superiority of the prop
17                                          The primary objective is to investigate the safety and toler
18 noted with eltrombopag and the trial met the primary objective of a reduction in CRTEs; eltrombopag m
19                                          The primary objective of acoustic metamaterial research is t
20   Although the presumption is often that the primary objective of asking for family consent is to sec
21 ntaining optimal symptom control remains the primary objective of asthma treatment.
22                                          The primary objective of Children's Oncology Group study P96
23 progression, both in routine care and as the primary objective of clinical trials.
24 particles, understanding that structure is a primary objective of condensed matter research.
25                   The study did not meet its primary objective of demonstrating that fludrocortisone
26      Here, we compare arms A and C, with the primary objective of establishing whether overall surviv
27 nce, the targeted chemical production is the primary objective of MOMAKnock while the MOMA assumption
28 ntrolling nutrient levels in watersheds is a primary objective of most environmental policy.
29                                          The primary objective of noninferiority of the humoral immun
30                                          The primary objective of noninferiority was met: 7 patients
31                                          The primary objective of our study was to determine whether
32                               Therefore, the primary objective of our study was to screen for differe
33                            The study met its primary objective of PFS prolongation with vandetanib ve
34                                 Although the primary objective of reducing the proportion of subjects
35 ERPRETATION: The GOLD study did not meet its primary objective of showing a significant improvement i
36         Designing tight-binding ligands is a primary objective of small-molecule drug discovery.
37                   The study did not meet the primary objective of statistically significant improveme
38                                          The primary objective of such a device is to see if addition
39 3%, 95% confidence interval 76%-91%) met the primary objective of superiority versus the historical c
40                                          The primary objective of the AA5208/OCTANE trial was to comp
41                                          The primary objective of the appropriate use criteria is to
42                                          The primary objective of the AUC is to provide a framework f
43                                          The primary objective of the decision process is to identify
44                                          The primary objective of the INFORM trial was to assess all-
45                                          The primary objective of the KEYNOTE-001 trial was to assess
46                                          The primary objective of the Lessons From Antagonizing the C
47                                          The primary objective of the phase III part of this study wa
48                                    Thus, the primary objective of the present study was to determine
49                                          The primary objective of the research was to determine wheth
50                                          The primary objective of the study was to assess the safety
51                                          The primary objective of the study was to calculate prevalen
52                                          The primary objective of the study was to compare the effect
53                                          The primary objective of the study was to determine whether
54                                          The primary objective of the study was to evaluate the overa
55 sound for dengue fever screening; hence, the primary objective of the study was to evaluate the utili
56 trial), but only the AZA group fulfilled the primary objective of the study.
57                                          The primary objective of the TAVR-LM registry is to evaluate
58                                          The primary objective of the trial was defined as evaluation
59 ons to this nested cohort study are that the primary objective of the trial was designed to measure e
60                                          The primary objective of the trial was event-free survival (
61                                          The primary objective of these two trials was to determine t
62                                            A primary objective of this article was to provide a gener
63                                 An important primary objective of this council is to define the essen
64                                          The primary objective of this international, multicenter, mu
65                                          The primary objective of this international, pivotal, single
66                                          The primary objective of this mechanistic open-label, strati
67                                          The primary objective of this multicenter registry was to st
68                                          The primary objective of this paper was to identify how fore
69                                          The primary objective of this project was to decrease comput
70                                          The primary objective of this project was to determine the a
71                                          The primary objective of this prospective, randomized, doubl
72                                          The primary objective of this randomized trial was to compar
73                                          The primary objective of this retrospective analysis was to
74                                          The primary objective of this study is to compare the preval
75                                          The primary objective of this study is to determine at what
76                                          The primary objective of this study is to dimensionally and
77                                          The primary objective of this study is to histologically eva
78                                          The primary objective of this study is to histologically eva
79                                          The primary objective of this study is to investigate microb
80                                          The primary objective of this study is to investigate the ex
81                                          The primary objective of this study is to use histomorphomet
82                                              Primary objective of this study was the comparison of so
83                                          The primary objective of this study was to assess the change
84                                          The primary objective of this study was to assess the effect
85                                          The primary objective of this study was to assess the status
86                                          The primary objective of this study was to compare antibody
87                                          The primary objective of this study was to compare the biodi
88                                          The primary objective of this study was to compare the survi
89                                          The primary objective of this study was to describe and asse
90                                          The primary objective of this study was to determine if thes
91                                          The primary objective of this study was to determine outcome
92                                          The primary objective of this study was to determine whether
93                                          The primary objective of this study was to determine whether
94                                              Primary objective of this study was to determine whether
95                                          The primary objective of this study was to develop an image-
96                                          The primary objective of this study was to elucidate mechani
97                                          The primary objective of this study was to establish endotyp
98                                          The primary objective of this study was to evaluate a range
99                                          The primary objective of this study was to evaluate the asso
100                                          The primary objective of this study was to evaluate the asso
101                                          The primary objective of this study was to evaluate the caus
102                                          The primary objective of this study was to evaluate the low-
103                                          The primary objective of this study was to evaluate the phys
104                                          The primary objective of this study was to evaluate the repr
105                                          The primary objective of this study was to evaluate the resp
106                                          The primary objective of this study was to evaluate the safe
107                                          The primary objective of this study was to evaluate the safe
108                                          The primary objective of this study was to examine the nutri
109                                          The primary objective of this study was to find a mechanisti
110                                          The primary objective of this study was to identify factors
111                                          The primary objective of this study was to identify which pa
112                                          The primary objective of this study was to investigate five
113                                          The primary objective of this study was to obtain insights i
114                                          The primary objective of this study was to test whether para
115                                          The primary objective of this study was to use propensity sc
116                                          The primary objective of this study was to utilize MR molecu
117                                 This was the primary objective of this study, attained through two sp
118 for a correction of overlapping peaks is the primary objective of this study.
119                                          The primary objective of this systematic review and meta-ana
120                                          The primary objective of this trial was to evaluate safety o
121 ta for the phase 1 portion of the study, the primary objective of which was to establish the recommen
122 ociated independent monitoring strategy, the primary objective of which was verification that tOPV wa
123                                   One of the primary objectives of early visual processing is the det
124  relative protein quantification, one of the primary objectives of mass spectrometry based proteomics
125                                   One of the primary objectives of the intensive campaign was to inve
126                                          The primary objectives of the study were to assess safety an
127                           Therefore, the two primary objectives of this investigation were to charact
128                                          The primary objectives of this study were to describe the fr
129                                          The primary objectives of this systematic review on oncoplas
130                                          The primary objectives of this trial were to determine safet
131 eport the prespecified final analysis of the primary objectives, OS and adverse events.
132 but if particulate matter reductions are the primary objective, other approaches to time-differentiat
133           The model's discrimination for the primary objective performed better than the European Gro
134                  End points included safety (primary), objective response rate, and overall survival
135 -forming units) were required to achieve the primary objective, resulting in attack rates of 55% (11/
136                               Safety was the primary objective; secondary objectives included standar
137 tional longitudinal studies, having as their primary objective the creation of postnatal growth chart
138                                      For the primary objective, the gingival thickness that best corr
139                            The study met its primary objective to demonstrate the superiority of CE o
140  Bangladesh, were enrolled in a study with a primary objective to establish noninferiority of concomi
141 0 is a prospective, multicenter study with a primary objective to evaluate the diagnostic accuracy of
142                                          The primary objective (to determine the maximum tolerated do
143                                          The primary objective was 1-year event-free survival (EFS) a
144                                          Our primary objective was a comprehensive re-estimation of d
145                                   The part 2 primary objective was assessed by a composite primary en
146                                          The primary objective was assessment of antitumor activity u
147                                              Primary objective was assessment of patient discomfort i
148                                          The primary objective was assessment of safety; secondary en
149                                          The primary objective was comparison of PFS between the two
150                                          The primary objective was comparison of the proportion of pa
151                                          The primary objective was complete response (CR).
152                                          The primary objective was DFS in patients with ER-positive B
153                                          The primary objective was feasibility, defined as the propor
154                                          The primary objective was identifying the number of patients
155                                          The primary objective was met in both treatment arms.
156                                          The primary objective was mortality after subarachnoid hemor
157                                 Although the primary objective was not met, subgroup analyses showed
158                                          The primary objective was overall and complete response rate
159                                          The primary objective was prediction of overall mortality (O
160                                          The primary objective was product-related AEs.
161                                          The primary objective was progression-free survival in the i
162                                          The primary objective was recurrence-free survival (RFS), an
163                                          The primary objective was response rate in patients with thy
164                                          The primary objective was safety (incidence of adverse event
165                                          The primary objective was safety and immunogenicity of the Z
166                                          The primary objective was safety and tolerability 28 days po
167                                          The primary objective was safety and tolerability of RG-101.
168                                          The primary objective was safety and tolerability of the com
169                                          The primary objective was safety and tolerability, with seve
170                                          The primary objective was safety evaluation.
171                                          The primary objective was safety, including antibody testing
172                                          The primary objective was the cumulative incidence of death,
173                                          The primary objective was the healing of rickets, as assesse
174                                          The primary objective was the major molecular response (MMol
175                                          The primary objective was the rate of hematologic normalizat
176                                          The primary objective was the vaccine effectiveness of at le
177                                          Our primary objective was to assess feasibility and safety;
178 in insulin-resistant muscle are unknown, our primary objective was to assess insulin-stimulated GU, p
179                                          Our primary objective was to assess protective efficacy agai
180                                          The primary objective was to assess safety and tolerability
181                                          The primary objective was to assess safety and tolerability
182                                          The primary objective was to assess safety and tolerability.
183                                          The primary objective was to assess safety and tolerability.
184                                          The primary objective was to assess safety at 12 weeks after
185                                          The primary objective was to assess safety, tolerability, an
186                                          The primary objective was to assess safety; secondary object
187                                          The primary objective was to assess the clinical efficacy of
188                                          The primary objective was to assess the effect of telaprevir
189                                          The primary objective was to assess the effectiveness of TDF
190                                          The primary objective was to assess the efficacy of the vacc
191                                          Our primary objective was to assess the impact of mineraloco
192                                          The primary objective was to assess the long-term safety pro
193                                          The primary objective was to assess the safety and tolerabil
194                                          Our primary objective was to assess the safety and tolerabil
195                                          The primary objective was to assess the safety of self-admin
196                                          The primary objective was to assess the superiority of bOPV-
197                                          Our primary objective was to characterise product safety, an
198                                      TENOR's primary objective was to characterize the natural histor
199                                          The primary objective was to compare antirotavirus immunoglo
200                                          The primary objective was to compare disease-free survival b
201                                          The primary objective was to compare major adverse cardiovas
202                                          The primary objective was to compare overall survival (OS) i
203                                          The primary objective was to compare progression-free surviv
204                                          The primary objective was to compare progression-free surviv
205                                          The primary objective was to compare targeted and standard b
206                                          The primary objective was to compare the number of patients
207                                          The primary objective was to compare the tracheal sealing pe
208                                          Our primary objective was to define the incidence of at leas
209                                          The primary objective was to demonstrate improvement in prog
210                                          The primary objective was to demonstrate noninferiority (10%
211                                              Primary objective was to demonstrate noninferiority of d
212                                          The primary objective was to demonstrate noninferiority of t
213                                          The primary objective was to demonstrate the clinical applic
214                                          The primary objective was to demonstrate the superiority of
215                                          Our primary objective was to design and test the efficacy ov
216                                          The primary objective was to determine a recommended phase 2
217                                          The primary objective was to determine fatty acid compositio
218                                          The primary objective was to determine GED-0301's effect on
219                                          The primary objective was to determine if ALC prevents CIPN
220                                          The primary objective was to determine if colistin dose (mg
221                                          The primary objective was to determine if wireless remote mo
222                                              Primary objective was to determine pharmacokinetics, saf
223                                          The primary objective was to determine safety, toxicity, and
224                                          The primary objective was to determine the difference in NK
225                                          Our primary objective was to determine the dose-response rel
226                                              Primary objective was to determine the effect of AR per
227                           In this study, our primary objective was to determine the effect of timing
228                                          Our primary objective was to determine the effect on risk of
229                                          The primary objective was to determine the maximum tolerated
230 tients received 28-day treatment cycles; the primary objective was to determine the maximum tolerated
231                                          The primary objective was to determine the maximum tolerated
232                                          The primary objective was to determine the overall response
233                                          The primary objective was to determine the safety of the vac
234                                          The primary objective was to determine the vascular effects
235                                          Our primary objective was to determine whether adding GO to
236                                          Our primary objective was to determine whether interleukin-1
237                                          Our primary objective was to determine whether peanut OIT ca
238                                          Our primary objective was to determine whether previous radi
239                                          The primary objective was to determine whether programmed hi
240                                          The primary objective was to determine whether spironolacton
241                                          The primary objective was to determine whether vandetanib 10
242                                          The primary objective was to develop a coupled exposure-dose
243                                 This study's primary objective was to develop a procedure to measure
244                                          The primary objective was to establish noninferiority of lap
245                                          The primary objective was to establish the maximum tolerated
246                                          The primary objective was to establish the safety and tolera
247                                          Our primary objective was to estimate the proportion of all
248                                          The primary objective was to estimate the toxicity contour o
249 st severe form of systemic inflammation, the primary objective was to evaluate chronic pain states an
250                                          The primary objective was to evaluate HPV-16/18 antibody res
251                                          The primary objective was to evaluate overall survival at 1
252                                          The primary objective was to evaluate the dose-response rela
253                                          The primary objective was to evaluate the efficacy of citalo
254                                          The primary objective was to evaluate the efficacy of omaliz
255                                          The primary objective was to evaluate the feasibility of sur
256                                          Our primary objective was to evaluate the outcomes of minima
257                  In the phase 2 portion, the primary objective was to evaluate the overall response r
258                                          The primary objective was to evaluate the safety and determi
259                                          The primary objective was to evaluate the safety and tolerab
260                                          Our primary objective was to examine whether the interventio
261                                          The primary objective was to explore the association between
262                                              Primary objective was to identify factors associated wit
263                                              Primary objective was to identify leukocyte subsets that
264                                          The primary objective was to identify the maximum tolerated
265                                          The primary objective was to identify the safety and tolerab
266                                          Our primary objective was to investigate a biomarker driven
267                                          The primary objective was to investigate the effect of the S
268                                          The primary objective was to measure, for the first time, th
269                  MAIN OUTCOMES MEASURES: The primary objective was to show noninferiority of ranibizu
270                                          The primary objective was to show superiority in progression
271                                          The primary objective was to show superiority of QVA149 vers
272                                          The primary objective was to test for an improvement in even
273                                          Our primary objective was to test for associations of the us
274                                          The primary objective was to test the ability of a laparosco
275                                          The primary objective was to test the hypothesis that the me
276                                          The primary objective was to test the hypothesis that the tr
277 ffectiveness of the HRV vaccination program (primary objective) was measured by comparing the inciden
278                                      The two primary objectives were investigator-assessed progressio
279                                          The primary objectives were MTD evaluation and response to R
280                                          The primary objectives were overall response rate (ORR) by i
281                                          The primary objectives were safety and tolerability.
282                                              Primary objectives were safety and tolerability.
283                                          The primary objectives were safety in patients who received
284                                          The primary objectives were safety, tolerability, characteri
285                                          The primary objectives were the HZ/su vaccine response rate
286                                          The primary objectives were to assess feasibility and safety
287                                          The primary objectives were to assess the diversity, distrib
288                                              Primary objectives were to assess the safety and the max
289                                              Primary objectives were to assess the safety of rovalpit
290                                          Our primary objectives were to assess the safety profile and
291                                  Methods The primary objectives were to assess tolerability, pharmaco
292                                              Primary objectives were to assess whether low sFlt-1:PlG
293                           In this study, our primary objectives were to clone the fathead minnow (FHM
294  In the phase 1 dose-escalation portion, the primary objectives were to determine the incidence of do
295                                              Primary objectives were to determine the maximum tolerat
296                                          The primary objectives were to establish individual readers'
297                                          The primary objectives were to establish the maximum tolerat
298                                          The primary objectives were to estimate and compare the sens
299                                          The primary objectives were to evaluate the safety of MVA an
300                                              Primary objectives were: confirmed prostate-specific ant

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