ライフサイエンスコーパス: primary open-angle glaucoma

1 th juvenile glaucoma and some cases of adult primary open angle glaucoma.

2 (s) of TIGR/MYOC in both steroid-induced and primary open angle glaucoma.

3 ssociated with both juvenile-and adult-onset primary open angle glaucoma.

4 rove early diagnosis of visual field loss in primary open angle glaucoma.

5 oss is measurable by conventional methods in primary open angle glaucoma.

6 has been associated with the development of primary open angle glaucoma.

7 nce for genetic heterogeneity of adult-onset primary open angle glaucoma.

8 e damage, is involved in the pathogenesis of primary open angle glaucoma.

9 ous ocular diseases, such as keratoconus and primary open angle glaucoma.

10 ed 50 mmHg and he was found to have advanced primary open angle glaucoma.

11 es in a transgenic mouse model of hereditary primary open-angle glaucoma.

12 similar at baseline; 68% were diagnosed with primary open-angle glaucoma.

13 F-beta2 because TGF-beta2 is associated with primary open-angle glaucoma.

14 are associated with juvenile and adult-onset primary open-angle glaucoma.

15 N gene may lead to juvenile- and adult-onset primary open-angle glaucoma.

16 ween antioxidant consumption and the risk of primary open-angle glaucoma.

17 s in the initial management of patients with primary open-angle glaucoma.

18 documented to occur in eyes of patients with primary open-angle glaucoma.

19 surgical therapy are similar to treatment of primary open-angle glaucoma.

20 eature of the outflow system in aging and in primary open-angle glaucoma.

21 hwork and possibly some of the extra loss in primary open-angle glaucoma.

22 rat model appears to mimic some features of primary open-angle glaucoma.

23 also may be involved in the pathogenesis of primary open-angle glaucoma.

24 from juvenile glaucoma to typical late-onset primary open-angle glaucoma.

25 may contribute to changes seen with age and primary open-angle glaucoma.

26 male), 16 had ocular hypertension and 14 had primary open-angle glaucoma.

27 risk and be a new risk factor to consider in primary open-angle glaucoma.

28 ffective in lowering intraocular pressure in primary open-angle glaucoma.

29 gene are the most common genetic factors of primary open-angle glaucoma.

30 g the onset of the prevalent ocular disorder primary open-angle glaucoma.

31 ) which have previously been associated with primary open-angle glaucoma.

32 ing diabetic retinopathy, uveoretinitis, and primary open-angle glaucoma.

33 related to mutations in the MYOCILIN gene is primary open-angle glaucoma.

34 forms of myocilin, a protein associated with primary open-angle glaucoma.

35 N gene may lead to juvenile- and adult-onset primary open-angle glaucoma.

36 ay be on a multiple topical drug regimen for primary open-angle glaucoma.

37 spective study included 122 eyes treated for primary open angle glaucoma, 50 eyes (study group) in wh

38 identified 354 eyes in 180 subjects (97 with primary open-angle glaucoma, 83 with glaucoma suspicion)

39 he potential role of superoxide dismutase in primary open angle glaucoma, a disorder of the aging tra

40 The etiology of primary open angle glaucoma, a leading cause of age-rela

41 laucoma have identified novel loci for POAG (primary-open-angle glaucoma) (ABCA1, AFAP1, GMDS, PMM2,

42 educed cell survival is also associated with primary open angle glaucoma, ageing, cellular senescence

43 aucoma, one locus (GLC1A) for juvenile-onset primary open angle glaucoma and a further two loci (GLC1

44 essure is a highly heritable risk factor for primary open angle glaucoma and currently the only targe

45 mans with Weill-Marchesani-like syndrome and primary open angle glaucoma and ectopia lentis in dogs.

46 ng female patient with choroidal infarction, primary open angle glaucoma and Flammer syndrome.

47 Twenty-one patients with newly diagnosed primary open-angle glaucoma and 34 age- and gender-match

48 We screened 716 patients with primary open-angle glaucoma and 596 control subjects for

49 amples were collected from 111 patients with primary open-angle glaucoma and an age-matched control g

50 A total of 609 patients (609 eyes) with primary open-angle glaucoma and cataract were included.

51 of dementia, including Alzheimer's disease, primary open-angle glaucoma and Helicobacter pylori (H.p

52 in which CCT has been implicated, including primary open-angle glaucoma and keratoconus.

53 ts with NTG when compared with patients with primary open-angle glaucoma and nonglaucomatous control

54 traocular lens implantation in patients with primary open-angle glaucoma and ocular hypertension.

55 The two most common types of glaucoma--primary open-angle glaucoma and primary angle-closure gl

56 ntly identified as causative for adult-onset primary open-angle glaucoma and provides additional evid

57 One eye per patient with primary open-angle glaucoma and stable intraocular press

58 d from patients undergoing trabeculotomy for primary open-angle glaucoma and the normal aqueous from

59 asured by 24-2 and 10-2 VFs in patients with primary open-angle glaucoma and to test the hypothesis t

60 A total of 234 patients (104 with primary open angle glaucoma, and 130 control subjects wi

61 wed up until death; 203 patients (65.7%) had primary open-angle glaucoma, and 106 patients (34.2%) ha

62 n "high-pressure" forms of glaucoma, such as primary open-angle glaucoma, and in cases in which the i

63 tis pigmentosa, while Bardet-Biedl syndrome, primary open-angle glaucoma, and tumor cell invasiveness

64 these mice may be useful as a mouse model of primary open angle glaucoma as well as for assessing the

65 t quintile have a 2.5-fold increased risk of primary open-angle glaucoma as compared with those in th

66 To determine the stage of primary open angle glaucoma at presentation at a tertiar

67 utoimmune uveitis, diabetic retinopathy, and primary open angle glaucoma, but its role in normal visi

68 autosomal dominant juvenile- and adult-onset primary open angle glaucoma, but the mechanism by which

69 ive oxygen species play a pathogenic role in primary open angle glaucoma by fostering changes that re

70 the gene have been found in 2-4% of sporadic primary open angle glaucoma cases.

71 ed, and they lead to approximately 5% of all primary open-angle glaucoma cases.

72 of the posterior sclera in a canine model of primary open-angle glaucoma caused by the G661R missense

73 -85 years with a minimum 2-year diagnosis of primary open-angle glaucoma, chronic primary angle-closu

74 The pooled multivariate rate ratios for primary open-angle glaucoma comparing the highest versus

75 s elevated in aqueous humor of patients with primary open-angle glaucoma, contributes to the increase

76 rmal eyes and of the increased resistance in primary open-angle glaucoma eyes (POAG).

77 Primary open angle glaucoma (GLC1) is a common ocular di

78 e of progression from ocular hypertension to primary open-angle glaucoma has been established in the

79 sty reduces elevated intraocular pressure in primary open-angle glaucoma has been established.

80 the progression from ocular hypertension to primary open-angle glaucoma has been the subject of two

81 he authors investigated the genetic cause of primary open angle glaucoma in a large four-generation f

82 ld female was being followed and treated for primary open angle glaucoma in our tertiary referral cen

83 lance of benefits and harms of screening for primary open-angle glaucoma in adults.

84 variants of LOXL1 play a significant role in primary open-angle glaucoma in the Caucasian, African-Am

85 nces may contribute to the predisposition of primary open-angle glaucoma in various high-risk populat

86 o cause the most common form of the disease, primary open angle glaucoma, in selected families.

87 It may also be important in primary open angle glaucoma influencing aqueous outflow.

88 Adult onset primary open angle glaucoma is a leading cause of blindn

89 associated with progression of patients with primary open angle glaucoma is essential to our clinical

90 CACNA2D1 single-nucleotide polymorphism and primary open angle glaucoma is found.

91 Primary open angle glaucoma is the most prevalent type o

92 Primary open-angle glaucoma is a progressive optic neuro

93 Primary open-angle glaucoma is characterized by increase

94 number of persons in the United States with primary open-angle glaucoma is estimated to be 2.47 mill

95 The common form of adult-onset primary open-angle glaucoma is inherited as a complex tr

96 Primary open-angle glaucoma is the second leading cause

97 s not contain any of the previously reported primary open angle glaucoma loci.

98 This study identifies a new primary open angle glaucoma locus, GLC1Q, in a region on

99 size (P < 0.001) in both eyes with incident primary open-angle glaucoma (mean, 10.6%; standard devia

100 yndrome (MetS) with intraocular pressure and primary open angle glaucoma (OAG) have been reported.

101 Primary open-angle glaucoma (OAG) was diagnosed in 3.1%

102 ce or ocular hypertension, and patients with primary open angle glaucoma or primary angle closure gla

103 A total of 560 patients with primary open-angle glaucoma or ocular hypertension who h

104 ation of 0.005% (50 mug/mL) in patients with primary open-angle glaucoma or ocular hypertension.

105 ) and dorz/brim/tim in Mexican patients with primary open-angle glaucoma or ocular hypertension.

106 5; 95% CI, 1.31-10.13; P = .01), presence of primary open-angle glaucoma (OR, 3.82; 95% CI, 1.60-9.14

107 e of trabeculectomy surgery in patients with primary open angle glaucoma over a 3-year period of foll

108 ely 1.8 fold; n=20) in AH derived from human primary open angle glaucoma patients as compared to AH d

109 tly was shown to harbor mutations in 2-4% of primary open angle glaucoma patients.

110 el), volume (ONVol), and flow (ONFlow) in 19 primary open-angle glaucoma patients and 15 age-matched

111 ce glaucoma and that disease pathogenesis in primary open-angle glaucoma patients is dependent upon t

112 th early paracentral visual field defects in primary open-angle glaucoma patients.

113 us level of TGF-beta2 has been found in many primary open-angle glaucoma patients.

114 The study included patients with primary open angle glaucoma (POAG group, n = 30) and con

115 12 normal controls, 7 patients with primary open angle glaucoma (POAG) and 9 patients with n

116 neurin (OPTN) are linked to the pathology of primary open angle glaucoma (POAG) and amyotrophic later

117 and alleles frequencies in primary glaucoma [primary open angle glaucoma (POAG) and primary angle clo

118 tly has testing for a disease risk factor in primary open angle glaucoma (POAG) become available.

119 nctional changes of optic nerve in eyes with primary open angle glaucoma (POAG) by the joint use of o

120 re recently associated with 6.0% of cases of primary open angle glaucoma (POAG) in patients from Oreg

121 ltiple loci have been associated with either primary open angle glaucoma (POAG) or heritable ocular q

122 e sought between groups of eyes differing in primary open angle glaucoma (POAG) outcome, how POAG was

123 optosis (codon 72 Pro/Arg) and the subset of primary open angle glaucoma (POAG) patients with early l

124 Control TM and most primary open angle glaucoma (POAG) TM were collected fro

125 s in the beagle model of autosomal recessive primary open angle glaucoma (POAG) to a 4-Mb interval on

126 mutations in the myocilin (MYOC) gene cause primary open angle glaucoma (POAG) with varying age-of-o

127 ollow-up of 30.8 months, including 28 (4.4%) primary open angle glaucoma (POAG), 27 (4.2%) primary an

128 five subjects were glaucomatous: (67 PXG, 42 Primary Open Angle Glaucoma (POAG), 28 PACG, 14 Normal T

129 Primary open angle glaucoma (POAG), a major cause of bli

130 (MYOC) are the most common genetic cause of primary open angle glaucoma (POAG), but the mechanisms u

131 omplex 1 defects also occur in patients with primary open angle glaucoma (POAG), in which there is sp

132 Genetically complex disorders, such as primary open angle glaucoma (POAG), may include highly h

133 The mean IOP for primary open angle glaucoma (POAG), ocular hypertension

134 ity clinic or glaucoma faculty patients with primary open angle glaucoma (POAG), ocular hypertension

135 (MMP) in the aqueous humor of patients with primary open angle glaucoma (POAG), pseudoexfoliation sy

136 esembles several characteristics observed in primary open angle glaucoma (POAG).

137 very closely mimics the pathologic course of primary open angle glaucoma (POAG).

138 retinogram (ERG) is reduced in patients with primary open angle glaucoma (POAG).

139 identified 61 patients (80 procedures) with primary open angle glaucoma (POAG).

140 IOP is a principal risk factor for primary open-angle glaucoma (POAG) a leading cause of bl

141 Primary open-angle glaucoma (POAG) affects 33 million in

142 nd trabecular meshwork (TM) of patients with primary open-angle glaucoma (POAG) and appears to contri

143 enetic association of known loci for IOP and primary open-angle glaucoma (POAG) and identify four new

144 ed to assess the NOS-2 level in the ONH from primary open-angle glaucoma (POAG) and nonglaucomatous h

145 haracterize the role of osteopontin (OPN) in primary open-angle glaucoma (POAG) and normal eyes.

146 becular meshwork (TM) height differs between primary open-angle glaucoma (POAG) and primary angle-clo

147 ematically examined the global prevalence of primary open-angle glaucoma (POAG) and primary angle-clo

148 atched subjects, one of each pair with early primary open-angle glaucoma (POAG) and the other with no

149 thelin (ET)-1 are increased in patients with primary open-angle glaucoma (POAG) as well as in animal

150 ) has been implicated in the pathogenesis of primary open-angle glaucoma (POAG) based on elevated lev

151 and damage to the optic disc in humans with primary open-angle glaucoma (POAG) can be measured using

152 (40+ days) endophthalmitis and risk of a new primary open-angle glaucoma (POAG) diagnosis within 365

153 proteinases (TIMPs) in the aqueous humour of primary open-angle glaucoma (POAG) eyes have been descri

154 erformed a genome-wide association study for primary open-angle glaucoma (POAG) in 1,007 cases with h

155 er trabeculoplasty (SLT) as sole therapy for primary open-angle glaucoma (POAG) in an Afro-Caribbean

156 enlo Park, CA) for treating mild-to-moderate primary open-angle glaucoma (POAG) in patients undergoin

157 A, and CDKN2B genes has been associated with primary open-angle glaucoma (POAG) in several independen

158 Primary open-angle glaucoma (POAG) is a blinding disease

159 Primary open-angle glaucoma (POAG) is a complex disease

160 Primary open-angle glaucoma (POAG) is a complex disease

161 Primary open-angle glaucoma (POAG) is a complex inherite

162 Primary open-angle glaucoma (POAG) is a genetically comp

163 Primary open-angle glaucoma (POAG) is a genetically comp

164 Primary open-angle glaucoma (POAG) is a highly prevalent

165 Primary open-angle glaucoma (POAG) is a leading cause of

166 Primary open-angle glaucoma (POAG) is a leading cause of

167 Primary open-angle glaucoma (POAG) is a leading cause of

168 Primary open-angle glaucoma (POAG) is a major cause of b

169 Primary open-angle glaucoma (POAG) is a major cause of i

170 sk factor for optic nerve damage in cases of primary open-angle glaucoma (POAG) is an increased intra

171 Primary open-angle glaucoma (POAG) is associated with a

172 The primary causative factor of primary open-angle glaucoma (POAG) is elevated intraocul

173 Adult-onset primary open-angle glaucoma (POAG) is the most common fo

174 Primary open-angle glaucoma (POAG) is the second leading

175 rein, we report mapping of a new adult-onset primary open-angle glaucoma (POAG) locus on 5q22.1 (GLC1

176 retinal venous pressure (RVP) in the eyes of primary open-angle glaucoma (POAG) patients and healthy

177 ess the difference in severity of disease in primary open-angle glaucoma (POAG) patients with a Myoci

178 tus (solitary determination) was examined in primary open-angle glaucoma (POAG) patients with catarac

179 emodeling can cause fibrosis of the TM as in primary open-angle glaucoma (POAG) patients, and is char

180 eyedrops in ocular hypertensive (OH) and in primary open-angle glaucoma (POAG) patients.

181 e to the American Academy of Ophthalmology's Primary Open-angle Glaucoma (POAG) Preferred Practice Pa

182 , was identified by sequencing an EST in the primary open-angle glaucoma (POAG) region on 3q21.

183 rent literature continues to be that NTG and primary open-angle glaucoma (POAG) represent a continuum

184 Analysis of aqueous humor from patients with primary open-angle glaucoma (POAG) revealed marked incre

185 Economic viability of treatments for primary open-angle glaucoma (POAG) should be assessed ob

186 the type and amount of GAGs in normal and in primary open-angle glaucoma (POAG) TM and adjacent anter

187 The beagle model of primary open-angle glaucoma (POAG) was used to correlate

188 prevalence was 1.24% (95% CI, 1.14-1.34) for primary open-angle glaucoma (POAG), 0.39% (95% CI, 0.34-

189 We studied 1 eye of 63 primary open-angle glaucoma (POAG), 30 ocular hypertensi

190 enomic region previously was associated with primary open-angle glaucoma (POAG), although replication

191 ressure in greater than 90% of patients with primary open-angle glaucoma (POAG), compared with 30% to

192 G); 1 of the 4 forms of open-angle glaucoma: primary open-angle glaucoma (POAG), normal-tension glauc

193 Primary open-angle glaucoma (POAG), the most common opti

194 In cadaver eyes with primary open-angle glaucoma (POAG), TSP1 is increased in

195 ) are the most common known genetic cause of primary open-angle glaucoma (POAG).

196 ated disorders of blindness, with a focus on primary open-angle glaucoma (POAG).

197 enes for population-specific genetic risk of primary open-angle glaucoma (POAG).

198 for insights into the molecular pathology of primary open-angle glaucoma (POAG).

199 are involved in the etiology of adult-onset primary open-angle glaucoma (POAG).

200 ylation of aqueous humor sCD44 in normal and primary open-angle glaucoma (POAG).

201 erapies for retinal ganglion cells (RGCs) in primary open-angle glaucoma (POAG).

202 mined dietary fat consumption in relation to primary open-angle glaucoma (POAG).

203 ce of aqueous outflow and the development of primary open-angle glaucoma (POAG).

204 ctroretinogram (PERG) in the early stages of primary open-angle glaucoma (POAG).

205 al dysfunction, which has been implicated in primary open-angle glaucoma (POAG).

206 blood flow autoregulation are implicated in primary open-angle glaucoma (POAG).

207 develop a secondary glaucoma that resembles primary open-angle glaucoma (POAG).

208 sting that PMH use may decrease the risk for primary open-angle glaucoma (POAG).

209 in the TM, similar to those associated with primary open-angle glaucoma (POAG).

210 raocular pressure (IOP) in the evaluation of primary open-angle glaucoma (POAG); and to determine the

211 rrhage (ODH) before and after development of primary open-angle glaucoma (POAG); determine the progno

212 confidence interval, 3.3-5.4), consisting of primary open-angle glaucoma (POAG, 3.2%, including high-

213 85; 1995-2013) to estimate effects of T2D on primary open-angle glaucoma (POAG; 3,554 cases).

214 sera from 65 patients with glaucoma (25 with primary open-angle glaucoma [POAG]; 40 with normal-press

215 PRIMARY OPEN-ANGLE GLAUCOMA PREFERRED PRACTICE PATTERN(R

216 (R) GUIDELINES: Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern(R

217 to identify possible risk factors leading to primary open angle glaucoma progression and blindness.

218 f prostaglandin analog eye drops in treating primary open-angle glaucoma, published between December

219 expressed sequence tag, which maps near the primary open angle glaucoma region on chromosome 3q21, s

220 ation between dietary antioxidant intake and primary open-angle glaucoma risk was examined in partici

221 ons with suspected glaucoma or patients with primary open-angle glaucoma, selected to have clinically

222 Primary open-angle glaucoma, status as a glaucoma suspec

223 PRIMARY OPEN-ANGLE GLAUCOMA SUSPECT PREFERRED PRACTICE P

224 he diagnosis and management of patients with primary open-angle glaucoma suspect with detailed recomm

225 In 57 patients with primary open-angle glaucoma, the IOP decreased by 7.7 mm

226 ry cause of elevated intraocular pressure in primary open-angle glaucoma, the present study was condu

227 Risk factors for primary open-angle glaucoma-the most common form of glau

228 that Cochlin contributes to elevated IOP in primary open angle glaucoma through altered interactions

229 Lucia with medically treated primary open-angle glaucoma underwent a 30-day washout,

230 The prevalence of primary open-angle glaucoma was 6.8% overall, increasing

231 Primary open-angle glaucoma was the underlying diagnosis

232 , 45 clinical questions on the management of primary open-angle glaucoma were derived from practice g

233 -82 years) with ocular hypertension or early primary open-angle glaucoma were enrolled.

234 One of the major causes of blindness is primary open-angle glaucoma, which affects millions of e

235 to January 1, 2013, including patients with primary open-angle glaucoma who had a best-corrected vis

236 A total of 603 patients (603 eyes) with primary open-angle glaucoma who were using up to 3 glauc

237 The analysis included 186 patients with primary open-angle glaucoma with a mean age of 59.1 year

238 enotyping was performed in 117 patients with primary open-angle glaucoma with a minimum treatment dur

239 he diagnosis and management of patients with primary open-angle glaucoma with an algorithm for patien

240 -related quality of life among patients with primary open-angle glaucoma with structural macular reti

241 es confirmed by medical chart review to have primary open-angle glaucoma with visual field loss.