ライフサイエンスコーパス: primary progressive aphasia

1 s within language network in each variant of primary progressive aphasia.

2 temporoparietal regions in logopenic variant primary progressive aphasia.

3 tients represent a fourth variant of 'mixed' primary progressive aphasia.

4 atrophy, making this syndrome distinct from primary progressive aphasia.

5 language tests; hence, none met criteria for primary progressive aphasia.

6 matter changes that occur in the variants of primary progressive aphasia.

7 l in the multimodal diagnostic evaluation of primary progressive aphasia.

8 ed through detailed studies of patients with primary progressive aphasia.

9 tributed atrophy pattern in semantic variant primary progressive aphasia.

10 nges in the non-fluent/agrammatic variant of primary progressive aphasia.

11 ical atrophy and eight for logopenic variant primary progressive aphasia.

12 cits are highly variable in individuals with primary progressive aphasia.

13 seen in most patients with semantic variant primary progressive aphasia.

14 in 43 of type C consistently led to semantic primary progressive aphasia.

15 ropsychological and neuroimaging features of primary progressive aphasia.

16 to verbal fluency and grammar impairment in primary progressive aphasia.

17 e left language network in logopenic variant primary progressive aphasia.

18 semantic memory deficit in semantic variant primary progressive aphasia.

19 subjects and patients with semantic variant primary progressive aphasia.

20 t the processing of non-verbal sounds in the primary progressive aphasias.

21 luent (n = 54) and semantic (n = 96) variant primary progressive aphasias.

22 in a consecutive series of 20 patients with primary progressive aphasia [12 with progressive non-flu

23 dementia, 14 patients with semantic variant primary progressive aphasia, 25 patients with Alzheimer'

24 hy, 4 subjects with the logopenic variant of primary progressive aphasia, 6 age-matched patients with

25 This study used patients with primary progressive aphasia, a clinical dementia syndrom

26 striking gains of function in a patient with primary progressive aphasia, a degenerative disease of t

27 analysed speech samples for 50 patients with primary progressive aphasia, along with neurodegenerativ

28 Patients with logopenic variant primary progressive aphasia also showed significant hype

29 frontotemporal dementia and semantic variant primary progressive aphasia (also called semantic dement

30 Patients with the semantic variant of primary progressive aphasia, also known as semantic deme

31 eed region derived from the semantic variant primary progressive aphasia analysis was strongly connec

32 5 years), 12 patients with logopenic variant primary progressive aphasia and 13 patients with posteri

33 Thirty-five patients with primary progressive aphasia and 29 control subjects were

34 We asked 15 patients with semantic variant primary progressive aphasia and 57 patients with Alzheim

35 We found that both semantic variant primary progressive aphasia and Alzheimer's disease are

36 We conclude that both semantic variant primary progressive aphasia and Alzheimer's disease are

37 Both semantic variant primary progressive aphasia and Alzheimer's disease had

38 Logopenic variant primary progressive aphasia and developmental dyslexia b

39 t tract underlies verbal fluency deficits in primary progressive aphasia and further confirm the role

40 However, recent primary progressive aphasia and normal neurophysiologica

41 n-verbal sound perception and recognition in primary progressive aphasia and specific disorders at pe

42 rior cortical atrophy than logopenic variant primary progressive aphasia) and higher-order visual net

43 bvFTD), 89 patients with semantic variant of primary progressive aphasia, and 30 patients with Huntin

44 tia, semantic variant and non-fluent variant primary progressive aphasia, and 46 healthy controls) de

45 89 patients (27.0%) with semantic variant of primary progressive aphasia, and 6 of 30 patients (20%)

46 osterior cortical atrophy, logopenic variant primary progressive aphasia, and corticobasal syndrome).

47 tegrity of these impacted neural networks in primary progressive aphasia are lacking.

48 characteristics of early and mild disease in primary progressive aphasia are poorly understood.

49 Revisions of criteria for logopenic primary progressive aphasia are proposed to address thes

50 Fifty-eight autopsies of patients with primary progressive aphasia are reported.

51 re the evolution of the logopenic variant of primary progressive aphasia as a distinct clinical entit

52 ed greater leftward asymmetry for tangles in primary progressive aphasia but not in the amnestic Alzh

53 nnected speech production in each variant of primary progressive aphasia, by quantifying speech outpu

54 A review of published primary progressive aphasia cases with adequate clinical

55 nships are not universal and that individual primary progressive aphasia cases with Alzheimer patholo

56 rnia San Francisco Memory and Aging Center's primary progressive aphasia cohort (n = 198) for history

57 ntactic comprehension in 51 individuals with primary progressive aphasia, composed of all clinical va

58 diagnoses included frontotemporal dementia, primary progressive aphasia, corticobasal syndrome, and

59 ortical atrophy and the logopenic variant of primary progressive aphasia, differ from amnestic AD in

60 0.001), while patients with semantic variant primary progressive aphasia discounted delayed rewards m

61 The Alzheimer's disease pathology in primary progressive aphasia displayed multiple atypical

62 in a consecutive series of 18 patients with primary progressive aphasia (eight with semantic variant

63 er neocortical-to-entorhinal tangle ratio in primary progressive aphasia establishes clinical concord

64 sive aphasia (nonfluent PPA; n = 15), fluent primary progressive aphasia (fluent PPA; n = 7), and amy

65 a core central auditory impairment exists in primary progressive aphasia for non-linguistic stimuli.

66 different to that seen in the fluent form of primary progressive aphasia (fPPA), a neurodegenerative

67 s for distinguishing the semantic variant of primary progressive aphasia from the partially overlappi

68 Moreover, patients with semantic variant primary progressive aphasia had a significantly more pro

69 Patients with primary progressive aphasia had deficits of non-verbal s

70 follow-up, all participants with non-fluent primary progressive aphasia had evolved either corticoba

71 of neurodevelopmental learning disability in primary progressive aphasia has been reported.

72 The connected speech of patients with primary progressive aphasia has often been dichotomized

73 ment before making a definitive diagnosis of primary progressive aphasia has promoted diagnostic spec

74 Observations in semantic variant primary progressive aphasia have inspired an alternative

75 Patients with logopenic and nonfluent primary progressive aphasia have some deficits recognizi

76 s been associated with syntactic deficits in primary progressive aphasia in a number of structural an

77 co-pathological relationships in subtypes of primary progressive aphasia in hopes of utilizing langua

78 We examined 39 patients with primary progressive aphasia including logopenic variant

79 Patient presenting with logopenic variant primary progressive aphasia initially thought to be due

80 Primary progressive aphasia is a clinical syndrome defin

81 Primary progressive aphasia is a clinical syndrome that

82 Primary progressive aphasia is a neurodegenerative clini

83 Primary progressive aphasia is a neurodegenerative syndr

84 Primary progressive aphasia is a syndrome characterized

85 icits may contribute to the phenomenology of primary progressive aphasia is not established.

86 irment for natural kinds in semantic variant primary progressive aphasia is related in part to diseas

87 y and executive deficits), logopenic variant primary progressive aphasia (language deficits), and pos

88 Patients with logopenic variant primary progressive aphasia ('language variant of Alzhei

89 Most subjects with logopenic variant of primary progressive aphasia (lvPPA) have beta-amyloid (A

90 n participants with the logopenic variant of primary progressive aphasia (lvPPA) performed a recognit

91 sterior cortical atrophy (PCA), 12 logopenic primary progressive aphasia (lvPPA), 20 behavioural vari

92 st that cortical atrophy in semantic variant primary progressive aphasia may follow connectional path

93 's disease, semantic dementia and non-fluent primary progressive aphasia (n = 9 each) were contrasted

94 ndrome, n = 13; behavioural variant, n = 14; primary progressive aphasias, n = 21) and 27 control sub

95 The non-fluent/agrammatic variant of primary progressive aphasia (naPPA) is a young-onset neu

96 ture of the non-fluent/agrammatic variant of primary progressive aphasia (naPPA), but well-controlled

97 hology in patients with nonfluent/agrammatic primary progressive aphasia (nfvPPA) and progressive sup

98 sive aphasia (svPPA), (4) non-fluent variant primary progressive aphasia (nfvPPA) or (5) early onset

99 phasia (svPPA), five with non-fluent variant primary progressive aphasia (nfvPPA)) and 17 healthy con

100 ed in difficulty, in patients with nonfluent primary progressive aphasia (nonfluent PPA; n = 15), flu

101 sed on larger groups of patients with either primary progressive aphasia or a typical amnestic dement

102 Cases with predominant primary progressive aphasia or extra-pyramidal syndromes

103 frontotemporal dementia and semantic variant primary progressive aphasia patients alone confirmed thi

104 odulated to a lesser extent or not at all in primary progressive aphasia patients whose syntax was re

105 tly limbic and symmetric pathology cause the primary progressive aphasia phenotype, characterized by

106 ral variant frontotemporal dementia (bvFTD), primary progressive aphasia (PPA) and corticobasal syndr

107 The dementia syndrome of primary progressive aphasia (PPA) can be caused by 1 of

108 Primary Progressive Aphasia (PPA) is a behaviorally foca

109 Primary progressive aphasia (PPA) is a clinical dementia

110 Primary progressive aphasia (PPA) is a clinical syndrome

111 Primary progressive aphasia (PPA) is a focal dementia ch

112 Primary progressive aphasia (PPA) is a neurodegenerative

113 Primary progressive aphasia (PPA) is a neurodegenerative

114 Primary progressive aphasia (PPA) is a progressive langu

115 Noninvasive brain stimulation in primary progressive aphasia (PPA) is a promising approac

116 Primary progressive aphasia (PPA) is an uncommon degener

117 Primary progressive aphasia (PPA) is characterized by an

118 The semantic variant of primary progressive aphasia (PPA) is characterized by th

119 Primary progressive aphasia (PPA) refers to a disorder o

120 diagnosis in a large cohort of patients with primary progressive aphasia (PPA) variants defined by cu

121 aging, and genetic study of 31 patients with primary progressive aphasia (PPA), a decline in language

122 Primary progressive aphasia (PPA), a selective neurodege

123 autopsy in up to one third of patients with primary progressive aphasia (PPA), but clinical features

124 In the nonfluent variant of primary progressive aphasia (PPA), degeneration of the p

125 D), amyotrophic lateral sclerosis (ALS), and primary progressive aphasia (PPA), including 281 AD, 256

126 In primary progressive aphasia (PPA), speech and language d

127 Impaired word retrieval is a main symptom of primary progressive aphasia (PPA).

128 hemisphere-dominant pattern of deposition in primary progressive aphasia (PPA).

129 est that syntactic comprehension deficits in primary progressive aphasia reflect not only structural

130 t language network for the logopenic variant primary progressive aphasia region of interest, and the

131 sion in the non-fluent/agrammatic variant of primary progressive aphasia relates to the strength of c

132 individual patients in both semantic variant primary progressive aphasia samples.

133 of atrophy in non-fluent/agrammatic variant primary progressive aphasia spreads over time from a syn

134 p that was matched in age and gender to each primary progressive aphasia subgroup (n = 20, age = 65 +

135 rity of white matter tracts in the different primary progressive aphasia subtypes.

136 ty had a predilection for one or more of the primary progressive aphasia subtypes.

137 The semantic variant of primary progressive aphasia (svPPA) is typically associa

138 al dementia (rtFTD), (3) semantic variant of primary progressive aphasia (svPPA), (4) non-fluent vari

139 ementia (bvFTD), eight with semantic variant primary progressive aphasia (svPPA), five with non-fluen

140 dementia, including the semantic variant of primary progressive aphasia (svPPA), is strongly associa

141 f resting state neuronal synchronizations in primary progressive aphasia syndromes.

142 patients with bvFTD and semantic variant of primary progressive aphasia than in those with AD and is

143 Within semantic variant primary progressive aphasia the right-handed and non-rig

144 operculum and caudate nucleus in non-fluent primary progressive aphasia (the corticobasal degenerati

145 These findings expand the differential of primary progressive aphasia to include prion disease.

146 yses related performance in semantic variant primary progressive aphasia to ventral and medial portio

147 istent region of atrophy in semantic variant primary progressive aphasia using cortical thickness ana

148 mage and syntactic deficits in patients with primary progressive aphasia, using multimodal neuroimagi

149 s of regional spectral power changes in each primary progressive aphasia variant, compared to age-mat

150 Each of the primary progressive aphasia variants showed different pa

151 trols showed significant differences between primary progressive aphasia variants themselves.

152 of network-specific neuronal dysfunction in primary progressive aphasia variants.

153 ntre of the non-fluent/agrammatic variant of primary progressive aphasia was derived in a group of 10

154 No subject with a diagnosis of primary progressive aphasia was identified with this mut

155 feature for all pathologies associated with primary progressive aphasia was the asymmetric prominenc

156 frontotemporal dementia and semantic variant primary progressive aphasia were most likely to exhibit

157 sis of patients with the semantic subtype of primary progressive aphasia, which is associated with ma

158 ntroversy were addressed in 72 patients with primary progressive aphasia who collectively displayed a

159 The association of logopenic primary progressive aphasia with Alzheimer's disease pat

160 ing research has associated semantic variant primary progressive aphasia with distributed cortical at

161 Behaviourally, patients with primary progressive aphasia with non-semantic subtypes w

162 ing in healthy controls and in patients with primary progressive aphasia with relatively spared synta

163 et Alzheimer's disease and logopenic variant primary progressive aphasia), with a trend towards lower

164 thology displays an atypical distribution in primary progressive aphasia yielded inconclusive results