ライフサイエンスコーパス: primary sensory neuron

1 control of the temporal responsiveness of a primary sensory neuron.

2 messages are initiated - at the level of the primary sensory neuron.

3 to a subset of Rohon-Beard cells, a type of primary sensory neuron.

4 despite both forms occurring within the AWC primary sensory neuron.

5 irect synaptic input from both pain and itch primary sensory neurons.

6 nt receptor potential vanilloid I (TRPV1) in primary sensory neurons.

7 spinal synapses made by axotomized group IA primary sensory neurons.

8 us particles in axons following infection of primary sensory neurons.

9 uired for efficient transcription of TrkA in primary sensory neurons.

10 e inhibitory effect of capsaicin on VACCs in primary sensory neurons.

11 isoforms are found only in a small subset of primary sensory neurons.

12 NSRs) are expressed solely in small diameter primary sensory neurons.

13 e-gated sodium channels present in motor and primary sensory neurons.

14 ion of nociceptor activity and plasticity of primary sensory neurons.

15 required simultaneously for survival of some primary sensory neurons.

16 expression, including frequent expression in primary sensory neurons.

17 a molecular integrator of painful stimuli on primary sensory neurons.

18 ch may be specific to a particular subset of primary sensory neurons.

19 t) mouse suffers from severe degeneration of primary sensory neurons.

20 important role in regulating excitability of primary sensory neurons.

21 m pepper family, which activates nociceptive primary sensory neurons.

22 erve injury on the regenerative state of the primary sensory neurons.

23 between neurotropic herpesviruses and murine primary sensory neurons.

24 el Nav1.8 is expressed almost exclusively in primary sensory neurons.

25 ervous system, including the spinal cord and primary sensory neurons.

26 Kv7.2 activity increases the excitability of primary sensory neurons.

27 nduction and maintenance of sensitization of primary sensory neurons.

28 led receptor expressed by a subpopulation of primary sensory neurons.

29 pression and function of Cavbeta subunits in primary sensory neurons.

30 nd murine TRPM8 channels, including those on primary sensory neurons.

31 s activates the D1-like dopamine receptor on primary sensory neurons.

32 d its ligand ephrinB2 in the dorsal horn and primary sensory neurons.

33 voltage-gated calcium and sodium currents in primary sensory neurons.

34 ally expressed in small-diameter nociceptive primary sensory neurons.

35 riety of receptors and channels expressed by primary sensory neurons.

36 iciency in coding that has not been found in primary sensory neurons.

37 Expression of Mtd promoted the death of primary sensory neurons, 293T cells and HeLa cells, indi

38 odium channels underlie hyperexcitability of primary sensory neurons after injury?

39 (BDNF), we developed an in vitro model using primary sensory neurons and a modified ELISA, termed ELI

40 They are expressed by primary sensory neurons and by glial cells in the centra

41 nish the resting membrane potential of mouse primary sensory neurons and cause cold-resistant hyperex

42 The lipid sensitizes TRPV1 ion channels in primary sensory neurons and causes increased frequency o

43 thesis of nonstructural proteins like KOR in primary sensory neurons and demonstrated a mechanism of

44 tion channel V1 (TRPV1) is also expressed in primary sensory neurons and detects painful stimuli such

45 unsaturated bonds, activate TRPA1 to excite primary sensory neurons and enteroendocrine cells.

46 ts high voltage-activated Ca(2+) channels in primary sensory neurons and excitatory synaptic transmis

47 alysis, metabolomics, and calcium imaging of primary sensory neurons and find no evidence of ligands

48 ted by hypochlorite and hydrogen peroxide in primary sensory neurons and heterologous cells.

49 and substance K, are produced in nociceptive primary sensory neurons and in many brain regions involv

50 Cbln2 expression tends to be more common in primary sensory neurons and in second-order sensory regi

51 that it is synthesized by subpopulations of primary sensory neurons and intrinsic spinal cord dorsal

52 (CePPEF) homolog is also highly expressed in primary sensory neurons and is not found outside the ner

53 avbeta(3) subunit augments HVACC activity in primary sensory neurons and nociceptive input to dorsal

54 he vertebrate embryo that gives rise to most primary sensory neurons and pigment cells in the adult o

55 s intracellular signaling molecules in these primary sensory neurons and provide a general mechanism

56 c proteins that are exclusively expressed in primary sensory neurons and provoke pain in humans.

57 tor) that decreases glucose-induced death of primary sensory neurons and reverses numerous clinical i

58 t the molecules that mediate chronic itch in primary sensory neurons and skin.

59 suggest that DOR-KOR heteromers exist in rat primary sensory neurons and that KOR antagonists can act

60 xtensive localization of the EP3 receptor in primary sensory neurons and the spinal cord.

61 e receptor 7 (TLR7) was expressed in C-fiber primary sensory neurons and was important for inducing i

62 olfactory abilities likely originates in the primary sensory neurons, and suggest that hormonal modul

63 In cultured primary sensory neurons, APDC blocked PGE2-induced poten

64 Dissociated primary sensory neurons are commonly used to study growt

65 Voltage-activated Na+ channels in the primary sensory neurons are important for generation of

66 isms mediating histamine-independent itch in primary sensory neurons are largely unknown.

67 Changes in primary sensory neurons are likely to contribute to the

68 Many primary sensory neurons are polymodal, responding to mul

69 This is what nociceptors do--these primary sensory neurons are specialized to detect intens

70 study, electrical stimulation of dissociated primary sensory neurons at 5 Hz, or treatment with eleva

71 At this longest survival, primary sensory neurons became infected.

72 In cultured rodent primary sensory neurons, BoNT-A decreased the proportion

73 he finding that VR1 is expressed not only in primary sensory neurons but also in several brain nuclei

74 , wheat germ agglutinin (WGA), is induced in primary sensory neurons, but only after transection of t

75 her increasing the intrinsic growth state of primary sensory neurons by a conditioning peripheral ner

76 SDHN following the activation of nociceptive primary sensory neurons by burn injury, capsaicin applic

77 in HEK293 cells, Xenopus laevis oocytes, and primary sensory neurons by measuring Ca(2+) signals.

78 Using these methods, primary sensory neurons can be transfected with an effic

79 from the peripheral and central terminals of primary sensory neurons can critically contribute to noc

80 ems unlikely that Ca2+ channel inhibition on primary sensory neurons can fully explain the behavioral

81 ity and/or increased baseline sensitivity of primary sensory neurons can lead to abnormal burst activ

82 In the rat, expression of PV by primary sensory neurons coincides with the onset of feta

83 otection against glucose-induced toxicity of primary sensory neurons compared to 2.

84 lation in injured dorsal root ganglion (DRG) primary sensory neurons consistent with an early phase o

85 How primary sensory neurons contribute to persistent pain re

86 Primary sensory neurons convey information from the exte

87 In vitro primary sensory neuron culture systems were subjected to

88 The peripheral terminals of primary sensory neurons detect histamine and non-histami

89 ctoderm and neural folds in the region where primary sensory neurons develop.

90 tion of voltage-sensitive Ca(2+) channels in primary sensory neurons (dorsal root ganglion) was diffe

91 Nociceptive primary sensory neurons endogenously express VR1, and re

92 ing molecules responsible for this change in primary sensory neuron excitability are still not well d

93 sts that substance P (SP) is up-regulated in primary sensory neurons following axotomy and that this

94 rat trigeminal ganglion, the location of the primary sensory neurons for face sensation, specific sil

95 Primary sensory neurons form the interface between world

96 ns, heat and anandamide were investigated in primary sensory neurones from neonatal rat dorsal root g

97 plitude of CXCL12-induced Ca(2+) response in primary sensory neurons from CCD mice was significantly

98 rent in prephenotype dorsal root ganglia and primary sensory neurons from dt mice, suggesting they ar

99 sitive fluorescent protein G-CaMP to map the primary sensory neurons governing avoidance to CO2.

100 Adult Wistar rat primary sensory neurons grown at physiological pH 7.4, t

101 However, the function of ERK2 in primary sensory neurons has not been directly tested.

102 Viral tracing of the circuits engaged by primary sensory neurons has, however, been hampered by t

103 cranial nerves (gV, gVII, gIV and gX) and in primary sensory neurons (i.e., Rohon-Beard neurons) in t

104 In cultured primary sensory neurons IL-31 triggered Ca(2+) release a

105 ognise the importance of ectopic activity in primary sensory neurones impinging on a sensitised centr

106 athways are segregated immediately after the primary sensory neuron in the chemotaxis circuit, and se

107 at induction of eIF2alpha phosphorylation in primary sensory neurons in a chronic inflammation pain m

108 DiI-labeling and immunostaining of primary sensory neurons in coculture revealed that these

109 restricted mainly to those subpopulations of primary sensory neurons in developing and adult DRGs tha

110 Motor neurons and primary sensory neurons in dorsal root ganglia had stron

111 TLR3 is expressed mainly by small-sized primary sensory neurons in dorsal root ganglions (DRGs)

112 e trigeminal ganglion cells are unique among primary sensory neurons in having two branches entering

113 ar effector, underlying the formation of any primary sensory neurons in higher vertebrates.

114 lly to transcriptional repression of MORs in primary sensory neurons in neuropathic pain.

115 roid hormones, targeted TRPA1 in peptidergic primary sensory neurons in rodent and human cells expres

116 m-CPP also decreased activity in primary sensory neurons in the crayfish.

117 ministered cisplatin (2 mg/kg i.p. for 5 d), primary sensory neurons in the dorsal root ganglion die

118 Primary sensory neurons in the DRG play an essential rol

119 imulus-evoked excitability in small diameter primary sensory neurons in the perinatal period and the

120 al mechanical origin of tactile information, primary sensory neurons in the trigeminal ganglion (Vg)

121 neurotoxin that destroys small unmyelinated primary sensory neurons in the vagus, as well as in othe

122 have demonstrated that anandamide can excite primary sensory neurons in vitro via transient receptor

123 We describe a model of gp120 toxicity to primary sensory neurons, in which gp120 induces neuritic

124 T, Ramsey, and T47D cells as well as that of primary sensory neurons, indicating that Diva is a proap

125 ct connections between the motor neurons and primary sensory neurons, indicating that further study w

126 uce robust axonal plasticity of normal adult primary sensory neurons into areas of transgene expressi

127 that sodium channel immunoreactivity within primary sensory neurons is dramatically increased within

128 r 1 TGR5 (encoded by GPBAR1) is expressed by primary sensory neurons; its activation induces neuronal

129 that the satellite glial cells that surround primary sensory neurons located in sensory ganglia of th

130 n (TTX)-resistant sodium channels present in primary sensory neurons may be responsible for the excit

131 Primary sensory neurons may constitute a final common pa

132 Sodium channels within primary sensory neurons may play an important role in th

133 ral side of the segmental ganglia, including primary sensory neurones, motoneurones and interneurones

134 eceptor VR1 is a cation channel expressed by primary sensory neurons of the "pain" pathway.

135 POU-domain transcription factor expressed in primary sensory neurons of the cranial and dorsal root g

136 report highly effective gene transfer to the primary sensory neurons of the dorsal root ganglia (DRGs

137 Since primary sensory neurons of the dorsal root ganglion show

138 Interestingly, a subset of primary sensory neurons of the ipsilateral trigeminal ga

139 ature olfactory sensory neurons (mOSNs), the primary sensory neurons of the olfactory epithelium.

140 expressed on olfactory sensory neurons, the primary sensory neurons of the olfactory epithelium.

141 The olfactory placodes generate the primary sensory neurons of the olfactory sensory system.

142 terminals of olfactory sensory neurons (the primary sensory neurons of the olfactory system, which p

143 tivating TRPA1, an excitatory ion channel on primary sensory neurons of the pain pathway.

144 l molecular detector of cold temperatures in primary sensory neurons of the somatosensory system.

145 s of these results under the assumption that primary sensory neurons of the trigeminal ganglion are s

146 edge of the neural plate become Rohon-Beard primary sensory neurons or neural crest.

147 axonal injury, concentrations of BH4 rose in primary sensory neurons, owing to upregulation of GCH1.

148 sfer is a feature shared by other classes of primary sensory neurons, permitting the identification a

149 Our findings suggest that MyD88 in primary sensory neurons plays an active role in regulati

150 These data indicate that the primary sensory neuron population and its projections ma

151 in controlling the intrinsic excitability of primary sensory neurons possibly via Ca(2+)-activated SK

152 When the axons of primary sensory neurons project into the embryonic mamma

153 nctional interactions in a sub-population of primary sensory neurons (PSN).

154 The peripheral axonal branch of primary sensory neurons readily regenerates after periph

155 The peripheral branch of primary sensory neurons regenerates after injury, but th

156 ular basis of mechanosensory transduction by primary sensory neurones remains poorly understood.

157 Thus, the primary sensory neurons responsive to beta-alanine are l

158 A recent study in primary sensory neurons shows that electrical activity--

159 Combining primary sensory neuron-specific GCaMP3 imaging with a tr

160 causative factor may be that only 50-60% of primary sensory neurons succeed in regenerating axons af

161 ) are present on the peripheral terminals of primary sensory neurons, suggesting that they might be i

162 t mustard oil depolarizes a subpopulation of primary sensory neurons that are also activated by capsa

163 We characterized the populations of primary sensory neurons that become latently infected wi

164 associated with inflammation and trauma, but primary sensory neurons that convey the sensation of acu

165 Thus, PKD1, PKD2, and PKD3 are expressed in primary sensory neurons that mediate neurogenic inflamma

166 rotrophic factor (BDNF) is expressed by many primary sensory neurons that no longer require neurotrop

167 dorants by olfactory sensory neurons (OSNs), primary sensory neurons that physically contact odor mol

168 f WNT/frizzled/beta-catenin signaling in the primary sensory neurons, the spinal dorsal horn neurons,

169 espite prominent expression of NMDARs in DRG primary sensory neurons, the unique role of peripheral N

170 Brn3a and Islet, which together characterize primary sensory neurons throughout the developing embryo

171 e have compared the membrane response of rat primary sensory neurons to capsaicin and noxious heat, u

172 ve protease-activated receptor 2 (PAR(2)) on primary sensory neurons to induce neurogenic inflammatio

173 t acts as a coincidence detector that allows primary sensory neurons to integrate information from ne

174 in sodium channel subunit Nav1.8-expressing primary sensory neurons, to examine the unique role of n

175 The principle by which unmyelinated primary sensory neurons transducing thermal, itch and pa

176 vents might also impact central processes of primary sensory neurons, triggering in nociceptors a hyp

177 effects were mediated by the transduction of primary sensory neurons via transport of FIV vectors fro

178 e and the frequency of transport in axons of primary sensory neurons were both reduced.

179 ive ligand-gated channel highly expressed in primary sensory neurons where it mediates nociception.

180 C(50) = 0.1 nm) and TRPA1 (IC(50) = 2 nm) in primary sensory neurons, whereas RvE1 and RvD1 selective

181 e spindles, taste buds, enteric neurons, and primary sensory neurons within the cranial and dorsal ro

182 nnections between cochlear sensory cells and primary sensory neurons, without loss of the sensory cel