ライフサイエンスコーパス: primary-cultured

1 The absence of apoE expression in primary cultured adipocytes also leads to changes in the

2 se regulation of mRNA expression, we treated primary cultured adipocytes for 18 h with insulin (25 ng

3 cts spanning this region, and tested them in primary cultured and immortalized cells.

4 In primary cultured aortic VSMCs, catalase and diphenylenei

5 LP isoforms were constitutively expressed by primary cultured articular chondrocytes, but only CILP-1

6 Primary cultured astrocytes (glial fibrillary acidic pro

7 Primary cultured astrocytes exposed to 5 mm NH4Cl for di

8 e release of preloaded [3H]-D-aspartate from primary cultured astrocytes prepared from the cerebral c

9 ound by the phosphorylated forms of CRYAB in primary cultured astrocytes, we show that there is clear

10 activated caspase 3 and induced apoptosis in primary cultured astrocytes, which was prevented by casp

11 alent cation-sensitive permeation pathway in primary cultured astrocytes.

12 enous RA and RA production (from retinol) in primary cultured astrocytes.

13 In primary cultured BBMEC, TNF exposure resulted in an incr

14 Our previous studies in primary cultured beta cells suggested the presence of a

15 TNF-alpha augmented the contraction of primary cultured bladder smooth muscle cells through upr

16 recombinant murine HIMF induced migration of primary cultured bone marrow cells that was completely b

17 meability was evaluated both in vitro, using primary cultured bovine brain microvessel endothelial ce

18 ession of the various MRP homologues in both primary cultured bovine brain microvessel endothelial ce

19 In the second experiment, primary cultured bovine corneal epithelial cells were tr

20 PDGF on proliferation and ECM production by primary cultured bovine keratocytes were evaluated.

21 ositol 4,5-bisphosphate (PIP2) levels in the primary cultured cardiomyocytes from adult rats.

22 In primary cultured cardiomyocytes, chronic inhibition of P

23 trate phosphorylation and calcium cycling in primary cultured cardiomyocytes.

24 amples and in CECs (IOBA-NHC cell line, n=3; primary cultured CEC, n=3) exposed to 10 ng/mL IL-1beta

25 nal NAADP-sensitive Ca(2+) stores in a human primary cultured cell type.

26 are present at readily detectable levels in primary cultured cells and are not upregulated following

27 ew studies have explored these mechanisms in primary cultured cells expressing endogenous levels of r

28 Experiments were also done ex vivo and with primary cultured cells in vitro.

29 RPE primary cultured cells of the monkey also showed beta-CM

30 n N40 to several immortalized cell lines and primary cultured cells, including endothelial cells and

31 the ability to extend the life-span of these primary cultured cells, this system would be useful for

32 ors blocked focal adhesion assembly in these primary cultured cells.

33 highly similar sequences, using protein from primary cultured cells.

34 (+) tumor cell lines but to be attenuated in primary cultured cells.

35 iption-polymerase chain reaction (RT-PCR) in primary cultured cells.

36 ion of cell surface beta PP and integrins in primary cultured cells.

37 ficiency virus type 1 produced in vivo or by primary cultured cells.

38 wth and pathogenesis in animal models and in primary cultured cells.

39 rt of 5-formyltetrahydrofolate (5-FTHF) into primary cultured cerebellar granule cells (CGC) was stud

40 , lambda, theta, and zeta are present in rat primary cultured cerebellar granule cells (CGCs) 6-14 da

41 ch reproducible results can be obtained with primary cultured CGCs in the study of PKC.

42 in both sense and antisense orientations, on primary cultured chick calvarial osteoblasts.

43 Uptake of L-carnosine by primary cultured conjunctival epithelial cells in the pr

44 Two conjunctival epithelial cell lines and primary cultured conjunctival epithelial cells were trea

45 potential usefulness of cryopreserved human primary cultured corneal endothelial cells by characteri

46 Human primary cultured corneal endothelial cells retain their

47 fficient and nontoxic to cryopreserved human primary cultured corneal endothelial cells.

48 UT3 surface expression and glucose import in primary cultured cortical and hippocampal neurons.

49 aired its sorting into processes of PC12 and primary cultured cortical neuronal cells.

50 alpha was targeted to processes in wild-type primary cultured cortical neurons and PC12 cells but fai

51 stribution of beta-tubulin isotypes in mouse primary cultured cortical neurons from embryonic fetus,

52 efficiency of human TAT-sEH variants in rat primary cultured cortical neurons, associated with incre

53 brain and rapid activation by CART of ERK in primary cultured cortical neurons.

54 examined the regulation of ERK5 signaling in primary cultured cortical neurons.

55 ng the neuroprotective actions of statins in primary cultured cortical neurons.

56 In contrast, immortalized and primary cultured cyst-lining epithelial cells from ADPKD

57 Moreover, primary cultured dopaminergic neurons from mesencephalon

58 Ninjurin2 promotes neurite outgrowth from primary cultured dorsal root ganglion neurons, presumabl

59 molecule and promotes neurite outgrowth from primary cultured DRG neurons.

60 We compared gene expression profiles of primary cultured ECs from human saphenous vein (SVEC) an

61 Primary cultured embryo fibroblasts from Gigyf2 null mic

62 Primary cultured endothelial cells and synoviocytes were

63 hence secretion of HCO(3)(-), we have loaded primary cultured endothelial cells derived from rat brai

64 R-126 upregulation increased angiogenesis of primary cultured endothelial cells from patients with de

65 Primary cultured endothelial cells from resistance arter

66 Primary cultured endothelial cells were dissociated from

67 he role of PDGF signaling in explant-derived primary cultured epicardial cells in vitro and in regene

68 In primary cultured esophageal epithelial cells, a region s

69 sufficient cell lines for a large scale HTS, primary cultured fibroblasts from MLD patients were tran

70 lls, but not in the nuclei of tumor cells or primary cultured fibroblasts.

71 HGFs were primary cultured from human gingiva specimens.

72 Approximately 5 to 20% of lung fibroblasts primary cultured from injured wild-type mice were green

73 P-43 to stress granules in Hek293T cells and primary cultured glia.

74 A human glioma cell line, U-87MG, and primary cultured glioblastoma cells (MG-377) overexpress

75 In primary cultured hASM cells taken from normal donors, CX

76 sion level between young and older donors in primary cultured HCECs.

77 We have used primary cultured hepatocytes from the rat to investigate

78 did not trigger Ca2+ oscillations in either primary cultured hepatocytes or hepatocytes within the i

79 phagy both in the in vivo mouse liver and in primary cultured hepatocytes.

80 uppressed by inhibition of the proteasome in primary cultured hepatocytes.

81 1 epitope is constitutively present in human primary cultured hepatocytes; however, its immunoreactiv

82 Using primary cultured HIMF-stimulated murine bone marrow cell

83 Using primary cultured hippocampal neurons (HNs) and rat pheoc

84 Most current methods of gene delivery for primary cultured hippocampal neurons are limited by toxi

85 Here, we were able to reproduce in primary cultured hippocampal neurons many of the effects

86 inhibitory postsynaptic currents (mIPSCs) in primary cultured hippocampal neurons, an effect opposite

87 brane pools, respectively, when expressed in primary cultured hippocampal neurons, consistent with pr

88 Primary cultured hRPE cells were incubated with various

89 Expression and activation of caspase-5 in primary cultured hRPE cells, telomerase-immortalized hTE

90 Primary cultured HSCs isolated from WT, SODmu, and NOX1

91 p53 genotype and occurs efficiently in some primary cultured human cells, indicating that the mutant

92 Primary cultured human corneal fibroblasts were exposed

93 studied in response to various treatments of primary cultured human esophageal epithelial cells and s

94 ssenger RNA (mRNA) and protein expression in primary cultured human hepatocytes, and stimulated MDR3

95 eta-inducible gene mRNA in HLE B-3 cells and primary cultured human lens cells from donor tissues.

96 The HLE B-3 cell line and primary cultured human lens cells respond similarly to T

97 d by both a human mast cell line (HMC)-1 and primary cultured human mast cells upon stimulation, wher

98 okines affect the degradation of Abeta using primary cultured human monocyte-derived macrophages (MDM

99 X2 is up-regulated in lungs, distal PAs, and primary cultured human PASMCs isolated from PAH and comp

100 Klotho protein (KL) is expressed in primary cultured human RPE, and regulates pigment synthe

101 cantly induced by all-trans-retinoic acid in primary cultured human tracheobroncheal epithelia.

102 me, is toxic to endothelial cells, including primary cultured human umbilical vein endothelial cells

103 Cryopreserved, primary, cultured human corneal endothelial cells are vi

104 We demonstrated here that primary cultured IMFs bind staphylococcal enterotoxins i

105 after T. gondii infection using isolated and primary cultured intestinal cells from infected mice and

106 ucose-responsive transcriptional enhancer in primary cultured islet cells and as a transcriptional re

107 otein complex that is found in the nuclei of primary cultured islet cells, but not in the nuclei of t

108 tically reduces sequencing error, to analyze primary cultured isolates phenotypically resistant to ri

109 imary mouse embryonic fibroblasts (MEFs) and primary cultured kidney cells from 6-8 month-old DNA-PKc

110 KT restored normal Na+/K+-ATPase activity in primary cultured lens cells and reduced lens pressure in

111 Primary cultured Lewis (RT1.A(l)) hepatocytes were trans

112 Primary cultured limbal epithelial cells were treated wi

113 Primary cultured lung fibroblasts prepared from both AT2

114 onstrate that monomeric Abeta degradation by primary cultured macrophages and microglia was significa

115 lated reporter-tagged Mbp mRNA granules from primary cultured mammalian oligodendrocytes to show that

116 FcepsilonRI-mediated signal transduction of primary cultured mast cells from Btk-, Lyn-, and Btk/Lyn

117 intestinal epithelial cell line), T84 cells, primary cultured mature human small intestinal epithelia

118 ion changes that occur during development of primary cultured megakaryocytes (MEG) and primary erythr

119 Accordingly, primary cultured microglia from CD45-deficient mice demo

120 In vitro, murine wild-type primary cultured microglia responded to synthetic dsRNA

121 myloid (Abeta) peptides, we first co-treated primary cultured microglia with a tyrosine phosphatase i

122 Further, FGF2 enhances Abeta phagocytosis in primary cultured microglia, and reduces Abeta production

123 Accordingly, primary cultured microglial cells from mice deficient in

124 0L-induced microglial activation, we treated primary cultured microglial cells with CD40L and anti-CD

125 cterized TDP-43 localization and dynamics in primary cultured motor neurons.

126 strong inhibitory effect on adipogenesis in primary cultured mouse ADSVFCs and human ADSCs.

127 We performed global expression profiling of primary cultured mouse and human macrophages, sampling a

128 Fabry disease, the caveolar lipid content of primary cultured mouse aortic endothelial cells isolated

129 and 1-120 amino acid N-terminal peptides in primary cultured mouse astrocytes.

130 expression profile of their synthases in the primary cultured mouse bone marrow derived macrophages (

131 These fusion proteins were expressed in primary cultured mouse brain astrocytes and arterial smo

132 n that store-operated Ca(2+) entry (SOCE) in primary cultured mouse cortical astrocytes occurs at pla

133 ve role against APAP-induced hepatotoxicity, primary cultured mouse hepatocytes and green fluorescent

134 In primary cultured mouse hepatocytes and HepG2 cells, the

135 various essential autophagy-related genes in primary cultured mouse hepatocytes and in mouse liver.

136 crosis factor alpha (TNFalpha) and sensitize primary cultured mouse hepatocytes to TNF-mediated apopt

137 en-induced necrotic and apoptotic killing of primary cultured mouse hepatocytes.

138 man HepaRG cells, rodent in vivo models, and primary cultured mouse hepatocytes.

139 Furthermore, primary cultured mouse motor neurons showed axonal degen

140 we examined PLN stability and degradation in primary cultured mouse neonatal cardiomyocytes (CMNCs) a

141 tected BID in the cytosol of mouse brain and primary cultured mouse neurons and demonstrated, by usin

142 In primary cultured mouse PASMCs loaded with fura-2, cyclop

143 The effects of supernatants from primary cultured mouse podocytes, before or after sublet

144 ocal measurements of intracellular Ca(2+) in primary cultured mouse skeletal myotubes reveal active s

145 AVP stimulated GLP-1 and PYY release from primary cultured murine and human colonic cells and was

146 ctivin betaA mRNA was also highly induced in primary cultured murine bone marrow MC (BMMC) after stim

147 of TRAIL on IL-33 expression was assessed in primary cultured murine hepatocytes.

148 evels increased 10-fold within 24-48 h after primary cultured muscle cells; C2C12 mouse myoblasts or

149 We show that in primary cultured myocytes most of the RAS is localized t

150 Studies were conducted in primary cultured myotubes from beta1 knockout (KO), ryan

151 croscopy was used to monitor Ca2+ signals in primary-cultured myotubes, prepared from forelimbs of wi

152 ety of neuronal cell lines (PC12, GT1-7) and primary cultured neurons (hippocampal, cortex).

153 microglia, and reduces Abeta production from primary cultured neurons after AAV2/1-FGF2 infection.

154 N1 protected primary cultured neurons against toxicity and cell death

155 We have replicated this observation in primary cultured neurons and demonstrate, by the accumul

156 d enhances aggregation of alpha-synuclein in primary cultured neurons and in dopaminergic neurons of

157 Here we demonstrate, in primary cultured neurons and the N2a neural cell line, t

158 y lower doses than those usually observed in primary cultured neurons and vascular smooth muscle cell

159 ated oxidative stress-mediated cell death in primary cultured neurons at nanomolar concentrations.

160 ta load in neuroblastoma cells as well as in primary cultured neurons derived from Tg2576 mice.

161 sease by 20 months of age, ALS2(-/-) mice or primary cultured neurons derived from these mice were mo

162 ke ibuprofen, promotes neurite elongation in primary cultured neurons exposed to axonal growth inhibi

163 HEK293) cells stably expressing the CB1R and primary cultured neurons expressing endogenous CB1R, we

164 t ubiquitination of endogenous Bax comparing primary cultured neurons from WT and parkin KO mice and

165 owever, the regulatory properties of ERK5 in primary cultured neurons have not been reported.

166 us (AAV) vectors for genetic manipulation of primary cultured neurons in vitro.

167 We show that increased E6AP expression in primary cultured neurons leads to a reduction in dendrit

168 ions for problems encountered when utilizing primary cultured neurons to study PKC-mediated signal tr

169 Furthermore, in primary cultured neurons, a proportion of UCH-L1(M) does

170 o mammalian-cultured cells, yeast, bacteria, primary cultured neurons, Drosophila melanogaster larval

171 In primary cultured neurons, NES mutations increase nuclear

172 l lines and trains of action potentials from primary cultured neurons.

173 t reticulocyte lysates, Xenopus oocytes, and primary cultured neurons.

174 This hypothesis was tested on primary cultured neurons.

175 he secretion of neurotoxic factors that kill primary cultured neurons.

176 entiated PC12 cells or serum withdrawal from primary cultured neurons.

177 tide in multiple mammalian cell lines and in primary cultured neurons.

178 vation and reduced spine density and size in primary cultured neurons.

179 displayed activity in several cell lines and primary cultured neurons.

180 we performed a proteomic comparison between primary-cultured NPCs from the young adult and aged mous

181 Infection of primary cultured PASMCs with an adenoviral vector expres

182 Uptake of the dipeptide L-carnosine in primary cultured pigmented rabbit conjunctival epithelia

183 e have developed an in vitro BBB model using primary cultured porcine brain endothelial cells (PBECs)

184 slices from PS conditional knockout mice and primary cultured postnatal hippocampal neurons, in which

185 examine the expression of messenger RNAs in primary cultured rabbit and human lens cells and in ex v

186 -induced oxidant stress were investigated in primary cultured rabbit conjunctival epithelial cells (R

187 o define transport characteristics of GSH in primary cultured rabbit conjunctival epithelial cells (R

188 ivity in rabbit corneal epithelial (RCE) and primary cultured rabbit corneal epithelial (PRCE) cells

189 Primary cultured rabbit esophageal cells were loaded wit

190 are capable of inducing CYP3A expression in primary cultured rat and mouse hepatocytes and that the

191 ivity in transient transfection assays using primary cultured rat aortic SMCs.

192 sine kinase induces MMP-9 expression in both primary cultured rat aortic smooth muscle cells and in a

193 of the inducible NOS 5'-flanking region into primary cultured rat aortic smooth muscle cells and stim

194 gh levels of luciferase reporter activity in primary cultured rat aortic smooth muscle cells, and thi

195 niques to localize alpha subunit isoforms in primary cultured rat astrocytes, neurons, and arterial m

196 s a correlation of apoD's ability to protect primary cultured rat cardiomyocytes from hypoxia/reoxyge

197 In primary cultured rat cardiomyocytes, phenylephrine-induc

198 Primary cultured rat cerebellar granule neurons underwen

199 , potentiation and inhibition, on nnAChRs in primary cultured rat cortical neurons.

200 ssed with green fluorescent protein (GFP) in primary cultured rat dorsal root ganglion neurones (DRGs

201 re examined on cytochrome P450 expression in primary cultured rat hepatocytes and rat liver.

202 In vitro studies in primary cultured rat hepatocytes show that nontoxic conc

203 0/41) gene transcription was investigated in primary cultured rat hepatocytes transiently transfected

204 ted CYP3A mRNA induction was eliminated when primary cultured rat hepatocytes were cotreated with any

205 Primary cultured rat hepatocytes were transfected with s

206 Primary cultured rat hepatocytes were used to explore ke

207 eptor (PXR)-null mice, and cotransfection of primary cultured rat hepatocytes with a dominant-negativ

208 teric small arteries, and Ca2+ signalling in primary cultured rat hippocampal neurones.

209 cally transfected with ERalpha or ERbeta, in primary cultured rat hippocampal neurons in vitro and in

210 lysis, we have demonstrated the inability of primary cultured rat hippocampal neurons to induce a hea

211 tion of a heteromeric TRPV4-C1-P2 complex in primary cultured rat mesenteric artery endothelial cells

212 ent and inward Ca2+ current were recorded in primary cultured rat myoballs using the whole-cell confi

213 ines, and during in vitro differentiation of primary cultured rat oligodendrocytes.

214 dependently up-regulated TRPC6 expression in primary cultured rat PASMCs, and this was accompanied wi

215 nases (CDKs), Cdk2, Cdk3, Cdk4, and Cdk6, in primary cultured rat superior cervical ganglion sympathe

216 m apical fluid was significantly elevated in primary cultured RCECs treated for 24 hours with various

217 ) was examined after a 24-hour incubation of primary cultured RCECs with an NO donor, S-nitroso-N-ace

218 Kir2.3 inward rectifier K(+) channel in rat primary cultured reactive astrocytes.

219 Both immortalized and primary cultured renal epithelial cells that originate f

220 played a robust and punctate distribution in primary cultured retinal amacrine cells known to form ex

221 In primary cultured rodent and human macrophages, CB1R acti

222 Using primary cultured Schwann cells, we analyze the upstream

223 Using primary cultured Sertoli cells as an in vitro model that

224 - tagged nebulin fragments were expressed in primary cultured skeletal myotubes.

225 on in modulating the level of PPIX, in human primary cultured skin fibroblasts (FEK4) maintained eith

226 demonstrated that CD28 was also expressed by primary-cultured stromal cells that supported B lymphopo

227 o cells (a placental-trophoblast cell line), primary cultured trophoblasts, and human umbilical-vein

228 gnant human myometrial cell line PHM1-41 and primary cultured uterine myocytes responded to Toll-like