ライフサイエンスコーパス: primitive

1 molecules in host cells and tissues remains primitive.

2 of population-level representations remains primitive.

3 p to 200 qubits containing the computational primitive.

4 g to demonstrate that number is a conceptual primitive.

5 t our hypothesis that the OCP2 is relatively primitive.

6 Seeds of a primitive accession (PI251246) of lettuce exhibited high

7 melt is provided by X-ray microtomography of primitive achondrite Northwest Africa (NWA) 2993.

8 ative core formation in the parent bodies of primitive achondrites.

9 s in these regions are not reducible to more primitive affective dimensions such as valence and arous

10 d expansion of the distal lung saccules into primitive alveoli.

11 fying a dramatic change in the physiology of primitive AML cells when the disease progresses.

12 is membrane network is conserved in maturing primitive and definitive erythroblasts despite their res

13 oietic ontogeny is characterized by distinct primitive and definitive erythroid lineages.

14 n of mouse embryonic stem (ES) cells to both primitive and definitive haematopoietic cells.

15 iety of dental characters with both the most primitive and derived members of the subfamily.

16 We conclude that Erf is required for both primitive and erythromyeloid progenitor waves of hematop

17 The mechanical behavior of primitive and gyroid schwartzite structures across diffe

18 Thus, M. hirta with a combination of primitive and more derived characters highlights its tra

19 herapy compared with subfractions displaying primitive and quiescent signatures.

20 r neurons that direct undulatory swimming in primitive aquatic vertebrates, permitting assessment of

21 ti-dimensional tasks in which a set of fixed primitives are each able to compensate for errors in a s

22 other nitrogenous species formed in Earth's primitive atmosphere.

23 rily caused by a demyelination rather than a primitive axonal damage.

24 istry shows that differentiation trends from primitive basaltic to felsic compositions for volcanic v

25 ithines supports the interpretation of these primitive birds as competent fliers.

26 Expressing those primitive bona fide CHIs in the Arabidopsis chi mutant r

27 es that constitute a good model for studying primitive brain features, most likely present in the anc

28 on effects on offspring LTL in Soay sheep, a primitive breed experiencing strong sperm competition.

29 This complex secondary structure serves as a primitive but highly effective strategy for the thermal

30 c computing, despite its novel architectural primitives, can implement deep convolution networks that

31 somatic equivalents of blastomeres, the most primitive cancer stem cells reported to date.

32 monolayer and organization of the cells into primitive capillary-like assemblies in 3D sea sponge sca

33 The Notch signaling pathway is crucial for primitive cardiac valve formation by epithelial-mesenchy

34 quiescent CD34(+)Hoescht(-)Pyronin Y(-) and primitive CD34(+)38(-), as compared with proliferating C

35 Here, we show that primitive (CD34(+)CD38(-)) CML cells, in contrast to cor

36 of these contains five formula units in the primitive cell and has C2/m symmetry (5FU-C2/m).

37 could have driven the growth and division of primitive cell membranes.

38 ne or two lithium atoms are extracted from a primitive cell of LZO, its volume and structure change l

39 ) for delithiation of the first Li atom in a primitive cell, which is confirmed by galvanostatic char

40 s that direct proper cell gene expression in primitive cells and their differentiating progeny.

41 One widely held model of early life suggests primitive cells consisted of simple RNA-based catalysts

42 d output in vitro and in xenografted mice of primitive cells with an enhanced ability to differentiat

43 d existence of an autocrine loop promote CML-primitive cells' TKI resistance.

44 iotic earth may have led to the emergence of primitive cells.

45 etwork topologies within their corresponding primitive cells.

46 de confinement could have been important for primitive cellular evolution.

47 onic stem cells, thereby phenocopying a more primitive cellular state.

48 therto unobserved combination of derived and primitive character states.

49 dies are chemically fractionated compared to primitive, chondritic meteorites and, by inference, the

50 Microvillar photoreceptors of the primitive chordate amphioxus also express melanopsin and

51 In a primitive chordate model of natural chimerism, one chime

52 are also present in Nematodes, Cnidaria and primitive chordates, this method could also have high po

53 with functional assays, we demonstrate that primitive CML cells rely on upregulated oxidative metabo

54 here they are required for remodeling of the primitive coronary plexus.

55 This contrasts with primitive CP-CML cells and BCR-ABL1-negative acute myelo

56 charged phase changes the structure from the primitive cubic ([Formula: see text]) to the double diam

57 report water vapor sorption studies on four primitive cubic, pcu, pillared square grid materials: SI

58 In this state, GSCs upregulate primitive developmental programs and are dependent upon

59 velopment has been considered to reflect the primitive dinosaurian condition.

60 sect the cell entry mechanism of GLV into a "primitive" (early-branching) eukaryotic host and an impo

61 rited from metal-silicate differentiation in primitive Earth and depend upon the nature of physiochem

62 pt posits that there was a period of time in primitive Earth's history - about 4 billion years ago -

63 oose GAC particles and slow kinetics of this primitive electrode necessitated improvements.

64 ation of immature smooth muscle cells in the primitive embryonic dorsal aorta establishes the long-li

65 hanism to ensure the progressive assembly of primitive embryonic tissues.

66 ll mass (ICM), followed by epiblast (EPI) or primitive endoderm (PE) specification within the ICM.

67 , which will form the new organism, from the primitive endoderm (PE), which will form the yolk sac, i

68 decision between the epiblast (Epi) and the primitive endoderm (PrE) fate that occurs in the mammali

69 by-stage analysis of EPI and extra-embryonic primitive endoderm (PrE) formation during preimplantatio

70 ) is the key signal driving specification of primitive endoderm (PrE) versus pluripotent epiblast (EP

71 EPI), which forms the embryo proper, and the primitive endoderm (PrE), which forms extra-embryonic yo

72 the inner cell mass and the formation of the primitive endoderm (PrE).

73 (ICM) can be specified in epiblast (Epi) or primitive endoderm (PrE).

74 contain precursors of the epiblast (Epi) and primitive endoderm (PrEn) lineages.

75 is abundantly expressed in trophectoderm and primitive endoderm cells of human blastocyst-stage embry

76 a2/FOXA2, which we show is restricted to the primitive endoderm in both human and mouse embryos.

77 ied in silico precursors of the epiblast and primitive endoderm lineages and revealed a role for MCRS

78 show that a consistent ratio of epiblast and primitive endoderm lineages is achieved through incremen

79 t are derived from the trophectoderm and the primitive endoderm upon reintroduction to the blastocyst

80 l lineages in the blastocyst: trophectoderm, primitive endoderm, and epiblast.

81 stigating the interstellar medium at a quasi-primitive environment in the early universe.

82 his ES cell line, we observed that the first primitive erythroblasts are detected in vitro around day

83 Primitive erythroblasts are the first blood cells genera

84 f resulted in both reduced and more immature primitive erythroblasts at E9.5 to E10.5.

85 We found that primary primitive erythroblasts express the major membrane skele

86 .1 R isoform switching and protein 4.1R-null primitive erythroblasts fail to establish normal membran

87 We conclude that maturing primitive erythroblasts initially navigate the embryonic

88 distribution, maturation, and enucleation of primitive erythroblasts were also impaired by Vegfc dele

89 Membrane deformability and stability of primitive erythroblasts, assayed by microfluidic studies

90 and composition of the membrane skeleton in primitive erythroblasts, which progressively mature whil

91 s demonstrate that both in vivo and in vitro primitive erythrocytes are generated from hemogenic endo

92 EGF-C loss did not disrupt the generation of primitive erythroid cells or erythro-myeloid progenitors

93 H1 hemoglobin gene expressed specifically in primitive erythroid cells.

94 use model and demonstrated the presence of a primitive erythroid primed hemogenic endothelial cell po

95 ement Gfi1 depletion phenotypes in zebrafish primitive erythropoiesis and granulocytic differentiatio

96 ion in vivo with increased commitment toward primitive erythropoiesis in Foxf1-deficient embryos, whe

97 oiesis and definitive hematopoiesis, but not primitive erythropoiesis or vasculogenesis.

98 Having no apparent effect on primitive erythropoiesis, FLKO mice show significant enh

99 To selectively investigate primitive erythropoiesis, we have engineered a new trans

100 feature not only of definitive, but also of primitive, erythropoiesis in mammals.

101 to have evolved in North America from a more primitive Eurasian immigrant.

102 xiety may indicate underlying dysfunction in primitive fear conditioning circuits in the cerebellum.

103 e that shedding involved tooth resorption, a primitive feature in bony fishes, but absent in sharks a

104 Within the context of primitive features found elsewhere in the skeleton, thes

105 HSC and may provide new tools to manipulate primitive features in HSC for clinical applications.

106 polypterid branch and expose many supposedly primitive features of extant polypterids as reversals.

107 ganization of the nitrergic system from this primitive fish group to amniotes, including mammals.

108 RH) and urocortin1/urotensin1 (UCN1/UTS1) in primitive fishes, teleosts, and tetrapods.

109 uggests that internal fertilization could be primitive for gnathostomes, but such a conclusion depend

110 s have enabled realizations of the necessary primitives for quantum information processing and the hi

111 At the protein level, starting with a primitive form in cyanobacteria, RCA of chlorophytes evo

112 Here we report a primitive form of artificial phagocytosis in a binary co

113 trumental in the origin of life by driving a primitive form of self-replication through fragmentation

114 The study of primitive fossil insect nymphs has revealed that wings d

115 well as SWEETs and a potential SemiSWEET in primitive fungi.

116 s revealed the two terpene synthase genes as primitive genes that might have evolved from an ancestra

117 ay from the neural tube toward and along the primitive gut.

118 tage-specific markers highlighted defects of primitive haematopoiesis and traced back the dramatic re

119 haemogenic endothelium, which only produced primitive haematopoietic progenitors.

120 The most primitive heart system of the Drosophila provides a usef

121 line, where they meet and fuse to create the primitive heart tube.

122 ckdown does not affect erythropoiesis during primitive hematopoiesis (no effect on gata1 or h-bae1) o

123 s required in both ectoderm and mesoderm for primitive hematopoiesis to occur.

124 blast markers, etsrp, fli1a, and scl; blocks primitive hematopoiesis, as shown by decreased expressio

125 One is derived from primitive hematopoiesis, with no interchange by blood ce

126 into the DH GRN and the HE, as well as into primitive hematopoiesis.

127 te whether the absence of ATMIN would affect primitive hematopoietic cells in an ATM-dependent or -in

128 ive DNA damage, is compromised in Foxo3(-/-) primitive hematopoietic cells.

129 mesoderm and WNT-independent KDR(+)CD235a(+) primitive hematopoietic mesoderm revealed strong CDX gen

130 ecification resulted in a >90% repression in primitive hematopoietic potential, but conferred fivefol

131 In contrast, CDX4 knockout hPSCs had intact primitive hematopoietic potential, but exhibited a fivef

132 11A), which functions as a growth factor for primitive hematopoietic progenitor cells.

133 3 leads to the accumulation of DNA damage in primitive hematopoietic stem and progenitor cells (HSPC)

134 odel to transfer genes specifically into the primitive hematopoietic stem cell compartment through th

135 ely alters the functional characteristics of primitive hematopoietic stem/progenitor cells (HSPCs) co

136 This simple physical system enables a primitive homeostatic behaviour: the maintenance of cons

137 Homo floresiensis, a primitive hominin species discovered in Late Pleistocene

138 e results demonstrate that a morphologically primitive hominin, Homo naledi, survived into the later

139 Next, a primitive homolog of nitrogenase mediates a six-electron

140 r of JAK-STAT pathways, is expressed in most primitive HSC and is upregulated in response to STAT5-in

141 om radiation injury with concomitant loss of primitive HSCs.

142 The percentage of GFP-expressing primitive HSPCs capable of forming multilineage progenit

143 proach allows for the stable transduction of primitive HSPCs.

144 vents that 5 GFs elicit directly in the most primitive human hematopoietic cell types to promote thei

145 ds and either of face-centred-icosahedral or primitive-icosahedral type, and the positions of their a

146 crete and low-dimensional control that these primitives imply.

147 l implications reveal five oleosin lineages: primitive (in green algae, mosses, and ferns), universal

148 s such as "fear" or "anxiety." These emotion primitives include scalability, persistence, valence, an

149 The more primitive innate immune system of insects has also been

150 ment control, but whether it actually stores primitives instead of computing solutions on the fly to

151 reaches of sensory processing and even that primitive internal affective dimensions (e.g., goodness-

152 escales, spiking activity in an evolutionary primitive (koniocellular) LGN pathway is specifically li

153 phosphorylation in AML cells and suppresses primitive leukemic progenitors from AML patients in vitr

154 lution (especially in the early evolution of primitive life) and (ii) interoceptive mechanisms could

155 ve played a key role in early life, and that primitive lipid membranes and encapsulated catalysts, su

156 a, previously identified as an exceptionally primitive lobe-finned fish [3, 7, 11, 12].

157 receptor as a potential target to eradicate primitive LSCs in AML.

158 lunar carbon and S isotopic compositions of primitive lunar materials.

159 eration ability and increased maintenance of primitive markers in vitro in both liquid and OP9-DeltaL

160 with a striking pattern of dark areas termed primitive markings.

161 in water deer (Hydropotes inermis, the most primitive member of the family Cervidae), reindeer (Rang

162 tly, Chororapithecus abyssinicus, a probable primitive member of the gorilla clade, was discovered fr

163 at Lats1/2 kinases suppress expansion of the primitive mesenchymal progenitors, where YAP activation

164 Deltatheroidans are primitive metatherian mammals (relatives of marsupials),

165 depletion of bulk silicate Earth relative to primitive meteorites is consistent with the depletion of

166 uds, and, more importantly, in comets and in primitive meteorites that have most probably seeded the

167 ompare these two methods, while also using a primitive method without BSSVS, and highlight the differ

168 icles with aqueous microcompartments to form primitive microreactors.

169 cervates were also formed on silica beads, a primitive model for localization at specific intracellul

170 In the 36 years since the first primitive model of the red cell skeleton was proposed, m

171 ze under certain conditions than the GLMs or primitive models, and believe that the connection betwee

172 the sublimation/condensation temperatures of primitive molecules, we suggest that organic ices and ma

173 of negatively charged calcium atoms, and the primitive monoclinic phase (space group P21/c) of CaC wi

174 se of genetically manipulating and assessing primitive mouse hematopoietic cells, has made this speci

175 icroglia-specific genes that were induced in primitive mouse macrophages after migration into the fet

176 esents a transitional morphology between the primitive, multivalvar, conal condition and the derived,

177 d tfpi form a regulatory axis that specifies primitive myelopoiesis and definitive hematopoiesis, but

178 otential mechanism by which adtrp1 regulates primitive myelopoiesis and definitive hematopoiesis.

179 fpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis.

180 invertebrate-like channels, which we termed primitive myxoid vascularization.

181 ation and fusion of the cylinders results in primitive nanosheets that are stabilized by the thicker

182 In a human NTera2 cell model of primitive neural stem cells carrying resting cytomegalov

183 escently infected human NTera2 cell model of primitive neural stem cells, we found that costimulation

184 preventing the invasion of microtubules into primitive neurites, which can be rescued by the knockdow

185 Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are

186 r recent anatomically modern humans and more primitive neurocranial and endocranial morphology.

187 s of medulloblastoma, central nervous system primitive neuroectodermal tumor (PNET), and astrocytoma

188 nd those without a bone sarcoma (ie, neither primitive neuroectodermal tumor nor osteosarcoma) (HR fo

189 ie, atypical teratoid/rhabdoid tumor and CNS primitive neuroectodermal tumor).

190 rs (16 osteosarcomas, one Ewing sarcoma, one primitive neuroectodermal tumor, and one desmoplastic sm

191 iction should raise the suspicion of a renal primitive neuroectodermal tumor, in a young adult.

192 Primary renal primitive neuroectodermal tumor/extraskeletal Ewing's sa

193 Primitive neuroectodermal tumors of the central nervous

194 Cs were transformed with N-Myc, we generated primitive neuroectodermal tumors with divergent differen

195 s inactivation of RBP-Jkappa and p53 induces primitive neuroectodermal-like tumors in mice.

196 e we show that macrophages structurally form primitive, NON-ENDOTHELIAL "vessels" or vascular mimicry

197 In the primitive noncoding ribosome, proto-mRNA and the small r

198 Furthermore, neither primitive nor evolved hydrated Martian crust show notice

199 remyella diplosiphon and the presumably more primitive OCP2 paralog from the same organism, we show t

200 tanglement distillation on a quantum network primitive of distant electron-nuclear two-qubit nodes.

201 The most primitive of the stem/progenitor cells, biliary tree ste

202 Primitive oleosins already possess all the general chara

203 a expression, mesoderm harboring exclusively primitive or definitive hematopoietic potential to under

204 which may consist of internal models, motor primitives or motor synergies.

205 Nd-Pb abundances and isotope ratios that the primitive Oraefajokull melts could have assimilated 2-6%

206 ces in carbonaceous, enstatite, Rumuruti and primitive ordinary chondrites are about 6 times, 9 times

207 Many bacteria contain primitive organelles composed entirely of protein.

208 In the nascent solar system, primitive organic matter was a major contributor of vola

209 However, the origin of primitive organics is poorly understood.

210 ntal and isotopic fractionations observed in primitive organics.

211 lear receptors are encoded in the genomes of primitive organisms that lack endocrine signaling, sugge

212 l soup, when properly cooked, was edible for primitive organisms.

213 d (SHF) give rise to the right ventricle and primitive outflow tract (OFT).

214 mall node of cells in the medulla - the most primitive part of the brain - may function to control RE

215 -doped SrFe0.9Nb0.1O3-delta finding that the primitive perovskite oxide SrFe0.8Cu0.1Nb0.1O3-delta (SF

216 characterized, the reactions present in the primitive peroxisomes (microbodies) of algae are poorly

217 The latter appear to be analogous to the primitive placenta formed during implantation.

218 erated endothelial cells rapidly expand into primitive plexi that undergo vascular remodeling into ci

219 nder low flow conditions that prevail in the primitive plexus.

220 internal state exhibiting canonical emotion primitives, possibly analogous to fear in mammals.

221 etween 'modern' picornaviruses and the more 'primitive' precursor insect viruses; for instance, HAV r

222 the normal population that contains stem and primitive progenitor cells.

223 mpartmentalization of inorganic catalysts in primitive protocells.

224 Furthermore, we demonstrate that the most primitive quiescent HSPCs are more resistant to spontane

225 The primitive red blood cells were enlarged, poikilocytic, a

226 are now describing infants with exaggerated primitive reflexes, epilepsy, acquired hydrocephalus and

227 Reactivating primitive reparative ability in the mature mammalian hea

228 morphology between archosauriforms and more primitive reptiles.

229 Forstercooperiines are a group of primitive rhinocerotoids with a relatively large body si

230 igns are presented where, quadratic residue, primitive root and ternary sequence diffusers are mimick

231 Ewing sarcoma is a primitive round cell sarcoma with a peak incidence in ad

232 Primitive semi-organized lymphoid nodules or aggregates

233 The primitive signaling scheme used in access networks enabl

234 ing normal development, highlight the likely primitive skeletogenic potential of this cell population

235 about 248 million years ago) of China, whose primitive skeleton indicates possible amphibious habits.

236 Asteroids are primitive Solar System bodies that evolve both collision

237 Lecithoepitheliata have primitive spiral cleavage but derived ectolecithal eggs.

238 ntially in artery, vein, capillaries and the primitive sprouting front.

239 miRNA, but quantification pipelines are in a primitive stage and still evolving; there are many facto

240 c and spatiotemporal aspects at a relatively primitive stage.

241 pithelium is transiently reprogrammed into a primitive state.

242 ucleoprotein (mRNP) components to ensure the primitive status of SSCs through a dual mechanism that i

243 ctinellid spicule homology, and supports the primitive, stem-silicean interpretation of simpler-struc

244 The left wall of the primitive stomach expands more than the right wall, as t

245 ion in the anterior visceral endoderm (AVE), primitive streak (PS) and definitive endoderm (DE) have

246 NMPs are known to reside in the anterior primitive streak (PS) region; however, the extent to whi

247 tically alters anteroposterior patterning of primitive streak (PS)-like priming.

248 tion, which is initiated by formation of the primitive streak (PS).

249 E-cadherin needs to be downregulated in the primitive streak and in the epiblast, concomitant with t

250 ting that loss of pluripotency, formation of primitive streak and mesodermal lineage progression are

251 Zeb2 repress P-cadherin transcription in the primitive streak and the neural plate, respectively.

252 migration of nascent mesodermal cells in the primitive streak as the morphogenetic basis underlying t

253 initiates a process that resembles posterior primitive streak development in a SNAI1-dependent manner

254 trulation, when cells ingressing through the primitive streak differentiate into the precursor cells

255 n and avian embryos is the appearance of the primitive streak in the future posterior region of a rad

256 The primitive streak marks the midline of the future embryo.

257 leads to gastrulation phenotypes, including primitive streak patterning defects in association with

258 e mechanisms responsible for positioning the primitive streak remain largely unknown.

259 n is weakly expressed in the epiblast at pre-primitive streak stages where it is substituted for by P

260 ranscription factor that is expressed in the primitive streak, mesoderm and anterior mesendoderm of t

261 We propose that these cells arise within primitive streak-associated epiblast via a mechanism tha

262 rcation event early in the trajectory when a primitive streak-like cell population segregated into th

263 elop beyond 14 days or the appearance of the primitive streak.

264 ectively, inhibit or induce formation of the primitive streak.

265 senchymal transition and ingress through the primitive streak.

266 lecules BMP4 and Vg1/GDF1 in positioning the primitive streak.

267 ls into mesodermal subtypes that reflect mid-primitive-streak cardiogenic mesoderm and posterior-prim

268 orcine PGCs originate from the posterior pre-primitive-streak competent epiblast by sequential upregu

269 ve-streak cardiogenic mesoderm and posterior-primitive-streak hemogenic mesoderm.

270 e and BM, Meflin is more highly expressed in primitive stromal cells that express platelet-derived gr

271 Also in contention is whether these primitives take the form of time-invariant muscle coacti

272 imulation of Tnfalpha production in trout, a primitive teleost fish.

273 recometary materials that will later fall on primitive telluric planets, bringing a wealth of complex

274 ld World monkeys-and are thus viewed as more primitive than the stem ape Proconsul.

275 The dentition of Purgatorius is more primitive than those of all known living and fossil prim

276 ostcanine dental formula that resembles more primitive tinodontid symmetrodonts on the one hand, and

277 Our characterization of this primitive TLR and identification of a bacterial pathogen

278 tation of the object) allows the appropriate primitives to be engaged.

279 Evidence suggests that the CNS uses motor primitives to simplify movement control, but whether it

280 daptation is implemented by cosine tuning of primitives to the current direction of the error, which

281 The contribution of the primitives to the motor output is determined by both top

282 This specimen combines primitive traits seen in early Australopithecus with der

283 s of human gene regulatory networks activate primitive transcriptional programs, driving common hallm

284 Additionally, MR766 is highly trophic toward primitive trophoblast, which may put the early conceptus

285 (Hg1201), which features one CuO2 plane per primitive unit cell.

286 comprise a 12-atom and 18-atom rhombohedral primitive unit cells in the symmetry, which are characte

287 ns contributed locally adaptive variation to primitive varieties.

288 Angiogenesis produces primitive vascular networks that need pruning to yield h

289 show in mouse that endocardial cells form a primitive vascular plexus surrounding the liver bud and

290 matrices formed organoids that consisted of primitive vascular structures surrounding a polarized ep

291 In this article, we hypothesize that a primitive version of C3 comprised the first element of t

292 In this way, they act as primitive versions of today's protein catalysts, elongat

293 vise a probe for tunnelling, a computational primitive where classical paths are trapped in a false m

294 express internal states displaying "emotion primitives," which are general characteristics common to

295 Additionally, we sequenced 100 accessions of primitive, wild and cultivated citrus.

296 The reconstructed mandible is remarkably primitive, with a long and narrow dental arcade more sim

297 he, and lateral hypothalamus, which regulate primitive, yet fundamental functions, such as circadian

298 inst pathogenic microbes, our body employs a primitive, yet highly sophisticated and potent innate im

299 on sampling biases reflect the expression of primitive, yet potentially ecologically adaptive, behavi

300 otif) receptor 2(+) macrophages derived from primitive yolk sac, recombination activating gene 1(+) l