ライフサイエンスコーパス: primordium

1 ype II lineages DM1-4, form the posterior EB primordium.

2 ed for the initial formation of the thalamic primordium.

3 patterned mature structure from an embryonic primordium.

4 line identity are present caudal to the main primordium.

5 ion of thymic epithelial cells in the thymus primordium.

6 sequent migration of PGCs through the midgut primordium.

7 ivision and the initiation of a lateral root primordium.

8 lop from archesporial cells in the L2 of the primordium.

9 l crest cells that migrate to the pancreatic primordium.

10 tivation domain in the leading region of the primordium.

11 of secreted factors adjacent to the sensory primordium.

12 nt membrane dissolution in the primary mouth primordium.

13 nd lower (abaxial) domains in the developing primordium.

14 overall cellularity or volume of each shared primordium.

15 ed into the condensed cartilage of the digit primordium.

16 y the migrating posterior lateral line (pLL) primordium.

17 espite the early expression of Snail in that primordium.

18 regulators that are expressed in the spleen primordium.

19 wer (abaxial) domains in the developing leaf primordium.

20 (TCF7L2), in the induction of the pituitary primordium.

21 lls are incorporated into the incipient leaf primordium.

22 1(+) somatic progenitor pools in the gonadal primordium.

23 bryogenesis and become attached to the brain primordium.

24 unbranched fibers in the center of the brain primordium.

25 nhibitors, Kip1 and Ink4c, in the cerebellar primordium.

26 ed at embryonic day 16 (E16) in the striatal primordium.

27 atterns of bmp4 expression in the mandibular primordium.

28 l axis of the wing-like bilateral cerebellar primordium.

29 nd then lost during expansion of the hepatic primordium.

30 sion, rather than fusion, of the thin medial primordium.

31 ls and reduced vasculogenesis of the splenic primordium.

32 ate patterns of cell division in the growing primordium.

33 dorsal and ventral domains of the forebrain primordium.

34 s a central role in positioning of the organ primordium.

35 el provascular strands within the initiating primordium.

36 he size and shape of a zebrafish sense organ primordium.

37 ) required for kni expression in the L2 vein primordium.

38 some taxa limbs and genitals share a common primordium.

39 xcr7b expression to the trailing zone of the primordium.

40 y distributions of myosin and Bazooka in the primordium.

41 (ZLI) at the rostral border of the thalamic primordium.

42 oves forward and merges with the anterior EB primordium.

43 a linear Sdf1-signaling gradient across the primordium.

44 repressing a root-specific gene lateral root primordium 1 (LRP1) via histone deacetylation.

45 tion of the zebrafish posterior lateral line primordium, a cohort of about 200 cells that migrates ov

46 In the developing leaf primordium, a line is drawn across a field of seemingly

47 e-recombinase line that acts in the cortical primordium after its specification is complete, permitti

48 of the adrenal cortex from the adrenogonadal primordium (AGP) have yet to be determined.

49 e migrating and coalescing into the ganglion primordium, all cells were cycling, cell cycle length wa

50 lium of the distal and the proximal mandible primordium already occupy different spatial locations in

51 that the somatopleure acting as the amniotic primordium also serves as a source of embryonic cells, w

52 Zic2a and Zic2b in patterning the forebrain primordium, an important signaling source during craniof

53 ion leads to dramatic disorganization of the primordium and a loss of proto-NM formation.

54 s associated with subdivision of the incisor primordium and a multiplication of its stem cell-contain

55 ion is driven by periodic lengthening of the primordium and a stable Wnt/beta-catenin activation doma

56 ls (presumptive progenitors) move out of the primordium and are incorporated into NMs; this results i

57 s are broadly distributed throughout the gut primordium and are not derived from a localized and exog

58 fic medial-lateral domains of the cerebellar primordium and derived a positional fate map of the muri

59 somite-derived cells migrate into the tongue primordium and give rise to muscle cells in the tongue.

60 gnaling is active in the leading zone of the primordium and global Wnt inactivation leads to dramatic

61 epithelial cells emerges in the early tooth primordium and identify these cells as a signaling cente

62 first cortical cell divisions of the nodule primordium and in growing nodules.

63 ay be involved in patterning the early optic primordium and in promoting the differentiation of retin

64 xb8a is expressed in the leading part of the primordium and is required for the correct speed and ext

65 f Nf2, NPCs of the cortical hem, hippocampal primordium and neocortical primordium overexpand, while

66 ynamic changes in the zebrafish lateral line primordium and observed interactions between myosin IIA

67 us arrest of cell proliferation in the organ primordium and possibly reduces the rate of cell divisio

68 igration, such as the zebrafish lateral line primordium and primordial germ cells, Drosophila border

69 the early steps of patterning of the neural primordium and proliferation of neural progenitors.

70 s auxin signaling in the incipient gynoecial primordium and strengthen the concept that cytokinin reg

71 undantly for morphogenesis of the cerebellar primordium and subsequent cerebellar differentiation, bu

72 Development of the nodule primordium and subsequent nodule maturation was signific

73 interwoven meshwork of the fetal myocardial primordium and subsequent persistence of deep trabecular

74 This close association between the mouth primordium and the anterior neural tube in both ascidian

75 ssential for the expansion of the pancreatic primordium and the development of endocrine islets.

76 but is dispensable for the migration of the primordium and the initial development of neuromasts.

77 after the independent formation of the mouth primordium and the neural tube.

78 in severe reductions in the size of the eye primordium and the transformation of the eye field into

79 vn is not expressed in the embryonic wing primordium and thus has to be induced de novo in the nas

80 bules of Drosophila develop from the hindgut primordium and visceral mesoderm.

81 gradient across the entire A/P extent of the primordium, and acts directly at a distance from its sou

82 ccumulate in the shoot apical meristem, leaf primordium, and emerging petiole.

83 mig-38 is expressed in the gonad primordium, and expression continues throughout DTC migr

84 on and skeletogenesis only the ventral brain primordium, and not the prechordal plate, is an importan

85 due to ectopic apoptosis in the dorsal wing primordium, and we could rescue wing development in the

86 ossible mechanisms to polarize the incipient primordium are discussed, including meristem-derived sig

87 ally distinct organs from a common olfactory primordium are unknown.

88 We show that the siphon primordium arises within a non-dividing field of lateral

89 ition such that they fuse with the migrating primordium as it advances, and later contribute to the l

90 sociate tightly with the invaginating midgut primordium as it enters the embryo; however, in embryos

91 a progenitor pool at the leading zone of the primordium as neuromasts are deposited from the trailing

92 tial formation of the posterior lateral line primordium, as well as during organ patterning, migratio

93 The Drosophila Dorsal Air Sac Primordium (ASP) is a tracheal tube that grows toward Br

94 n grows from an epithelial tube (the air sac primordium (ASP)) that arises during the third larval in

95 and transported by cytonemes to the air sac primordium (ASP).

96 cytonemes in order to signal to the air sac primordium (ASP).

97 o and reside in the epithelium of the tongue primordium at an early embryonic stage, acquire epitheli

98 onnecting the neural tube lumen to the mouth primordium at larval stages.

99 gynoecium requires that the early gynoecial primordium be partitioned into distinct spatial domains

100 The eye primordium begins with a default ventral fate, on which

101 latent precursors that are deposited by the primordium between primary neuromasts.

102 hat controls cell proliferation at the petal primordium boundaries.

103 mation of the midvein, and appearance of the primordium bulge.

104 Barx1 is absent from the spleen primordium but highly expressed in the mesogastrium, ind

105 rface area expansion throughout the cortical primordium but no gyrification.

106 activated in a broad domain across the head primordium, but later retract so that their expression i

107 ated in the thymic fated domain of the early primordium by embryonic day 11.5 and is expressed in a F

108 s that predecessor cells invade the cortical primordium by tangential migration from the subpallium.

109 enes expressed in the Drosophila CNS midline primordium cells, and show that while the expression pat

110 ubular eggshell appendages is derived from a primordium comprising two distinct cell types.

111 (2) The C-shaped primordium contains a characteristic balloon-like capill

112 The cerebellar primordium contains two germinative zones, the rhombic l

113 In zebrafish embryos, a migrating primordium deposits seven to nine clusters of sensory ha

114 ajority of cells in an emerging lateral root primordium derive from the central file of pericycle fou

115 system, epithelial cells within a cyst-like primordium develop diverse shapes through largely unknow

116 patio-temporal sequence of events leading to primordium development has not been established.

117 mber of genes that affect various aspects of primordium development including positioning, growth, an

118 zed the cell behavior associated with flower primordium development starting from a stage at which th

119 icum infection process, initiation of nodule primordium development, and subsequent nodule organogene

120 company, and may direct, different stages of primordium development.

121 he earliest steps leading up to lateral root primordium development.

122 he parathyroid-specific domain in the common primordium did not express Pth and could not maintain th

123 xus region, which we termed Di-Mesencephalic primordium (DiMes).

124 proliferating progenitor cells and eventual primordium disorganization.

125 In aly/aly mice, the LN primordium dissipates irreversibly late in gestation; in

126 Wnt pathway coreceptor expressed in the eye primordium, does not prevent expression of lens inductio

127 t within Wnt1(+) territory, a climbing fiber primordium dominated by Ngn1-expressing cells.

128 t arise in the rhombic lip of the cerebellar primordium during embryogenesis.

129 Foxa2 (formerly HNF-3beta) in the pancreatic primordium during midgestation.

130 We show that laser ablation of atrial primordium ectoderm also results in a failure to form gi

131 ired JAG and were genetically separable from primordium emergence.

132 ing gradient is initiated at the rear of the primordium, equilibrates across the primordium within 20

133 The cells of the claustrum primordium express Nr4a2; they are formed in combination

134 us, Single-minded directly regulates midline primordium-expressed genes, but in some cases plays a pr

135 trol expression of most, if not all, midline primordium-expressed genes, the role of Notch in directl

136 In contrast, midline primordium expression of other genes shows a strong depe

137 Midline primordium expression of the rhomboid gene is dependent

138 t that Wg controls the expansion of the wing primordium following D-V segregation by fueling this aut

139 e that Wg promotes the expansion of the wing primordium following the D-V segregation by fueling this

140 ly, Lmx1a and Gdf7 expression identifies the primordium for hindbrain choroid plexus epithelial cells

141 ession patterns in the first branchial arch (primordium for jaw) and mutant phenotypes; inactivation

142 Germinal matrix (GM), a key primordium for the brain reward circuitry, is unique amo

143 candidate enhancers from the maxillary arch (primordium for the upper jaw) of mouse embryos.

144 hizobia but had significantly reduced nodule primordium formation, suggesting that auxin hypersensiti

145 These indicate that, after lung primordium formation, Wnt signaling is not essential for

146 mbryonic mandibular condylar growth and disc primordium formation.

147 m-adjacent pericycle, but did not rescue the primordium formation.

148 ells found in dgt1-1 roots were unrelated to primordium formation.

149 e Diageotropica (Dgt) gene in tomato prevent primordium formation.

150 nd LHK3 to mediate cell divisions for nodule primordium formation.

151 nd captured time-lapse movies as the gonadal primordium formed.

152 are established and maintained when the lung primordium forms and starts to branch.

153 cts reprogramming from transit amplifying to primordium founder cell fate in Arabidopsis inflorescenc

154 FGF8 diffuses through the mouse neocortical primordium from a discrete source in the anterior telenc

155 enables the coalescence of the lateral line primordium from an initial fuzzy pattern into a compact

156 tc-independent function protects the retinal primordium from Hh activity, defines the stalk/retina bo

157 led by RA that lead to formation of the lung primordium from the primitive foregut remain unclear.

158 least in the apical portion of the gynoecial primordium, from obtaining medial fates.

159 monstrate that shade-induced changes in leaf primordium gene expression largely do not overlap with t

160 The rear of the primordium generates this gradient through continuous se

161 lopment: whether the axillary bud, or branch primordium, grows out to give a lateral shoot or remains

162 ions at the interface between patterning and primordium growth in Arabidopsis flowers.

163 (RA) is essential for formation of the lung primordium; however, little is known about the impact of

164 th a role in the transition from meristem to primordium identity, JAG directly repressed the meristem

165 The somatopleure is the amniotic primordium in amniote development, but its boundary to t

166 ich instructs the formation of the adult eye primordium in Drosophila.

167 Analysis of the 3rd pouch-derived primordium in Gcm2-/- mutants showed the parathyroid-spe

168 leaves, suggesting that the terminal leaflet primordium in M. truncatula has a unique developmental m

169 e protrusions prior to fusion of a key organ primordium in mammalian development.

170 n surrounding cells to join the growing wing primordium in response to Wg.

171 are formed in the deep part of the claustrum primordium in the lateral pallium, but they migrate vent

172 hyroid glands arise from a shared endodermal primordium in the third pharyngeal pouch (3rd pp).

173 ntiated axon tracts of these lineages form a primordium in which all of the compartments of the centr

174 three regulatory cells of the somatic gonad primordium in young larvae.

175 The posterior lateral line primordium in zebrafish provides an amenable model to st

176 expressed in the genital ridge (the gonadal primordium) in both sexes and then becomes testis-specif

177 essed in the neural crest-derived hyoid bone primordium, in addition to mesoderm-derived osteochondra

178 quent impaired growth of the caudal cortical primordium, including the hippocampus.

179 negative receptor in the central neocortical primordium induced cells to adopt a more posterior area

180 nt larvae (Lgl) tumor suppressor in the wing primordium induced epithelial neoplasia in its Homothora

181 tween rhizobia and their host plants, nodule primordium induction and infection occur.

182 witch is ideally suited for iterative flower primordium initiation and orchestrates additional auxin-

183 flow during the earliest stages of gynoecial primordium initiation and outgrowth.

184 us reveals a mechanistic link between flower primordium initiation and subsequent steps in flower mor

185 al root formation by inhibiting lateral root primordium initiation.

186 NA for induction of key regulators of flower primordium initiation.

187 MP that furthermore jointly regulate flower primordium initiation.

188 gans somatic gonad develops from a four-cell primordium into a mature organ that differs dramatically

189 iven mechanisms to convert a two-dimensional primordium into a three-dimensional structure, and provi

190 t the transformation of this two-dimensional primordium into a tube involves out-of-plane bending fol

191 al development, patterning events divide the primordium into distinct domains that will give rise to

192 act as a binary switch to subdivide the wing primordium into PE and DP, and assign crucial roles for

193 generation of boundaries to divide an organ primordium into smaller fields.

194 at Math1 cells migrate out of the cerebellar primordium into the rostral hindbrain to populate specif

195 The initial steps of atrial primordium invagination are similar to otic placode inva

196 Drosophila mesoderm layer from an epithelial primordium involves a transition to a mesenchymal state

197 The periodic lengthening of the primordium is controlled by Wnt/beta-catenin/Fgf-depende

198 The Drosophila wing primordium is defined by expression of the selector gene

199 Initially, the cerebellar primordium is divided into five cardinal lobes, which ar

200 ng insects while the Drosophila compound eye primordium is evolutionarily related to the yet little s

201 onset of migration, the compact state of the primordium is not fully established, as isolated cells w

202 in-rich CR cells that covers the neocortical primordium is not required to direct layer order.

203 ate Xenopus, we find that although the mouth primordium is not topologically continuous with the neur

204 The pLL primordium is organized into polarized rosettes represen

205 uent maintenance and growth of the adult eye primordium is regulated partly by redundant and partly b

206 mation of a lateral root from a lateral root primordium is repressed as water availability is reduced

207 we propose that Hh signaling from the brain primordium is required for proper specification of the s

208 PDX1+ ventral pancreas and a SOX17+ biliary primordium is Sox17-dependent.

209 l (D) and ventral (V) compartments, the wing primordium is specified by activity of the selector gene

210 Early in development, the wing primordium is subdivided into a thin layer of peripodial

211 auxin application to a single side of a leaf primordium is sufficient to recapitulate the asymmetries

212 m indeterminate meristem to determinate leaf primordium is the down-regulation of KNOX1 genes ortholo

213 localizes adjacent to the developing gonadal primordium, is required to prevent the SGPs from over-ex

214 zebrafish met is expressed in the cerebellar primordium, later localizing to the ventricular zone (VZ

215 his study, we use the zebrafish lateral line primordium (LLP), a group of migrating epithelial cells

216 ete sensory patches during evolution of this primordium may be related to subdivision of an early pan

217 ractions between these two pathways regulate primordium migration and prosensory organ formation.

218 or rosette formation, atoh1a expression, and primordium migration.

219 signaling, however the rescue of cerebellar primordium morphogenesis is independent of both Gbx and

220 , with msbA2 mutant cells stimulating nodule primordium morphogenesis, but failing to invade plant ti

221 fan-shaped body primordium, the posterior EB primordium moves forward and merges with the anterior EB

222 uting, and the migration of the lateral line primordium, neural crest cells, or head mesendoderm.

223 rom a rostromedial source in the neocortical primordium (NP), forms a rostral-to-caudal (R/C) gradien

224 te the left and right sides of an initiating primordium occupying niches that differ in their distanc

225 nalysis of gene expression in the cerebellar primordium of E11.5 Neurog1 null (Neurog1-/-) mice to id

226 (1) The glomerular primordium of medaka - unlike the one of zebrafish - exh

227 le studied stem cell based postembryonic eye primordium of primitive insects.

228 the cell proliferation defect in the frontal primordium of Tgfbr2 mutant.

229 The primordium of the Arabidopsis (Arabidopsis thaliana) gyn

230 Null mutant embryos appear to lack the primordium of the atrioventricular node.

231 cells include the first neurons seen in the primordium of the cerebral cortex, before the onset of l

232 The primordium of the EB has a complex composition.

233 dence of autocrine Hh signaling in the optic primordium of the embryo.

234 the head to form the otic vesicle (OV), the primordium of the inner ear and CVG.

235 In higher vertebrates, the primordium of the nervous system, the neural tube, is sh

236 ression is restricted to Rathke's pouch, the primordium of the pituitary gland.

237 The optic vesicle is a multipotential primordium of the retina, which becomes subdivided into

238 plex developmental program that connects the primordium of the upper urinary tract [the nephric duct

239 em is afforded by the migrating lateral line primordium of the zebrafish.

240 A leaf undergoes determinate growth from a primordium on flank of the shoot apical meristem.

241 Low levels of reelin in the cortical primordium, or diffusion of reelin from other sites, may

242 at Lef1 function is not required for initial primordium organization or migration, but is necessary f

243 broblast growth factor (FGF) source controls primordium organization, which, in turn, regulates the p

244 t in the anterior foregut where the tracheal primordium originates and targeted ablation of Bmp4 (Bmp

245 vatives, including the palps and oral siphon primordium (OSP).

246 hem, hippocampal primordium and neocortical primordium overexpand, while production of Cajal-Retzius

247 Surprisingly, the overall primordium patterning, as assayed by the expression of v

248 The posterior lateral line primordium periodically deposits prosensory organs as it

249 catenin signaling in the leading zone of the primordium plays a crucial role in orchestrating lateral

250 Here, we study the posterior lateral line primordium (PLLP) a group of about 100 cells, destined t

251 ells in the zebrafish posterior lateral line primordium (PLLp) along a path defined by Cxcl12a expres

252 Migration of the posterior lateral line primordium (pLLP) generates the zebrafish sensory organs

253 The posterior lateral line primordium (PLLp) migrates caudally and periodically dep

254 The posterior lateral line primordium (pLLp) migrates caudally, depositing neuromas

255 Wnt signaling in the posterior lateral line primordium (pLLP), a cohort of ~100 cells that collectiv

256 tion in the zebrafish posterior lateral line primordium (pLLp), a group of approximately 100 cells th

257 Wnt/beta-catenin and Fgf signaling maintain primordium polarity by differential regulation of gene e

258 l cortex and gonad are derived from the same primordium present during early urogenital development.

259 In the developing cortical primordium, RACK1 protein is expressed in a high-rostrom

260 n canal that conducts rhizobia to the nodule primordium requires a functional Rab GTPase located in G

261 Furthermore, the CNC-derived frontal primordium requires TGFbeta IIR to undergo terminal diff

262 ssed in the leading and trailing part of the primordium, respectively.

263 Likewise, neoplasia in the eye primordium resulted in loss of Elav, a retinal cell mark

264 rdia also increases the size of the antennal primordium resulting in the induction of ectopic antenna

265 on of both Foxa1 and Foxa2 in the pancreatic primordium results in complete loss of Pdx1 expression a

266 al root emergence but, intriguingly, not for primordium specification itself.

267 he 'Dlx codes' appear to regionalize the jaw primordium such that Dlx1/2 regulate upper jaw developme

268 tor of this process in the mouse hippocampal primordium, such that Lhx2 overexpression promotes neuro

269 e was found expressed in the vascular vessel primordium, suggesting KANK genes are a component of the

270 myogenic progenitors migrate into the tongue primordium, suggesting that CNC cells play an instructiv

271 onad are thought to be derived from a common primordium that divides into separate tissues during emb

272 in zebrafish, which is formed by a cohesive primordium that migrates from head to tail and deposits

273 After sex is determined in the gonadal primordium the global sex determination pathway is dispe

274 ed from its initial creation by an embryonic primordium, the blastema that emerges at the injury site

275 t as an integral part of the fan-shaped body primordium, the posterior EB primordium moves forward an

276 texts, such as in the zebrafish lateral line primordium, the vertebrate pancreas, the Drosophila epit

277 he development of the tunicate atrial siphon primordium, thought to share homology with the vertebrat

278 ormed from a thicker and shorter postmitotic primordium through unidirectional extension, characteris

279 e prominently expressed in the early cardiac primordium throughout the animal kingdom.

280 other sources did not invade the neocortical primordium to compensate for hem loss.

281 e the expression of Sf1 in the adrenogonadal primordium to ensure adrenal development.

282 sink in the migrating zebrafish lateral line primordium to generate SDF1 gradients.

283 It is first required for the mesoderm primordium to lose its epithelial polarity.

284 or 8 (FGF8) was misexpressed in the cortical primordium to rearrange the area map.

285 Thus, DNA methylation primes the prostate primordium to respond to developmental cues mediating ou

286 Cells throughout the Drosophila wing primordium typically show subcellular localization of th

287 tedly caudal and noncontiguous to cerebellar primordium; ventral CN subdivisions arise from more rost

288 maize PIN1 expression at the incipient leaf primordium was greatly reduced in abph1 mutants.

289 The earliest claustral primordium was identified superficially, dorsal to the o

290 ent of the mechanically induced lateral root primordium was independent of an auxin supply from the s

291 events that lead to formation of the gonadal primordium, we generated transgenic strains to label the

292 NC)-derived ectomesenchyme in the mandibular primordium where intramembranous ossification takes plac

293 The simple Caenorhabditis elegans gonadal primordium, which contains two somatic gonad precursors

294 es: Fgf signalling attracts them towards the primordium, which counteracts Sdf1alpha/Cxcr4b-mediated

295 ion factor (TF) gradients in the neocortical primordium, which define a "protomap" in the embryonic v

296 The NMs are deposited by a migrating pLL primordium, which is organized into polarized rosettes (

297 DALv2 neurons form the anterior EB primordium, which starts out as a bilateral structure, t

298 are deposited from the trailing part of the primordium, while progenitor cells in the leading part g

299 r of the primordium, equilibrates across the primordium within 200 min, and operates near steady stat

300 morphogenesis to give rise to the cerebellar primordium within which the various cerebellar neuron ty