ライフサイエンスコーパス: principle

1 translocation time and verify the detection principle.

2 ata analyses followed the intention-to-treat principle.

3 abrication of active particles based on this principle.

4 ns-influence might be a more general f-block principle.

5 erformed according to the intention-to-treat principle.

6 w) with net exchange calculated via the Fick principle.

7 ne in accordance with the intention-to-treat principle.

8 g/mL (R(2) = 0.9339) by the turn off-turn on principle.

9 ement this process is the temporal coherence principle.

10 ites based on the minimum description length principle.

11 ins of life from chemical and physical first principles.

12 design fast ion conductors following simple principles.

13 , single-layer Tl2O, is discussed from first principles.

14 simple model derived essentially from first principles.

15 provides additional support for biophysical principles.

16 rocess, we elucidate several key mechanistic principles.

17 ved barriers to the pursuit of best practice principles.

18 to natural stimuli and find three organizing principles.

19 ationic attributes might be based on similar principles.

20 00 and 6,000 muatm exposures, and a proof-of-principle 30,000 muatm exposure.

21 Like traditional voting, the principle accepts unique problems, such as panel decisio

22 lor active particles; (2) attempts to design principles according to which active particles interact

23 Such driving in principle allows one to realize arbitrarily fast anneali

24 Such a unique working principle allows the system to overcome challenges faced

25 hesized at the air/water interface as it, in principle, allows estimation of the crystallinity by per

26 Importantly, control principles also allow us to investigate the involvement

27 tention because of its intriguing scientific principle and potential application.

28 able differ intrinsically in their detection principle and thus might exhibit limitations for a speci

29 that solves this combinatorial problem in a principled and practical way.

30 Altogether, our study reveals the basic principles and a circuit diagram enabling speed modulati

31 scribe matter-photon interactions from first principles and addresses the emergence of new states of

32 fects models according to intention-to-treat principles and adjusted for centre and baseline weight.

33 We review key principles and evolving concepts in the care of MPM pati

34 This review introduces readers to the basic principles and fundamentals of flow chemistry and critic

35 It is based on domain adaptation principles and is a generalization of previous work that

36 ments with individual NTs coupled with first-principles and molecular dynamics calculations demonstra

37 Advances in bioinspired design principles and nanomaterials have led to tremendous prog

38 uld be governed by the highest science-based principles and policies.

39 g with prognostic imbalance and to the basic principles and relative trustworthiness of various adjus

40 tic biology literature that illustrate these principles and speculate on their implications for furth

41 Very little is known about the principles and the molecular mechanisms governing this t

42 er nanomedicines: (i) physicochemical design principles, and (ii) clinical trial design, which are fr

43 n bundle" to help adherence to best practice principles, and 3) a "performance bundle" to identify an

44 ues are formed by normal learning and memory principles, and the understanding of the brain mechanism

45 This technology is, in principle, applicable to any endogenous gene, allowing d

46 is by nanoLC-MS(2), and demonstrate proof-of-principle applications of the duplex and triplex tags fo

47 d on the elastic-viscoelastic correspondence principle applied to Hertzian contact mechanics to model

48 rimary visual cortex (V1), its computational principles apply with equal validity to any cortical str

49 d metareasoning framework may thus provide a principled approach to examining emotions.

50 In this study, a first-principles approach is presented that combines accurate

51 D-SELEX, represents a simple and rapid first principles approach to determining the binding and cleav

52 miRNA targeting principles are consistent with observations in other spe

53 g and quantum communication - basis-specific principles are invoked that are altogether distinct from

54 As both the graphene and device principles are transferrable to arbitrary semiconductor

55 ispersion and intrinsic lifetimes from first-principles as input.

56 lar water splitting applications using first-principles-based approaches, and highlights the key role

57 The principles behind the theoretical, experimental, and ana

58 ISG15 via SARS-CoV PLpro in complex with the principle binding domain of human ISG15 (hISG15) and mou

59 re fabricated using self-assembled monolayer principle by modifying Au electrode with cysteamine (Cys

60 erent instantiations of the same algorithmic principles by showing that existing results from the lea

61 ol 1,4,5-trisphosphate receptor (ITPR2), the principle calcium release channel in hepatocytes.

62 ron diffraction analysis combined with first-principles calculation allows us to determine that zone

63 In agreement with experiments, first-principles calculation confirms the good stability and i

64 erties of ternary FeSexTe1-x, based on first principle calculations.

65 First-principles calculations indicate that RSFs with differen

66 In addition, first-principles calculations indicate that this phase transit

67 Cu-substituted Co3 O4 supplemented by first-principles calculations is reported to reveal the mechan

68 First-principles calculations reveal a strong coupling between

69 photoelectrochemical measurements and first-principles calculations to approve the higher tendency o

70 Here, based on first-principles calculations, anisotropic Eliashberg theory,

71 To improve the predictive power of first-principles calculations, there is a pressing need to use

72 Based on first-principles calculations, we reveal explicitly the spin c

73 ed by electrochemical measurements and first-principles calculations.

74 structure, in full accordance with our first-principles calculations.

75 sion electron microscopy analysis, and first-principles calculations.

76 a1/hcp-Mg orientation relationship via first principles calculations.

77 xpect that our established relationships and principles can help guide future optimization of functio

78 Further principle component analyses(PCA) of RRS simulations agr

79 At the phylum level, Principle Component Analysis revealed significant segreg

80 e-frequency domain features and then applies principle component analysis to reduce the dimension of

81 major clinical variables was captured on two principle components (PCs).

82 ilibrium between multiple conformers that in principle could recognize different binding partners.

83 First principle density functional calculations show that even

84 ion of the CuO chains, as confirmed by first-principles density functional theory (DFT) simulations.

85 First-principles density functional theory calculations on the

86 nd Ni layers, which is corroborated by first-principles density functional theory calculations.

87 etal transition using a combination of first-principles density-functional and many-body calculations

88 As a proof-of-principle, deoxynivalenol (DON), an important mycotoxin,

89 Moreover, the principles described here may serve as a model for cultu

90 ediatrician with a good understanding of the principles described in this article.

91 relative to other components and can be, in principle, discerned with improved sensitivity in the ph

92 In principle, either tier could translocate ahead of the ot

93 c) of plutonium is predicted utilizing first-principles electronic structure coupled with a self-cons

94 from point [Formula: see text] This locality principle elucidates the transferability of functional g

95 hemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and

96 These data provide proof-of-principle evidence for the therapeutic potential of PSC-

97 by taking advantage of the structural design principles evolved by nature.

98 In a proof-of-principle experiment, treatment of these two subtypes wi

99 rate the efficacy of our methods in proof of principle experiments and application to real world prob

100 Here, we present proof of principle experiments of an optical gating concept for f

101 ngineered gene drives due to recent proof of principle experiments with the CRISPR-Cas9 system as a d

102 In proof-of-principle experiments, we manipulated apterous, a regula

103 In this article, we establish a proof-of-principle for methods to initiate and then monitor such

104 nstruct the biliary tree, providing proof of principle for organ regeneration using human primary cho

105 of this concept is reviewed here and a novel principle for the design of oxygen electrocatalysts is p

106 precipitation of second phase is the guiding principle for the development of a host of high strength

107 gainst intracellular Mtb, providing proof of principle for the efficacy of a "release and kill" strat

108 Proof of principle for the potential of scanning LC-FAIMS-MS in o

109 uation, keeping this ratio constant is a key principle for the power scaling of laser-induced filamen

110 These data provide proof-of-principle for the view that newly generated ASCs can acq

111 ent for type 1 diabetes and provide proof of principle for therapeutic cloning combined with cell the

112 Proof of principle for this therapeutic approach was demonstrated

113 While guidance on statistical principles for clinical trials exists, there is an absen

114 We review important guiding principles for method development, discuss the state of

115 We also discuss guiding principles for more effective use of eDNA methods, highl

116 rovide possibilities in advancing the design principles for photo-rechargeable lithium ion batteries.

117 molecular dynamics study for deciphering the principles for specific stop codon recognition by RFs id

118 d the Council of Medical Specialty Societies principles for the development of clinical guidelines as

119 onic polarization transfer and provide vital principles for the rational design of long-coherence ele

120 d the formulation of the general engineering principles for the selection of polymeric materials for

121 Here we introduce a principled framework to estimate annotation-stratified g

122 We highlight some principles from evolutionary theoretical models that can

123 Using principles from statistical physics and information theo

124 However, it remains unclear whether this principle generalizes to species with a columnar organiz

125 t it is not known whether the organisational principles governing continuous maps may extend to the i

126 However, the principles governing interareal functional connectivity

127 rily driven differences in the computational principles governing specialized circuits versus more ge

128 phase diagram of the Ti2AlC-Cr2AlC via first-principles-guided Bayesian CALPHAD framework that accoun

129 The moral principle guiding intersubject trade-off decision making

130 While the general principles guiding the nonclinical and clinical developm

131 We show that the reduction principle holds for all of these cases by developing a u

132 Here, we define the engineering principles impacting biological activity, detail a synth

133 G-quadruplex structure-switching biosensing principle in graphene nanoelectronics.

134 inhibition as a disease-modifying treatment principle in PD.

135 We examined this principle in the association areas, PFC, and ventral int

136 ABSTRACT: An important principle in the organization of the somatosensory corte

137 esigned sequence is crucial to verify design principles in genome synthesis.

138 Underlying principles in measuring pollen exposure and associated m

139 This is essential for studying the basic principles in order to develop a full understanding abou

140 practical clinical paradigms to apply these principles in stroke and realise the promise of precisio

141 that the synergistic application of two such principles in the design of peptoid foldamers yields a n

142 These principles include positive feedback loops that are requ

143 were done according to an intention-to-treat principle, including data from all patients randomly ass

144 ients with mild symptoms, general management principles, including making a confident diagnosis and o

145 foundation for expansion of the theranostic principle into other oncology indications.

146 These results highlight new principles involved in the fundamental process of habitu

147 A core principle involves a comprehensive assessment and integr

148 The assay principle is based on the selective recognition from apt

149 A general principle is concluded that the eg occupancy of the acti

150 This general principle is demonstrated by a change in thermal stabili

151 A sound scientific principle is that the body is constantly sensing and res

152 Its principle is to use measurement of risk factors to creat

153 talyst based on metal-semiconductor junction principles is presented.

154 of different phenomena that violate a basic principle, Kasha's rule, when applied to photochemical r

155 traction enhanced the recovery of the active principles, limiting extraction time and solvent waste.

156 d behaviors through the functional output of principle medium spiny neurons (MSNs), whereas dysfuncti

157 The first-principles model better quantifies interindividual diffe

158 ss and altered arousal and further establish principled neurophysiological markers of these states.

159 n, using a novel strategy that relies on the principle of 'energetic frustration'.

160 Despite the key principle of ABCE model in whorl specification, the unde

161 s is well understood and rationalized by the principle of an "energy funnel", the carotenoids still p

162 With MRET, we demonstrate the principle of an MRI-based ruler for nanometre-scale dist

163 We propose that, conceptually, the principle of cognition could amount to the existence of

164 precision medicine over the past decade, the principle of companion diagnostics has gained increasing

165 hin a broad range of peak powers against the principle of constant P/Pcr.

166 Specificity is a core principle of exercise training to promote the desired ad

167 Thus, we hypothesize that the coding principle of facial features in the middle patch of face

168 birds and mammals strongly suggests that the principle of honest signalling via vocal tract resonance

169 Proof of principle of in vivo targeting of human islets by [(11)C

170 ors of secondary injury has been the guiding principle of modern TBI management.

171 The design principle of NDP-V is to reduce the conformational disor

172 A core principle of nervous system organization is the diversif

173 emonstrate that this notion is not a general principle of neuronal development by documenting the tim

174 The principle of nutrient-dependent fitness costs has implic

175 g to pre-generated sequences produced on the principle of randomly permuted blocks with variable bloc

176 A general principle of sensory processing is that neurons adapt to

177 d signals, however, is possible by using the principle of stochastic resonance, where noise is added

178 d makes it possible to observe a reciprocity principle of the RDNMR response.

179 the DMN appears to be organized according to principles of a segregated highway - suggesting it is op

180 Understanding the general principles of binding site interplay will pave the way f

181 Specifically, we highlight five fundamental principles of brain network development during the criti

182 e a model for language dynamics based on the principles of cellular automata/agent-based modeling and

183 and mechanisms for SM can reveal fundamental principles of computations in sensory cortices, from mou

184 Altogether, our study reveals novel principles of concerted transcriptional regulation by mu

185 perties have been developed using the design principles of crystal engineering and structure-property

186 anying poster, we provide an overview of how principles of developmental biology have been essential

187 3C from EBV-recombinants, revealed important principles of EBNA3 binding to chromatin.

188 Yet, they often conflict with elementary principles of economic theory and are often described as

189 Recently, major principles of function for light-gated ion channels have

190 tors (TFs) is critical for understanding the principles of gene regulation.

191 Although the fundamental principles of innate control of adaptive immunity are we

192 ur studies bring new insights to the general principles of ligand-receptor interactions.

193 Here, we review six principles of living systems and how they compare and co

194 As the basic physicochemical principles of matrix crosslinking and osmotic swelling a

195 toward future directions in studying how the principles of mechanics and chemistry combine to drive m

196 ture can be achieved by mimicking the design principles of natural photosynthetic proteins.

197 ly different species are needed to infer the principles of organogenesis.

198 uted from the flow field, accounting for the principles of physics (ie, the Navier-Stokes equations).

199 ies are important in testing the fundamental principles of physics but producing antihydrogen in larg

200 Application of the principles of population genetics to the HLA genes has r

201 We addressed this deficit using principles of receptor silent substitution to present im

202 lack tea samples from Ceylon by applying the principles of sensomics.

203 were designed and implemented to protect the principles of solidarity and self-governance.

204 is no shortage of reviews on the fundamental principles of SRM and the remarkable achievements made w

205 The principles of the (sel)-SHARPER sequences are expected t

206 We use the principles of the conformational entropy model to engine

207 We also uncover underlying principles of the CRISPR-Cas adaptation system, includin

208 the review, we focus on the generic physical principles of the establishment of active mechanochemica

209 Computational modeling can reveal hidden principles of the system by classification of individual

210 of TAs have been used to discover the active principles of the TA polymers that interact with the inn

211 In this progress report, the operating principles of these sensors are reviewed, and different

212 nal and international guidelines outline the principles of treatment.

213 This Feature overviews the basic principles of using stable organic radicals involved in

214 tation exemplifies the trade-off between the principles of utility and medical urgency.

215 Here, the basic principles of various heterojunction photocatalysts are

216 and a summary of the evidence to support its principles offers guidance and a more systematic targete

217 nd through biotechnology and the engineering principles on which increased phytonutrient levels are b

218 olding-mechanistic behaviors, and the design principles orchestrating the signal transduction roles o

219 ic inhibitory polypeptide (GIP), as proof-of-principle peptides to demonstrate the value of thioamide

220 In summary, the principle phenotype of MBC was luminal A, ductal, grade

221 As a proof of principle, PLSR was used to build soil-bacterium compati

222 cture following habitat modification are, in principle, predictable.

223 n entirely different regions, illustrating a principle predicted from efforts in de novo protein desi

224 hich they believe is better aligned with the principles promoted by the IOM.

225 n summary, these findings provide a proof-of-principle, rational strategy to target the MYB "addictio

226 Here, we provide an overview of fundamental principles, recent discoveries, and clinical implication

227 stage for in-depth analyses of the molecular principles regulating the fascinating developmental cycl

228 cess can be treated as science whose unified principles remain true regardless of the stationary phas

229 These proof of principle results open a pathway for directing engineere

230 Although genome sequencing in principle reveals all genetic variants, their sizeable n

231 amaterials is reviewed, with emphasis on key principles, salient features, and potential limitations

232 The principles, sensitivity, selectivity and challenges of e

233 This general principle should be applicable to resolving many other r

234 en changing the excitation energy, and first-principle simulations confirm that such bands arise from

235 t study shows that children comply with both principles since their first grade of primary school.

236 n, Enquist (WBE) model argues that these two principles (space-filling and energy minimization) are (

237 Here we perform first-principles studies to investigate the influence of vacan

238 y using AAV vectors and showed in a proof-of-principle study how this virus-host interaction can be e

239 This proof-of-principle study introduces a sensing mechanism for singl

240 In this physiologic proof-of-principle study, we determined whether transfusion could

241 To test this concept, in this-proof-of-principle study, we screened for modulators of the inter

242 In our proof-of-principle study, we used comparative flow cytometric scr

243 The tool incorporates visualization design principles such as focus+context and visual data fusion

244 omise even more progress, with the hope that principled targeting of identified thalamic circuits can

245 But an outstanding question remains: what principle tells us which state variables to constrain?

246 care, and lower per capita cost-that is the principle tenet of healthcare system reform.

247 This study provides additional proof of principle that an apelin receptor agonist may be of ther

248 These results provide a proof of principle that can inform prospective vaccine developmen

249 provides fundamental insights into a general principle that confers the substrate binding adaptabilit

250 scuss ribosome homeostasis as an overarching principle that governs the sensitivity of specific cells

251 Notably, we provide proof-of-principle that inhibiting IP3R3 degradation in PTEN-dere

252 We do, however, highlight a therapeutic principle that provides a glimmer of hope: cellular post

253 This also provides a proof of principle that suboptimal CD8 T cell in old organisms ca

254 human material provide preclinical proof-of-principle that validates uPA as a novel therapeutic targ

255 xpressing (CRF-OE) mice to test the proof of principle that when CRF is in excess, sex-biased CRF1 co

256 , social mobilization refers specifically to principles that can be used to influence a large number

257 Learning from the design principles that defined success for the clinically-used

258 rons have traditionally emphasized empirical principles that describe nonlinear interactions between

259 odical consideration of the natural laws and principles that determine the phenomena occurring during

260 Focusing on principles that enable new levels of functionalities (te

261 cs) to elucidate the fundamental, underlying principles that govern the device characteristics, in pa

262 n skin and broadly informs on the prevailing principles that govern the tug-of-war between evolutiona

263 However, the physical and chemical principles that govern these interactions remain unclear

264 interactions from Hi-C to probe the guiding principles that link the spatial organization of the gen

265 inate and subsequently evolve the organizing principles that qualify them as new units.

266 of cultural inheritance echo a suite of core principles that underlie organic Darwinian evolution but

267 What are the principles that underlie these observed patterns?

268 This advisory serves to lay out a set of principles that will guide association engagement in pur

269 For proof-of-principle, the clinically relevant glucagon-like peptide

270 nanocrystals (PNC) to illustrate the working principle, the lasing threshold is found to be approxima

271 First-principles theoretical calculations are of limited appli

272 materials for these applications because, in principle, they are infinitely deformable while retainin

273 cherichia coli appear to share an invariance principle to coordinate growth and chromosome replicatio

274 c system, we use the stochastic least-action principle to derive the entropy production and its role

275 Engineered T cells are applicable in principle to many cancers, pending further progress to i

276 ing realistic root geometry and formulated a principle to theoretically investigate quantitative auxi

277 p model is developed using engineering first-principles to calculate mass and energy balances for eac

278 ake advantage of some set of physical design principles to ensure robust vesiculation against opposin

279 oid-based approach using basic developmental principles to generate large numbers of bonafide hair ce

280 cent advances in the application of economic principles to operant tasks in rodents have allowed for

281 The application of first principles to our data shows that conductive areas scale

282 e focus on: (1) attempts to formulate design principles to tailor active particles; (2) attempts to d

283 haps clarifying our understanding of network principles underlying motor behaviors in numerous organi

284 The principles underlying rate acceleration and enantiocontr

285 ing and energy minimization) are (i) general principles underlying the evolution of the diversity of

286 to clear endogenous mannosylated proteins, a principle used to endow insulin analogs with glucose res

287 framework for classifying the current first-principles vdW methods based on the adiabatic-connection

288 ferred from experimental data, in a fast and principled way.

289 As our first proof-of-principle we employed the bacterial chemotaxis protein C

290 As a proof of principle, we acquired 4D (H)COCANH, (H)CACONH, and (H)C

291 As proof of principle, we assembled genomes of the pigeon (Columbia

292 As proof of principle, we demonstrated that inactivation of a non-es

293 To reveal its working principle, we determined the nascent chain-binding patte

294 To demonstrate proof-of-principle, we used the TRBO-sgRNA delivery platform to t

295 Applying these principles, we describe the pattern of countershading in

296 Here, using heat transfer and thermodynamics principles, we show how Bui et al's conclusions about th

297 of collective cellular movements from first principles, while accounting for known phenomenological

298 Following these principles, WHO recommended that designated monitors in

299 easingly sophisticated models based on these principles will help to overcome some of the obstacles o

300 years from theoretical to clinical proof of principle with the publication of a first-in-man phase I