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2 ty of the trifluoromethylated nucleotides as probes for (19)F NMR-based real-time enzymatic reaction
7 titis B virus (HBV)-infected human livers to probe for a subset of T cells specialized to overcome lo
10 one application called ProbeDealer to design probes for a variety of multiplexed FISH techniques and
11 crease access to wireless optofluidic neural probes for advanced in vivo pharmacology and optogenetic
12 ard the next generation of optical molecular probes for advancing the understanding of lipid structur
13 ed oligonucleotide-based chromosome painting probes for all nine chromosomes in Citrus maxima (Pummel
17 PN hybrids can serve as not only sensitive probes for analyte recognition and signal generation/amp
18 of the liquid microjunction surface sampling probe, for analyzing the metabolome of live microglial c
19 s and increases the potential of fluorescent probes for applications in analytical chemistry and imag
22 rticles provide valuable benefits as optical probes for bioimaging and Forster resonant energy transf
24 rate that the inhibitor is not only a useful probe for biological studies of p300/CBP HAT but also a
25 are an attractive alternative to fluorescent probes for biological labeling because of their photosta
26 near-field spectroscopy and sensing, optical probing for biological systems and far-field beam synthe
27 nt challenges in the field of thiol-reactive probes for biomedical research and diagnostics, emphasiz
29 strated the usage of this dual-functionality probe for both flow cytometry and mass cytometry in a mi
32 he antiviral compound PF-3450074 (PF74) as a probe for capsid function, we uncovered a novel phenotyp
37 ologies such as dynamic protein profiling to probe for changes in rates of MPS and MPB at the individ
38 ecies across the boreal region in Finland to probe for changes in the beginning, end, and duration of
42 ersatility, thus offer high-contrast imaging probes for clinical diagnostics with compelling addition
43 Tyr-Au NPs were successfully used as a dual probe for colorimetric and fluorescence turn-on assays o
44 Here, we generated labeled SC(1-246) as a probe for competitively defining the affinities of N-ter
45 d for the development of an isoform-specific probe for CYP3A4, a key cytochrome P450 isoform responsi
46 inally, we demonstrated the utility of mEPIC probes for data exploration such as hierarchical cluster
48 lore their potential as novel ultrasensitive probes for deep-imaging of stress distributions in diver
49 ted high-throughput phenotypical platform to probe for defects in cardiogenesis and cardiac output in
52 our knowledge this is the first fluorescent probe for detecting AzoR activity in vivo, which can pro
55 review currently available molecular imaging probes for detecting fibrosis and fibrogenesis, the acti
57 s were used to develop a very high sensitive probe for detection Fe(3+), Cu(2+) ions and Cytochrome c
58 MASEBT) is a relatively recently synthesized probe for detection of amyloid fibrils accumulating in t
60 ated as an extremely sensitive and selective probe for detection of common ROS and RNS (i.e., H(2)O(2
62 ymers were demonstrated as chemiluminescence probes for detection of different chemical analytes.
63 ights are much needed to advance RNA imaging probes for detection of exo- and endogenous RNA and for
65 robe, double-hairpin probe and hybridization probe for different small ncRNA detection methods, can b
66 In this work, we present a new fluorescence probe for direct detection of methanol in aqueous and et
68 th a methylene blue (MB) reporter-tagged DNA probe for DNA target detection as a model system to stud
70 a kinome-wide selective radioactive chemical probe for endogenous kinase PET neuroimaging in human.
72 AST), a novel statistical hypothesis test to probe for enriched network colocalization in 2D z-projec
74 on for long-term monitoring with submersible probes for environmental analysis are possible analytica
76 1-(13)C]-glycerate ([(13)C]-Glyc) as a novel probe for evaluating glycolysis using hyperpolarized (13
78 e of action suggests that it may be a useful probe for examining energy metabolism, particularly in B
79 ating insula function, and could be a useful probe for examining interoceptive dysfunction in psychia
80 iants defined a range of NGS that we further probed for exclusive combinations of sequons in the HMP
82 nd expands the repertoire of pharmacological probes for exploring the function of Na(V) channels.
85 nable diverse applications of SWIR molecular probes for fluorescence microscopy using conjugates of a
86 fabrication of atomic force microscopy (AFM) probes for force spectroscopy using robust diamond-coate
89 inhibitors present an alternative biological probe for further determining the clinical utility and s
90 interaction and suggest that 2 is a valuable probe for further structural and chemical biology approa
96 thermore, the existing luminescent molecular probes for H(2)S cannot monitor it continuously due to t
97 or not only developing future supramolecular probes for HCh(-) binding and detection, but also for un
98 le compound 22 will be a useful experimental probe for helping to elucidate the role of ERbeta in can
99 We demonstrated the applicability of these probes for high-fidelity, noninvasive imaging of caspase
100 cation of HA using an anti-HA antibody and a probe for histidine decarboxylase (HDC), a synthetic enz
101 and synthesis of the first chemiluminescent probe for HNO, HNOCL-1, which can detect HNO generated f
104 imensional gel elements with target-specific probes for identifying mutations in katG, inhA promoter,
106 cterize a positron emission tomography (PET) probe for imaging DIPG in vivo In human histological tis
108 sion: (18)F-OF-NB1 is a highly promising PET probe for imaging the GluN2B subunits of the N-methyl-d-
109 zyl linker was applied to design fluorescent probes for imaging caspase-3/7 and beta-galactosidase ac
110 erate the preparation of new chemokine-based probes for imaging immune cell function in tumours.
111 ble chemokines as highly specific functional probes for imaging subpopulations of immune cells in liv
112 xample, these sensors can be integrated into probes for implantation, and then yield new and valuable
114 s strategy to produce mCCL2-MAF as the first probe for in vivo detection of metastasis-associated mac
117 erting nanocrystals as promising fluorescent probes for in vivo imaging in this spectral region.
118 d nanoclusters (AuNCs) have emerged as agile probes for in vivo imaging, as they exhibit exceptional
123 ons (MBs) have recently emerged as efficient probes for interrogating biomarkers in live cancer cells
124 ances, researchers can construct tailor-made probes for interrogating multivalent interactions with a
127 og pathway is expected to provide a valuable probe for investigating and targeting ligand-dependent h
129 , our work not only creates highly sensitive probes for investigating sub-nanomolar Zn(2+) dynamics,
130 orce interactions and may provide a valuable probe for investigations under harsh conditions but also
133 id modifying trans-cycloocten-5-ol (SAM-TCO) probes for labeling sulfenic acid functionality in live
134 filing, which makes use of covalent chemical probes for labeling the active site and detection by var
135 sed as baits for gene panel analysis or even probes for large-scale comparative genomic hybridization
136 ation can be used as a powerful atomic-scale probe for light-matter interactions and for properties o
137 scuss the role of small-molecule fluorescent probes for live-cell super-resolution microscopy and the
139 ored for use as alkyne-state-dependent Raman probes for living cell imaging due to synergetic enhance
140 quadruplex nucleic acids, providing valuable probes for local structure, dynamics, and ligand binding
141 properties of the neutron, which is an ideal probe for locating hydrogen positions and experimentally
142 e substrates for stem cells, and fluorescent probes for long-term tracking of cells and biomolecules
144 h-contrast, and clinically relevant cellular probes for many in vitro and in vivo biomedical applicat
145 Therefore quenched FeRh makes for an ideal probe for mapping a materials structural phase transitio
146 high resolution in vivo using a fluorescent probe for matrix metalloproteinase-2/9 activity, fluores
147 programmable material building blocks and as probes for measuring and manipulating intracellular proc
149 stimulated Raman scattering (SRS) imaging to probe for metabolic differences between fluconazole-susc
151 s, the availability of selective fluorescent probes for mitochondria could play an important role in
152 ture perspectives are aimed at using A9 as a probe for molecular imaging diagnostics as well as activ
154 adly useful for the development of substrate probes for monitoring exo-glycosidases, as well as a ran
155 the N-terminal residues of apoA-I as useful probes for monitoring formation and remodeling of HDL pa
159 Y4-yne, that serves as a cellular engagement probe for MPC2 in click chemistry-enabled western blotti
160 h as the iRFP series, have become invaluable probes for multicolor fluorescence microscopy and in viv
161 ration of miRFPs should become versatile NIR probes for multiplexed imaging across spatial scales in
163 used fluorescent in situ hybridization with probes for nascent transcripts to determine how soon aft
164 en available for decades, the development of probes for noninvasive detection of intracellular calciu
165 s proof-of principle study provides valuable probes for NTMT1/2 and highlights the opportunity to dev
166 ing GTNPs@PANI nanoparticles as the contrast probes for OCT imaging, noninvasive and real-time molecu
167 tinine, carnitine, and metformin, which is a probe for OCT1 and OCT2 and MATE1 and MATE2K (multidrug
168 s, using a highly selective affinity peptide probe for "OFF-ON" detection of Escherichia coli as a mo
169 oward this end, we produced whole-chromosome probes for P. roberti (PRO; 2n = 30 /NFa = 54) and P. go
172 is behavior enhances the selectivity of this probe for phase recognition, since the different environ
173 ign and synthesis of a targeted, activatable probe for photoacoustic imaging, which is responsive to
174 r dye quantum behavior, leading to efficient probes for photodynamic therapy (PDT) and stochastic opt
176 for the development of high-contrast imaging probes for potential use in clinical cancer diagnostics
180 zed metallic nanoparticles have been used as probes for protein tracking and drug delivery because of
182 comparable or even superior performance as a probe for PSMA-targeted RGS and also hint toward the une
183 ically deposited PDA resulting in functional probes for quantitative electrochemical adhesion studies
184 NA functionalized silver nanoparticle (AgNP) probes for quantitative investigation of biorecognition
185 mycin was developed as a diazirine-based PAL probe for rapamycin, and the FKBP12-photo-rapamycin-FRB
187 dous progress in the research of luminescent probes for reactive oxygen species (ROS), designing lumi
188 92 hemagglutinins (HAs) were constructed and probed for reactivity with ferret antisera against MN/10
189 velopment of a bioluminescent glucose-uptake probe for real-time, non-invasive longitudinal imaging o
196 demonstrated by using the AuNRs as embedded probes for selective surface-enhanced Raman spectroscopy
198 the surface-enhanced Raman scattering (SERS) probes for sensing transduction; and a functionalized fi
199 on of neutralized chimeric DNA oligomer as a probe for sensitive detection of single nucleotide polym
201 N-Cyclopropyl-N-methylaniline (5) is a poor probe for single electron transfer (SET) because the cor
203 rve as molecular high-contrast photoacoustic probes for single-cell diagnostics and as photothermal a
204 hesis, and evaluation of fluorescent flipper probes for single-molecule super-resolution imaging of m
205 ologies, and exploit emerging QDs as optical probes for spatial-temporal molecular imaging at greater
206 sed turn-on near-infrared (NIR) fluorescence probe for specific detection of beta-amyloid (Abeta) agg
209 These new BTD-based ligands are promising probes for spectral imaging of different Abeta fibril po
210 nucleoprotein, double stranded RNA, and RNA probe for spike genes were evaluated for the ability to
211 satile behavior of our synthesized phosphane probe for Staudinger peptide ligation toward synthesizin
213 triene (DPH) is a commonly used fluorescence probe for studying cell membrane-lipids due to its affin
214 signate this compound as a suitable chemical probe for studying the biological functions of ABHD12-(l
217 ors of cancer targets are useful as chemical probes for studying cancer mechanisms and starting compo
218 oach could be used to design allele-specific probes for studying cellular functions of spastin isofor
219 e the unique capability of our SECM chemical probes for studying real-time metabolic interactions bet
220 linked glycosides that can serve as valuable probes for studying the role of glycosides in biological
221 rs and dual-color fluorescent activity-based probes for studying two of the three active catalytic su
222 features make the TBP@PFBT PDs an excellent probe for successful apoptosis imaging in live cells.
225 designed single-molecule molecular inversion probes for target selection and used next generation seq
226 p38alpha/beta that can be used as a chemical probe for targeting this particular inactive state of th
228 ermittently through the use of a fiber-optic probe (for the case of oxygen) and biochemical assays (f
229 propose that NI-42 (13-d) is a new chemical probe for the BRPFs suitable for cellular and in vivo st
231 ed informatics framework, which allows us to probe for the contribution of equilibrium fluctuations t
232 desthiobiotin-conjugated LPA acyl phosphate probe for the covalent labeling, enrichment, and subsequ
233 brid, which allows for the construction of a probe for the detection of CN(-) in water samples and la
234 acetate) is the most widely used fluorogenic probe for the detection of general oxidative stress.
235 p water soluble, biocompatible nanocomposite probe for the detection of pyrophosphate (PPi) in physio
236 s work demonstrates that TMP is an effective probe for the determination of Rf,T and AQYT in whole wa
239 e, we present the development of a selective probe for the immunoproteasome, a specialized isoform of
240 and will serve as a useful in vivo molecular probe for the investigation of the roles of the MC3R and
241 of the analyzed sample and a microelectrode probe for the localized electrochemical analysis of the
242 he possibility of using A9 as HER2- specific probe for the nuclear medicine imaging was evaluated by
243 Herein, we report GSK4027 as a chemical probe for the PCAF/GCN5 bromodomain, together with GSK40
244 s at a given applied force to quantitatively probe for the phase state as a function of RH and corres
246 Ds could be used as a sensitive fluorescence probe for the quantification of different concentrations
247 This technique can be used as a microscopic probe for the quantitative in situ tracking of retrograd
248 In this work, we designed a peptide-based probe for the rapid (<10 min) high-throughput survey of
250 idization of the target miRNA with a capture probe for the recognition, which can be designed in eith
253 readout using a Universal DNA-Hairpin (UDH) probe for the selective recognition of an isothermally a
254 (18)F]FETrp may prove a valuable PET imaging probe for the Shh subgroup of medulloblastoma and possib
255 show that the novel Tpx-roGFP2 is a superior probe for the trypanothione redox couple and that the mi
256 We fabricated a membrane-based CoOxH-GO probe for the visual detection of CN(-) by preparing a t
257 work (MOF) = variable; guest = constant) was probed for the first time in comparison with previously
258 nt on the materials electronic structure was probed for the first time using novel purely organic por
259 the potential imprint of bias in science, we probed for the most commonly postulated bias-related pat
260 In particular, we discuss the chemistry of probes for the biomarkers, heat shock protein 10 and lys
265 ategy involving dual platforms and short DNA probes for the detection of endangered species, Malayan
267 les such as liposomes to be used as acoustic probes for the detection of very low concentrations of D
268 pment of metal-organic framework (MOF)-based probes for the direct and rapid detection and quantifica
269 based DNA binding proteins that can serve as probes for the direct, programmable recognition and anal
270 onstrate the value of chemically synthesized probes for the elucidation of the enzyme mechanism under
271 Comprehensively characterized fluorescent probes for the histamine H(3) receptor (H(3)R) and espec
272 lobalide would facilitate the development of probes for the identification of potential new targets,
273 the specificity of locked nucleic acid (LNA) probes for the in situ detection of multiple small RNAs.
274 psy, suggesting the potential of using these probes for the investigation of brain disorders such as
275 terostructures are presented as nanophotonic probes for the light-triggered photoelectrochemical dete
276 tallic core-shell nanocrystals are excellent probes for the local physicochemical conditions inside T
278 elements such as antibodies/antigens and DNA probes for the proposition of immunosensors and genosens
280 first GAG polysaccharide-based photoaffinity probes for the system-wide identification of GAG-binding
282 t activated affinity-switchable biotin (ASB) probes, for the detection of O(2)(-) and F(-), using ele
283 rimary kinetic isotope effect can serve as a probe for these mechanisms, as confirmed in virtually al
284 ingosine and diacylglycerol; uncaging of the probe for these two species triggered calcium signaling
285 yptophan (1-L-[(18)F]FETrp) as a PET imaging probe for this common malignant pediatric brain tumor.
289 ed rapid progression to potent and selective probes for two enzymes, the deubiquitinase OTUB2 and the
290 a distinct yet complementary set of imaging probes for understanding disease mechanisms in three dim
293 oughly investigated the suitability of these probes for use in electrochemical advanced oxidation pro
294 esigned a family of ratiometric endosomal pH probes for use in live-cell STED nanoscopy.Ratiometric f
295 of two new, near-infrared (NIR) fluorescent probes for use in the molecular imaging of bone repair.
297 methyl group in each pyrroline ring has been probed for utility in the synthesis of BChl a by prepara
298 e work also shows the possibility of using a probe for validating cleaning of hard to reach areas usi