ライフサイエンスコーパス: procarbazine

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1 o received chemotherapy containing high-dose procarbazine.

2 c agents: cyclophosphamide, mitomycin C, and procarbazine.

3 , at best, a few weeks longer than that with procarbazine.

4 treating the parent xenograft D-245 MG with procarbazine.

5 01), ifosfamide (0.42, 0.23-0.79; p=0.0069), procarbazine (0.30, 0.20-0.46; p<0.0001) and cisplatin (

6 ith five cycles of high-dose MTX 3.5 g/m(2), procarbazine 100 mg/m(2)/d, and vincristine 1.4 mg/m(2).

7 e 2 mg/m2 intravenously on days 1 and 8, and procarbazine 100 mg/m2 orally on days 1 to 14.

8 Procarbazine 100 mg/m2/d was administered for 7 days wit

9 nitrogen mustard in addition to omission of procarbazine and melphalan.

10 ents, risks and benefits of exposure to both procarbazine and subdiaphragmatic radiotherapy should be

11 Increasing the dose of MTX and adding procarbazine and vincristine improved disease control an

12 ; or VAMP/cyclophosphamide, vincristine, and procarbazine) and involved-field radiation therapy deliv

13 eived two cycles of vincristine, prednisone, procarbazine, and doxorubicin or vincristine, prednisone

14 les of methotrexate 2.5 g/m(2), vincristine, procarbazine, and intraventricular methotrexate (12 mg).

15 on as alternating chlorambucil, vinblastine, procarbazine, and prednisolone (ChlVPP) with prednisolon

16 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP baseline) or four

17 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP) had continuous am

18 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPPesc) and INRT (supe

19 e, the regimen of chlorambucil, vinblastine, procarbazine, and prednisone (ChlVPP) has been proposed

20 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (eBEACOPP) for six cycles.

21 emotherapy was mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) or procarbazine, mec

22 ned to compare mechlorethamine, vincristine, procarbazine, and prednisone (MOPP)/doxorubicin, bleomyc

23 and etoposide/mechlorethamine, vincristine, procarbazine, and prednisone (ProMACE[day 1]-MOPP[day 8]

24 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone at baseline over ABVD was n

25 e, etoposide, nitrogen mustard, vincristine, procarbazine, and prednisone in similar patient populati

26 , adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) followed by two cycles of

27 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone) has significantly improved

28 , adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) in the German Hodgkin Stud

29 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone) on the fertility of male p

30 apy with MOPP (mechlorethamine, vincristine, procarbazine, and prednisone), ABVD (doxorubicin, bleomy

31 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone), and six cycles of COPP-EB

32 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone).

33 doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone, menstrual activity was str

34 ess the efficacy of rituximab, methotrexate, procarbazine, and vincristine (R-MPV) followed by consol

35 y with rituximab, methotrexate (3.5 g/m(2)), procarbazine, and vincristine (R-MPV).

36 s of induction chemotherapy (rituximab, MTX, procarbazine, and vincristine [R-MPV]) as follows: day 1

37 specially over 10 Gy), alkylating agents and procarbazine, at older ages, were significant risk facto

38 A cumulative procarbazine dose of 4.3 g or more per square meter of b

39 to 46.6), after adjustment for radiation and procarbazine doses.

40 , high-dose methotrexate [MTX], vincristine, procarbazine) followed by a novel consolidation high-dos

41 ation to the stomach >/= 25 Gy and high-dose procarbazine (>/= 5,600 mg/m(2)) had strikingly elevated

42 iol treatment that protected the testis from procarbazine-induced damage.

43 strate here that giving a GnRH agonist after procarbazine injection also enhances spermatogenesis and

44 lts of this trial showed that treatment with procarbazine, lomustine (also called CCNU), and vincrist

45 Because procarbazine, lomustine (CCNU), and vincristine (PCV) is

46 y; range 54 to 55 Gy) and nitrosourea-based (procarbazine, lomustine [CCNU], and vincristine [PCV-3 r

47 regimens involving alkylating agents such as procarbazine, lomustine, and carmustine.

48 rapy-carboplatin, vincristine, temozolomide, procarbazine, lomustine, and thioguanine-at age 4.5 year

49 se III clinical trial investigating adjuvant procarbazine, lomustine, and vincristine (PCV) chemother

50 e III study on the addition of six cycles of procarbazine, lomustine, and vincristine (PCV) chemother

51 sted a progression-free survival benefit for procarbazine, lomustine, and vincristine (PCV) chemother

52 tients with AO/AOA were randomly assigned to procarbazine, lomustine, and vincristine (PCV) plus radi

53 our knowledge, the first randomized trial of procarbazine, lomustine, and vincristine (PCV) versus TM

54 51), the addition of neoadjuvant or adjuvant procarbazine, lomustine, and vincristine (PCV; respectiv

55 oplatin and vincristine (CV) or thioguanine, procarbazine, lomustine, and vincristine (TPCV).

56 stic oligodendroglioma patients treated with procarbazine, lomustine, and vincristine chemotherapy.

57 Both temozolomide and the combination of procarbazine, lomustine, and vincristine provide surviva

58 The addition of PCV (procarbazine, lomustine, and vincristine) chemotherapy t

59 th carboplatin followed by chemotherapy with procarbazine, lomustine, and vincristine.

60 ith those who received radiation < 25 Gy and procarbazine < 5,600 mg/m(2) (Pinteraction < .001).

61 eived radiation to the stomach >/= 25 Gy but procarbazine < 5,600 mg/m(2); however, no procarbazine-r

62 tine, procarbazine, and prednisone (MOPP) or procarbazine, mechlorethamine, and vinblastine (PAVe) in

63 thamine (nitrogen mustard), vincristine, and procarbazine (MOP) for recurrent glioma.

64 These agents include procarbazine, nitrogen mustard, melphalan, nitrosoureas

65 logues or steroids either before exposure to procarbazine or radiation or after irradiation enhances

66 doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) are maturing with promising re

67 doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) in children with high-risk HL

68 ine (ABVD) and mechlorethamine, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, and vi

69 of COPP/ABV (cyclophosphamide, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, vinbla

70 dacarbazine; cyclophosphamide, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, vinbla

71 ut procarbazine < 5,600 mg/m(2); however, no procarbazine-related risk was evident with radiation < 2

72 n addition to abdominal radiation, high-dose procarbazine (relative risk, 3.2 [CI, 1.1 to 9.4]) and p

73 tertile HR, 0.42; 95% CI, -0.31 to 0.57) or procarbazine (second tertile HR, 0.48; 95% CI, -0.26 to

74 D-245 MG xenografts were sensitive to procarbazine, temozolomide, N-methyl-N-nitrosourea, 1,3-

75 D-245 MG (PR) xenografts were resistant to procarbazine, temozolomide, N-methyl-N-nitrosourea, and

76 an, prednisone, epidoxorubicin, vincristine, procarbazine, vinblastine, and bleomycin; CEC) in patien

77 e sex ratio and the association observed for procarbazine warrant further investigation.

78 clophosphamide, vincristine, prednisone, and procarbazine were added in TG2 (intermediate stages) or

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