ライフサイエンスコーパス: proctolin

1 ropeptide-like precursors 2-4 (NPLP2-4), and proctolin.

2 at was statistically similar to that seen in proctolin.

3 ence of the responses elicited by CabTRP and proctolin.

4 projection neurons contain the neuropeptide proctolin.

5 the crab pyloric network by the neuropeptide proctolin.

6 In addition, occlusion experiments with proctolin, a different neuropeptide converging onto IMI,

7 n selection occurs during MPN activation via proctolin actions on the STG network and GABA-mediated a

8 eptidase activity in the STG that terminates proctolin actions, we tested the hypothesis that the dif

9 One of these peptides, proctolin, activates an inward current that shows strong

10 Proctolin additionally acts on the pyloric dilator (PD)

11 ed FLRFamide peptides, tyrosine hydroxylase, proctolin, allatostatin, serotonin, Cancer borealis tach

12 Proctolin also changes the power of the LP neuron resona

13 dition to direct modulation of this synapse, proctolin also changes the shape and amplitude of the pr

14 ented by continuous exogenous application of proctolin, an endogenous neuromodulatory peptide, to the

15 Proctolin and CCAP both act on the lateral pyloric neuro

16 The motor patterns produced in proctolin and CCAP differed quantitatively in a number o

17 ally compared the motor patterns produced by proctolin and CCAP.

18 oltage clamp to study the currents evoked by proctolin and five additional modulators [C. borealis ta

19 86 confers second messenger activation after proctolin application, with an EC(50) of 0.3 nM.

20 e membrane potential and is also enhanced by proctolin at all baseline potentials.

21 ns correlate with previous demonstrations of proctolin biological activity, and in several instances,

22 se rhythms contain GABA and the pentapeptide proctolin, but only MCN1 contains Cancer borealis tachyk

23 Six neuromodulators [proctolin, Cancer borealis tachykinin-related peptide Ia

24 e receptors for the Drosophila neuropeptides proctolin (CG6986), neuropeptide F (CG1147), corazonin (

25 n MCN1 or CPN2, although exogenously applied proctolin directly excites these neurons.

26 Proctolin enhances the graded component and unmasks a su

27 The waving of the fifth legs is modulated by proctolin in freely moving crabs and in reduced preparat

28 Proctolin-induced CD occurs with developmental and seaso

29 linearizes the current-voltage curve of the proctolin-induced current.

30 Proctolin is a bioactive neuropeptide that modulates int

31 ic rhythm is mimicked by bath application of proctolin, its peptide transmitter.

32 Subtraction currents yielded proctolin-like current-voltage relationships for all six

33 We also demonstrate that MPN has no proctolin-mediated influence on MCN1 or CPN2, although e

34 We show that proctolin modulates the spike-mediated and graded compon

35 wo identified projection neurons [modulatory proctolin neuron (MPN) and modulatory commissural neuron

36 ern selected by activation of the modulatory proctolin neuron (MPN) results from direct MPN modulatio

37 ion comes from the ability of the modulatory proctolin neuron (MPN), a projection neuron that suppres

38 mmissural neuron 1 (MCN1) and the modulatory proctolin neuron (MPN), contain the neuropeptide proctol

39 ntified projection neurons is the modulatory proctolin neuron (MPN).

40 include the previously identified modulatory proctolin neuron and modulatory commissural neuron 1 (MC

41 application of saturating concentrations of proctolin occluded the response to CabTRP and vice versa

42 mine, dopamine, acetylcholine, serotonin and proctolin) on cAMP distribution in identified neurons of

43 ity, and in several instances, with areas of proctolin peptide immunosignals.

44 tolin neuron (MPN), contain the neuropeptide proctolin plus GABA.

45 Proctolin receptor immunosignals are found in the hindgu

46 The identification of a bona fide proctolin receptor provides the basis for a mechanistic

47 n-coupled receptor CG6986 of Drosophila is a proctolin receptor.

48 During ongoing oscillations, proctolin reduces the variability of cycle period but on

49 ential actions of aminopeptidase activity on proctolin released from these two projection neurons.

50 Proctolin, serotonin, and allatostatin were also physiol

51 ivation curve by the modulatory neuropeptide proctolin shifts the frequency preference.

52 ion-based studies, the CG6986 receptor binds proctolin with high affinity (IC(50) = 4 nM).