ライフサイエンスコーパス: productive

1 overy and isolation efforts should be highly productive.

2 ority of PFV intasome search events were non-productive.

3 WUE with high growth rates, i.e., are water productive.

4 tend to stay in the herd longer and be more productive.

5 here C4 species might be expected to be that productive.

6 is a helper-dependent dependoparvovirus, and productive AAV2 replication requires coinfection with a

7 Based on these results, we suggest that productive acquisition of Ag may be one of the main fact

8 Quantitative imaging suggested that productive actin assembly initiation is tightly coupled

9 ion of the electron-rich dienophiles without productive activation of the electron-deficient heterocy

10 cts as a biocompatible support layer for the productive adsorption of the enzyme.

11 ytically deficient Trr eclose and develop to productive adulthood.

12 and wellbeing required to become healthy and productive adults.

13 plants accumulate more ABA and exhibit more productive agronomic traits during drought while OsOTS1

14 sm wherein the LRR domain selectively blocks productive aminolysis, but not the nonproductive dischar

15 ; alpha2betabeta'omegasigma(70)), we compare productive and abortive initiation rates, short RNA dist

16 OG processing in B cells from destructive to productive and facilitates cross-presentation of disease

17 study area for spruce and beech to maintain productive and healthy forests in the future.

18 , we carried out a comprehensive analysis of productive and nonproductive Ig gene rearrangements from

19 The data also identify the non-productive and productive paths of the HadA reactions an

20 rmation of families was associated with more productive and seasonal environments, where prolonged pa

21 his work identifies, for the first time, the productive and specific interactions of a collagen tripl

22 ther, our results suggest that when the most productive and stable monoculture is unknown, inoculatin

23 r Jordan Valley where wild cereals were more productive and stable.

24 Diatoms are one of the most productive and successful photosynthetic taxa on Earth a

25 A particularly productive area of study is on single layer epithelial t

26 2.3% of shelf which are shallows could be as productive as all the remaining continental shelf.

27 land that will be lost is more than twice as productive as national averages.

28 litate and guide the maturation process into productive assembly branches in and across different cel

29 high frequency, generates diverse and highly productive assembly lines.

30 ent learning (RL) theory has been remarkably productive at improving our understanding of instrumenta

31 a druggable target whose inhibition enhances productive autophagy and mHtt proteolysis, revealing a u

32 erfering with Ubp3/USP10 function could be a productive avenue in the development of novel cancer the

33 nvolving GAS pathogenesis, and that the most productive avenues for research going forward may be inv

34 findings, we suggest that PABP enhances the productive binding of the eRF1-eRF3 complex to the ribos

35 2B-Ub physically 'corrals' the enzyme into a productive binding orientation.

36 terio)chlorophyll pigments is among the most productive biological pathways on Earth.

37 f C exchange with the atmosphere in the most productive biome on earth.

38 of APOBEC3B has little short-term effect on productive BKPyV infection, our informatics analyses ind

39 Although productive, both strategies suffer from intrinsic limita

40 Productive budding events required at least two addition

41 Thus, the autotrophic productive capacity of large aquatic ecosystems may be r

42 h is akin to a protein fold, is critical for productive catalysis since peptides possessing the same

43 /[Ph3C][B(C6F5)4] yields a highly active and productive catalyst system for the convenient synthesis

44 e (5'-P) binding pocket, which can favor the productive catalytic complex assembly and enhance the dG

45 lat film surface, or cracks) responsible for productive chemistry in these materials.

46 3) subsequent dispersals from the Yucatan to productive coastal areas in the Gulf of Mexico, the Cari

47 ion to address the global challenge of OA in productive coastal systems.

48 , and government will lay the foundation for productive collaboration and a sustainable pediatric onc

49 es closely resembled that of the single most productive community grown in isolation.

50 The Southern Ocean houses a diverse and productive community of organisms.

51 staff and a focus group with members of the Productive Community Services implementation team were a

52 the implementation, and four members of the Productive Community Services Implementation Team.

53 an implementation of the first module of the Productive Community Services programme called 'The Well

54 interactions fine-tunes the lifetime of the productive complex and hence the likelihood of Gag prote

55 formation of a transient, sparsely populated productive complex between protease and Gag substrates.

56 A productive complex can also be formed in the presence of

57 The collagenolytically productive complex forms by utilizing seven distinct sub

58 ity and thereby increasing the population of productive complexes containing two PKRs bound to a sing

59 that prevents cellular RNAs from generating productive complexes that can signal.

60 MD simulations reveal that productive concerted trajectories display a strong angle

61 rom the substrate stabilizes the enzyme in a productive conformation to facilitate macrocyclization o

62 This achieves preorganized, productive conformations.

63 ng, through the sampling of many potentially productive conformations.

64 m was found to be position independent and a productive contributor for the ligand-enzyme complex sta

65 that this cancer-associated mutation affects productive cosubstrate binding in ALKBH7.

66 s (often persistent) including dyspnea and a productive cough.

67 nked 1st, 3rd and 4th respectively among the productive countries.

68 tractable transition from its latent to its productive cycle in cell culture.

69 e adduct to be a genuine intermediate on the productive cycle toward catalysis.

70 hted represent not only unusual instances of productive deep-seated natural product modifications and

71 mpatible with the goal of maintaining highly productive deer populations.

72 ocarcinoma and HuH-7 hepatoma cells, and for productive DENV infection of Aedes aegypti mosquitoes.

73 change prior to HJ cleavage: formation of a productive dimer on the HJ.

74 activate natural cassette exons by promoting productive docking of the spliceosomal U1 snRNP to a sub

75 ew controlled drug delivery systems was very productive during the period 1950-1980.

76 s threatens the future of our field, as many productive early and midcareer scientists are facing hav

77 ulence, as nonengrafted mice did not support productive EBOV replication or develop lethal disease.

78 Our study area is Chesapeake Bay, a highly productive ecosystem providing natural resources, transp

79 atches in the East China Sea-one of the most productive ecosystems in the world that has also had its

80 that the role of biodiversity in maintaining productive ecosystems should figure prominently in globa

81 effects of LMH on consumer abundance in more productive ecosystems.

82 teful energy dissipation by diversion of the productive electron transfer pathway through the generat

83 omoters to facilitate P-TEFb recruitment and productive elongation in response to stimulation.

84 The release of paused RNA polymerase II into productive elongation is highly regulated, especially at

85 tion complex assembly and disassembly before productive elongation of Pol II is achieved at most gene

86 , mechanisms regulating transcription during productive elongation remain poorly understood.

87 cruitment and release from the promoter into productive elongation, but how specific chromatin regula

88 nd attenuates host gene transcription during productive elongation.

89 modulates the release of paused Pol II into productive elongation.

90 the +2 nucleosome and reduced transition to productive elongation.

91 anscription initiation site before beginning productive elongation.

92 NAPII, a key rate-limiting step required for productive elongation.

93 ruited late-phase CME proteins and supported productive endocytosis, identifying it as an Ede1 functi

94 ral and functional rearrangements needed for productive engagement of circulating platelets, resultin

95 cation being rate-limited by recognition and productive engagement of peptidyl-tRNA within the P site

96 ndicate that domesticated landraces of maize productive enough to be a staple grain existed in Centra

97 B.P.), but it remains unclear when maize was productive enough to be a staple grain in the Americas.

98 pulations inhabiting both relatively stable, productive environments and in populations living under

99 t more animal consumption in N-poor and more productive environments respectively, failed to vary wit

100 redict more animal consumption in N-poor and productive environments respectively.

101 rges when family living is favored in highly productive environments, followed secondarily by selecti

102 folded protein response (UPR), to maintain a productive ER protein-folding environment through reprog

103 sic investigation: pressure to be clinically productive, excessive administrative responsibilities, d

104 why higher amylolytic activity prolonged the productive fermentation time only.

105 The results suggest that this is a very productive fishery and that survivability of returns fro

106 ome peptides, nonnative contacts can lead to productive folding events.

107 ates polypeptides that are in the process of productive folding from conformers that are trapped in a

108 nd biological functions, and are crucial for productive folding of many glycoproteins.

109 western United States were greener and more productive following winters with south-shifted storm tr

110 reactant complex, only a subset of which are productive for bi- (or larger) cyclization and lead to p

111 n of polymerase pausing generally limits the productive frequency of transcription initiation in huma

112 h mice infected with these strains developed productive genital tract infections.

113 cell energy-sensing program to support viral productive growth irrespective of physiological stress.I

114 pecies may redistribute to new, suitable and productive habitats.

115 Productive high-energy charge-transfer (CT) states are p

116 Cac2 is indispensable for productive histone binding, while deletion of Cac3 has o

117 scrimination of drug-induced reactivation of productive HIV based on protein expression.

118 mory/effector differentiation as well as for productive HIV infection.

119 d CD4(+) T cells were measured as markers of productive HIV infection.

120 motes the capacity of CD4 T cells to support productive HIV replication.

121 type I IFN-inducible CD169 could facilitate productive HIV-1 infection in myeloid cells in cis and C

122 e exact mechanisms causing HAND are unknown, productive HIV-1 infection in the brain with associated

123 V-K expression in the presence or absence of productive HIV-1 infection of primary human CD4(+) T cel

124 mediated indirectly, owing to the absence of productive HIV-1 replication in cardiomyocytes.

125 Productive HspQ-Lon engagement enhances degradation of m

126 Productive HSV infection colocalized with these receptor

127 etermine if stress-related hormones modulate productive HSV-1 and HSV-2 infections within sensory and

128 addition, the impact of low-energy stress on productive HSV-1 growth and viral genetic determinants p

129 r bodies, an intracellular event critical to productive HSV-1 infection that is initiated by interact

130 These neuronal cells are able to support a productive HSV-1 infection, with kinetics and overall ti

131 Productive humoral responses require that naive B cells

132 specifically required to drive the levels of productive IE mRNAs.

133 rogate L chain is necessary for selection of productive IgH gene rearrangements.

134 combination (CSR) diversifies antibodies for productive immune responses while maintaining stability

135 the lymphocyte reservoir necessary to mount productive immune responses.

136 nnate and adaptive immune cells required for productive immunity.

137 rning prediction methods have been extremely productive in applications ranging from medicine to allo

138 We expect this field to remain vibrant and productive in its own right and as part of a wider inqui

139 Myeloid infection was productive in some settings but was efficiently suppress

140 nuclear translocation pattern that promotes productive infection and avoids viral degradation, sugge

141 ng reactivation and cooperatively stimulated productive infection and IEtu1 GREs in mouse neuroblasto

142 of trigeminal ganglia (TG), cycling between productive infection and latency.

143 ticoid receptor (GR), cooperate to stimulate productive infection and viral transcription.

144 s cooperate on the virion surface to mediate productive infection by HIV-1.

145 rmined how impairment of endocytosis affects productive infection by prion strains 22L and RML.

146 op that stimulates viral gene expression and productive infection following stressful stimuli.IMPORTA

147 nimals were completely protected compared to productive infection in all seven DM-vaccinated animals.

148 is a ubiquitous human pathogen, which enters productive infection in human epithelial and many other

149 To establish a productive infection in humans, DENV uses different stra

150 Both influenza A-like viruses established a productive infection in MDCK II cells; however, HL18NL11

151 ritic cells (DCs) en route to establishing a productive infection in T lymphocytes but fails to induc

152 ensure subsequent reverse transcription and productive infection in target cells.

153 ilitate subsequent reverse transcription and productive infection in target cells.

154 ble of transmitting infection and triggering productive infection in tissue.

155 stically stimulate viral gene expression and productive infection may be critical for the ability of

156 tted most efficiently from cell to cell, and productive infection occurs mainly in activated CD4 T ce

157 CD4 T cells are susceptible HIV targets, and productive infection of CCR7(hi) memory T cells did not

158 s of infected pigtailed macaques, suggesting productive infection of CD169(+) cells in vivo Treatment

159 calization of p27(gag) and CD169, suggesting productive infection of CD169(+) myeloid cells in vivo W

160 For example, the capacity for efficient productive infection of cultured cells by herpes simplex

161 BocaSR genes, HBoV1 NS2 is required for the productive infection of HEK293 and HeLa cells by AAV2, w

162 Quantitative analyses revealed preferential, productive infection of neural progenitors with either A

163 At least one VZV sncRNA was expressed in productive infection of neurons and fibroblasts that is

164 ) express HIV-1 transcripts, suggesting that productive infection of renal epithelial cells precipita

165 2 target a common set of substrates vital to productive infection of this large cytoplasmic DNA virus

166 During the productive infection of tumor-associated gammaherpesviru

167 We observed low-level productive infection on exposure of these cells to prima

168 virus (PRV) throughout a 12-hour interval of productive infection on PK-15 cells.

169 tion but also reverses latency, resulting in productive infection that generally leads to cell death.

170 e that HHV-8 can target both LC and iDDC for productive infection via different receptors and alter t

171 t cord blood CD34(+) cell precursors support productive infection with HHV-8.

172 The Egyptian rousette develops subclinical productive infection with MARV but is refractory to EBOV

173 i virulence determinant that is required for productive infection within vertebrate, but not tick, ho

174 strategy for lifelong persistence, involving productive infection, latency, and intermittent reactiva

175 Thus, to establish a productive infection, virions must be stable in the envi

176 -1 particles from early entry events through productive infection, we developed a method to visualize

177 ients and adenosine triphosphate (ATP) for a productive infection.

178 d they stimulate certain viral promoters and productive infection.

179 even a single virus particle can initiate a productive infection.

180 bs this balance has the potential to block a productive infection.

181 lex virus 1 (HSV-1) results in a delayed but productive infection.

182 m, which is essential for establishment of a productive infection.

183 gamma irradiated the cells to prevent their productive infection.

184 this host RNA decay machinery to establish a productive infection.

185 ly regulated and sequentially ordered during productive infection.

186 X-2 activation and does not result in a full productive infection.

187 n and how these changes in the virus lead to productive-infection events.

188 To establish productive infections, viruses must counteract numerous

189 modulate host immune defenses and establish productive infections.

190 es the pause duration but also increases the productive initiation frequency.

191 Productive integration into host chromatin results in th

192 Splicing is initiated by a productive interaction between the pre-mRNA and the U1 s

193 rical work has combined to generate a highly productive interaction involving successive developments

194 minant that significantly contributes to the productive interaction of Tat precursor proteins with th

195 charged RNA binding cleft that is primed for productive interaction with RNA targets, potentially exp

196 th myoVa-HMM and full-length myoVa-Mlph from productive interactions.

197 particles, which may trigger uptake into non-productive internalization pathways in target cells, did

198 Collectively, these observations suggest a productive interplay between physical properties of mous

199 inflammatory Ly6C(hi) monocytes served as a productive intracellular growth niche for L. monocytogen

200 To determine the metabolic requirements for productive KSHV infection, we induced lytic replication

201 y, these results establish the occurrence of productive L1 mobilization in the absence of an intact p

202 O in CO2 equivalents) emitted from a shallow productive lake during an average versus a heat-wave yea

203 otypes to selectively breed stronger or more productive livestock and crops.

204 ll continents, cultural diversity is high in productive low latitudes, presumably because such region

205 ir biphasic life cycle-viral latency and the productive lytic cycle-and it is well established that r

206 promoting lytic replication.IMPORTANCE KSHV productive lytic replication plays a pivotal role in the

207 1 (HSV-1) latency entails the repression of productive ("lytic") gene expression.

208 rategy for the first time and shown to allow productive macrocyclization at concentrations up to 200

209 arbene and elicit C-C coupling products in a productive manner.

210 the Ghaggar-Hakra-Nara, probably sustained a productive marine environment as well as navigability to

211 broblasts as natural host cells that support productive MCPyV infection.

212 how that dominant screens are a feasible and productive means to identify mutations that can further

213 upport for counterion-mediated uptake as the productive mode of action of arginine-rich CPPs.

214 or crown gall disease of plants has proven a productive model for many aspects of interactions betwee

215 Interspecific mixtures outperformed the most productive monocultures in only 10% of the cases, compar

216 dominated estuaries serve as one of the most productive natural ecosystems through their ecological,

217 nds, which are among the most biodiverse and productive of any environments and which provide essenti

218 Oil palm is the most productive oil crop in the world and composes 36% of the

219 nfluenza virus replication in macrophages is productive or abortive has been a topic of debate.

220 DJH intermediates and V(D)J exons in either productive or nonproductive configurations.

221 nally inactive as there was no evidence of a productive or transforming infection.

222 But the complementary views lead to productive overlap in atomic theory.

223 ase with which we have discovered robust and productive oxygen activation catalysts suggests that the

224 infections are unknown, it is believed that productive pathogen replication is required.

225 he data also identify the non-productive and productive paths of the HadA reactions and demonstrate t

226 lasminogen (Plg)/plasmin (Pla) system in the productive phase of inflammation is well known, but its

227 ors play in transitioning paused Pol II into productive Pol II is, however, little known.

228 ize an off-pathway swapped dimer, preventing productive pore formation.

229 more global, isotope-independent search for productive protein conformational sub-states.

230 he MYW cofactor radical but could reduce non-productive protein-based radical species that accumulate

231 substrate specificities dependent upon both productive protein-carbohydrate interactions across a bi

232 etween the distribution of nonproductive and productive rearrangements that reflect the impact of sel

233 Even the CDRH3s in the productive rearrangements were shorter in length than th

234 DJH recombination with a severe reduction in productive rearrangements, which directly corresponded t

235 ter in length than those of the normal human productive repertoire.

236 may promote viral latency (in PEL cells) and productive replication by limiting the damaging effects

237 r in CMG activation, increases the number of productive replication events in our assay.

238 l viability and proliferation and also viral productive replication in PEL and endothelial cells.

239 o either maintain a latent state or initiate productive replication in response to host cues.

240 s expand upon this work and demonstrate that productive replication is not specific to unique HPAI H5

241 hether transfer via this route can result in productive replication of the infectious agents in the r

242 different stages of the viral life cycle or productive replication on macrophage function, we assess

243 tress as infected cell protein synthesis and productive replication were reduced compared to levels i

244 undergo homologous recombination (HR) during productive replication, often leading to wild-type (WT)

245 nant virus remained completely defective for productive replication, providing a high degree of safet

246 ne or paracrine mechanisms during latency or productive replication.

247 s such as herpes simplex virus 1 (HSV-1) for productive replication.

248 ng that the early steps are not limiting for productive reprogramming.

249 , is transiently induced in cells undergoing productive reprogramming.

250 lar dNTP pool to a level that cannot support productive reverse transcription.

251 ggesting that defect-ordered MOFs could be a productive route to porous two-dimensional materials.

252 With respect to the needs of productive screening systems for robust and reproducible

253 (HBeAg), HBsAg was not a reliable marker of productive sHBV infection at early time points.

254 age, and concentrates production on the most productive sites and consequently lowers food prices.

255 Thus, Vps33/HOPS promotes productive SNARE assembly in the presence of otherwise i

256 losed Munc18-1:syntaxin complex, followed by productive SNARE complex assembly and vesicle priming.

257 ecies to current prevalence of smaller, more productive species often of low commercial value.

258 tonomous process that may be mediated by the productive spreading of prion-like protein aggregates fr

259 V persistence comprises latent, chronic, and productive states that may occur concurrently.

260 ies toward less diverse and potentially less productive states.

261 t macrocyclic cinnamate dimers combine these productive stress-responsive modes.

262 heir target using alternate poses may enable productive structure-based optimization along multiple d

263 This effect could be explained by productive substrate binding that protects LPMOs from ox

264 ormation to an open conformation to initiate productive substrate binding.

265 is endangered species, and serve as model of productive synergy between ecological monitoring and con

266 nto the ribosome and bound to Pro-tRNA(Pro), productive synthesis of the peptide bond occurs.

267 To stimulate a productive T cell response, dendritic cells (DC) must un

268 s-fixing soils and achieve yields similar to productive temperate agriculture.

269 cognition is both more parsimonious and more productive than assuming the opposite.

270 References Flowering plants can be far more productive than other living land plants.

271 0.4 g AFDW.m(-2).d(-1)) were 1.20 times more productive than the corresponding controls without CO2 s

272 ke place on cropland that is 1.77 times more productive than the global average.

273 n viruses, network analysis methods are more productive than traditional phylogenetic approaches.

274 tify important principles that contribute to productive thiol oxidation in complex, crowded, dynamic

275 issue with monocyte-attached HIV resulted in productive tissue infection.

276 owing it to accumulate in late S and G2 when productive TLS is critical for cell survival.

277 ng of RNA polymerase to the promoter and the productive transcription complex formation.

278 omplexes in vitro and represses abortive and productive transcription initiation, as well as elongati

279 covered a molecular mechanism that increases productive transcription.

280 e TcdB glucosyltransferase domain and blocks productive translocation and delivery of the enzymatic c

281 ARs and microtubules that does not result in productive transport, but rather limits AMPAR availabili

282 re, and likely always have been, the primary productive units in human agricultural economies, sugges

283 nt to an antiviral protein and then evolve a productive use for that protein.

284 n becomes limited, causing a decrease in the productive use of absorbed light energy and likely a ris

285 For Hdac3(Delta/-) B cells that did show productive VDJ rearrangement, there was significant skew

286 seed rape (Brassica napus) is the third most productive vegetable oil crop on the global market; ther

287 ible loop of HIV-1 integrase is critical for productive viral DNA binding through specific contacts w

288 Productive viral infection often depends on the manipula

289 n PBMC's with TTSuV1 genomic DNA resulted in productive viral infection which was sustained for the t

290 Importantly, however, reactivation of productive viral replication (the lytic cycle) is necess

291 iptome to create an environment conducive to productive viral replication and egress.IMPORTANCE HPV g

292 Intriguingly, productive viral replication decreased phagocytosis of I

293 rom the infected to naive cell, resulting in productive viral replication in the naive cells.

294 vity, which can occur even in the absence of productive viral replication.

295 Superinfection of latently infected cells by productive virus could similarly remove those cells thro

296 lication and that its accumulation restricts productive virus growth.

297 ronment in virus-infected cells that permits productive virus infection.

298 ful birds during summer, when they used less productive waters, suggesting a link between breeding ou

299 nditions migrating further and visiting less-productive waters; this in turn led to differences in fl

300 tronically active components are arranged in productive ways.