ライフサイエンスコーパス: profiling

1 genitor cells, with global surface proteomic profiling.

2 range of full-lipidome quantitative shotgun profiling.

3 ysis approach complementary to human sensory profiling.

4 udies have used alternative methods for such profiling.

5 uid chromatography-mass spectrometry (LC-MS) profiling.

6 as hyper-spectral imaging, depth mapping, 3D profiling.

7 ctive for transcription factor and chromatin profiling.

8 n (XCI) confounds allele-specific epigenomic profiling.

9 zed histopathologically and through cytokine profiling.

10 y profiling and 16S sequencing for taxonomic profiling.

11 due resolution by in vivo selective ribosome profiling.

12 s, were purified and processed for proteomic profiling.

13 ld be improved by intragraft gene expression profiling.

14 termined by Lymph2Cx digital gene expression profiling.

15 neration can be revealed by genome-wide H3.3 profiling.

16 chromatin immunoprecipitation, and ribosome profiling.

17 have repeatedly revolutionized transcriptome profiling.

18 al disease biomarkers through transcriptomic profiling.

19 7 thereafter and subjected to lipid mediator profiling.

20 single-cell MAB-seq (scMAB-seq), capable of profiling 5fC and 5caC at genome scale using approximate

21 We conclude that plasma profiling after STEMI may help identify patients with a

22 Further transcript profiling among different cork oak tissues and condition

23 Depth-profiling analysis incorporating the electric field depe

24 We performed gene expression profiling analysis of 542 human acute myeloid leukemia (

25 Unsupervised gene expression profiling analysis, including principal component analys

26 agenomic sequencing for functional community profiling and 16S sequencing for taxonomic profiling.

27 leaf RN variation, parallel metabolite level profiling and assays of total protein and starch were pe

28 e further extended to problems in metagenome profiling and cell type inference.

29 ne metastasis, we conducted genome-wide mRNA profiling and DNA exon sequencing of two cell lines (TMD

30 lication of methods for widespread epigenome profiling and engineering may generate new avenues for u

31 Chemical profiling and gene expression studies showed that solana

32 Basal lineage-specific profiling and genetic loss-of-function experiments revea

33 Epigenomic profiling and genome editing revealed that AMIGO2 is reg

34 ectum using microarray based transcriptional profiling and identified several novel candidate retinot

35 Expression profiling and in vitro mechanistic studies showed that s

36 of CD8 T-cell activation, combining polysome profiling and microarray analysis.

37 Using a mitochondrial ribosome profiling and mitochondrial poly(A)-tail RNA sequencing

38 Advances in genome profiling and next-generation sequencing have led to the

39 t directly with CsrA in vivo, while ribosome profiling and RNA-seq uncover the impact of CsrA on tran

40 By combining these substrate profiling and structural data, we were able to design a

41 rferon expression in neurofibroma by protein profiling, and show that treatment of neurofibroma-beari

42 developed a population-level microsatellite profiling approach, SID (Saccharomyces cerevisiae IDenti

43 Single-cell transcriptional profiling at E9.5 reveals that endocrine-committed cells

44 to neonatal mice enabling longitudinal TFAR profiling by continued bioimaging throughout the lives o

45 mRNA profiling by microarray analysis revealed that the expre

46 messenger RNA was subjected to transcriptome profiling by microarray.

47 Expression profiling by RNA-sequencing revealed 77 genes with a pro

48 High throughput mRNA expression profiling can be used to characterize the response of ce

49 -seq) have been developed for simultaneously profiling chromatin accessibility and DNA methylation on

50 Body-wide functional profiling classified pathways into universal, human-enri

51 Activity profiling, complex isolation, and homology modeling data

52 Culture-independent bacterial community profiling confirmed that most isolates were representati

53 ic liver disease, but comprehensive cytokine profiling data across different clinical characteristics

54 integrating IG genotyping with functional Ab profiling data as a means to better predict and optimize

55 by integrating gene and microRNA expression profiling data from hearts of T. cruzi infected mice.

56 Large-scale molecular profiling data have offered extraordinary opportunities

57 Comprehensive genomic profiling data in this study provide insight into nivolu

58 dbDEMC 2.0 documents 209 expression profiling data sets across 36 cancer types and 73 subtyp

59 network-level constraints on transcriptional profiling data significantly improves interpretability.

60 lts were bolstered by global transcriptional profiling data that showed they were transcriptionally i

61 signal when applied to low-quality chromatin profiling datasets across individuals, cell types and sp

62 number of publicly available transcriptional profiling datasets.

63 Results of miRNA profiling demonstrated that miR-30a was markedly downreg

64 Subsequent metabolite profiling discovered that insufficient NADPH due to GLS2

65 By using dynamic proteome profiling (DPP), we investigated the contribution of bot

66 ularly useful for the NGS-based targeted STR profiling, e.g., in genetic and human identity testing.

67 Kinase profiling efforts revealed that 4-phenylquinolin-2(1H)-o

68 Depth profiling experiments conducted on SSA generated by a fr

69 ugh none has been cloned to date, transcript profiling experiments have identified candidate genes as

70 d shed light on A-site occupancy in ribosome profiling experiments more broadly.

71 Genetic studies and transcriptional profiling experiments show that this single protein is i

72 HSP70-1 was identified via expression profiling following IL-5 stimulation.

73 ne investigation of variability in taxonomic profiling for the Microbiome Quality Control (MBQC) proj

74 Also, the initial kinetic profiling for the nucleophilic substitution supports an

75 We now provide records profiling four prominent virology conferences over the y

76 , through morphology analysis, transcriptome profiling, functional perturbations and mathematical sim

77 ro differentiation models of human DCs, gene profiling, gene transduction, and immunohistology were u

78 Cancer genome profiling has revealed that specific events are more or

79 By profiling hundreds of synaptosomes, our data provide the

80 precipitation sequencing and gene expression profiling identified candidate ATOH1 targets in tumor ce

81 Whole genome mRNA expression profiling identified nicotinamide N-methyltransferase (N

82 Global gene expression profiling identified the transcription factor FoxO1 as a

83 We performed microRNA (miRNA) profiling in 318 serum samples from 69 liver transplant

84 pplying this antibody for protein expression profiling in 44 normal and 21 malignant human tissues, w

85 refore performed genome-wide DNA methylation profiling in a cohort of 39 patients.

86 Epigenetic profiling in diploid, allopolyploid, and domesticated co

87 Ribosome profiling in ER-stressed cells lacking these factors rev

88 ith Y-chromosome short tandem repeat (Y-STR) profiling in large-scale crime investigations.

89 vitro signaling assays and in vivo metabolic profiling in obese mice to investigate the effects of IG

90 may impact adversely on personalised insulin profiling in patients with diabetes.

91 We performed genome-wide gene expression profiling in peripheral blood leukocytes of adult patien

92 miRNA profiling in plasma samples from neonatal PA patients an

93 s impaired in H2A.Z deposition, and by H2A.Z profiling in stress conditions, we investigated the impa

94 miRNA profiling in the human brain has revealed miR-132 as one

95 Transcriptional profiling in the same animals identified 2342 genes with

96 ential of nanometer resolved elemental depth profiling in the soft X-ray range with a laboratory sour

97 Conclusion COO profiling in two prospective randomized DLBCL trials fai

98 We performed comparative ribosome profiling in yeast and mice with various ribonucleases i

99 induced genes identified in transcriptional profiling include those for putative enzymes and a carbo

100 We did comprehensive molecular profiling, including DNA methylation microarray analysis

101 Gene expression profiling indicated substantial down-regulation of insul

102 Gene expression profiling indicates that mouse tumors resemble human pro

103 al high-throughput sequencing techniques for profiling initiating ribosomes at single-nucleotide reso

104 Our multi-layer proteomics profiling, integrative network analysis, and functional

105 We introduce GEPIA (Gene Expression Profiling Interactive Analysis), a web-based tool to del

106 abundance in the skin, comprehensive skin FA profiling is needed.

107 ted for which extensive in vitro and in vivo profiling is reported.

108 trate through metabolomic and transcriptomic profiling marked suppression of glucocorticoid biosynthe

109 enomic and functional approaches such as BH3 profiling may allow us to prioritize novel-agent combina

110 the over-dispersion of RNA-Seq and ribosome profiling measurements separately, and performs a statis

111 A high-throughput single cell profiling method has been developed for matrix-enhanced-

112 throughput reduced representation expression profiling method that we term L1000.

113 ped a sensitive and accurate multiplex miRNA profiling method using modified isothermal EXPAR combine

114 verified by a targeted LC-MS based coumarin profiling method.

115 ide that are refining their image-based cell-profiling methodologies in pursuit of biological discove

116 le is to summarize the spectrum of molecular profiling methods available for investigating genomic as

117 r miRNA isolation, miRNA quantitation, miRNA profiling, miRNA target detection, and modulating miRNA

118 By profiling mRNA expression in the bone marrow mesenchymal

119 fication is a method initially developed for profiling mRNA from genetically defined cell types in co

120 Cellular bioenergetic profiling of 13 established and 12 patient derived ovari

121 We performed (epi)genomic profiling of 138 IMs from 148 cancer-free patients, recr

122 g cell subpopulations based on transcriptome profiling of 144 single LNCaP prostate cancer cells trea

123 whole-genome sequencing and gene expression profiling of 215 human induced pluripotent stem cell (iP

124 Gene expression profiling of 534 single ICM cells identified distinct do

125 Gene expression profiling of 84 oxidative stress and 249 inflammation-as

126 inciple, we conducted large-scale cell cycle profiling of 884 FDA-approved drugs.

127 We used the L1000 platform for large-scale profiling of 978 representative genes across thousands o

128 Here, we perform epigenomic enhancer profiling of a cohort of more than forty genetically div

129 Systematic profiling of a larger portion of circulating plasma prot

130 By focused profiling of a mechanistically relevant circulating T-ce

131 loped a novel assay that allows for parallel profiling of activity on all modified cytosines.

132 Using transcriptomic profiling of airway tissues, we sought to define the mol

133 Proteomic profiling of Akt signaling networks during Treg versus T

134 Ribosome profiling of an eIF5A-depleted strain reveals a global e

135 They perform, in real-time, tracking and profiling of behavior by using a supervised machine lear

136 Functional genomic profiling of BUB1B(R) versus BUB1B(S) isolates revealed

137 expression and suggests that transcriptomic profiling of bulk skin may inadequately capture the cont

138 Profiling of cardiomyocyte and nonmyocyte transcriptiona

139 Global gene expression profiling of Ccn6(fl/fl) mammary carcinomas and comparis

140 Transcriptional profiling of cDKO HSPCs revealed the activation of p53 a

141 y functionally annotated using morphological profiling of cDNA constructs, via a microscopy-based Cel

142 RNA-Seq is a powerful tool in transcriptomic profiling of cells and tissues.

143 novel image processing pipeline, for the 4D profiling of chemoconvulsant action in multiple brain re

144 Thus, proteomic profiling of cilia from diverse eukaryotes defines a con

145 Protein profiling of CTCs would complement the recent advances i

146 Transcriptional profiling of Ctip1 (-/-) embryonic skin identified alter

147 Here we used transcriptional profiling of dgca- structures to identify target genes f

148 nt circulation and that the quantitation and profiling of donor intra-exosomal cargoes may constitute

149 Transcriptome profiling of E2F-2-null, mature erythroblasts demonstrat

150 Comparative label-free LC-MS/MS profiling of EVs indicated that enhanced mineralisation

151 Systematic profiling of ex vivo (in yeast), in vitro, and in vivo a

152 Through comprehensive profiling of exomes and matched transcriptomes of >200 K

153 Growth phenotype profiling of genome-wide gene-deletion strains over stre

154 Molecular profiling of glioblastomas has revealed the presence of

155 Here, through transcriptomic and metabolomic profiling of hematopoietic cells, we reveal that EVI1 ov

156 Here, we performed epigenetic profiling of human resting naive, central and effector m

157 ications is demonstrated for the nontargeted profiling of human urine using a HILIC column.

158 use of the lack of techniques for multimodal profiling of individual cells.

159 Dynamic proteome profiling of individual proteins in human skeletal muscl

160 Lastly, we performed depth profiling of intact nodules to reveal the location of me

161 Microarray gene expression profiling of IVIg-generated pTreg revealed upregulation

162 Interestingly, transcriptome profiling of K14CreERT;DLX3(fl/fl) epidermis at 3 days i

163 ro translation systems, and in vivo ribosome profiling of liver tissue from mice carrying genomic del

164 Previous cardiac transcriptional profiling of LmnaH222P/H222P mouse, a small animal model

165 Our approach enables the selective profiling of mammalian proteomes in mixed biological env

166 technologies that enable highly multiplexed profiling of markers within a single cell promise to ove

167 tive breast cancer and support comprehensive profiling of metastases to inform clinical care.

168 brains were assessed for whole genome level profiling of methylome, transcriptome and miRNA using Ne

169 hput and robust quantitative methods for the profiling of micronutrients in human plasma, we introduc

170 Profiling of migrating cells revealed a possible SCF/c-K

171 LC/MS-compatible workflow allows for robust profiling of mitochondrial metabolites and serves as a s

172 ncreasingly being studied by high throughput profiling of molecular data over time.

173 udy, we performed genome-wide transcriptomic profiling of mouse whole blood during blood-stage infect

174 Proteomic profiling of mycolactone-exposed DCs showed that express

175 bust method for the comprehensive metabolite profiling of non-sterile rhizosphere soil, which represe

176 Ribosome profiling of NTT substitution R13P reveals heightened di

177 Using unbiased proteomic profiling of over 100 different cytokines, we found that

178 .6L, MYB59, and ANAC055, using transcriptome profiling of overexpressors and mutants, provided insigh

179 develop a new method for total transcriptome profiling of plasma-derived EVs by next generation seque

180 Through blinded profiling of postoperative plasma, we observe evidence o

181 external databases, including the PROSPECT (Profiling of Resistance patterns and Oncogenic Signaling

182 This study represents a comprehensive profiling of scarcely investigated low-abundance histone

183 and inside the infected region, and lateral profiling of sectioned nodules confirmed these molecular

184 Expression profiling of Setd1b(Gdf9) cKO MII oocytes revealed (1) t

185 Transcriptional profiling of skin and blood, however, revealed significa

186 cal research relies on the fast and accurate profiling of specific biomolecules and cells in a non-in

187 k aims at comparing ToF-SIMS molecular depth profiling of structured polymers (polystyrene (PS)-b-pol

188 on and post-translational modification (PTM) profiling of targeted protein in biofluid.

189 The complete profiling of the bio/nanomaterials interface and interac

190 ods for INTACT, T-DNA insertion mapping, and profiling of the complete nuclear transcriptome, includi

191 for high-throughput structural and molecular profiling of the diverse populations of synapses that co

192 technological advancements that enable broad profiling of the immune system to better understand the

193 Spatial profiling of the iron-laden infiltrates further demonstr

194 Transcriptional profiling of the nucleus accumbens (NAc) from handled ra

195 Profiling of the OFC synaptome identified alcohol-sensit

196 lving approach to therapy focuses on genomic profiling of the tumors to find molecular targets and de

197 Expression profiling of these genes during the course of ovule deve

198 High-throughput genomic and molecular profiling of tumors is emerging as an important clinical

199 This comparative whole-blood transcriptomics profiling of virulent and avirulent malaria shows the va

200 Untargeted profiling of volatile compounds shows that high quality

201 atory testing and discovery-based metabolite profiling of volume-restricted biospecimens.

202 ne concentrations, performed transcriptional profiling of whole blood and lesional morphea skin, and

203 Profiling of whole blood by CyTOF demonstrated profound

204 Microbiome profiling of wild-caught sand flies will be of great hel

205 Methods We performed digital gene expression profiling on a cohort of 245 formalin-fixed, paraffin-em

206 We performed microarray gene expression profiling on a large sample of resected lung tissues fro

207 quencing) for high-resolution open chromatin profiling on both native and formaldehyde-fixed cells.

208 ng embryogenesis, we performed transcriptome profiling on whole mouse embryos.

209 Metabolite and transcriptome profiling over a developmental time course of white spru

210 ments in islet (epi)genome and transcriptome profiling (particularly single cell analyses) are provid

211 assembly-based and mapping-based metagenomic profiling, particularly of high-complexity samples or en

212 DNA methylation profiling performed on cancer tissues prior to chemo/rad

213 Our approach, termed polymerase kinetic profiling (PKPro), involves monitoring XNA synthesis on

214 jectory of incorporation of global molecular profiling platforms into the routine clinical classifica

215 including differential expression analysis, profiling plotting, correlation analysis, patient surviv

216 Thus, ribosomal profiling provides valuable insights into translation in

217 Comparative proteome profiling regarding other cells demonstrated cell-type-s

218 However, its genomic profiling remains limited given its rarity.

219 Comparing our transcriptome profiling results to an earlier ribosome footprint analy

220 ome-wide occupancy mapping and transcriptome profiling reveal that nuclear TAZ/YAP promote SC prolife

221 erimental metastasis in vivo Gene expression profiling revealed a strong association between ER and C

222 Gene expression profiling revealed a subset of Forkhead box (Fox) genes

223 Gene expression and metabolite profiling revealed enhanced Pi starvation responses, suc

224 Transcriptomic profiling revealed high kisspeptin 1 (KISS1) related to

225 Gene expression profiling revealed primary and metastatic cells as two d

226 Our in-depth gene expression profiling revealed that 84% of genes are expressed in at

227 Transcriptional and epigenomic profiling revealed that IFE and HF tumor-initiating cell

228 This profiling revealed that loz1Delta cells accumulate highe

229 Cell-specific transcriptional profiling revealed that microglia selectively enhanced C

230 Metabolomic profiling revealed that MS-deficient Mtb cultured on fat

231 Intracellular metabolic profiling revealed that PknG is necessary for efficient

232 Genetic dissection and expression profiling revealed that this role is specifically mediat

233 Phosphoproteome profiling revealed the transcription factor FOXJ2 as a n

234 Community functional profiling revealed three distinct vaginal microbiome sub

235 Gene expression profiling reveals molecular similarities of mutant clone

236 ution mapping of m(6)A coupled with ribosome profiling reveals that m(6)A promotes the translation of

237 nnotation, RNA-protein interaction, ribosome profiling, RNA-seq analysis and RNA target prediction.

238 reading frames (ORFs) from regular ribosome profiling (rRibo-seq) data and outperform several establ

239 Herein, we used SHAPE-mutational profiling (SHAPE-MaP) to probe PAN in its nuclear, cytop

240 P = 0.006), and preliminary transcriptional profiling showed little evidence for IFN signature in wh

241 zyme assays and customized (13) C metabolite profiling showed that both targets are functionally impa

242 elease Using Nuclease (CUT&RUN), a chromatin profiling strategy in which antibody-targeted controlled

243 Brain gene expression profiling studies of suicide and depression using oligon

244 ession analyses and unbiased gene expression profiling studies offer a molecular explanation for the

245 silico analyses of HCC, utilizing published profiling studies showed an inverse correlation between

246 avorably to other large-scale perturbational profiling studies such as the connectivity map and libra

247 est herbicidal activities, and physiological profiling studies suggest that analogue 4 inhibits photo

248 Recent genome-wide ribosome profiling studies suggest that thousands of uORFs initia

249 s and used publicly available bladder cancer profiling studies to prioritize differentially expressed

250 is inactivated by looking at gene expression profiling studies.

251 Additionally, metabolic profiling suggested that both glycolysis and the tricarb

252 ect of hDBR1 on RNA splicing, and metabolite profiling supported the observation that neoplasm is tri

253 flow-nanospray mass spectrometry nontargeted profiling technique to identify changes in the exposome

254 he advent of high-throughput DNA methylation profiling techniques has enabled the possibility of accu

255 Unbiased, "nontargeted" metabolite profiling techniques hold considerable promise for bioma

256 Cell wall profiling techniques showed that the pretreatment led to

257 availability of genomic and other molecular profiling technologies provide an unprecedented opportun

258 )C-DnsHz labeling LC-MS is a useful tool for profiling the carbonyl submetabolome of complex samples

259 Profiling the expression patterns of snoRNAs is the init

260 m supported lipid bilayers (SLBs) as well as profiling the extent of deformation among adsorbed vesic

261 We show that the method is suitable for profiling the rhizosphere chemistry of Zea mays (maize)

262 By profiling the transcriptomes of individual cells, single

263 t technology for genome-wide transcriptional profiling, the vast majority of RNA-Seq studies typicall

264 e an invaluable tool for tumor tissue immune-profiling to allow multiple targets in the same tissue s

265 quantitative pathology, and gene expression profiling to analyze TLS formation in human lung squamou

266 enome-wide chromosomal copy number variation profiling to assess the presence of tumor DNA fractions

267 is also the first reported use of metabolite profiling to characterise the physiological impact of ly

268 Here we use exometabolomic profiling to examine the time-varying substrate depletio

269 will be how to use the results of molecular profiling to guide prognosis and selection of actionable

270 i-synthetic lethal screen and transcriptomic profiling to identify genes enabling BLM-deficient and/o

271 Therefore, we have used cellular expression profiling tools to define the distinct miRNA expression

272 , and low-cost alternative to sequencing for profiling transcriptomes.

273 sed susceptibility, we performed metabolomic profiling using high performance liquid chromatography t

274 We performed miRNA and mRNA profiling using high throughput stem-loop reverse-transc

275 We demonstrated single-cell metabolomic profiling using rat alveolar macrophage cells incubated

276 Transcriptional profiling using RNA sequencing (RNAseq) has emerged as a

277 We evaluated whole blood profiling using RNASeq to discriminate infectious agents

278 2 cycles) for epigenomic and transcriptomic profiling using the Infinium HumanMethylation450 BeadChi

279 Consistent with this, comparative metabolite profiling utilizing a number of A. thaliana relatives wi

280 escribe a procedure for metabolome-based BVC profiling via dynamic (i.e., continuous airflow) or stat

281 rgrowth syndromes, we employed tumor genetic profiling via high-depth next-generation sequencing usin

282 (1)H HR-MAS NMR metabolite profiling was achieved from a small sample of intact sau

283 Activity-based protein profiling was applied to pooled plasma samples to enrich

284 Biochemical profiling was conducted to confirm a CDG type I defect.

285 Meta-mass shift chemical (MeMSChem) profiling was developed to identify mass differences bet

286 miRNome expression profiling was performed in a mouse model of propionic ac

287 Mass spectrometry-based proteomic profiling was performed on early postnatal mouse corpus

288 Using isotopolog profiling we demonstrate that (13)C patterns of fungal F

289 otype microarrays and comparative metabolite profiling we demonstrate the impact of the well-characte

290 Through transcriptomic profiling, we determined that low expression of the ergo

291 Using BH3 profiling, we find that mitochondria of many adult somat

292 g whole-exome sequencing and transcriptional profiling, we found that the long non-coding RNA MIR100H

293 Using microarray-based gene expression profiling, we show that Ly6C(hi) iMOs isolated from the

294 By global proteomic and phosphoproteomic profiling, we show that, in BL, HSP90 inhibition comprom

295 de shRNA library screen and global proteomic profiling, we showed that JA targets the spliceosome by

296 ion, and comprehensive genomic and metabolic profiling were conducted.

297 r metabolic pathways, RNA-Seq and metabolite profiling were performed on stalks and leaves.

298 we term functionally-relevant morphological profiling with great potential to improve our understand

299 This enables artifact-free depth profiling with high sensitivity and low operational effo

300 we present dimethyl sulfate (DMS) mutational profiling with sequencing (DMS-MaPseq), which encodes DM