ライフサイエンスコーパス: progenitor B-cell

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1 Cre knockin animals to delete Hdac3 in early progenitor B cells.

2 ubiquitination in mature B cells, but not in progenitor B cells.

3 ine leukemia virus induces transformation of progenitor B cells.

4 terol depletion or overexpression of RGS1 in progenitor B cells.

5 nts may lead to neoplastic transformation of progenitor B cells.

6 atively, in the growth arrest of transformed progenitor B cells.

7 STAT5) activation occurs frequently in human progenitor B-cell acute lymphoblastic leukemia (B-ALL).

8 FAK)-VLA4 pathway plays an important role in progenitor B cell adhesion and migration.

9 istone H3 Lys27 trimethylation (H3K27me3) in progenitor B cells and B-ALLs, and 'bivalent' genes with

10 gion gene assembly in T lineage cells and in progenitor B cells and have also implicated 3'Ekappa as

11 bone marrow, RGS1 mRNA expression is low in progenitor B cells and high in mature B cells, implying

12 nation-activating gene-initiated IgH DSBs in progenitor B cells and that these dicentrics can be prop

13 and H3K4me3 at their promoters in wild-type progenitor B cells are preferentially overexpressed in t

14 biclonal lesions in which we determined the progenitor B cell by immunoglobulin heavy chain (IgH) ge

15 Interleukin 7-dependent progenitor B-cell clones and lines expressing B220 and C

16 Progenitor B cells deficient in Pax5 are developmentally

17 ses: (i) the Janus kinase/STAT5 pathway (ii) progenitor B-cell differentiation and (iii) the CDKN2A t

18 ects of pre-B cell development, causing most progenitor B cells expressing this H chain to be elimina

19 We report that after CXCL12 stimulation of progenitor B cells, focal adhesion kinase (FAK) and PI3K

20 of the Il7r locus at the earliest stages of progenitor B cell generation.

21 V(D)J recombination DSBs occur in developing progenitor B cells in the bone marrow, we sought to eluc

22 Accordingly, SOCS3 expression was low in progenitor B cells, increased in immature B cells, and h

23 Sustained adhesion of progenitor B cells is associated with prolonged FAK acti

24 and that the turnover rate of APE2-deficient progenitor B cells is nearly normal.

25 matic increase in the frequency of specified progenitor B-cells marked by expression of a lambda5 (Ig

26 Exactly how progenitor B cells perform the task of balancing prolife

27 5 (CCR5) expression and function of primary progenitor B-cell populations in human bone marrow.

28 by signaling through CCR5, could affect all progenitor B-cell populations through a novel mechanism

29 signal transduction events that control the progenitor B cell (pro-B cell) to precursor B cell (pre-

30 expression was more efficient in generating progenitor B cells (pro-B cells) compared with the more

31 Progenitor-B cells recombine their immunoglobulin (Ig) l

32 Progenitor B cells reside in complex bone marrow (BM) mi

33 profile analysis of interferon-beta-treated progenitor B cells revealed enhanced Daxx expression, wi

34 gous to human chromosome 21q22 confers mouse progenitor B cell self renewal in vitro, maturation defe

35 early B cell factor (EBF) are blocked at the progenitor B cell stage prior to immunoglobulin gene rea

36 deletion cooperated with E2A-PBX1 to expand progenitor B cell subpopulations, increasing penetrance

37 ation process called "rearrangement" forming progenitor B cells, then a Darwinian process of lineage

38 ferentiation, proliferation, and survival of progenitor B cells, this transcription factor may play a

39 We studied pre-pro-B cells and Rag(-/-) progenitor-B cells to determine whether Ig locus contrac

40 ic compartment resulted in a blockage of the progenitor B-cell-to-precursor B-cell development in bon

41 -deficient mice also succumb reproducibly to progenitor B cell tumors, demonstrating that Artemis is

42 of increased production of CD19+CD43+CD45R+ progenitor B cells upon the siRNA-mediated decrease in P

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