ライフサイエンスコーパス: prognostic

1 d BRAF-MMR status have also been found to be prognostic.

2 portunities for non-invasive diagnostics and prognostics.

3 gh more specific signatures have refined our prognostic abilities.

4 Subsequently the prognostic ability of these risk markers in coronary art

5 y was designed to define a dynamic composite prognostic ABMR score to predict kidney allograft surviv

6 bination with clinical data MRI has moderate prognostic accuracy in the evaluation of patients with P

7 nsfer information across diseases to improve prognostic accuracy.

8 This information might be useful as a prognostic aid for individual patients and as a surrogat

9 a significant expansion in our knowledge of prognostic and diagnostic biomarkers in many common infe

10 xt by providing a critical evaluation of the prognostic and diagnostic insights that this technology

11 rogen receptor alpha (ERalpha) is a critical prognostic and predictive biomarker in breast cancer.

12 In view of the heterogeneity in ARDS, both prognostic and predictive enrichment strategies are need

13 rpose Our previous work evaluated individual prognostic and predictive roles of TP53, KRAS, and EGFR

14 We aimed to assess the prognostic and predictive value of a 3q 19-gene signatur

15 ote metastatic dissemination, with potential prognostic and therapeutic implications for metastasis b

16 Overall, our results point to the prognostic and therapeutic value of identifying AGTR1 ov

17 fatal outcome, indicating a potential early prognostic and therapeutic window.

18 an uncommon entity that presents diagnostic, prognostic, and therapeutic dilemmas despite being a wel

19 ntial for enabling precision diagnostics and prognostics, as well as targeted patient recruitment of

20 hage infiltration in tumor tissue provides a prognostic assessment that is correlated with disease ou

21 , yet studies suggest an association between prognostic awareness and worse quality of life (QOL) and

22 goal was not "to cure my cancer." Conclusion Prognostic awareness is related to worse QOL and mood in

23 Interventions to improve patients' prognostic awareness should seek to cultivate more adapt

24 We sought to explore the relationships among prognostic awareness, coping, QOL, and mood in patients

25 e 180-day postdischarge mortality was 50%, a prognostic bench mark for hospice referral.

26 In conclusion, cancer-FOXP3 serves as a prognostic biomarker and a crucial determinant of immuno

27 vWF acts as a simple prognostic biomarker in AF and, whilst its addition to c

28 clin E (cytoplasmic)-negative) is a reliable prognostic biomarker in ER positive breast cancer patien

29 ated aortopathy is poorly understood, and no prognostic biomarker is currently available.

30 athobiology and proposed as a diagnostic and prognostic biomarker of idiopathic pulmonary fibrosis.

31 We hypothesized that the BSI can serve as a prognostic biomarker of overall survival (OS) and hemato

32 , but it also puts forward a potential novel prognostic biomarker to predict high-risk tumors before

33 If ultimately validated as a prognostic biomarker, urinary YKL-40 should be considere

34 important, albeit previously under-reported, prognostic biomarker.

35 is an easily available, observer-independent prognostic biomarker.

36 Prognostic biomarkers for the pancreatic neuroendocrine

37 argeting the pathways that involved in these prognostic biomarkers would be beneficial for the regres

38 out extracellular vesicles as diagnostic and prognostic biomarkers, as well as their potential applic

39 : NfL in plasma shows promise as a potential prognostic blood biomarker of disease onset and progress

40 s to quantify immune infiltration and assign prognostic categories to TNBCs.

41 is assay be interpreted using three separate prognostic categories: CTC-, CTC+/AR-V7-, and CTC+/AR-V7

42 independently associated with breast cancer prognostic characteristics and patient prognosis, most p

43 ccessful gene expression profile testing and prognostic classification.

44 We used the prognostic classifiers identified in a previously report

45 Artificial liver (UCLBAL) improved important prognostic clinical liver-related parameters, eg, a sign

46 lification without negative implications for prognostic, diagnostic, and therapeutic options for card

47 Results Prognostic discussion was not associated with a temporal

48 For TP53/KRAS mutation status, no prognostic effect was observed ( P = .61), whereas a bor

49 The prognostic end point was long-term mortality.

50 Purpose Standard cancer staging and prognostic estimates are determined at the time of the p

51 uvant treatment was an independent favorable prognostic factor (HR 0.76, 95% CI 0.58-0.99, P = 0.044)

52 Established IHD was an important prognostic factor across all HF types.

53 PRT was an independent prognostic factor associated with improved survival in s

54 mm was identified as an optimal cutoff for a prognostic factor for malignant disease in MD or mixed I

55 MRD, identified as a new prognostic factor for ML-DS patients, can be used for ri

56 evealed that elevated PDW was an independent prognostic factor for overall survival (hazard ratio, 2.

57 Response to rituximab induction remained a prognostic factor for overall survival despite treatment

58 ls in the surgical specimen, is an important prognostic factor for patients with pancreatic ductal ad

59 dissection group, were a strong, independent prognostic factor for recurrence (hazard ratio, 1.78; P=

60 currence of autoimmune disease is a negative prognostic factor for survival.

61 Tumor size is a prognostic factor for the majority of solid cancers, but

62 ibed that DDIT4 expression is an independent prognostic factor for tripe negative breast cancer resis

63 se to induction chemotherapy is an important prognostic factor in B-lymphoblastic leukemia (B-ALL).

64 analysis showed that MPV was an independent prognostic factor in CRC (HR = 1.452, 95% CI = 1.118-1.8

65 raventricular hemorrhage (IVH) is a negative prognostic factor in intracerebral hemorrhage (ICH) and

66 umor was the major inferior disease-specific prognostic factor in physical scores ( P < .01), whereas

67 es accounting for standard clinicopathologic prognostic factors (10-year biochemical recurrence-free

68 liver metastases (yes vs no), and number of prognostic factors (none vs one, two, or three).

69 c regression models, adjusting for important prognostic factors and clustering effects.

70 ct of these SNPs is independent of classical prognostic factors and there is no heterogeneity between

71 Prognostic factors are lacking in neurosarcoidosis (NS),

72 Long-term survival data are lacking, and prognostic factors are not well defined.

73 onal studies almost always have bias because prognostic factors are unequally distributed between pat

74 cohol on long-term survival and (2) identify prognostic factors at admission capable of predicting ab

75 udy of ambulatory DCM patients, we show that prognostic factors for all-cause DCM also predict outcom

76 l thickness and obstruction were significant prognostic factors for cardiovascular death.

77 o CCC pathogenesis and the identification of prognostic factors for CCC progression.

78 bMTV and refractory disease were independent prognostic factors for EFS.

79 Identification of prognostic factors for patients with relapsed/refractory

80 studies to assess pooled survival rates and prognostic factors for survival in patients with HCM.

81 and KIT mutation (exon 11) were significant prognostic factors for the probability of surviving beyo

82 h poor outcome independently of well-defined prognostic factors in neuroblastoma, breast cancer, DLBC

83 (LAVI) have been recently proposed as novel prognostic factors in several cardiovascular diseases.

84 fluence DDFI or OS after adjusting for known prognostic factors in young breast cancer patients.

85 Significant prognostic factors included the original 4 factors used

86 eplace the balance of both known and unknown prognostic factors offered by randomization.

87 , both SNTI and BMM are independent negative prognostic factors regarding DFS and OS, and the occurre

88 This study reanalyses pathological prognostic factors related to IBTR using long-term follo

89 PET/CT results and SUVs were compared with prognostic factors such as histologic grade (G1, G2, or

90 iomedical literature and synthesize data for prognostic factors that predict long-term mortality in p

91 asingly are used in addition to conventional prognostic factors to guide adjuvant chemotherapy (CT) d

92 signed drug and dosing regimen, and baseline prognostic factors were requested from the leaders of th

93 Propensity methods can deal with multiple prognostic factors, even if there are relatively few pat

94 presence of excessive blasts and other poor prognostic factors, hypomethylating agents are the prefe

95 cancer, most of whom were elderly, had poor prognostic factors, or had serious comorbidities.

96 nt extrahepatic disease (EHD), and to define prognostic factors.

97 invasion and lymph node metastasis are poor prognostic factors.

98 Disease (P < 0.0001) scores were independent prognostic factors.

99 res of PDACs with dMMR or MSI might serve as prognostic factors.

100 tional hazards models adjusting for baseline prognostic factors.

101 s was used to match patients for seven known prognostic factors.

102 backbone groups on the basis of established prognostic factors: PRETEXT I/II, PRETEXT III, PRETEXT I

103 revealed that bacteria associated with poor prognostic features were not responsible for the modific

104 The presence of these mutations in glioma is prognostic for better clinical outcomes with longer pati

105 Intriguingly, NSD1/2 mutations are not prognostic for nonlaryngeal SCCHN.

106 ne severities and features of initial DR are prognostic for PDR development.

107 including intraretinal cells that are highly prognostic for progression, can be followed and quantifi

108 RD) and microsatellite instability (MSI) are prognostic for survival in many cancers and for resistan

109 bute to improving the accurate assessment of prognostic groups in patients with GBM treated with radi

110 ed out a comprehensive motif analysis on the prognostic GSs from five cancer types.

111 om digital pathology datasets to investigate prognostic image biomarkers and genotype-phenotype assoc

112 derlying adjustment as a way of dealing with prognostic imbalance and to the basic principles and rel

113 Purpose To explore the prognostic impact and interdependence of the cell-of-ori

114 TP53 mutations (HR, 6.2; P < .0001) retained prognostic impact for overall survival (OS), whereas TP5

115 We assessed the characteristics and prognostic impact of 598 patients with CP-CML treated on

116 Conclusion We demonstrate the prognostic impact of CD62L shedding from T cells and inc

117 The aim of the study was to determine the prognostic impact of co-existence of APC and PIK3CA muta

118 and Cox regression were used to evaluate the prognostic impact of PDW.

119 igh-risk (HR, 2.6; P = .003) had independent prognostic impact on time to relapse.

120 me entity or have a different prevalence and prognostic impact remains unclear.

121 ndary MR during exercise, its functional and prognostic impact, and the way current treatment options

122 ssed frequency, cytogenetic characteristics, prognostic impact, and underlying biological origin of m

123 Their respective prognostic impacts on outcome prediction were compared u

124 oles in diagnosing diastolic dysfunction; 3) prognostic implications of abnormalities in E/A and E/e'

125 oth parameters have important diagnostic and prognostic implications, they should be interpreted in t

126 h epithelial ovarian cancer (EOC), but their prognostic importance and optimal cutoffs are still need

127 Our objective was to evaluate the prognostic importance of clinical and hemodynamic variab

128 The prognostic importance of hemodynamic values achieved aft

129 These results support the prognostic importance of treating intrahepatic HCC even

130 of the causative organism has a substantial prognostic importance.

131 eservation-related factors may be of greater prognostic importance.

132 4 expression was associated with an improved prognostic in gastric cancer.

133 BP1) and the Acute Liver Failure Study Group prognostic index (early, 0.686 alone, 0.766 with FABP1;

134 The MALT-lymphoma International Prognostic Index (MALT-IPI) also significantly discrimin

135 g, male v female, age-adjusted International Prognostic Index 0 or 1 v 2 or 3, age younger than 70 v

136 stablished cell of origin, the International Prognostic Index comprising clinical variables, and dual

137 patients into 3 risk groups according to the prognostic index developed from the final model.

138 arameter estimates from an adjusted model, a prognostic index for prediction of noncancer death was g

139 atified by Follicular Lymphoma International Prognostic Index risk group and geographic region.

140 ender, and Follicular Lymphoma International Prognostic Index score (0-2 vs 3-5).

141 The prognostic index that incorporated these measures with t

142 A prognostic index was built by Cox regression (stepwise s

143 The prognostic index yielded a c value of 0.747 for the pred

144 center study developed and validated a novel prognostic index, Risk Estimation of Tumor Recurrence Af

145 ors were included in the updated Lung-molGPA prognostic index.

146 The CAC score was also a prognostic indicator of CHD and ASCVD after controlling

147 Genetic etiology can be a prognostic indicator of disease severity and can influen

148 nts with lower motor neuron signs might be a prognostic indicator of milder phenotypes of disease.

149 to examine the feasibility of MPV value as a prognostic indicator of RCC.

150 (MetS) or diabetes identifies CHD and ASCVD prognostic indicators during a long follow-up period.

151 malignant progression and identification of prognostic indicators of aggressiveness.

152 rs, bleeding, and high viral loads were poor prognostic indicators of children with EVD.

153 tracapillary hypercellularity as novel, poor prognostic indicators of time from DKD to ESRD.

154 vival and to compare this to other potential prognostic indicators.

155 rved between lead or bone turnover and other prognostic indicators.

156 -associated macrophages (TAM), can be strong prognostic indicators.

157 There are no widely accepted prognostic indices for extranodal marginal zone lymphoma

158 Comparison of prognostic indices.

159 ic angiography provided significantly better prognostic information compared with FT and CAC testing

160 nferior myocardial wall provided incremental prognostic information for VT/VF over clinical and echoc

161 images for their incremental diagnostic and prognostic information in patients with nonischemic dila

162 re using the panel of nine proteins provided prognostic information independent of the REVEAL equatio

163 Our approach integrates the prognostic information of CMR imaging into a simple risk

164 underlying frailty may provide complementary prognostic information on long-term outcomes.

165 , all HRs with 95% CIs were pooled to obtain prognostic information on the location of the primary tu

166 with sodium did not add clinically relevant prognostic information on top of other well-established

167 lar tachyarrhythmias and provide incremental prognostic information over clinical and conventional ec

168 in the inferior region provided incremental prognostic information over clinical and echocardiograph

169 ix main categories of surrogate responses to prognostic information were identified: (1) receptivity,

170 d with a CZT SPECT camera provides excellent prognostic information, with low event rates in patients

171 lonal plasma cells while providing important prognostic information.

172 present in diagnostic testing that allow for prognostic insight and present algorithms for both diagn

173 us suppressor of SK1 signaling and potential prognostic marker and demonstrate the therapeutic potent

174 Our results suggest that Cdc6 is a potential prognostic marker and therapeutic target in breast cance

175 After multiple testing corrections, only 1 prognostic marker contributed a significant split point

176 cer cell proliferation, which may serve as a prognostic marker for lung cancer patients.

177 abundance in primary tumor might serve as a prognostic marker for metastatic potential.

178 RNA that has been originally identified as a prognostic marker for non-small cell lung cancer, in cer

179 at WIF1 methylation may serve as a potential prognostic marker for patients with CS.

180 y mutations as candidates for diagnostic and prognostic markers, and suggests new mechanisms for tumo

181 sk patients and to select the most important prognostic markers.

182 tumors, and evaluated their significance as prognostic markers.

183 lyzed the clinicopathologic correlations and prognostic meaning of different patterns of bone marrow

184 Our prognostic model can be extended to investigate the kine

185 A prognostic model comprising these genetic alterations ou

186 CT scoring systems contribute to a clinical prognostic model.

187 onalize molecular testing for predictive and prognostic molecular biomarkers involve selection of ass

188 n of breast cancer and the use of predictive/prognostic molecular signatures for guiding treatment de

189 artite Motif 14 (TRIM14) as a component of a prognostic multigene expression signature for NSCLC.

190 Diagnostic factors found to be most prognostic on initial analysis were PRETreatment EXTent

191 ecific CD8(+) TILs could skew the results of prognostic or diagnostic TIL assays.

192 215 cases (35%) but did not show significant prognostic or predictive effects.

193 colon cancer (CC) still does not represent a prognostic parameter when deciding for adjuvant or palli

194 first meta-analysis on this issue, comparing prognostic parameters in surgically treated, node-positi

195 rmline susceptibility variants displayed low prognostic performance consistently across cancer types.

196 ated BCLC nomogram were used to evaluate the prognostic performance of integrating primary anti-cance

197 The prognostic performance of prepT-stage and prepN-stage wa

198 Independent validation of the prediction and prognostic performance of the models was carried out on

199 ) analyses were performed for diagnostic and prognostic performances.

200 g the origin and differential diagnostic and prognostic potential of the putative marker of microglia

201 imaging biomarkers for their diagnostic and prognostic power in future prostate cancer clinical tria

202 This study validates the prognostic power of RETREAT, which may help standardize

203 er-related non-SMGs as predictors for cancer prognostic prediction and provide more supplemental cand

204 tation significantly (p < 0.05) improved the prognostic prediction in LGG patients.

205 Additionally, we constructed a prognostic prediction model that effectively predicted p

206 stratification of patients into appropriate prognostic/predictive subgroups.

207 present the 97-gene signature as an accurate prognostic predictor of overall survival and chemorespon

208 tential value of chromosome instability as a prognostic predictor.

209 However, the prognostic relevance of remnant liver ischemia (RLI) aft

210 hermore, histopathologic findings may retain prognostic relevance when a genetic diagnosis is establi

211 Moreover, FOXP1-SHQ1 deletion has prognostic relevance, with cancer recurrence associated

212 y microvascular impairment carries important prognostic relevance.

213 opean Leukemia Net (ELN) 2010 intermediate I prognostic risk AML (EFS, 26% +/- 4 vs 40% +/- 5 at 4 ye

214 A prognostic risk stratification model based on preselecte

215 and social health might further clarify the prognostic role of aging.

216 The prognostic role of cardiac magnetic resonance (CMR) and

217 We aimed to investigate the prognostic role of host antitumour immunity as represent

218 We investigated the functional and prognostic role of TRIM14 in NSCLC using in vitro and in

219 However, the prognostic roles of each individual S100, especially the

220 ogy where rearrangements play diagnostic and prognostic roles.

221 rimination index was improved with the MEGNA prognostic score (0.21; 95% CI, 0.11-0.33) compared with

222 The ABMR prognostic score could be used to inform therapeutic dec

223 The ABMR prognostic score derived from the prediction model ident

224 Prognostic score development: A total of 4,352 children

225 develop and externally validate a simplified prognostic score for ICC and to determine perioperative

226 The performance of the ABMR prognostic score was validated in an independent cohort

227 c dimension is incremental to well-validated prognostic scores in pulmonary arterial hypertension.

228 cored according to the revised International Prognostic Scoring System (IPSS-R) and presence of comor

229 with overt PMF were in higher International Prognostic Scoring System risk categories at diagnosis,

230 tic leukemia, according to the International Prognostic Scoring System, were randomly assigned using

231 The prognostic separation/discrimination index was improved

232 4.5 and NLR with cutoff 5.25 had independent prognostic significance for OS, while combined RDW and N

233 is well established, but its pathogenic and prognostic significance in HF with midrange (HFmrEF; EF

234 Purpose To determine the prognostic significance of blasts, and of white and red

235 The prognostic significance of CD8A, GLUT1, and COX5B gene e

236 Additional studies are required to test the prognostic significance of CNA presence in disease relap

237 To examine the prognostic significance of CRP in ALS.

238 We determined the prognostic significance of dIVH in the Intensive Blood P

239 Prognostic significance of each protein was examined by

240 Conclusion Our study supports the strong prognostic significance of early NPM1m PB-MRD, independe

241 duration of adjuvant imatinib influences the prognostic significance of KIT proto-oncogene receptor t

242 The prognostic significance of nonsustained ventricular tach

243 e in determining the underlying etiology and prognostic significance of VT.

244 Analyses were adjusted for the prognostic stage, size, grade, and necrosis (SSIGN) scor

245 during index hospitalization provides better prognostic stratification of ST-segment-elevation myocar

246 In contrast, prognostic strength of prepN-stage was better than cN-st

247 Prognostic strength of prepT-stage was similar to clinic

248 ed to develop a risk score model to stratify prognostic subgroups among 106 patients developing postt

249 e randomized DLBCL trials failed to identify prognostic subgroups, whereas dual expression of MYC and

250 Purpose To develop a prognostic system for transplantation-age patients with

251 eptides have led the way as a diagnostic and prognostic tool for the diagnosis and management of hear

252 and monitor antitumor immune responses as a prognostic tool to predict patient responses to checkpoi

253 The aim of this study was to validate their prognostic use and reproducibility across a multicenter

254 cardiovascular mortality and (2) incremental prognostic use of indexing aortic root to patient height

255 do AVR, baseline LV-GLS provides incremental prognostic use over established predictors and could pot

256 etermine whether LV-GLS provides incremental prognostic use.

257 chanical computational models have potential prognostic utility in patients after an acute ST-segment

258 Our study objective was to evaluate the prognostic utility of a modified HEART score (m-HS) with

259 dies have yielded conflicting results on its prognostic value after targeted temperature management.

260 in blood and CSF were recently shown to have prognostic value for clinical HD progression and brain a

261 inflammatory response that shows significant prognostic value for several diseases.

262 importantly, BRCA score provides significant prognostic value in both breast and ovarian cancers afte

263 e quantified diaschisis and investigated its prognostic value in glioma.

264 nd downstream targets have a strong negative prognostic value in lung adenocarcinoma.

265 core that correlates with aneuploidy and has prognostic value in many types of cancer), only CA20 was

266 t chemoradiotherapy (nCRT) and to assess its prognostic value in patients with esophageal cancer.

267 iary lymphoid structures and abrogates their prognostic value in patients with lung cancer.

268 volved in the aggressiveness of PTC, but its prognostic value in PTC-related mortality remains to be

269 tion at the time of amniocentesis may have a prognostic value in terms of congenital infection and ne

270 in congenital hCMV infection (cCMV), but its prognostic value is unknown.

271 Purpose To evaluate the prognostic value of a simple index of left ventricular (

272 lymphoma, as a model of diffuse disease, the prognostic value of baseline total metabolic tumor volum

273 increasing body of literature to support the prognostic value of cardiac magnetic resonance imaging w

274 We explored the prognostic value of cardiac markers (troponins I and T,

275 trate that MRD-negative status surpasses the prognostic value of CR achievement for PFS and OS across

276 aterone or enzalutamide and investigated the prognostic value of CTC detection (+ v -) and AR-V7 dete

277 We characterized the prognostic value of histologic findings in DKD for time

278 The prognostic value of margin group status was confirmed on

279 aim of the current study was to evaluate the prognostic value of MPI performed with a CZT SPECT camer

280 The prognostic value of MRI biomarkers was assessed by retro

281 ivariate analysis were used to determine the prognostic value of NLR, PLR and PC for overall and canc

282 The prognostic value of the new management algorithm that in

283 These results consolidate the prognostic value of the NLR, PLR, LMR and GPS/mGPS in pa

284 The aim of this study was to investigate the prognostic value of the quantitative assessment of skele

285 The clinical impact and prognostic value of this classification has been confirm

286 ue characterization in this setting, but the prognostic value of this method as a primary assessment

287 The prognostic value of this simple measurement needs to be

288 We conducted a meta-analysis to assess the prognostic value of thyroid hormones in AIS.

289 The prognostic value of TMTV remained quite similar whatever

290 a simple risk score that showed incremental prognostic value over clinical risk factors in ST-segmen

291 res best predict outcome and what additional prognostic value the CT scoring systems contribute to a

292 This prognostic value was independent of the patient's age at

293 ng classification and grading approach is of prognostic value, it harbours shortcomings such as ill-d

294 ncies in which TILs were not known to have a prognostic value.

295 suggesting that the pre-tumor epigenome has prognostic value.

296 edema after pulmonary endarterectomy and had prognostic value.

297 In conclusion, FER rs4957796 might act as a prognostic variable for survival in patients with severe

298 information on top of other well-established prognostic variables.

299 le and before and after adjustment for other prognostic variables.

300 ence, pretreatment imaging features were not prognostic, while texture-strength measured at the end o