ライフサイエンスコーパス: program of

1 erweight and obese women after a weight-loss program of 12 wk.

2 een implemented in the national immunization programs of 79 countries, including 36 low-income countr

3 s allow mammals to alter the transcriptional program of a cell in response to environmental cues.

4 ve defined the phenotype and transcriptional program of a subset of antigen-specific B cells, which w

5 ence and kinetics can be rewired through the programming of a sequence motif of the general form G-G/

6 onscious representations encompass the motor programming of actions that could be accomplished congru

7 A program of adapted physical activity (APA) is recommende

8 f dynamin-1 in cancer cells contributes to a program of "adaptive" CME that alters signaling to enhan

9 maturity in the Preterm Birth and Early Life Programming of Adult Health and Disease (ESTER) Study, a

10 nd place it as a critical regulator of fetal programming of adult metabolic disease.

11 homeostasis and regeneration are mediated by programs of adult stem cell renewal and differentiation.

12 ally isolated and manipulated the cell cycle programs of adult stem cells and enterocytes.

13 underlying fetal growth restriction and the programming of adverse health outcomes in the adult.

14 Our data suggest that developmental programming of aging importantly contributes to (and per

15 d for the multiple agencies behind its wider program of agropastoral colonization.

16 vaccine (IPV) into the routine immunization programs of all countries using oral polio vaccine (OPV)

17 mplicity of the t2M/t4M binding site enables programming of allostery in RNAs, recoding oligo-U domai

18 rns a complex posttranscriptional regulatory program of alpha-1-antitrypsin expression.

19 RNA-binding proteins PTBP1 and PTBP2 control programs of alternative splicing during neuronal develop

20 and antidepressant responses via epigenetic programming of an xCT-mGlu2 network.

21 it directly activates a core transcriptional program of approximately 100 genes with diverse biologic

22 ed useful SNP markers for selective breeding programs of Asian seabass.

23 with B cell fate as well as the maintenance program of B cells, leading to changes in B cell immune

24 ue to an altered development and maintenance program of B cells.

25 vel function of Id1 in BAT thermogenesis and programming of beige adipocytes in white adipose tissue

26 may partly arise from altered developmental programming of beta-cells.

27 nt for excellence in practice evolved into a program of board certification through the creation of w

28 data provide key insights into the metabolic programming of border cells that strongly implicate a mo

29 tempt to accelerate genetic gain in breeding programs of both animals and plants.

30 ine that proved to be pivotal in shaping the programs of both lymphocyte subsets.

31 ne the role of the fetal PT in developmental programming of brain function by maternal melatonin and

32 To identify kidney-specific and shared programs of branching morphogenesis, comparative express

33 ial lipid metabolism and the differentiation program of breast cancer cells, thereby revealing a prev

34 ation of their diagnostic value; and (iii) a program of broad exploration followed by increasingly ri

35 xCTSes play key roles in the transcriptional program of cancer and germ cells.

36 val signaling is critical for the metastatic program of cancer cells.

37 to total Google search volume, and National Program of Cancer Registries recorded cancer incidence a

38 o 2013, at the state level, per the National Program of Cancer Registries.

39 cells, where entry is mediated by a variable program of capsid dynamics, ultimately leading to genome

40 ating cardiovascular aging and developmental programming of cardiovascular disease, and aging being d

41 ating cardiovascular aging and developmental programming of cardiovascular disease.

42 contributions of each of these stressors to programming of cardiovascular dysfunction.

43 lutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses to vir

44 that the LTbetaR/IFN-I axis is essential for programming of CD8(+) T cells to mediate immunopathology

45 identify a role for 1,25D3 in the molecular programming of CD8(+) T-cell conversion to an IL-13-secr

46 esis that unfolds according to a predictable program of cell division.

47 s are disrupted, RIPK1 is free to unveil its program of cellular demise.

48 form studies of aging and enable the precise programming of cellular age in parallel to cell-fate spe

49 develop engineering-driven approaches to the programming of cellular functions that could yield trans

50 After inducing a transcriptional program of centriole biogenesis, E2f4 forms apical cytop

51 National Basic Research Program of China (973 Program).

52 National Basic Research Program of China, National Key Technology R&D Program.

53 Top-Notch Young Talents Program of China, Special Support Program of Guangdong,

54 not amenable to selective ERRgamma-directed programming of classic exercise-like effects in the skel

55 To circumvent these problems, a program of clinical standardization was embedded in the

56 We suggest that the similar ontogenetic programs of closely related populations constrain growth

57 nvironmental stimuli on mechanisms governing programs of CNS myelination under normal and pathologica

58 modifiable targets to prevent developmental programming of common diseases.

59 challenges but are also poised to execute a program of compositional and conformational changes to f

60 ensity of foods, paired with a comprehensive program of consumer education, can become the foundation

61 ) integrates collagen secretion into broader programs of craniofacial bone formation.

62 of attachment, ATF4 activated a coordinated program of cytoprotective autophagy and antioxidant resp

63 expressed coincident with the timing of sex programming of developing oocytes by methyl farnesoate i

64 d during the implementation of an integrated program of diagnosis and treatment of febrile illness in

65 ation enzymes and remodels the translational program of differentiating cells in favour of neural cre

66 XRs) are key elements of the transcriptional program of differentiating osteoclasts.

67 The program of differentiation is determined, in part, by FO

68 local cytokine triggers, undergo a secondary program of differentiation that leads to the loss of CXC

69 f gene transfer agents, (ii) facilitation of programs of differentiation such as those that allow spo

70 Programs of drug discovery generally exploit one enantio

71 The results thus reveal a highly conserved program of dynamic microexon regulation associated with

72 uggested to play a role in the developmental programming of dysmetabolism based on studies of human s

73 and AR strongly enhance the transcriptional program of each other, whereas FOXA1 regulates GATA2- an

74 -ecdysis while directly expressing the motor program of ecdysis.

75 -specific CD8(+) T cells, we reveal a common program of effector differentiation that is regulated by

76 er reprogramming activates a transcriptional program of embryonic foregut endoderm.

77 initiating cells can co-opt the self-renewal program of endogenous stem cells as a means of enforcing

78 itors do not execute the adult morphogenesis program of enlargement, polyploidization, and proplatele

79 us, associated with execution of the genetic program of epidermal barrier formation, to a fully inact

80 Global demethylation is part of a conserved program of epigenetic reprogramming to naive pluripotenc

81 Skin wound repair requires a coordinated program of epithelial cell proliferation and differentia

82 transcriptional pathway to silence a genetic program of epithelial homeostasis in breast cancer stem-

83 ram in epidermis, which revealed large-scale programs of epithelial cell-type-specific splicing requi

84 to coordinate endocrine differentiation with programs of epithelial growth, maturation, and morphogen

85 cells, as demonstrated by the selection for programs of epithelial-to-mesenchymal transition (EMT) d

86 - and development-associated gene expression program of ESCs.

87 Preferential epigenetic programming of estrogen response after in utero xenoestr

88 selectively altered the normal developmental programming of estrogen-responsive genes via modificatio

89 ced these cells in vivo, indicating abnormal programming of Fas-deficient T cells before the DNT stag

90 scriptional coactivator that regulates broad programs of fatty acid consumption, to identify 3-hydrox

91 Here, we define the largest program of functionally coordinated, neural-regulated AS

92 The metabolic programs of functionally distinct T cell subsets are tai

93 tients in 23 cancer types using two reliable programs of FusionScan and TopHat-Fusion.

94 er PKA is sufficient to initiate the complex program of GC responses to FSH.

95 In this way, temporal programming of gelation was possible under mild conditio

96 nto how HSV-1 causes changes in the cellular program of gene expression and how the virus coopts host

97 An intrinsic program of gene expression determines the critical perio

98 ted Tfh cell differentiation through a broad program of gene expression exemplified by its negative r

99 Furthermore, a keratinocyte ERbeta-dependent program of gene expression is subverted in SCCs from var

100 y analyses revealed that RSK1 orchestrated a program of gene expression that promoted cell motility a

101 This control is achieved through a complex program of gene expression.

102 offspring behavior by disrupting epigenetic programming of gene expression in the brain.

103 Skin development is governed by complex programs of gene activation and silencing, including mic

104 tional network specifying microglia-specific programs of gene expression and facilitate efforts to un

105 Programs of gene expression are executed by a battery of

106 How SMAD2 activates programs of gene expression that are modulated over time

107 areas to repress motor and activate sensory programs of gene expression, enabling establishment of s

108 unequal sized daughter cells with dissimilar programs of gene expression.

109 in most organisms requires tightly regulated programs of gene expression.

110 n antagonistic proliferative and contractile programs of gene expression.

111 Transcription factors (TFs) regulate complex programs of gene transcription by binding to short DNA s

112 MYC activates a stereotypic transcriptional program of genes involved in cell growth in mammary epit

113 totic cell cycle machinery components by the program of germ cell development.

114 critical role in the formation and metabolic programming of glycolytic myofibers in skeletal muscle.

115 ng Talents Program of China, Special Support Program of Guangdong, Specialized Research Fund for the

116 or Ssbp2 in the function and transcriptional program of hematopoietic stem and progenitor cells (HSPC

117 asis and regeneration, yet the developmental program of hepatic vessel formation and the embryonic or

118 ong-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in

119 ects offspring from WD-induced developmental programming of hepatic lipotoxicity and may help slow th

120 , Specialized Research Fund for the Doctoral Program of Higher Education (20110171120099), Program fo

121 Mechanisms to coordinate programs of highly transcribed genes required for cellul

122 tic islet formation, as well as to life-long programming of hormonal determinants of glucose homeosta

123 We show that the transcriptional program of hPGCs is distinct from that in mice, with co-

124 duced steroids acutely to PNS rats overrides programming of hyperactive HPA axis responses to immune

125 he PVH appears to be required for early-life programming of hypertension arising from either maternal

126 (Comparison of Empiric to Physician-Tailored Programming of ICDs [EMPIRIC], Multicenter Automatic Def

127 In this Review we discuss the developmental program of ILCs and transcription factors that guide ILC

128 parenchyma and SCS in what we speculate is a program of immune surveillance that helps achieve LN bar

129 The programming of implantable cardioverter-defibrillators (

130 cal trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (

131 lture recapitulate progressive developmental programs of in vivo progenitor and postmitotic different

132 implants are important both for guiding the programing of individual users' implants and for the eva

133 To study and compare transcriptional programs of induced cells versus primary DA neurons is a

134 Therefore, a mass EV-A71 vaccination program of infants and young children should provide sig

135 ounterparts, and this has stimulated several programs of inhibitor discovery with a view to targeting

136 ethnically diverse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRIS

137 Remarkably, somatic genetic re-programming of intracellular clocks in SCN astrocytes wa

138 We propose a program of investigation that would take this forward in

139 e fetal kidney, effects that likely underpin programming of kidney development and function by a mate

140 ossible mechanism for maintaining epigenetic programming of large-scale chromatin domains throughout

141 d the intermediates in the lead optimization program of linagliptin, the onset of slow binding kineti

142 At this time, a coordinated program of lineage diversification, cell-fate specificat

143 to identify the core transcriptional control program of lineage specification.

144 hese results illuminate a previously unknown program of liver regeneration after acute injury and all

145 important in current psychosocial screening programs of living organ donors.

146 It allows programming of lytic phages to kill only antibiotic-resi

147 Rather than reinforcing a specific program of macrophage polarization, Rev-erbs repress sub

148 one marrow (BM) stem/progenitor cells in the programming of macrophages toward a proinflammatory phen

149 entiation under control of the developmental program of male gametogenesis, function to direct cell t

150 n contrast to the pronounced proinflammatory program of mature DCs, tolerogenic DCs displayed a marke

151 become pigmented and enact a gene expression program of melanocyte differentiation.

152 ules may not represent a specific biological program of messenger ribonucleoprotein (mRNP) assembly,

153 eIF3 binds to a highly specific program of messenger RNAs involved in cell growth contro

154 p9x, and has major impact on the tumorigenic program of metastatic melanoma.

155 acterial taxa whose representations define a program of microbiota assembly and maturation during the

156 otential of alpha7nAChR agonists in early re-programming of microglia in neonates exposed to in utero

157 lpha (HIF1alpha) mediated this functional re-programming of monocytes, revealing a potential mechanis

158 ginate from pericycle cells, which undergo a program of morphogenesis to generate a new lateral root

159 k that forms in the embryo by a post-mitotic program of morphogenesis.

160 e found that p53 controls specific and broad programs of mTEC differentiation.

161 his transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restr

162 gain deeper insight into the gene expression program of murine HSCs, we combined single-cell function

163 While an innate program of myelin development proceeds independently of

164 United Kingdom, funded Communities First, a program of neighborhood regeneration delivered to the 10

165 an in vivo - in vitro model of developmental programming of neuroinflammation induced by lipopolysacc

166 We show that PTBP1 controls a program of neuronal gene expression that includes the tr

167 s provided by the Developmental Therapeutics Program of NIH/NCI against a panel of pathogenic fungi i

168 The Intramural Research Program of NINDS supported this study.

169 These findings suggest that the programming of NK effector function results from defined

170 A program of normothermic ex situ liver perfusion (NESLiP)

171 i and widely implicated in the developmental programs of numerous tissues.

172 i screen of NuRD target genes, we identify a program of NuRD-repressed genes that operate as critical

173 the mechanisms underlying the developmental programming of offspring phenotype by suboptimal intraut

174 onstrate that neuronal TSC1/2 orchestrates a program of oligodendrocyte maturation through the regula

175 Lineage-specific programming of oligodendrocytes results from sensing env

176 articipating in an Italian compassionate-use program of ombitasvir/paritaprevir/ritonavir + dasabuvir

177 at is required for specialized developmental programs of orchid species.

178 The distinct reproductive program of orchids provides a unique evolutionary model

179 ive repression of the entire transcriptional programs of other neural progenitor fates.

180 e the key intracellular pathways involved in programming of ovarian reserve.

181 e the key intracellular pathways involved in programming of ovarian reserve.-

182 oly-UB chains synthesized by PARKIN drives a program of PARKIN recruitment and mitochondrial ubiquity

183 subjective and objective wireless monitoring program of patient-centered outcomes can be carried out

184 We evaluated a program of payments for ecosystem services in Uganda tha

185 ts PCD to interdigital areas, as the genetic program of PCD provides the first layer and vascular pat

186 but much less is known about the replication programs of plants.

187 Overall, an aggressive global program of PM2.5 mitigation in line with WHO interim gui

188 neonatal challenges can result in long-term programming of poor offspring cardiovascular health.

189 However, many other programs of postembryonic root organogenesis exist in an

190 sferases in establishing the transcriptional program of postnatal cardiomyocytes during heart develop

191 e human gut microbiota undergoes a definable program of postnatal development.

192 the ACE inhibitor enalapril, together with a program of PR, in patients without an established indica

193 Genome-wide changes in the replication program of premeiotic S phase do not affect meiotic prog

194 breast cancer cells, IL30 boosted a broader program of proliferation, invasive migration, and an inf

195 A program of prospective measurement of BNP levels with Do

196 lose pluripotency, activate an irreversible program of prospermatogonial differentiation, and tempor

197 nd networks with atomic accuracy enables the programming of protein interaction specificity for a bro

198 To combat pollution, improved programs of public health and environmental protection a

199 We identified an emerging program of putative enhancers that revise H3.3 occupancy

200 omic epidemiological methods together with a program of rapid, effective remedial biofilm, plumbing a

201 ognition by CD4(+) T cells and establishes a program of reduced immunogenicity in recently infected B

202 id catabolism, and a dendritic-cell-specific program of regulatory CD4(+) T-cell activation.

203 Transcriptional programming of regulatory mechanisms facilitates the fun

204 study shows a 2-year beneficial effect of a program of rehabilitation maintenance on the BODE index

205 e neuronal guidance cue netrin-1 activates a program of reparative angiogenesis in microglia within t

206 The PGC has recently commenced a program of research designed to deliver "actionable" fin

207 ent cohorts of patients from the Specialized Program of Research Excellence (N = 391) and the Groupe

208 e University of Iowa/Mayo Clinic Specialized Program of Research Excellence Molecular Epidemiology Re

209 ity of Iowa/Mayo Clinic Lymphoma Specialized Program of Research Excellence).

210 ity of Iowa-Mayo Clinic Lymphoma Specialized Program of Research Excellence.

211 efficacy in the CAPRISA (Centre for the AIDS Program of Research in South Africa) 004 trial.

212 This article draws on a program of research in three American cities-Boston, Chi

213 ses, the largest RNA viruses, have a complex program of RNA synthesis that entails genome replication

214 deployment of visuospatial attention and the programming of saccades are governed by the inferred lik

215 entiation, providing insights into molecular programming of SC lineage progression and homeostasis.

216 four catalytic residues that enabled the re-programming of SdCPS2 activity to afford four distinct p

217 The result is a choreographed program of secretory, biosynthetic, and endocytic protei

218 ht zone sustain the subsequent proliferative program of selected B cells that occurs in the anatomica

219 ntrolled trials for the clinical development programs of selected allergic rhinitis treatments were e

220 nscription, with gene expression driven by a program of selective unmasking, translation, and degrada

221 B cell subsets, we observed broad epigenetic programming of selective transcription factor binding si

222 as tularemia, has been used in the bioweapon programs of several countries in the past, and now it is

223 , concurrently activates the gene expression programs of several domains.

224 meiosis, thereby enabling unique epigenetic programming of sex chromosomes for male reproduction.

225 NA accumulation just prior period of oocytes programming of sex.

226 enetic framework parallels the morphogenetic program of shoot apical meristems and may represent a re

227 nous RNA by TLR3 is an important step in the program of skin barrier repair.

228 erevisiae GAL genes thus encode a regulatory program of slow induction and avid repression, and a fit

229 e worthwhile to explore deregulated cellular programs of SMZL as therapeutic targets in the future; i

230 ctively controlling terminal differentiation programs of specific neuron types, but not in broadly co

231 itory signals of speech perception and motor programs of speech production.

232 matid-derived frog embryos, we show that the programming of sperm for successful development relates

233 This study focuses on a program of standardized nursing and physical therapy int

234 leukemogenic scenario of human ALL in which programs of stem cells are sustained in distinct fractio

235 methylation is functionally relevant for the programming of stress reactivity in the human brain.

236 Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, wh

237 The S3 Program of studies tested whether combining intervention

238 ualitative and quantitative methods within 1 program of study, is becoming increasingly popular to al

239 litical factors have not allowed vaccination programs of sustained high quality.

240 ective genes are expressed during the normal program of SVZ neurogenesis, suggesting that PBX1 might

241 conclusion, SPARC triggers a cell-autonomous program of synapse elimination in cholinergic neurons th

242 t the transcription factor NFAT controls the program of T cell exhaustion.

243 the need for innervation to drive the entire program of taste bud differentiation.

244 WHO, Global TB Program of Texas Children's Hospital.

245 However, current protocols for ex vivo programming of Th17 cells, which include TGFbeta exposur

246 e myocardial infarction in the coronary care program of the Bureau of Health Promotion were analyzed.

247 efforts such as the Hormones Standardization Program of the CDC, harmonization activities require new

248 s occurs against the ongoing transcriptional program of the cell is far from complete.

249 ion of most of the transcriptional antiviral program of the cell.

250 the continuing medical education dermoscopy program of the Claude Bernard-Lyon 1 University in Lyon,

251 tage of development when the transcriptional program of the embryo has yet to begin.

252 SCs orchestrates the stem cell-centric aging program of the epithelial mini-organ.

253 Intramural Research Program of the Eunice Kennedy Shriver National Institute

254 from the acquired immunodeficiency syndrome program of the Health Center of Duque de Caxias, Rio de

255 arises from variations in the developmental program of the individual scale cells of the wing epithe

256 a show that the imprinting of the epigenetic program of the inhibitory receptor PD-1 occurs during th

257 Intramural Research Program of the National Heart, Lung, and Blood Institute

258 The Total Worker Health (TWH) program of the National Institute for Occupational Safet

259 the Social Sciences and Intramural Research Program of the National Institutes of Health Clinical Ce

260 The intramural program of the NIEHS nurtures cutting-edge science, and

261 s and participated in the scanner validation program of the Society of Nuclear Medicine and Molecular

262 Defense Health Program of the United States Department of Defense.

263 Intramural Research Program of the US National Institute of Allergy and Infe

264 Correct gene expression programming of the cardiomyocyte underlies the normal fu

265 isease risk is largely unknown, but in utero programming of the child's immune system may play a role

266 in childhood pointing toward in utero immune programming of the child.

267 ition (over and undernutrition) on perinatal programming of the CNS and immune system, and how this m

268 These results enabled the programming of the degradation rates of the DNA-assemble

269 The programming of the fungal polyketide synthase (PKS) is q

270 Prevention programming of the future will depend on all of us havin

271 ess history, contribute to the developmental programming of the hypothalamic-pituitary-adrenal stress

272 rdioverter-defibrillators (ICDs), as well as programming of the ICD, is unclear.

273 Programming of the immune system during fetal developmen

274 nd study design considerations, 3) microbial programming of the immune system, 4) the microbiome and

275 ogether, our results indicate that the early programming of the oocyte epigenome primes meiotic chrom

276 aused by LT-IH are mediated by epigenetic re-programming of the redox state in the CB chemosensory re

277 e nucleotides (p)ppGpp, causing a massive re-programming of the transcriptional profile known as the

278 Re-programming of the transcriptome involves both transcrip

279 529 529 References 529 Re-programming of the transcriptome involves both transcrip

280 ral framework for the global gene expression programs of the individual chromosomes.

281 cells fail to adequately silence expression programs of the starting population and that the establi

282 f Hlx at a physiological level drives a full program of thermogenesis and converts iWAT to brown-like

283 ablish IRF4 as a transcriptional driver of a program of thermogenic gene expression and energy expend

284 corresponding changes in the gene expression program of these malignant cancer cells.

285 The stability of the epigenetic commitment programs of these stem cells, coupled with their unlimit

286 otein is important in understanding the gene program of this human pathogen.

287 be used in integrated pest management (IPM) programs of this pest species.

288 ng was required for residency and directed a program of tissue homing migrational cues.

289 Thus, cell-type-specific regulatory programs of tissue regeneration can be revealed by genom

290 osteric GAC inhibitors impacts the metabolic program of transformed cells.

291 both necessary and sufficient to support the programming of TRM cell fate in tissue-infiltrating T ce

292 at BACH2 is a key component of the molecular program of tumor immunosuppression and identify therapeu

293 41 could contribute to the dedifferentiation program of tumor-forming keratinocytes and to molecular

294 sequencing for studying the transcriptional programs of tumor nuclei in frozen archival tissue sampl

295 are the first to compare the transcriptional programs of two genetically distant Ads by mRNA next-gen

296 rce-limited curation, research, and breeding programs of underutilized plant genetic resources, howev

297 Because of successful programs of universal salt iodization in formerly severe

298 dverse intrauterine environment alters fetal programming of vascular reactivity in adult offspring.

299 related microcephaly clusters as a long-term program of work.

300 ut with suppression of a distinct pro-growth program of Yki-induced/Tai-dependent genes, including th