ライフサイエンスコーパス: programme

1 lessness service, and one needle and syringe programme).

2 at the end of a 30-day residential treatment programme.

3 rstand the effect on an individual country's programme.

4 amme, and as part of the routine or catch-up programme.

5 d routine care through the existing national programme.

6 Groups received a 6-month, twice weekly programme.

7 n a 48-96 week life-skills and job-readiness programme.

8 as sunrise and adjust their transcriptional programmes.

9 ost-saving, and should be adopted in all EID programmes.

10 elineate the most efficacious detoxification programmes.

11 n nature and difficult to manage in breeding programmes.

12 viral therapy (ART), and condom distribution programmes.

13 tablishment and maintenance of cell-specific programmes.

14 rsity, particularly in countries with 4CMenB programmes.

15 n response to standardized exercise training programmes.

16 important modulator of myeloid function and programming.

17 ated healthcare services along with homeless programming.

18 h realizes different functionalities through programming.

19 arly steps linked to termination of diapause programming.

20 This work opens new directions in programming 3D shapes by providing new insight into heli

21 Altogether, we programmed 4,342 overlapping 1 and 2 kb deletions that t

22 fficiently enhance child cognition, and that programmes addressing socioenvironmental determinants ar

23 ility to bTB and enhance genetic improvement programmes aiming at controlling and eradicating the dis

24 is implemented using quadratic-time dynamic programming algorithms and (ii) the majority of candidat

25 mpact despite a long established vaccination programme and approved antivirals.

26 the higher mitochondrial oxidative capacity programme and fatty acid oxidation through the AMPK/PGC1

27 explore the feasibility and costs of such a programme and its overall effect on individuals and soci

28 isk and health service provision, along with programme and policy documentation of maternal care cove

29 ts, academia, funders, and WHO to strengthen programmes and enhance research in aedes-transmitted dis

30 geted and culturally appropriate health-care programmes and services for communities with a high numb

31 ressors through augmenting psychosocial care programmes and social integration would be a key approac

32 e transcriptional regulatory specificity and programming and as a baseline that may facilitate unders

33 ansport layers, to achieve reliable and fast programming and erasing of the threshold voltage shift i

34 d that they provide an impressive variety of programming and have collectively served over 1.2 millio

35 We tested the hypothesis that enhanced TH17 programming and IL-17 expression in abundant CD161(+) im

36 While programming and theoretical analysis of tile self-assemb

37 e how early-life stress drives developmental programming and transgenerational effects of maternal ex

38 fy participants targeted in each year of the programme, and as part of the routine or catch-up progra

39 sisted gene flow, conditioning or epigenetic programming, and the manipulation of the coral microbiom

40 National programmes are needed.

41 Conversely, although most models of saccade programming are tightly coupled to underlying neurophysi

42 These data establish de novo DNA-methylation programming as a regulator of T cell exhaustion and barr

43 lial cells, some of which are epigenetically programmed at the level of miRNA regulation.

44 port the implementation of T cruzi screening programmes at primary health centres in European countri

45 e its electro-mechanical design and computer programme available online.

46 victims who were counselled by Haiti's IBCM programme between May 15, 2014, and Sept 15, 2015.

47 Here, we report the first description of AML programming bone marrow adipocytes to generate a protumo

48 ns of an identical patterned hydrogel can be programmed by the pre-swelling step with different masks

49 Such programmes can be delivered conveniently and cost-effect

50 ssing terminal transcription factors (direct programming) can generate similar fates by alternative r

51 tal origin of cardiovascular dysfunction and programme cardiovascular disease in later life.

52 ity, causing cellular stress, and increasing programmed cell death (apoptosis) in the tissues require

53 species from cells or to selectively induce programmed cell death (apoptosis) or uncontrolled cell d

54 d play a central role in the early stages of programmed cell death (apoptosis).

55 D-L1) to enrich for patient response to anti-programmed cell death 1 and anti-PD-L1 therapies.

56 In this study, we demonstrate that programmed cell death 1 ligand 2 (PD-L2) regulates the p

57 To determine the efficacy of programmed cell death 1 receptor (PD-1) inhibitors in lo

58 T cells, such as programmed death-ligand 1, programmed cell death 1, or transforming growth factor b

59 red CD20+ B cells, and relatively few PD-1+ (programmed cell death 1-positive) T cells, an immunophen

60 Programmed cell death 4 (Pdcd4), a tumor invasion suppre

61 gation of peroxisomes during final stages of programmed cell death and can be used as a marker of thi

62 hrough a recently described distinct form of programmed cell death called NETosis.

63 Furthermore, programmed cell death can also represent a defense mecha

64 Necroptosis is a form of programmed cell death defined by activation of the kinas

65 (ECM) is required to combat the induction of programmed cell death in a variety of distinct cell type

66 ) family, which are emerging as mediators of programmed cell death in a variety of processes that reg

67 icum) Cipk6 regulates immune and susceptible Programmed cell death in immunity transforming Ca(2+) si

68 plicated its role in signaling to SI-induced programmed cell death involving a DEVDase.

69 tibody) in advanced solid tumours expressing programmed cell death ligand 1 (PD-L1) and report here o

70 Programmed cell death ligand 1 (PD-L1) is part of an imm

71 US Food and Drug Administration (FDA) detect programmed cell death ligand 1 (PD-L1) to enrich for pat

72 ts of IFN-gamma and sensitize tumors to PD-1/programmed cell death ligand 1 blockade-induced rejectio

73 cells undergoing apoptosis, suggesting that programmed cell death may limit viral dissemination in t

74 Programmed cell death occurs in a highly reproducible ma

75 n, and vRNP sensing to trigger activation of programmed cell death pathways during IAV infection.

76 This study reveals the effect of antiviral programmed cell death pathways on inflammation, shows th

77 luenza virus infection induces activation of programmed cell death pathways.

78 that most hypertrophic chondrocytes undergo programmed cell death prior to bone formation.

79 Blocking programmed cell death protein (PD)-1 signaling, which me

80 une checkpoints, such as the one mediated by programmed cell death protein 1 (PD-1) and its ligand PD

81 The programmed cell death protein 1 (PD-1) and programmed de

82 Signaling between programmed cell death protein 1 (PD-1) and the PD-1 liga

83 as performed to assess CD8, FOXP3, CD56, and programmed cell death protein 1 (PD-1) expression on str

84 Rgammat(+) T cells expressing a low level of programmed cell death protein 1 and a high level of OX40

85 n recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)-mediated

86 afety and efficacy of pembrolizumab (an anti-programmed cell death receptor 1 [PD-1] antibody) in adv

87 ety and potential benefit of nivolumab (anti-programmed cell death receptor 1) monotherapy beyond Res

88 Ferroptosis is a form of programmed cell death that is pathogenic to several acut

89 Necroptosis is a highly inflammatory form of programmed cell death that results from MLKL-mediated di

90 nhibitor 1 (BI1) modulates ER stress-induced programmed cell death through yet-unknown mechanisms.

91 Programmed cell death widely but heterogeneously affects

92 s in the nuclear architecture, and activated programmed cell death, in D. citri midgut cells.

93 epidermal patterning, vascular development, programmed cell death, organ abscission, senescence, and

94 Ligation of programmed cell death-1 (PD-1) in the tumor microenviron

95 Programmed cell death-1 (PD-1) is an inhibitory receptor

96 l immunoglobulin and mucin-3 (TIM-3), and/or programmed cell death-1 (PD-1), and acquire an anergic p

97 Programmed cell death-1 (PD-1)-targeted therapies enhanc

98 Programmed cell death-1 mRNA expression was increased in

99 daptive immunity; and dormancy induction, or programmed cell death.

100 ich govern the edibility of cells undergoing programmed cell death.

101 ive transcriptional strategies for metabolic programming, cell cycle control and functional polarizat

102 The anti-Programmed cells Death-1 was stopped and a topical corti

103 have shown that reduced perinatal nutrition programmes chronic cardiovascular disease.

104 gradually more complex examples, along with programming code and data sets, to show how Bayesian ana

105 mplant-related complications, basic function/programming, common pacemaker-related issues, and remote

106 ) and a powered knee prosthesis with two pre-programmed controller settings (i.e. for load and no loa

107 predicted to lead to a reduction of overall programme cost.

108 ve (TW) based compression ratio ion mobility programming (CRIMP) approach within structures for lossl

109 s, the molecular mechanism for regulation of programmed death 1 (PD-1) and its ligand (PD-L1) is part

110 Response to programmed death 1 (PD-1) inhibitors has been associated

111 esponsive to immune checkpoint blockade with programmed death 1 (PD-1) targeted agents, novel immunot

112 ld only partly be rescued by blockade of the programmed death 1 pathway.

113 Immunotherapeutic approaches, particularly programmed death 1/programmed death ligand 1 (PD-1/PD-L1

114 approaches, particularly programmed death 1/programmed death ligand 1 (PD-1/PD-L1) blockade, have im

115 1 (PD-1) inhibitors has been associated with programmed death ligand 1 (PD-L1) expression levels in s

116 nivolumab with chemotherapy in patients with programmed death ligand 1 (PD-L1)-positive NSCLC.

117 Programmed death ligand-1 (PD-L1) interacts with program

118 l immunity via the programmed death-1 (PD-1)-programmed death ligand-1 (PD-L1) pathway.

119 lymphocyte-associated protein 4 (CTLA-4) and programmed death receptor 1 (PD-1) were ineffective in c

120 The interactions between programmed death-1 (PD-1) and its ligands hamper tumor-s

121 monoclonal antibody that inhibits PD-L1 and programmed death-1 (PD-1) and PD-L1 and B7-1 interaction

122 rammed death ligand-1 (PD-L1) interacts with programmed death-1 (PD-1) and the immunostimulatory mole

123 g antitumor adaptive T cell immunity via the programmed death-1 (PD-1)-programmed death ligand-1 (PD-

124 his is the largest analysis of data for anti-programmed death-1 therapy in mucosal melanoma to date.

125 cell coinhibitory receptors CTLA-4 and PD-1 (programmed death-1) that have shown activity in several

126 mor activity of avelumab, a fully human anti-programmed death-ligand 1 (PD-L1) IgG1 antibody, in pati

127 the role of Toll-like receptor 2 (TLR2) and programmed death-ligand 1 (PD-L1) in regulating alpha-(1

128 e programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) pathway play an import

129 the regulatory pathways in T cells, such as programmed death-ligand 1, programmed cell death 1, or t

130 IgD and/or IgM expression (67%), and lack of programmed death-ligand 1/ligand 2.

131 idence for the benefits of parenting support programmes delivered by nurses on a range of health outc

132 Temperature-programmed desorption and X-ray photoelectron spectrosco

133 Our findings suggest that programmed differences in infant stem cell metabolism co

134 During meiotic recombination, a subset of programmed DNA double-strand breaks (DSBs) are repaired

135 We precisely map RNA-programmed DNA methylation to targeted CpG sites as a fu

136 he Siberian hamster (Phodopus sungorus), the programming effect of melatonin is mediated by the pars

137 Together, these programmed effects will potentially create an imbalance

138 diet early in life has modest but persistent programming effects on bone formation to prevent OVX-ind

139 Programmed electric stimulation demonstrated increased s

140 HFpEF-verified and control rats underwent programmed electrical stimulation.

141 e modes capable of multi-modal nanolasing at programmed emission wavelengths and with large mode spac

142 s a flexible, feature-rich, high-performance programming environment for analysis of WGS variant data

143 rt education initiatives in mechatronics and programming, equivalent connections to the life sciences

144 he data, and check for statistical errors or programming errors.

145 yter), OMAAT is accessible to anyone without programming experience yet allows experienced users to l

146 view five software tools that do not require programming expertise.

147 ccal meningitis is a metric of HIV treatment programme failure; timely HIV testing and rapid linkage

148 The Malawian Farm Input Subsidy Programme (FISP) has received praise as a proactive poli

149 uctive, maternal, neonatal, and child health programmes focused on biomedical determinants might not

150 he USDA Forest Service Slow the Spread (STS) programme for managing the future spread of gypsy moth h

151 scle development, and define a two-component programme for the induction of mammalian cell fusion.

152 A pivotal clinical programme for the investigation of brexanolone in patien

153 rough GAVI and the Global Fund, and used for programmes for new and underused vaccines, HIV/AIDS, mal

154 ge of NSP, OST, HIV testing, ART, and condom programmes for PWID.

155 Necroptosis, a programmed form of necrosis, is executed by the mixed li

156 ils away from phagocytosis of ICs toward the programmed form of necrosis, NETosis.

157 Through regulation, education, and support programmes, governments can create an environment in whi

158 In conclusion, the possibility of programming gradient of temperature in the coffee machin

159 Two participants in the 12-week programme had been found to be ineligible shortly after

160 intervention, which corresponded to a custom-programmed hard-stop alert tool in the Epic hospital inf

161 ) for HIV prevention through syringe service programmes has the potential to save lives and be cost-e

162 how data from a large-scale pest management programme have provided important contributions to the f

163 The data from this programme have provided the foundation for investigation

164 Traditional insecticide-based vector-control programmes have limited effectiveness, and the one licen

165 ce is an intrinsic part of the developmental programme in amphibians.

166 ty after the roll-out of a public sector ART programme in KwaZulu-Natal, South Africa, one of the pop

167 men in Cambodia and Indonesia, UN Develoment Programme in Papua New Guinea, and CARE in Sri Lanka.

168 NTERPRETATION: A grass-roots community-based programme in rural India was associated with substantial

169 five countries that had a compassionate use programme in which patients underwent transcatheter mitr

170 We propose that cell division arrest is programmed in competent pneumococcal cells to ensure tha

171 Nuclear actin regulates transcriptional programmes in a manner dependent on its levels and polym

172 s when implementing diabetes self-management programmes in different areas.

173 s the subsequent activation of distinct fate programmes in each daughter.

174 r the induction of different transcriptional programmes in LCs.

175 d be considered as part of male circumcision programmes in other sub-Saharan African countries.

176 standardised second-line regimen for use in programmes in resource-limited settings.

177 tiveness of confirmatory HIV testing for EID programmes in South Africa.

178 g child survival through enhanced policy and programmes in the Sustainable Development Goals era.

179 Some nurse-led self-management programmes in this systematic review produced beneficial

180 indicating a potential role for nutritional programming in the early origins of obesity, but interge

181 elta T cells instead can be 'developmentally programmed' in the thymus to generate discrete gammadelt

182 Maternal obesity programmed increased adiposity and liver triglycerides,

183 ew questions as part of an interdisciplinary programme integrating linguistics and psychology as part

184 erate with the GDC using the GDC Application Programming Interface (API).

185 base also offers data access via Application Programming Interfaces (APIs) and in various standardize

186 list, to provide either a weight management programme (intervention) or best-practice care by guidel

187 hat MkMP RNA is largely responsible for HSPC programming into Mk differentiation.

188 lecular pathways that direct differentiation programmes involving the haemato-endothelial lineages.

189 An interesting aspect of developmental programming is the existence of transgenerational effect

190 and implementing this algorithm in the fast programming language C++.

191 data files, which are easily parsed with any programming language or viewed in a browser.

192 and manipulation using Python and any other programming language that implements a JSON parser/gener

193 Our computer program-MIDcor written in the R programming language, corrects the raw MS spectra both f

194 depending on the computational platform and programming language, either ByRow or ByBox give best ru

195 s a JSON parser/generator (i.e., all popular programming languages).

196 de-ranging impact of sSNPs, which invert the programmed local speed of mRNA translation and provide d

197 Participants in the behavioural programme lost more weight than those in the brief inter

198 idly converged by iteratively solving linear programming (LP) problem and the number of iterations is

199 demonstrated that nurse-led self-management programmes may be associated with reductions in anxiety

200 ent FastRFS, a new method based on a dynamic programming method we have developed to find an exact so

201 Using a linear programming model, we ask when a colony should produce d

202 Using a cell-free gene network we programmed molecular interactions that control the frequ

203 a framework to achieve the ambitious goal of programming morphogenesis in complex tissues and organoi

204 the brief intervention (n=211), the 12-week programme (n=528), and the 52-week programme (n=528).

205 e 12-week programme (n=528), and the 52-week programme (n=528).

206 led that cystine deprivation triggered rapid programmed necrosis, but not apoptosis, in the basal-typ

207 One such mechanism in vertebrates is programmed necrosis, or "necroptosis", driven by recepto

208 ctivation, we propose that they are forms of programmed necrosis.

209 appointment within the NHS Breast Screening Programme (NHSBSP).

210 ventions for PWID include needle and syringe programmes (NSP), opioid substitution therapy (OST), HIV

211 tients and all clinicians other than the DBS programming nurse were masked to the choice of lead.

212 f the centre, and enacted by an unmasked DBS programming nurse).

213 odel to account for their formation from the programmed octaketide of the enediyne PKS.

214 spectively, by tuning the periodic-branching programme of epithelial progenitors.

215 ATION: Systematic, community-based screening programme of fracture risk in older women in the UK is f

216 ations (ie, after completion of the expanded programme of immunisation schedule): 1/3 IPV-Al 98.5% (n

217 This approach uncovers a wide programme of neuron-induced astrocytic gene expression,

218 Grounded in a substantial programme of research on healthcare work, it has value f

219 ed part of a European project (7th Framework programme of the European Commission) exploring the link

220 nd place it as a critical regulator of fetal programming of adult metabolic disease.

221 mplicity of the t2M/t4M binding site enables programming of allostery in RNAs, recoding oligo-U domai

222 contributions of each of these stressors to programming of cardiovascular dysfunction.

223 lutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses to vir

224 ects offspring from WD-induced developmental programming of hepatic lipotoxicity and may help slow th

225 ethnically diverse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRIS

226 otential of alpha7nAChR agonists in early re-programming of microglia in neonates exposed to in utero

227 his transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restr

228 Transcriptional programming of regulatory mechanisms facilitates the fun

229 Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, wh

230 in childhood pointing toward in utero immune programming of the child.

231 aused by LT-IH are mediated by epigenetic re-programming of the redox state in the CB chemosensory re

232 The Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets require

233 e coverage of OPV, IPV, and routine extended programme on immunisation vaccines and changes in the pr

234 has traditionally been limited to static pre-programmed or operator-controlled protocols.

235 ledge, and receipt of cancer surveillance in programme participants.

236 r and based on a close collaboration between programme partners and manufacturers, the cessation of a

237 Later, the direct programming path diverges into a novel transitional stat

238 max) seed coat has distinctive, genetically programmed patterns of pigmentation, and the recessive k

239 We anticipate that sequence-specific programmed peptides will offer promise as design element

240 ement; the device had not been appropriately programmed per protocol before the MRI.

241 This programming plays a key role in the plague-resistance ph

242 h patterns and investigate early nutritional programming potential on growth patterns at 6 y and on b

243 ic respiratory disease, and blindness health programmes; provision of enhanced laboratory capacity to

244 antibiotic formulary, antibiotic stewardship programmes, public health interventions, infection contr

245 ppraisal tool (The Critical Appraisal Skills Programme Qualitative Research Checklist and Paterson et

246 From temperature-programmed reaction spectroscopy experiments, we found t

247 The programmed-reassembly of thermal shifters inspired by LE

248 Our results suggest that whilst programmed reductions in IRS-1 are associated with incre

249 How differentiation in direct programming relates to embryonic differentiation is uncl

250 Biofilm dispersal is a genetically programmed response enabling bacterial cells to exit the

251 The programmed self-destruction of infected cells is a power

252 ide a versatile platform for genetically pre-programming self-assembly into micelles of varied size a

253 tion after 144 weeks of follow-up in typical programme settings.

254 HIV/AIDS programmes should consider point-of-care CRP-based tuber

255 ctively as a self-guided digital audiovisual programme, so might also reduce health-care costs.

256 hetic antenna proteins can be thought of as "programmed solvents", which bind pigments at specific mu

257 irect Lactococcus lactis populations to form programmed spatial band-pass structures that do not requ

258 growth progresses through three genetically programmed stages: substratum attachment, intercellular

259 bottom electrode, it is shown that SET/RESET programmed states form via the formation/annihilation of

260 anded evaluations can include assessments of programme structure; long-term outcomes, such as surviva

261 jasmonate (MeJA)-triggered transcriptome re-programming substantially overlapped with defense respon

262 ion network, Bayesian network, semi-definite programming-support vector machine (SDP-SVM), relevance

263 thoxymethyl)-pyrrolidine], thus enabling the programmed synthesis of polypropionates in a fully stere

264 Survivorship programmes tend to evaluate their effectiveness by asses

265 s a community-based primary healthcare (PHC) programme that has been expanding since the 1990s and is

266 e we describe a multinational drug discovery programme that has delivered a synthetic tetraoxane-base

267 cal Trials Unit, where staff used a computer programme that implemented a minimisation algorithm with

268 ered by JavaScript, the lingua franca of web programming, these 'web apps' are starting to revolution

269 As for launching a programme to interrupt transmission, two interlinked too

270 nostructures have been developed, few can be programmed to assemble structures whose form depends on

271 e we describe a molecular system that can be programmed to control these three characteristics.

272 ilities where photonic elements can be field programmed to deliver complex, system-level functionalit

273 rigger death only in daughter cells that are programmed to die.

274 d >/=18 years installed a mobile application programmed to geofence all hospitals using global positi

275 Pancreatic beta cells are functionally programmed to release insulin in response to changes in

276 This molecular robot can be programmed to stereoselectively produce, in a sequential

277 ructured state without constraint and can be programmed to terminate their folding process at differe

278 stream-form type transcriptome, and thus are programmed to translate a bloodstream-form type proteome

279 The use of integrated programmes to align justice and health-care goals has gr

280 and permitted common features of successful programmes to be identified.

281 opriate resource utilisation; and ability of programmes to increase access to needed survivorship car

282 fore, how to incorporate them into emergency programmes to maximise their success in terms of improve

283 his paper, we demonstrate the use of genetic programming to generate simple models of dielectric brea

284 assessed using the Critical Appraisal Skills Programme tool for health economic evaluations.

285 Critical Appraisal Skills Programme tools were used to assess the quality of the i

286 using the relevant Critical Appraisal Skills Programme tools.

287 y of lymphoid progenitors, preventing B cell-programming transcription factors from prematurely enact

288 dhood, defined as preadolescence, alters the programming unique to this period of brain maturation an

289 d 24-node silicon photonic neural network is programmed using "neural compiler" to solve a differenti

290 wide receive antiretroviral therapy (ART) in programmes using WHO-recommended standardised regimens.

291 tative, and fertility preservation services; programme value, including costs and avoidance of inappr

292 etween the SPOP(MT) and c-MYC transcriptomic programmes, was also associated with inferior clinical o

293 implementation of a national sex worker HIV programme, which could have also affected uptake and ret

294 llows for initiation, signaling, and logical programming, which are necessary for making enclosed, hi

295 a biochemical method (SITE-Seq), using Cas9 programmed with single-guide RNAs (sgRNAs), to identify

296 rly diagnosis, treatment and supportive care programmes with the potential to achieve measurable outc

297 Introduction of such a PrEP programme, with around 4000 MSM initiated on PrEP by the

298 ng community health workers in public sector programmes working in similar circumstances with such co

299 referral to an open-group weight-management programme would achieve greater weight loss and improvem

300 nd/or OVX, independent of previous postnatal programming, yet only HFD evoked this effect in liver.