ライフサイエンスコーパス: programming of

1 within less than 5 s using fast temperature programming of a 0.5-m-long microbore column.

2 Our data provide experimental evidence of programming of a cardiovascular risk factor by early die

3 node- derived and other local signals in the programming of a Hox pattern at posterior spinal levels.

4 ence and kinetics can be rewired through the programming of a sequence motif of the general form G-G/

5 fine a mechanism for Stat4-dependent genetic programming of a Th1-associated gene.

6 onscious representations encompass the motor programming of actions that could be accomplished congru

7 e GR and PGC-1alpha participate in the fetal programming of adult beta-cell function through inhibiti

8 Fetal growth plays a role in programming of adult cardiometabolic disorders, which in

9 overnutrition during pregnancy affect fetal programming of adult disease.

10 extend the concept of fetal and early infant programming of adult diseases to the immune system and s

11 of pregnancy complications and the in utero programming of adult diseases.

12 rnal protein restriction is a model of fetal programming of adult glucose intolerance.

13 Fetal programming of adult glucose metabolism may operate part

14 maturity in the Preterm Birth and Early Life Programming of Adult Health and Disease (ESTER) Study, a

15 maternal nutrition can induce developmental programming of adult hypertension in offspring.

16 nd place it as a critical regulator of fetal programming of adult metabolic disease.

17 idence in support of prenatal glucocorticoid programming of adult ND over 40 years in daughters only.

18 underlying fetal growth restriction and the programming of adverse health outcomes in the adult.

19 Our data suggest that developmental programming of aging importantly contributes to (and per

20 mplicity of the t2M/t4M binding site enables programming of allostery in RNAs, recoding oligo-U domai

21 diet for the remainder of gestation, induced programming of altered birthweight, postnatal growth rat

22 As, and it is thought that this prevents the programming of an antiviral RNA-induced silencing comple

23 and antidepressant responses via epigenetic programming of an xCT-mGlu2 network.

24 r mineralization by directing the osteogenic programming of aortic progenitors in diabetic arterioscl

25 ults demonstrate that the cell type-specific programming of apparently committed primary progenitors

26 (Wnt) superfamilies, are also active in the programming of arterial osteoprogenitor cells during vas

27 Such a method would also guide more optimal programming of automated external defibrillators.

28 ld be used as a control signal for automated programming of basal ganglia stimulators.

29 vel function of Id1 in BAT thermogenesis and programming of beige adipocytes in white adipose tissue

30 may partly arise from altered developmental programming of beta-cells.

31 odule for the Drupal CMS that simplifies the programming of bioinformatic Drupal modules.

32 tions related to implantation, hardware, and programming of biventricular devices.

33 Intrauterine programming of body composition [percentage body fat (%B

34 data provide key insights into the metabolic programming of border cells that strongly implicate a mo

35 play a prominent role in the organization or programming of brain circuits, which are subsequently ac

36 ne the role of the fetal PT in developmental programming of brain function by maternal melatonin and

37 sight into how IGF-1 signaling modulates the programming of cardiac muscle gene expression.

38 igenetic modification of DNA methylation and programming of cardiac PKCepsilon gene repression in a s

39 ating cardiovascular aging and developmental programming of cardiovascular disease, and aging being d

40 ating cardiovascular aging and developmental programming of cardiovascular disease.

41 contributions of each of these stressors to programming of cardiovascular dysfunction.

42 lutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses to vir

43 that the LTbetaR/IFN-I axis is essential for programming of CD8(+) T cells to mediate immunopathology

44 identify a role for 1,25D3 in the molecular programming of CD8(+) T-cell conversion to an IL-13-secr

45 Functional studies show that programming of CD8+ T cells occurs early after initial a

46 ive model of cytokine-driven transcriptional programming of cell fate decisions.

47 lay a specific regulatory role in epigenetic programming of cell lineage because it is ubiquitously e

48 form studies of aging and enable the precise programming of cellular age in parallel to cell-fate spe

49 , and the GATA family, which participates in programming of cellular differentiation.

50 develop engineering-driven approaches to the programming of cellular functions that could yield trans

51 The programming of cellular networks to achieve new biologic

52 canola seed development disrupts the normal programming of Chl degradation, resulting in green seed

53 not amenable to selective ERRgamma-directed programming of classic exercise-like effects in the skel

54 -clustering algorithm (ChAT) employs dynamic programming of combinatorial histone modification profil

55 modifiable targets to prevent developmental programming of common diseases.

56 genetic mechanisms that govern developmental programming of cotton fiber morphogenesis in these two c

57 g a key role of Tsc1 in modulating metabolic programming of DC differentiation.

58 ent myofibers leads to altered developmental programming of developing and regenerating myofibers.

59 expressed coincident with the timing of sex programming of developing oocytes by methyl farnesoate i

60 tion of IL-2 to the expansion and functional programming of developing Tregs.

61 Developmental programming of diabetes in these mice was assessed from

62 stem (ES) cells can erase the developmental programming of differentiated cell nuclei and impose plu

63 in studying mechanisms involved in abnormal programming of differentiating estrogen-target tissues,

64 potential etiological mechanism for in utero programming of disease.

65 t had no significant affect on developmental programming of dissacharidases.

66 uggested to play a role in the developmental programming of dysmetabolism based on studies of human s

67 ection, we analyzed the requirements for the programming of effector and memory T cell development in

68 selective set of IL-12-induced genes to the programming of effector functions within the stable popu

69 reveal a role for the placenta in long-term programming of emotional behaviour.

70 estrogenic activity, are able to disrupt the programming of endocrine signaling pathways established

71 stable and regulated gene silencing through programming of endogenous microRNA pathways.

72 lifelong persistence of such "developmental programming" of energy balance.

73 ductive tissue which dictates organ-specific programming of epithelial tissues.

74 Preferential epigenetic programming of estrogen response after in utero xenoestr

75 selectively altered the normal developmental programming of estrogen-responsive genes via modificatio

76 s may contribute to sexual dimorphism in the programming of exaggerated cortisol regeneration in live

77 ced these cells in vivo, indicating abnormal programming of Fas-deficient T cells before the DNT stag

78 n this study, we provide evidence for immune programming of fetal loss in response to polyinosinic:po

79 Here, we describe the rational programming of function in a de novo designed di-iron ca

80 understanding the biosynthetic mechanism and programming of fungal PKSs.

81 In this way, temporal programming of gelation was possible under mild conditio

82 no known function and may contribute to the programming of gene expression and embryo development.

83 modifications and their exploitation in the programming of gene expression during several events in

84 hypothesized that BPA may disrupt epigenetic programming of gene expression in the brain.

85 offspring behavior by disrupting epigenetic programming of gene expression in the brain.

86 tages of development, to the clearing and re-programming of gene expression necessary to transition f

87 between parental genomes, leading to altered programming of genes that promote the growth, stress tol

88 critical role in the formation and metabolic programming of glycolytic myofibers in skeletal muscle.

89 tpartum element in metabolic and immunologic programming of health of neonates.

90 ong-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in

91 ects offspring from WD-induced developmental programming of hepatic lipotoxicity and may help slow th

92 t that RSK2 is involved in the prometastatic programming of HNSCC cells, through phosphorylation of p

93 tic islet formation, as well as to life-long programming of hormonal determinants of glucose homeosta

94 Studies of the programming of Hox patterns at anterior spinal levels su

95 he tailbud are primarily responsible for the programming of Hoxd10 at neural plate and the earliest n

96 e know relatively little about the molecular programming of HSCs during vertebrate embryogenesis.

97 Does developmental programming of human body weight regulation occur via ep

98 duced steroids acutely to PNS rats overrides programming of hyperactive HPA axis responses to immune

99 imal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the of

100 he PVH appears to be required for early-life programming of hypertension arising from either maternal

101 the understanding of the mechanism of fetal programming of hypertension.

102 le for DNA methylation in mediating neonatal programming of hypoxic sensitivity and the ensuing auton

103 Programming of ICD therapies for tachyarrhythmias of 200

104 (Comparison of Empiric to Physician-Tailored Programming of ICDs [EMPIRIC], Multicenter Automatic Def

105 eripheral environmental context in long-term programming of immune dysfunction.

106 It is possible that the early programming of immune function may be mediated through a

107 lity to tuberculosis, possibly through early programming of immunity.

108 suggests possible implications for long-term programming of immunity.

109 Therefore, to explore the programming of immunological sensitization by the skin,

110 (Comparison of Empiric to Physician-Tailored Programming of Implantable Cardioverter Defibrillators T

111 cal trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (

112 The programming of implantable cardioverter-defibrillators (

113 e to the disruption of the normal epigenetic programming of imprinted loci in somatic tissues and/or

114 systems analyses with regard to the dynamic programming of innate leukocytes are lacking.

115 dverse conditions in utero, to developmental programming of insulin resistance remain unknown.

116 ethnically diverse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRIS

117 light evolutionarily conserved and divergent programming of intestinal DCs.

118 Remarkably, somatic genetic re-programming of intracellular clocks in SCN astrocytes wa

119 The mechanism of programming of iterative highly reducing polyketide synt

120 e fetal kidney, effects that likely underpin programming of kidney development and function by a mate

121 ossible mechanism for maintaining epigenetic programming of large-scale chromatin domains throughout

122 for prenatal growth, but evidence for fetal programming of later FM or central adiposity is weak.

123 leptin concentrations relative to fat mass, programming of leptin concentrations may be one mechanis

124 important implications for the intrauterine programming of life expectancy.

125 It allows programming of lytic phages to kill only antibiotic-resi

126 nt of this receptor network in the metabolic programming of macrophages and dendritic cells (DCs), es

127 that miR-155 plays a key role in atherogenic programming of macrophages to sustain and enhance vascul

128 one marrow (BM) stem/progenitor cells in the programming of macrophages toward a proinflammatory phen

129 The results provide evidence of in vivo programming of macrophages within the retina.

130 Thus, intrinsic transcriptional programming of maternal serotonergic activity determines

131 Thus, intrinsic transcriptional programming of maternal serotonergic activity determines

132 ts suggest that RUNX1 may participate in the programming of megakaryocytic lineage commitment through

133 tor CTL, and demonstrate that IL-2-dependent programming of memory CD8(+) T cells capable of secondar

134 ent a novel strategy to offset dysfunctional programming of memory CD8+ T cells.

135 cells and nonhematopoietic cells blocked the programming of memory precursors essential for establish

136 nical intervention against the developmental programming of metabolic disease resulting from prenatal

137 tissues is fundamental to the developmental programming of metabolic syndrome, but underlying mechan

138 otential of alpha7nAChR agonists in early re-programming of microglia in neonates exposed to in utero

139 lpha (HIF1alpha) mediated this functional re-programming of monocytes, revealing a potential mechanis

140 nsistent with a role for Hcrt in the central programming of motor activity.

141 Here, we prove that metabolic programming of MSCs by oxygen tension directs chondrogen

142 In conclusion, metabolic programming of MSCs by oxygen tension provides a simple

143 his transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restr

144 , implying a critical role for PGI(2) in the programming of "natural" gammadelta-17 cells.

145 neuronal ensembles and perform rapid genetic programming of neural circuits.

146 an in vivo - in vitro model of developmental programming of neuroinflammation induced by lipopolysacc

147 RNA splicing plays a critical role in the programming of neuronal differentiation and, consequentl

148 To investigate the epigenetic programming of niche cells by Piwi, we screened mutation

149 However, epigenetic programming of niche cells remains unexplored.

150 These findings suggest that the programming of NK effector function results from defined

151 ociations provide some evidence for in utero programming of offspring appetite by maternal intake dur

152 rition during pregnancy is implicated in the programming of offspring for the development of obesity

153 Results do not support androgen programming of offspring ND.

154 the mechanisms underlying the developmental programming of offspring phenotype by suboptimal intraut

155 Lineage-specific programming of oligodendrocytes results from sensing env

156 fector cells that are generated but also the programming of ones that will differentiate into memory.

157 Msx 2, osterix, and RUNX2 are crucial in the programming of osteogenesis.

158 e the key intracellular pathways involved in programming of ovarian reserve.

159 e the key intracellular pathways involved in programming of ovarian reserve.-

160 del to explain our results combining genetic programming of overall vascular architecture with hemody

161 ters that may be fundamental to anticipatory programming of p53 response genes upon stress.

162 We conclude that programming of pancreatic insulin secretion responsivene

163 Genetic programming of peptidomimetic synthesis should facilitat

164 y in adult offspring, suggesting an in utero programming of PKCepsilon gene expression pattern in the

165 Recent studies demonstrate that fetal programming of PKCepsilon gene repression results in isc

166 o stress-induced jasmonates cause genetic re-programming of plant cells?

167 We discuss the concept that programming of plant development involves supracellular

168 g from the order of active-site domains, the programming of polyketide biosynthesis by modular PKSs i

169 neonatal challenges can result in long-term programming of poor offspring cardiovascular health.

170 Our data indicate that long-term programming of postnatal growth and physiology can be in

171 In an effort to perturb the programming of proliferation and differentiation in a su

172 nd networks with atomic accuracy enables the programming of protein interaction specificity for a bro

173 s the need for venous access and complicated programming of pumps.

174 the lumbosacral region to examine the early programming of regional characteristics within the poste

175 Transcriptional programming of regulatory mechanisms facilitates the fun

176 Programming of relative leptin concentrations by early d

177 ollution may play an important role in early programming of respiratory health and is potentially ame

178 isual function, likely through developmental programming of retinal dopamine.

179 ulators are key components for the intrinsic programming of RPCs and are essential for the formation

180 deployment of visuospatial attention and the programming of saccades are governed by the inferred lik

181 fined the role of the superior colliculus in programming of saccades, and the nucleus reticularis teg

182 ibuted network of structures involved in the programming of saccadic eye movements.

183 entiation, providing insights into molecular programming of SC lineage progression and homeostasis.

184 four catalytic residues that enabled the re-programming of SdCPS2 activity to afford four distinct p

185 role not only in perception but also in the programming of selective reaches.

186 B cell subsets, we observed broad epigenetic programming of selective transcription factor binding si

187 meiosis, thereby enabling unique epigenetic programming of sex chromosomes for male reproduction.

188 NA accumulation just prior period of oocytes programming of sex.

189 lower defibrillation threshold and simplify programming of shock intensity.

190 thways, especially those regulating vascular programming of solid tumors.

191 of speech', a disorder of motor planning and programming of speech.

192 matid-derived frog embryos, we show that the programming of sperm for successful development relates

193 w such links between intrinsic and extrinsic programming of stem cells have been reported previously.

194 rocess, as well as the potential for ex vivo programming of stem cells toward a renal lineage.

195 en focused on niche signaling and epigenetic programming of stem cells.

196 Here, we review the epigenetic "programming" of stem cells into oligodendrocytes, by ana

197 iding a system-wide view of the quantitative programming of storage carbohydrate metabolism.

198 methylation is functionally relevant for the programming of stress reactivity in the human brain.

199 Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, wh

200 sponse to smallest errors and influences the programming of subsequent movements.

201 When searching with our eyes, parallel programming of successive eye movements ensures that vis

202 lexible docking system, allows sophisticated programming of surface patches by the user via a facet r

203 hat in contrast to expansion, the functional programming of T cell effector and memory responses in v

204 ta thus illustrate that Bcl6 is required for programming of T(FH) cell generation.

205 s, and highlight a central role of metabolic programming of T(reg)-cell suppressive activity in immun

206 lowing the fine-tuning of expression levels, programming of temporal dynamics, and control of microbi

207 T cells is critically required for the early programming of Th17 cell lineage and Th17 cell-mediated

208 However, current protocols for ex vivo programming of Th17 cells, which include TGFbeta exposur

209 splay (BIND) as a strategy for the molecular programming of the bacterial extracellular matrix materi

210 Correct gene expression programming of the cardiomyocyte underlies the normal fu

211 regnancy, protecting the fetus from abnormal programming of the cardiovascular system.

212 Recent studies suggest that developmental programming of the carotid body response to hypoxia invo

213 ress whether TRAIL plays a role in the early programming of the CD8(+) T cell response, we performed

214 -10 may be temporarily stimulatory; however, programming of the cells may be altered, resulting in di

215 isease risk is largely unknown, but in utero programming of the child's immune system may play a role

216 in childhood pointing toward in utero immune programming of the child.

217 ition (over and undernutrition) on perinatal programming of the CNS and immune system, and how this m

218 These results enabled the programming of the degradation rates of the DNA-assemble

219 l in consequent placental function and hence programming of the fetus.

220 The programming of the fungal polyketide synthase (PKS) is q

221 during spermatogenesis, including epigenetic programming of the future paternal genome during spermat

222 Prevention programming of the future will depend on all of us havin

223 The primary periods for epigenetic programming of the germ line are those associated with p

224 r there is a critical window for nutritional programming of the growth trajectory during the first 9

225 reactivity later in life, mediated via fetal programming of the HPA axis through decreased glucocorti

226 ess history, contribute to the developmental programming of the hypothalamic-pituitary-adrenal stress

227 Programming of the hypothalamo-pituitary-adrenal (HPA) a

228 rdioverter-defibrillators (ICDs), as well as programming of the ICD, is unclear.

229 entified but also results from inappropriate programming of the immune response.

230 Programming of the immune system during fetal developmen

231 nd study design considerations, 3) microbial programming of the immune system, 4) the microbiome and

232 , we explored the possibility of temperature programming of the latter step.

233 blood formation, further distinguishing the programming of the long- and short-term blood population

234 this experiment revealed a massive temporal programming of the M. tuberculosis transcriptome.

235 ve period of early gestation when epigenetic programming of the male germline can occur, permitting t

236 This requires re-programming of the mechanisms that, in the absence of ap

237 Further evidence for developmental programming of the metabolic syndrome has now been sugge

238 ed that oxygen tension resulted in metabolic programming of the MSCs directing chondrogenesis into ar

239 l embedding is hypothesized to occur through programming of the neural circuitry that influences phys

240 that this ubiquitin ligase orchestrates the programming of the neural progenitors that give rise to

241 long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene

242 dds a life history perspective, arguing that programming of the offspring may in some species benefit

243 ogether, our results indicate that the early programming of the oocyte epigenome primes meiotic chrom

244 Because the physiologic programming of the placenta across gestation is likely t

245 ostimulation during the later phase, but not programming of the primary CD8+ T cell response to influ

246 Programming of the primary T cell response is BCR/B cell

247 aused by LT-IH are mediated by epigenetic re-programming of the redox state in the CB chemosensory re

248 As) generated by Dicer presumably to prevent programming of the RNA-induced silencing complex (RISC).

249 loying the underlying database structure and programming of the Saccharomyces Genome Database, the Te

250 o RNA interference in eukaryotes) and the re-programming of the system to silence specific genes of i

251 e nucleotides (p)ppGpp, causing a massive re-programming of the transcriptional profile known as the

252 529 529 References 529 Re-programming of the transcriptome involves both transcrip

253 Re-programming of the transcriptome involves both transcrip

254 s under DD conditions revealed that rhythmic programming of the transcriptome is dependent on an inte

255 p-flow intervals and independent temperature programming of the two columns, it is possible to adjust

256 ulture in vitro, this may reflect long-term "programming" of the fetal cardiovascular system.

257 fter experimental surgeries suggest that the programming of these characteristics follows similar rul

258 ells but are inadequate in inducing complete programming of this subset.

259 n, which is critical for sustaining temporal programming of tissue physiology.

260 oxp3 has a major role in the development and programming of Treg cells.

261 both necessary and sufficient to support the programming of TRM cell fate in tissue-infiltrating T ce

262 vestigated the developmental and nutritional programming of uncoupling protein-2 (UCP2), glucocortico

263 of the SWNT phase allow for fast temperature programming of up to 60 degrees C/s.

264 dverse intrauterine environment alters fetal programming of vascular reactivity in adult offspring.

265 Programming of ventricular tachyarrhythmia (ventricular