ライフサイエンスコーパス: proinflammatory

1 uction pathways, indicating it is not solely proinflammatory.

2 SCs can respond to tissue injury by anti- or proinflammatory activation.

3 ho are more socially isolated show increased proinflammatory activity in response to an inflammatory

4 that exposure to social stressors increases proinflammatory activity, (2) that individuals who are m

5 ocially isolated (ie, lonely) show increased proinflammatory activity, and (3) that individuals who a

6 ) immune cells in SHRs represent an abnormal proinflammatory adaptive immune response.

7 vitro, as characterized by secretion of both proinflammatory and anti-inflammatory cytokines from mur

8 Eight proinflammatory and anti-inflammatory cytokines were mea

9 Because these functions differ in proinflammatory and anti-inflammatory macrophages, we co

10 t manner, and is required for induction of a proinflammatory and antifungal response.

11 We detected TLR2-, TLR4-, and C5aR-mediated proinflammatory and fibrotic responses to bacteria that

12 n conclusion, CD8(+)RORgammat(+) T cells are proinflammatory and functionally impaired and may contri

13 Interleukin-6 is a cytokine critical to proinflammatory and immune regulatory cascades.

14 integrin alphaMbeta2 (CR3 or Mac-1) has both proinflammatory and immune regulatory functions.

15 nd other inflammation agonists as well as 14 proinflammatory and nine anti-inflammatory eicosanoids w

16 hese molecules on attachment, migration, and proinflammatory and prodestructive activation of RASFs w

17 rophages) and decreased expression levels of proinflammatory and profibrotic markers that were indepe

18 potential for RORgammat-driven expression of proinflammatory and prohypertensive IL-17F in response t

19 pathways leading to abundance shifts between proinflammatory and proresolving lipid mediators provide

20 hoinositol inhibits the de novo synthesis of proinflammatory and prothrombotic compounds and might th

21 Macrophages are a source of both proinflammatory and restorative functions in damaged tis

22 They respond with production of proinflammatory and TH17-skewing cytokines, resulting in

23 n of mechanistic target of rapamycin (mTOR), proinflammatory, and anti-apoptotic signaling pathways,

24 Fc receptors is required for the control of proinflammatory, anti-inflammatory, and immunomodulatory

25 ting that cdN inhibition of RECON promotes a proinflammatory, antibacterial state that is distinct fr

26 exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent endothelial ph

27 on caused by vasoactive peptide thrombin and proinflammatory bacterial wall lipopolysaccharide (LPS).

28 Expression of proinflammatory biomarkers, including interleukin (IL) 1

29 gated whether BCA2 is also connected to this proinflammatory cascade.

30 ACKR2) binds, internalizes and degrades most proinflammatory CC-chemokines.

31 erosclerosis by promoting the maintenance of proinflammatory CD11c(+) macrophages within lesions and

32 BOS is associated with increased cytotoxic/proinflammatory CD8+ T, NKT-like, and NK cells in the sm

33 We hypothesized that proinflammatory cell death such as necrosis would be pro

34 and RIP3 pathways together to suppress this proinflammatory cell death.

35 uppressive function is lost in patients upon proinflammatory challenge; protracted modulation of the

36 ated the inhibitory effect of adiponectin on proinflammatory change.

37 proximal colon cancer risk was higher in the proinflammatory-change DII group than in the antiinflamm

38 acrophage infiltration and expression of the proinflammatory chemokine MCP-1.

39 CXCL5 is classically defined as a proinflammatory chemokine, but its role in chronic infla

40 ATP mediated gene induction of CXCL5, a proinflammatory chemokine.

41 pproaches to show increased infiltration and proinflammatory (classically activated [M1]) polarizatio

42 We found that, under proinflammatory conditions, microRNA-146a (miR-146a) is

43 -M, also known as IRAK-3, is an inhibitor of proinflammatory cytokine and chemokine expression in int

44 IFNs but were associated with altered local proinflammatory cytokine and chemokine responses and dif

45 Siglec-E16 enhanced proinflammatory cytokine expression and bacterial killin

46 In addition, tapinarof moderates proinflammatory cytokine expression in stimulated periph

47 ion proteins, myosin light chain kinase, and proinflammatory cytokine expression.

48 nza virus-induced lethality and reduced both proinflammatory cytokine gene expression in the lungs an

49 nonrelevant modifications of the prototypic proinflammatory cytokine IL-1beta during an immune respo

50 ated the canonical NF-kappaB pathway and the proinflammatory cytokine IL-6 in autoantibody production

51 At 6 h we detect the proinflammatory cytokine IL-6 in the hippocampus, follow

52 IL-34 is a proinflammatory cytokine implicated in rheumatoid arthri

53 The proinflammatory cytokine interferon-gamma-induced protei

54 Increased level of proinflammatory cytokine interleukin (IL)-12 correlates

55 Basal tear levels of the proinflammatory cytokine interleukin 17A were significan

56 at wild type mice had significantly elevated proinflammatory cytokine levels, reduced ejection fracti

57 The elevated levels of this proinflammatory cytokine may explain the increased incid

58 r (NF)-kappaB, which induced expression of a proinflammatory cytokine module that, along with the ant

59 Proinflammatory cytokine overproduction and excessive ce

60 ng trauma but displayed decreased stimulated proinflammatory cytokine production and significantly re

61 d survival, attenuated hypothermia, and less proinflammatory cytokine production during septic shock

62 RGS10 has emerged as a key regulator of proinflammatory cytokine production in microglia, functi

63 ent mice indicated that Acanthamoeba-induced proinflammatory cytokine production was through MyD88-de

64 ells promotes enhanced T cell activation and proinflammatory cytokine production.

65 ted with GC storage, tissue inflammation and proinflammatory cytokine production.

66 duced NF-kappaB translocation and downstream proinflammatory cytokine production.

67 This was accompanied by an exaggerated proinflammatory cytokine profile and increased STAT3 sig

68 Proinflammatory cytokine release was determined after 2,

69 , and expansion of blood monocytes with less proinflammatory cytokine response to bacterial stimulati

70 a serovar Typhimurium-induced pyroptosis and proinflammatory cytokine secretion in macrophages.

71 e degrading desmosomal proteins and inducing proinflammatory cytokine secretion through protease-acti

72 IL-6 is a pleiotropic proinflammatory cytokine that is elevated in serum and s

73 In this work, we titered bacteria and/or the proinflammatory cytokine TNFalpha in a set of establishe

74 utes to their extraordinary vulnerability to proinflammatory cytokine toxicity and may therefore repr

75 microglia in the ARC, the expression of the proinflammatory cytokine tumor necrosis factor-alpha in

76 ation inhibitory factor (MIF), a pleiotropic proinflammatory cytokine, in this process.

77 Interleukin-1 (IL-1), an important proinflammatory cytokine, is suspected to play a role in

78 n of the thymic stromal lymphopoietin (TSLP) proinflammatory cytokine.

79 tion of inflammation, including reduction of proinflammatory cytokines (CXCL1, CXCL2, CCL3, CCL4, IL6

80 phate nucleotidohydrolase induced SAMHD1 and proinflammatory cytokines (eg, interleukin 6, interleuki

81 r cytotoxic mediators (perforin/granzyme B), proinflammatory cytokines (IFNgamma/TNFalpha), and expre

82 species (ROS) and upregulated expression of proinflammatory cytokines (IL-1beta and TNFalpha).

83 C-treated hearts show enhanced production of proinflammatory cytokines (interleukin-3, interleukin-6,

84 An increase in proinflammatory cytokines (TNFalpha and KC/GRO) was obse

85 ndent gene expression and down-regulation of proinflammatory cytokines and adhesion molecules.

86 RA101295 abolished sepsis-induced surges in proinflammatory cytokines and attenuated systemic circul

87 stable proliferation arrest and secretion of proinflammatory cytokines and chemokines, the senescence

88 hereas MIA produced significant increases in proinflammatory cytokines and chemokines.

89 very to the lung downregulates expression of proinflammatory cytokines and improves allergen-induced

90 Activation of Nlrp3 leads to synthesis of proinflammatory cytokines and influences epithelial inte

91 hese macrophage-like nanoparticles sequester proinflammatory cytokines and inhibit their ability to p

92 of infection, WT mice had higher circulatory proinflammatory cytokines and lower anti-inflammatory cy

93 nogenesis, we evaluated associations between proinflammatory cytokines and lung cancer risk.

94 -cycle arrest combined with the secretion of proinflammatory cytokines and mitochondrial dysfunction.

95 duced sepsis, decreases the plasma levels of proinflammatory cytokines and organ injury markers in a

96 f atherosclerotic plaques, the production of proinflammatory cytokines and reactive oxygen species, t

97 glucocorticoid biosynthesis is suppressed by proinflammatory cytokines and that glucocorticoid defici

98 mulated insulin secretion in the presence of proinflammatory cytokines and triggered gene expression

99 tion, and leukocyte migration plus genes for proinflammatory cytokines and various toll-like receptor

100 mmation, accompanied by a massive release of proinflammatory cytokines at the maternal-fetal interfac

101 ens at various nonmucosal sites by eliciting proinflammatory cytokines by human macrophages, monocyte

102 these glycolipids induced the production of proinflammatory cytokines by macrophages, thereby sugges

103 While proinflammatory cytokines can be detected in the lungs a

104 Cholangiocytes secrete proinflammatory cytokines during bacterial infection lea

105 ungs and their relationship with circulating proinflammatory cytokines during ischemia-reperfusion in

106 m and hypothalamic mRNA responses of certain proinflammatory cytokines during the active phase.

107 The tumor microenvironment supplies proinflammatory cytokines favoring a permissive milieu f

108 o, these dendrimers reduced the secretion of proinflammatory cytokines from mice and human monocyte-d

109 le for caspase-1-dependent maturation of the proinflammatory cytokines IL-1beta and IL-18.

110 ults in caspase-1-dependent secretion of the proinflammatory cytokines IL-1beta and IL-18.

111 R4 activation to limit the production of the proinflammatory cytokines IL-6 and IL-12p40 while enhanc

112 The mRNA and protein expression levels of proinflammatory cytokines IL6, IL8 and CCL5 were determi

113 In vivo neutralization of these proinflammatory cytokines impaired bacterial clearance a

114 ased survival rates and heightened levels of proinflammatory cytokines in both peritoneal lavage and

115 he reduced capacity of leukocytes to release proinflammatory cytokines in response to ex vivo stimula

116 ound that Ndfip1 restricts production of the proinflammatory cytokines in Th17 cells.

117 d mononuclear cells (MMCs) and the levels of proinflammatory cytokines in the blood and the brains of

118 , and quantitative RT-PCR (qRT-PCR), and the proinflammatory cytokines interleukin 1beta, interferon

119 dent subjects compared with controls for the proinflammatory cytokines interleukin-6 and interleukin-

120 xtra-respiratory organs in the production of proinflammatory cytokines is unknown.

121 iologics are currently available that target proinflammatory cytokines produced by T lymphocytes, but

122 cer cells in vitro induced the expression of proinflammatory cytokines such as CXCL5 by activating St

123 h covR-deficient S. agalactiae produced less proinflammatory cytokines than those infected with wild-

124 nalysis of human macrophages showed that the proinflammatory cytokines TNF and type I interferons ind

125 atory protein cyclooxygenase (COX)-2 and the proinflammatory cytokines TNF-alpha, IL-6, and IL-12.

126 ults together suggest that NRTIs up-regulate proinflammatory cytokines via a Wnt5a signaling-dependen

127 s significant inhibition in the synthesis of proinflammatory cytokines with a concordant blockade of

128 T2D, and these cells are the main source of proinflammatory cytokines within islets.

129 (less cardiac infiltrates and suppression of proinflammatory cytokines), cardiac fibrosis, apoptosis,

130 binding to TLR2 induced robust expression of proinflammatory cytokines, and end products of lipid oxi

131 traumatic insult), become activated, produce proinflammatory cytokines, and recruit monocytes and den

132 inflammatory cells with local production of proinflammatory cytokines, and subsequent epithelial dis

133 on of TNF-alpha and IL-1beta, widely studied proinflammatory cytokines, did not induce persistent dis

134 phages results in the coordinated release of proinflammatory cytokines, followed by regulatory mediat

135 Proinflammatory cytokines, IFN-gamma and IL-17A, produce

136 , P2X7R activation induces the production of proinflammatory cytokines, including IL-1beta and IL-18,

137 the dysregulation of osteoclast activity by proinflammatory cytokines, including TNF, interferes wit

138 tivation characterized by elevated levels of proinflammatory cytokines, including type I interferons

139 with pH1N1/NSs-6mut induced lower levels of proinflammatory cytokines, likely due to a general inhib

140 ges (pH1N1/NSs-6mut) induced lower levels of proinflammatory cytokines, resulting in viral attenuatio

141 gnificantly higher expression and release of proinflammatory cytokines, such as chemokine (C-C motif)

142 +) monocytes, as well as increased levels of proinflammatory cytokines, such as TNF-alpha and IL-17.

143 ading to cell type-specific amplification of proinflammatory cytokines, such as TNF-alpha, IL-1beta,

144 Kal directly activated monocytes to produce proinflammatory cytokines, up-regulated their C5aR and F

145 in Ld-infected cells curtails production of proinflammatory cytokines, which are otherwise detriment

146 itantly, S. aureus elicits the production of proinflammatory cytokines, which could ultimately pertur

147 nt expression of type I interferon and other proinflammatory cytokines.

148 in increased production of type 2 and other proinflammatory cytokines.

149 ncluding Kupffer cells exposed to HCV induce proinflammatory cytokines.

150 signaling pathways leading to the release of proinflammatory cytokines.

151 K signalling and increases the production of proinflammatory cytokines.

152 d profound uveal inflammation and release of proinflammatory cytokines.

153 related with enhanced expression of numerous proinflammatory cytokines.

154 ecific T cell proliferation and secretion of proinflammatory cytokines.

155 the mechanisms behind its downregulation by proinflammatory cytokines.

156 ting levels of CXCL9, CXCL10, and downstream proinflammatory cytokines.

157 ases 1 (TIMP-1), downregulated expression of proinflammatory cytokines/chemokines, and significantly

158 on and open new therapeutic avenues to treat proinflammatory diseases.

159 The proinflammatory effect of MSU crystals was accompanied b

160 e identity of the ex-RNA responsible for the proinflammatory effect remains unclear.

161 novicida infection due to overproduction of proinflammatory effectors including prostaglandin E2.

162 and phthalates may have immunomodulatory and proinflammatory effects and thereby adversely affect res

163 The proinflammatory effects of MSU crystals were shown to be

164 nhibits both myometrial contractions and the proinflammatory effects of OT without the biased agonist

165 Gal-3 also exerts proinflammatory effects, at least in extracardiac tissue

166 P-microvesicle interactions, abrogates these proinflammatory effects.

167 s, membrane release of AA, and generation of proinflammatory eicosanoids and may account for increase

168 These results suggest Aa-induced proinflammatory endothelial responses are regulated by r

169 e models of WNV infection demonstrate that a proinflammatory environment is induced within the centra

170 ough ROS production is typically viewed as a proinflammatory event, our observations identify the imp

171 T cell accumulation, and high levels of the proinflammatory factors IFN-gamma, TNF-alpha, and induci

172 eport on a novel mechanism that promotes the proinflammatory function of PGE2 We showed previously th

173 In addition to its procoagulant and proinflammatory functions mediated by cleavage of fibrin

174 PR3 has a number of well-characterized proinflammatory functions, including cleaving and activa

175 inhibition of NEDDylation by MLN4924 blocked proinflammatory gene expression and NF-kappaB activation

176 n may represent a novel approach to modulate proinflammatory gene expression and open new therapeutic

177 c plaque formation, characterized by reduced proinflammatory gene expression and plaque macrophage co

178 meres were concordant with proosteoblast and proinflammatory gene network alterations in human NOTCH1

179 at HCMV induces the upregulation of multiple proinflammatory gene ontologies, with the interferon-ass

180 d with oxLDL, whereas the induction of other proinflammatory genes by TLR4 (LPS), TLR3 (polyriboinosi

181 ment containing mRNAs typically found within proinflammatory genes.

182 amin D3 levels had significant expression of proinflammatory genes.

183 We propose that disparate proinflammatory host signatures contribute to the differ

184 periodontitis progression is conditional on proinflammatory IL-1 genetic variations.

185 sponses in the lung, including activation of proinflammatory IL-17-producing gammadelta T cells, with

186 ammation associated with overt production of proinflammatory IL-1beta.

187 Proinflammatory immune mediators, lysophospholipids as w

188 as to determine the changes in expression of proinflammatory innate and T-cell-derived cytokines duri

189 ulated expression levels were found for most proinflammatory innate cytokines, including tumor necros

190 note was an increase in the abundance of the proinflammatory leukotriene B4 (LTB4) and a correspondin

191 Proinflammatory leukotrienes (LTs) are produced by 5-lip

192 okines that correlated with severity, 13 are proinflammatory, likely contributing to many of the symp

193 Leukotrienes are proinflammatory lipid mediators that have been shown to

194 e signature within the pancreas, and reduced proinflammatory M1 macrophage responses were observed.

195 se peritoneal and human macrophages toward a proinflammatory M1 phenotype.

196 ing heterogeneous phenotypes, from classical proinflammatory M1 to alternative anti-inflammatory M2 m

197 ting the expression of genes associated with proinflammatory (M1) macrophage activation and was prote

198 f macrophages from anti-inflammatory (M2) to proinflammatory (M1) subtype after incubation with MfP.

199 interference decreases markers of glomerular proinflammatory macrophage activation.

200 d revealed its predominant role in promoting proinflammatory macrophage functions.

201 Both Acanthamoeba strains induced a proinflammatory macrophage phenotype characterized by th

202 mediated by inflammatory monocytes (IM) and proinflammatory macrophages (M1), followed by polarizati

203 Activation of proinflammatory macrophages is associated with the infla

204 te recruitment (T lymphocytes and classic M1 proinflammatory macrophages) and decreased expression le

205 LPS-induced release of the proinflammatory marker tumor necrosis factor-alpha in bl

206 atment with 2-AG suppresses TNFalpha-induced proinflammatory markers and improves IR and glucose upta

207 ssociated with reduced NF-kappaB activation, proinflammatory markers, endoplasmic reticulum stress, a

208 , with improvement in vasculitic disease and proinflammatory markers.

209 on resolving) and granulocyte-M-CSF (GM-CSF; proinflammatory) may contribute to the inconsistency of

210 s on intestinal MCs indicated an increase in proinflammatory MC function in advanced stages of the di

211 Leukotriene B4 (LTB4), a proinflammatory mediator produced by the enzyme 5-lipoxy

212 functions such as neurotoxin, gliotoxin, and proinflammatory mediator, and it alters the integrity an

213 aride model of inflammation, RVX-297 reduced proinflammatory mediators assessed in splenic gene expre

214 bly was associated with reduced secretion of proinflammatory mediators from microglia cells, ultimate

215 popolysaccharide (LPS) significantly induced proinflammatory mediators in a dose-dependent manner.

216 ion, increased expression of profibrotic and proinflammatory mediators, and increased TRPC6, PKC-alph

217 s well as flow cytometry and measurements of proinflammatory mediators.

218 s and NF-kappaB and subsequent expression of proinflammatory mediators.

219 LRP1 gene silencing increases expression of proinflammatory mediators; however, the observed respons

220 inases of which p38alpha/MAPK14 is the major proinflammatory member.

221 bic exercise is feasible and can improve the proinflammatory metabolic milieu in patients with modera

222 nic back pain and is linked to production of proinflammatory molecules by nucleus pulposus (NP) and o

223 challenge, leading to enhanced production of proinflammatory molecules upon other subsequent, and tem

224 By secreting proinflammatory molecules, immune cells may induce myocy

225 s accompanied by increased expression of the proinflammatory molecules.

226 ation with increases in IL-23 and IL-17A and proinflammatory monocytosis and neutrophilia that preced

227 which was associated with a high density of proinflammatory MPs.

228 in processing complex involved in regulating proinflammatory mRNA expression in the heart.

229 ) has been identified as a critical brake on proinflammatory nuclear factor kappa light chain enhance

230 program in tumor-associated macrophages to a proinflammatory one, with a concomitant reduction of the

231 In addition to hypercholesterolemia, the proinflammatory Paigen diet significantly increased VCAM

232 ls promote the asthma phenotype and that the proinflammatory pathway downstream of the beta2AR involv

233 rted for ebolavirus species and suggest that proinflammatory pathways represent an intriguing target

234 ives resident and transplanted MSCs toward a proinflammatory phenotype and restricts their survival a

235 which the highest tertile reflects the most proinflammatory potential of the diet.

236 ted that the epithelial barrier to bacterial proinflammatory products is impaired when biofilm lysine

237 ut changing the number of macrophages with a proinflammatory profile (M1 [F4/80(low) Gr1(+) CD11b(med

238 Metabololipidomics reveal a proinflammatory profile in diabetic serum.

239 d (monosodium urate [MSU]) crystals induce a proinflammatory profile in isolated human term cytotroph

240 , NFAT5 enhanced functions associated with a proinflammatory profile such as bactericidal capacity an

241 valuated in human tumor xenograft models the proinflammatory properties of an oncolytic adenovirus (O

242 While the proinflammatory properties of IL-17 are key to its host-

243 26 expressed in inflammatory lesions confers proinflammatory properties to DNA released by dying cell

244 as detected by the reduced induction of the proinflammatory protein cyclooxygenase (COX)-2 and the p

245 factor kappa B and reduced the expression of proinflammatory proteins (inducible nitric oxide synthas

246 mmation coincident with massive increases in proinflammatory proteins and IFN-alpha in distal airways

247 arginase 1, indicating that it could promote proinflammatory readiness by regulating independent gene

248 ly, prediction analysis showed inhibition of proinflammatory regulators and activation of anti-inflam

249 itotic origin, micronuclei formation and the proinflammatory response following DNA damage are cell-c

250 etermine whether rosuvastatin can reduce the proinflammatory response induced by Aggregatibacter acti

251 ncy in the pig and may serve to regulate the proinflammatory response of endometrium to IL1B2 during

252 /6 mice resist various pathogens through the proinflammatory response of their M1 macrophages (MPs).

253 summary, whereas TonEBP participates in the proinflammatory response to TNF-alpha, therapeutic strat

254 oxisomes blocked the TLR4 ligand LPS-induced proinflammatory response, as detected by the reduced ind

255 s expected, EBOV infection led to a profound proinflammatory response, including strong induction of

256 eutics that potentially limits a detrimental proinflammatory response.

257 itate conditions macrophages for exacerbated proinflammatory responses (lower IL-10 and CCL2, higher

258 However, the mechanisms involved in proinflammatory responses against GBS, as well as the co

259 3, which down-regulates T-helper cell type 1 proinflammatory responses and is associated with chronic

260 required for IL-1beta- or IL-1alpha-mediated proinflammatory responses and the stimulatory effects of

261 al IL18 haplotype associated with heightened proinflammatory responses confers susceptibility to stre

262 clude that T. suis secretes PGE2 to suppress proinflammatory responses in human DCs, thereby modulati

263 icus, both increased in MS patients, induced proinflammatory responses in human peripheral blood mono

264 acellular signaling pathways involved in the proinflammatory responses of macrophages are well charac

265 ating periodontopathogen-induced endothelial proinflammatory responses remains unclear.

266 portant for viral clearance, modify the host proinflammatory responses through effects on the inflamm

267 tein (pH1N1/NSs-6mut) inhibited host IFN and proinflammatory responses to a greater extent than that

268 Proinflammatory responses to GBS mediated through host i

269 d the role of protein kinase D (PKD)1 in the proinflammatory responses to GBS.

270 key immunoregulatory mediator and can dampen proinflammatory responses via activation of histamine re

271 gulatory network leading to the dampening of proinflammatory responses, expansion of type 1 regulator

272 ct of STING activation by DMXAA on enhancing proinflammatory responses.

273 vates Toll-like receptor 4 (TLR4) to trigger proinflammatory responses.

274 We aimed to provide an understanding of the proinflammatory role of bronchoalveolar lavage fluid (BA

275 In addition to its proinflammatory role, SP and its metabolites in combinat

276 We also inhibited the production of the proinflammatory secretome of senescent cells using a JAK

277 Nonetheless, BST2 may induce or amplify proinflammatory signaling during Ebola virus infection,

278 mmunity and implicate TLR-mediated NF-kappaB proinflammatory signaling from the late endocytic pathwa

279 responses to atherogenic diet by restraining proinflammatory signaling in endothelial cells and BM-de

280 herapeutic target for its ability to counter proinflammatory signaling.

281 nt response genes, and limited NF-kappaB and proinflammatory signaling.

282 tion of bioactive matrix fragments activates proinflammatory signaling.

283 y drugs (NSAIDs) (Pinteraction = 0.055), the proinflammatory-stable DII group was at increased risk o

284 by SAMs and shifts the SAM profile to a more proinflammatory state.

285 We hypothesized that systemic proinflammatory states and anti-inflammatory medications

286 In mouse models, TRX80 was associated with a proinflammatory status and increased atherosclerosis.

287 se benign effects of RSFC from an anti- to a proinflammatory status.

288 We found that proinflammatory stimulants LPS, IL-6 and IL-1beta up-reg

289 as a zinc transporter that is inducible via proinflammatory stimuli.

290 and sFRP5 was differentially regulated by a proinflammatory stimulus (lipopolysaccharide [LPS] from

291 Induction of proinflammatory T cell immunity is augmented by innate d

292 -associated kinase (ROCK)2 downregulates the proinflammatory T cell response while increasing the reg

293 stence via the same mechanism of controlling proinflammatory T cell responses.

294 2 infusion was associated with reduced donor proinflammatory Th1 and Th17 cells, accumulation of dono

295 gic mice SD favors immune responses toward a proinflammatory TH17 profile.

296 tions in the VEC monolayer were increased by proinflammatory thrombin treatment.

297 Finally, BNN27 reduced the proinflammatory (TNFalpha and IL-1beta) and increased th

298 and TBK1 signaling, triggering a switch from proinflammatory to anti-inflammatory responses.

299 itaconate in mice and contributes to a less proinflammatory transcriptome signature.

300 tion in myeloid cells restored activation of proinflammatory tumor-associated macrophages (TAM) and i