ライフサイエンスコーパス: proliferation

1 pha/Akt signaling, promoting cell growth and proliferation.

2 tant p53, significantly inhibited tumor cell proliferation.

3 ently reversed E1S- and E1-induced T47D cell proliferation.

4 , was a very effective compound induced SSCs proliferation.

5 for effects of CDK4/CDK6 inhibitors on cell proliferation.

6 chemokines and controlling cell survival and proliferation.

7 Teff cells, was required for selective Treg proliferation.

8 ular smooth muscle cell (VSMC) migration and proliferation.

9 and flow cytometry assays for apoptosis and proliferation.

10 together drove their suppression of TH2 cell proliferation.

11 ide, further enhancing stimulation of T-cell proliferation.

12 connected with human cancer development and proliferation.

13 ) play a critical role in cell signaling and proliferation.

14 ared to be compensated for by increased MPP4 proliferation.

15 lular differentiation to aggressive cellular proliferation.

16 proliferation, but did stimulate VDR KO cell proliferation.

17 ging metrics using (18)F-FLT to assess tumor proliferation.

18 ms by which these GFs regulate the survival, proliferation.

19 ellular functions, including metabolisms and proliferation.

20 nutrients required for continued growth and proliferation.

21 ilitate cell-cycle progression and stem cell proliferation.

22 sion of KLF5; a high level of KLF5 increased proliferation.

23 uencing compensatory signaling and expanding proliferation.

24 s that regulate cellular differentiation and proliferation.

25 associated with differentiation rather than proliferation.

26 ide led to reverse CD8+ T cell-enhanced BECs proliferation.

27 n cancer cells to promote their survival and proliferation.

28 lactate production and increased SHH-driven proliferation.

29 regulate cell migration, cell adhesion, and proliferation.

30 iron and an augmented dependence on iron for proliferation.

31 is one pathway that suppresses local T cell proliferation.

32 centration, hormone secretion/expression and proliferation.

33 lation over genes associated with progenitor proliferation.

34 itive and negative signals that control cell proliferation.

35 lts from altered cell cycle and reduced cell proliferation.

36 fferentiation and taste stem/progenitor cell proliferation.

37 ator of cell differentiation, migration, and proliferation.

38 ive regions, is dominated by microstructural proliferation.

39 tween organellar genome maintenance and cell proliferation.

40 lation, c-Myc up-regulation and reduced cell proliferation.

41 individual kinases in agonist-induced P-UAEC proliferation.

42 -2'-deoxyuridine to determine satellite cell proliferation, activation and fusion.

43 ed MNDCM content and increased cardiomyocyte proliferation after injury.

44 FN1, olaratumab specifically reduced HHSteC proliferation (AlamarBlue assay) and cell migration (tra

45 Vasculature proliferation also involves the cell cycle regulator KIP

46 imicked the effects of severe hypoxia on CPC proliferation, also triggering quiescence.

47 red to be due to blood infiltration or local proliferation, although the presence of resident hematop

48 s of expression led to a decrease in NB cell proliferation and 16 also induced differentiation.

49 moyl}amino)hexadecanoic acid (13b) decreased proliferation and activated apoptosis in MDA-MB-231 brea

50 Foxp1-Shq1 and Pten deletion show increased proliferation and anaplastic dedifferentiation, as well

51 gastric cancer cells leads to increased cell proliferation and angiogenesis, which may, in turn, cont

52 he expression of well characterized cellular proliferation and apoptosis guards (NF-kappaB, Bcl-2 and

53 e epithelial cell turnover and expression of proliferation and apoptosis-related genes in gastric can

54 ed dependence on IL-2 but unchanged rates of proliferation and apoptosis.

55 ntrols organ size by regulating cell growth, proliferation and apoptosis.

56 genes identified converge on aspects of cell proliferation and cell cycle regulation, including DNA s

57 lls with the equivalent human IFPs increased proliferation and cytokine production in response to CD2

58 HDV-specific T-cell proliferation and cytokine production were weak and coul

59 l processes such as autophagy, inflammation, proliferation and differentiation of stem cell, cell sur

60 expression, which is required for osteoblast proliferation and differentiation through transcriptiona

61 eling enzymes, is required for both myoblast proliferation and differentiation, and the control of Br

62 e a variety of cellular processes, including proliferation and differentiation.

63 on (TJ) proteins are known to be involved in proliferation and differentiation.

64 ling in order to reprogram naive T cells for proliferation and differentiation.

65 The three new AEs suppressed proliferation and estrogen target gene expression in WT

66 ate induced a time-dependent increase in LPC proliferation and expression of genes associated with ch

67 n to be involved in the regulation of T cell proliferation and function.

68 Expression of p53 and p21 was up-regulated; proliferation and G1/S cell-cycle transition slowed.

69 a cell, and is tightly linked to metabolism, proliferation and gene expression.

70 osis patients, mTORC1 activation, macrophage proliferation and glycolysis were identified as hallmark

71 o J774.2 macrophage cells, and supports cell proliferation and growth.

72 To determine factors leading to Mtb proliferation and host cell death, we used live cell ima

73 How caspases promote proliferation and how cells are protected from the poten

74 and delineated the relationship between cell proliferation and iCM induction.

75 ed by quantifying the dose-dependent drop in proliferation and increase in differentiation in etoposi

76 ne silencing of KIND1 decreased keratinocyte proliferation and increased apoptosis in vitro and in sk

77 TPO causes megakaryocyte proliferation and increased platelet production.

78 ought to identify cytokines that can promote proliferation and induce or maintain IL-22 production by

79 vivo exhibited the same temporal pattern of proliferation and infectious susceptibility.

80 Tnrc6a was previously reported to promote proliferation and inhibit differentiation of myoblast ce

81 The effects of PGE2 on human ILC2 proliferation and intracellular cytokine and transcripti

82 known molecular target of ABHD5, impeded the proliferation and invasion, suggesting an ATGL-independe

83 A4 (S100A4), a protein linked to cancer cell proliferation and invasiveness.

84 Organ growth and pancreatic islet cell proliferation and mass were examined in sheep fetuses fo

85 y assign therapies counteracting cancer cell proliferation and metastatic spread.

86 rapid cytoskeleton remodelling and inhibited proliferation and migration in VSMCs but not EC.

87 scavenged reactive oxygen species, inhibited proliferation and migration of smooth muscle cells (SMCs

88 To improve hCPC proliferation and migration responses that are critical

89 olysis, leading to impaired endothelial cell proliferation and migration.

90 Cell proliferation and neuroinflammation in the adult hypotha

91 results suggest that carbofuran inhibits NSC proliferation and neuronal differentiation by altering T

92 pIL6 ((IL6) WT LSCs) had significantly less proliferation and no tumorigenic properties.

93 noma (wdSCC), exhibiting p53 loss, increased proliferation and novel NF-kappaB expression.

94 cells caused JNK-mediated cholangiocellular proliferation and oncogenic transformation.

95 t Dengue virus (DENV)-NS2A, leads to reduced proliferation and premature differentiation of radial gl

96 d BRD7389, for their ability to inhibit both proliferation and protein synthesis in patient-derived m

97 The equilibrium between proliferation and quiescence of myogenic progenitor and

98 ction capacity, whereas AZA diminished their proliferation and reactivity.

99 ization, neutrophil clearance, cardiomyocyte proliferation and scar resolution.

100 e Hippo signaling pathway that regulate cell proliferation and stem cell functions.

101 rgy homeostasis to influencing hepatoma cell proliferation and suggest a potential role of SLC13A5 in

102 sizes during the early months, with reduced proliferation and suppression of AKT, S6, ERK, and STAT3

103 nd TAZ are required both to maintain TA cell proliferation and to inhibit differentiation.

104 ons within the ERK pathway can regulate cell proliferation and transformation, and suggest oncogene-s

105 an essential event for uncontrolled cellular proliferation and transformation.

106 l proliferative cells by inhibiting neuronal proliferation and triggering the formation of microglial

107 as OP9 preadipocytes were assessed for cell proliferation and triglyceride accumulation following di

108 Vgll4 inhibits cell proliferation and tumor growth by competing with YAP for

109 ription of downstream genes and promote cell proliferation and tumor growth in vivo Taken together, o

110 V infection yet are dispensable for cellular proliferation and viability.

111 exerts its effect on OPCs by inducing their proliferation and, at a late stage, by modulating OPC ma

112 han 10% naive T cells, reduced/absent T-cell proliferation, and at least 1 significant clinical event

113 cultures or in the SGZ induces increased NSC proliferation, and CD44-null as well as HA-disrupted wil

114 nse to Wnt stimuli and immunohistochemistry, proliferation, and cell death assays to identify new neu

115 ILC3 cytokine production, proliferation, and differentiation were determined by me

116 ctive cell behaviors such as cell migration, proliferation, and differentiation.

117 ore, low-dose DAC preserved HSPC-NK killing, proliferation, and interferon gamma production capacity,

118 bosome-related gene sets, promoted excessive proliferation, and led to retinoblastoma with anaplastic

119 -cycle-related genes are a characteristic of proliferation, and likely tumor evolution, rather than o

120 ctate levels strongly correlated with T cell proliferation, and measuring lactate compared favorably

121 m and progenitor cells displayed compromised proliferation, and replication stress that could be resc

122 healing, including hemostasis, inflammation, proliferation, and resolution/remodeling.

123 cer cell phenotypes, including angiogenesis, proliferation, and stemness, and a minor subpopulation (

124 erves as a molecular switch from invasion to proliferation, and suggest that targeting both receptors

125 ignaling to promote cell motility, invasion, proliferation, and survival.

126 gene body of DAPK3, a gene involved in cell proliferation, apoptosis, and autophagy.

127 NSF1), and functional effects on viability, proliferation, apoptosis, and cytotoxicity were monitore

128 r, the GLI2 targets that promote cancer cell proliferation are unknown.

129 cells underpin synovial hyperplasia through proliferation, are recruited to a Nestin-GFP(high) periv

130 The live/dead staining, cell proliferation assay and immunohistochemistry study of hu

131 Here, we performed marker analysis, cell proliferation assays, and genetic lineage tracing to def

132 ased expression levels of both FOXM1 and its proliferation-associated target genes.

133 estines, but caused no defects in epithelial proliferation, barrier integrity, or ultrastructure.

134 Knockdown had minimal effects on cell proliferation but blocked tumor cell invasion.

135 We found that platelets stimulated EOMA proliferation but did not mitigate apoptosis.

136 p3 activation had no effect on cholangiocyte proliferation but significantly decreased the expression

137 1,25(OH)2D3 did not affect WT cell proliferation, but did stimulate VDR KO cell proliferati

138 n stimulates and IMP2 elimination diminishes proliferation by 50-80%.

139 Blocking HFD-induced cell proliferation by central delivery of the antimitotic dru

140 gly, however, only LECs showed enhanced cell proliferation by regulating the vascular endothelial gro

141 triac) and 3-iodothyronamine (T1AM), on cell proliferation, cell death and DNA damage was studied in

142 ASXL3 silencing inhibited proliferation, clonogenicity, and teratoma formation by

143 ines that expressed MAN2A1-FER had increased proliferation, colony formation, and invasiveness and fo

144 median survival with reduced tumor size and proliferation compared with control Pten-mutant mice, th

145 Ag mice had an unexpected increase in villus proliferation compared with unmanipulated littermates, w

146 biting unique changes in pathways related to proliferation, cytoskeletal organization, and apoptosis.

147 In this report, we demonstrate enhanced proliferation, decreased apoptosis and increased cytotox

148 , CDK20-depleted cells display impaired cell proliferation, defective G2/M arrest and increased radio

149 Notably, proliferation defects were rescued upon the reexpression

150 This response is cell type- rather than proliferation-dependent and does not appear to be driven

151 sion analysis revealed a major defect in the proliferation, differentiation and mineralization abilit

152 dies showing its involvement in keratinocyte proliferation, differentiation, and migration and in epi

153 -related processes by controlling a neuronal proliferation/differentiation switch of ID-bHLH factors.

154 ase in APC function for allergen-specific TC proliferation during allergic inflammation is largely du

155 two independent systems to impair hepatocyte proliferation during liver injury to evaluate the contri

156 olved in regulating uterine endothelial cell proliferation during pregnancy.

157 late vascular branching and endothelial cell proliferation during retinal angiogenesis.

158 ]thymidine incorporation and the use of cell proliferation dyes).

159 cancer model systems, was required for cell proliferation, enhanced AR's transcriptional activity, a

160 Oncogenic Ras causes proliferation followed by premature senescence in primar

161 Upon injury, stem cells increase proliferation, followed by lineage differentiation to re

162 complex preferentially interacted with anti-proliferation gene transcripts in a Cnot3-dependent mann

163 were associated with unrestrained fibroblast proliferation, impaired scar remodeling, reduced fibrobl

164 ll tumours, caused a significant decrease in proliferation in 5/23 (22%) tumours, and that KRAS/BRAF

165 posure affected C. elegans survival and hMSC proliferation in a dose-dependent manner.

166 r homeostatic conditions was low, microglial proliferation in a mouse model of Alzheimer's beta-amylo

167 Gedatolisib also inhibited ALL proliferation in ABL/platelet-derived growth factor rece

168 sides, all compounds inhibit the trophozoite proliferation in amoebic liver abscess induced in hamste

169 e calcitriol treatment did not decrease cell proliferation in BVE(Cyp24a1-null) cells, it strengthene

170 ng after ligand exposure selectively delayed proliferation in cells with internalized TCRs.

171 low concentrations of 20E support prolonged proliferation in explanted wing discs in the absence of

172 ression moderately promotes self-renewal and proliferation in GSCs.

173 It significantly inhibited the proliferation in HEY, A2780, and A2780/Taxol cells as ev

174 factors resident in PML-NBs to promote their proliferation in host cells.

175 show that USP36 down-regulation alters cell proliferation in human cancer cells by inducing both apo

176 vates a second ARK, Ssp2/AMPKalpha, for cell proliferation in low environmental glucose.

177 athway effector Yap to inhibit cardiomyocyte proliferation in mice.

178 P2 deletion in mouse skin results in reduced proliferation in neonatal and wounded adult epidermis.

179 llows cells to manage this energy stress for proliferation in new osmotic states.

180 thelial cells (ECs) coordinate migration and proliferation in response to growth factor activation to

181 omosome segregation, p53 regulation and cell proliferation in somatic cells, but its role in embryoni

182 we do not find evidence implicating altered proliferation in the rescue, we observe a significant in

183 ce lacking CD44 demonstrate increases in NSC proliferation in the SGZ.

184 found no significant change in prostate cell proliferation in treated mice when compared to controls.

185 suppression results in a modest reduction of proliferation in vascular smooth muscle cells, but given

186 Finally, we show that CCAR2 is required for proliferation in vitro and in established SCC tumors in

187 icantly abolished platelet-induced EOMA cell proliferation in vitro and tumor development in vivo.

188 , EPO directly inhibited conventional T cell proliferation in vitro via tyrosine phosphatase SHP-1-de

189 sCD83 inhibits T cell proliferation in vitro, supports allograft survival in v

190 ificantly inhibited ductal branching and MEC proliferation in vivo, which corroborated the in vitro a

191 -dependent activation of gene expression and proliferation, in the absence of ligand or presence of 4

192 suffering from recurrent EBV-induced B cell proliferations including Hodgkin's lymphoma because of a

193 mice, intestinal epithelial permeability and proliferation increase; this led to the concept that gli

194 ntiated], respectively), chromogranin A, and proliferation index (Ki-67).

195 MAPKs signalling pathways facilitate P-UAEC proliferation induced by all of these hormones.

196 "A proliferation-inducing ligand" (APRIL) is a natural high

197 o the synergistic induction of apoptosis and proliferation inhibition in AML cell lines.

198 tive tissues, providing evidence of how cell proliferation is controlled in an identity-specific mann

199 Cell proliferation is essential to rapid tissue growth and re

200 the embryonal theory for cancer cell growth/proliferation is overly simplistic, as meiotic factors a

201 y how villus cell migration is affected when proliferation is perturbed.

202 Although this mode of proliferation is widespread in diverse bacterial lineage

203 cle, we show that CXCL8 expression, prior to proliferation, is common in newly arising T cells (so-ca

204 n of new taste bud cells, but not progenitor proliferation, is interrupted in mice treated with a hed

205 brate ribonuclease, is known to promote cell proliferation, leading to neovascularization as well as

206 survival times) were processed for DCX, cell proliferation markers (Ki-67, BrdU), pallial/subpallial

207 - and catecholamine-induced endothelial cell proliferation may be indicative of unappreciated evoluti

208 t and maturation and by suppressing aberrant proliferation mediated by the T cell antigen receptor (T

209 IL-5 increased proliferation, migration and colony tube formation in HU

210 and lung) significantly promote cancer cell proliferation, migration and invasion.

211 the signals inside the cells regulating cell proliferation, migration and survival.

212 onstrated that RGC32 overexpression promoted proliferation, migration and tumorigenic growth of human

213 s is known to alter cell behaviors including proliferation, migration, and cell-cell adhesion, which

214 lays diverse roles in the regulation of cell proliferation, migration, and differentiation, these dat

215 It mediates effects such as cell proliferation, migration, and differentiation.

216 and 24R,25(OH)2D3 on corneal epithelial cell proliferation, migration, and on the vitamin D activatin

217 L-deficient (lal(-/-)) mice possess enhanced proliferation, migration, and permeability of inflammato

218 elanoma tumor models decreased the levels of proliferation more than pancreatic cancer derived MDSC.

219 e inflammatory signals generated by aberrant proliferation, necrosis, and hypoxia.

220 complete Foxc1 loss leads to aberrations in proliferation, neuronal differentiation and migration in

221 tial for motor function, and uncontrolled SC proliferation occurs in cancer.

222 en-dependent signals delivered in the LZ, DZ proliferation occurs in the absence of such signals.

223 ic T cells are important to control HSV, and proliferation of activated T cells requires increased me

224 r MDS/EVI in regulating the formation and/or proliferation of adult intestinal adult stem cells durin

225 o inform on/off treatment cycles, suppresses proliferation of androgen-independent cells and lowers c

226 Continuous proliferation of atypical melanocytes was found in 21 (8

227 The vast, uncoordinated proliferation of bioinformatics resources (databases, so

228 n active role in regulating the survival and proliferation of cancer cells.

229 Assessing proliferation of CD3- and B220-postive lymphocytes by do

230 3 and CFB expression inhibited migration and proliferation of cSCC cells and resulted in potent inhib

231 ficient to blunt in vitro tube formation and proliferation of endothelial cells.

232 hese data suggest that zinc may inhibit cell proliferation of esophageal cancer cells through Orai1-m

233 s from the final polymeric coating increased proliferation of estrogen-sensitive MCF7 cells.

234 of STN NMDA receptors, which also suppresses proliferation of GABAergic pallido-STN inputs in PD mice

235 novel SOCE/Ca(2+)/beta-catenin-mediated anti-proliferation of GC cells, which is different from the c

236 irus-specific B cell responses by inhibiting proliferation of germinal center (GC) B cells.

237 ciated with reduced liver injury, diminished proliferation of hepatocytes and leukocytes, and attenua

238 Thus, the proliferation of HIV-1-infected cells may play a role in

239 th an ILC3 survival factor, IL-15, to induce proliferation of human ILC3s, as well as induce and main

240 brafish synergizes with MYCN to increase the proliferation of hyperplastic sympathoadrenal precursor

241 ike protein family (CLPs) able to induce the proliferation of imaginal disc cells in vitro.

242 osed mice treated with celecoxib reduced the proliferation of LLC1 naive cells, while the opposite oc

243 te endothelial-to-mesenchymal transition and proliferation of mesenchymal cells.

244 VEGF-A stimulated proliferation of MM cells in monolayer and in 3D sponges

245 ompartment and how wild-type cells limit the proliferation of mutant cells to maintain proper tissue

246 importance of these diseases as well as the proliferation of new diseases on a wider host range is l

247 he Forkhead family that is required for cell proliferation of normal cells.

248 resent antigen was examined by assessment of proliferation of ovalbumin-specific T cells in rat insul

249 growth factor, PDGF-AA, results in increased proliferation of PDGFRalpha+ cells via PI3K/Akt signalin

250 form the progenitor cell niche, and abnormal proliferation of progenitor cells.

251 While proliferation of resident neocortical microglia under ho

252 Pathological proliferation of retinal blood vessels commonly causes v

253 rated a synergistic decrease in the cellular proliferation of several ATC cells.

254 e assembly is essential for the survival and proliferation of SMARCA4/BRG1 mutant but not of SMARCA4/

255 mice induced endogenous CcnE1 expression and proliferation of surviving hepatocytes and nonparenchyma

256 ed that EBI3 activates STAT3 and induces the proliferation of the IL-6-dependent B9 mouse plasmacytom

257 wn, associated with a more extensive area of proliferation of the neighboring root mesenchyme.

258 instead a crucial role for SHH in promoting proliferation of these RP progenitors and for differenti

259 n of sensors of apoptotic cells impaired the proliferation of tissue-resident macrophages and the ind

260 In vitro, hSef-b inhibited proliferation of TRAMP C2 cells and attenuated activatio

261 essed the Hh-dependent growth events and the proliferation of tumor cells with aberrant activation of

262 Lymphomas represent clonal proliferations of lymphocytes that are broadly classifie

263 ures and assigned them to categories such as proliferation-progenitor, proliferation-transforming gro

264 Rapid cancer cell proliferation promotes the production of reducing equiva

265 ll intrinsic MyD88 signaling is required for proliferation, protection from apoptosis and expression

266 that I-PTH plays a critical role in cellular proliferation, proteoglycan distribution, and mineraliza

267 staining in human organ-cultured corneas and proliferation rate in cultured corneal epithelial cells.

268 Alamar blue assay was performed to check the proliferation rate of the cells.

269 n of ACTRT1 reduced the in vitro and in vivo proliferation rates of cell lines with aberrant activati

270 d jaw bones of Cdc73(+/-) mice had increased proliferation rates that were 2-fold higher than in Cdc7

271 is required for fueling B cells prior to DZ proliferation rather than for allowing cell-cycle progre

272 12 to 18 mg/L, significantly inhibited cell proliferation, reduced cell viability, and was directly

273 e 2 identified SAMD9L mutants decreased cell proliferation relative to wild-type protein.

274 sis precipitates AAA formation, whereas VSMC proliferation repairs the vessel wall.

275 (PH3) staining to assess apoptosis and cell proliferation, respectively, showed a significant increa

276 ith CMV antigens, induce a recall CD4(+) TH1 proliferation response only in CMV-seropositive donors.

277 Cas9 gene editing resulted in a halt of cell proliferation, severely impaired EGFR signaling and the

278 creased autophagy and decreased the aberrant proliferation signaling caused by mutant p53.

279 Overall, proliferation subclasses are associated with a more aggr

280 pression of various proteins involved in the proliferation, survival, migration and epithelial-to-mes

281 mutant models more effectively inhibited ALL proliferation than either inhibitor alone (P < .001) and

282 ependent energy signals alone stimulate cell proliferation, the development of a normal leaf lamina r

283 ector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic features of regula

284 interaction could potentially suppress virus proliferation, this approach could offer a new strategy

285 S treatment significantly decreased PCa cell proliferation through down-regulation of GR and up-regul

286 uperoxide and inhibited cyst epithelial cell proliferation through extracellular signal-related kinas

287 Cancer cells exploit Spy1 to stimulate proliferation through inappropriate activation of Cdks,

288 by increasing apoptosis and decreasing cell proliferation through initiation of cell cycle arrest.

289 categories such as proliferation-progenitor, proliferation-transforming growth factor beta, and Wnt-c

290 samples and positively correlated with cell proliferation, tumor grade and malignancy.

291 found that a PKA inhibitor impaired ES cell proliferation, tumor growth and metastasis, which was re

292 itro and in vivo by inhibiting leukemia cell proliferation/viability and by promoting cell-cycle arre

293 ith unmanipulated littermates, whereas crypt proliferation was decreased.

294 fic peripheral blood mononuclear cell (PBMC) proliferation was evident, while decreased mitogen-stimu

295 Cell proliferation was examined in ITPR2-knockout HepG2 cells

296 and its effect on early attachment rates and proliferation was studied on forty-eight corneas.

297 oli cells prevents Kras (G12D) -induced cell proliferation, which leads to reduced tumor formation.

298 ssion level is critical for lung cancer cell proliferation, which may serve as a prognostic marker fo

299 f infiltrating T cells and B cells underwent proliferation within the pituitary parenchyma.

300 e concentration-dependent inhibition of cell proliferation, yielding an IC50 value of 356 +/- 21 nM i