ライフサイエンスコーパス: proliferative capacity

1 th KIR2DS2(-) NK cells, independent of their proliferative capacity.

2 ry-associated polyfunctionality and enhanced proliferative capacity.

3 lls also had different memory phenotypes and proliferative capacity.

4 y, allowing analyses of their clonogenic and proliferative capacity.

5 es, and their entire T cell pool had reduced proliferative capacity.

6 d from the cell cycle and lost most of their proliferative capacity.

7 in IESCs, we observe significantly increased proliferative capacity.

8 functions in cancer cells might limit their proliferative capacity.

9 arker, suggesting that cells have lost their proliferative capacity.

10 s evidenced by higher cytokine secretion and proliferative capacity.

11 thro-megakaryocytic precursors with enhanced proliferative capacity.

12 scent cells with longer telomeres and higher proliferative capacity.

13 uppression may be inversely related to their proliferative capacity.

14 tention of CD34(+) progenitors with enhanced proliferative capacity.

15 effects of canonical Wnt signaling on their proliferative capacity.

16 ssociated with cancer, a disease of enhanced proliferative capacity.

17 s (HCECs) and contributes to their decreased proliferative capacity.

18 The product was only noted in cells with low proliferative capacity.

19 videnced by increased cytokine secretion and proliferative capacity.

20 ction of SM-myosin heavy chain and increased proliferative capacity.

21 d cell population capable of retaining their proliferative capacity.

22 69- and CD154-expressing T cells with higher proliferative capacity.

23 merous multifunctional CD4(+) Th1 cells with proliferative capacity.

24 Cs may have reached a physiologic plateau in proliferative capacity.

25 ction of side population cells with enhanced proliferative capacity.

26 chemia and reperfusion demonstrated enhanced proliferative capacity.

27 f two properties: pluripotency and unlimited proliferative capacity.

28 an important role in the regulation of their proliferative capacity.

29 idence of thymopoiesis, and sustained T-cell proliferative capacity.

30 wann cells display a transient diminution of proliferative capacity.

31 y can always acquire mutations that increase proliferative capacity.

32 Functionally, AD cells gained transient proliferative capacity.

33 ead to a long-lived memory state with potent proliferative capacity.

34 compared with blood, suggesting a diminished proliferative capacity.

35 t in integrin beta5 have lower migration and proliferative capacities.

36 n protein production and increase the cell's proliferative capacities.

37 dissimilar morphologies and self-renewal and proliferative capacities.

38 vascular smooth muscle cells, but given low proliferative capacity, a significant effect of the vari

39 ove through the oncogenic process of gaining proliferative capacity, acquiring angiogenic, invasive,

40 f the heart muscle, lose nearly all of their proliferative capacity after birth, limiting the heart's

41 dramatically increased survival and improved proliferative capacity after irradiation in vitro.

42 m Utox+ meth users had a significantly lower proliferative capacity after stimulation with a number o

43 ction of ribosomes and a failure to maintain proliferative capacity after stimulation.

44 oil was tested for its cytotoxicity and anti-proliferative capacity against LoVo and HepG2 cancer cel

45 ing aging despite heterogenous reductions in proliferative capacity, allowing aged muscle to mount a

46 gest that most ganglionic cells retain their proliferative capacities and postpone differentiation.

47 llus organoid cultures revealed an increased proliferative capacity and a lowered cyclooxygenase 2 (C

48 y competent, demonstrating a normal in vitro proliferative capacity and a preserved ability to produc

49 SMCs from elderly persons have limited proliferative capacity and a reduction in collagen produ

50 nduced a multifunctional CD4 population with proliferative capacity and ability to secrete interleuki

51 that are already characterized by increased proliferative capacity and aggressive tumorigenic phenot

52 f the c-myb gene leads to a slightly reduced proliferative capacity and an aberrant and accelerated d

53 have decreased migratory prowess and reduced proliferative capacity and an altered cytokine/growth fa

54 CQL4 in BLM-deficient cells leads to reduced proliferative capacity and an increased frequency of sis

55 IC)-infected melanocytes displayed increased proliferative capacity and biological features more remi

56 ant contributor to sarcoidosis CD4(+) T-cell proliferative capacity and clinical outcome.

57 finite lifespan in culture that limits their proliferative capacity and clinical use.

58 Their proliferative capacity and cytokine production (IFN-gamm

59 ed tumor-infiltrating Tregs and restores the proliferative capacity and cytokine production of CD4+CD

60 epitope-specific T cells displayed enhanced proliferative capacity and delayed cytokine kinetics.

61 uration of these interactions may affect the proliferative capacity and differentiation of the activa

62 E also contains Sox2(+) cells with sustained proliferative capacity and disrupted pituitary different

63 ficient, terminally mature NK cells retained proliferative capacity and exhibited heightened reconsti

64 AT1-deficient CD4(+) T cells maintain higher proliferative capacity and expression of effector cytoki

65 asp2(-/-) tumor cells displayed an increased proliferative capacity and extensive aneuploidy that coi

66 mbryonic stem cells (ESCs) have an unlimited proliferative capacity and extensive differentiation cap

67 Neutrophils are deprived of proliferative capacity and have a tightly controlled lif

68 ine-mediated priming phase, and enhanced the proliferative capacity and hepatic regeneration ratio in

69 ific CD4(+)CD25(+)FoxP3(-) T cells with high proliferative capacity and IFN-gamma production, indicat

70 ng immune function in NOD2(-/-) mice, T cell proliferative capacity and IL-2 production were not impa

71 ure to activate Treg telomerase may restrict proliferative capacity and increase apoptotic susceptibi

72 h together programmed their robust secondary proliferative capacity and interferon-gamma (IFN-gamma)-

73 trated that MSCs in ITP patients had reduced proliferative capacity and lost their immunosuppressive

74 ellular state of the NSC by preserving their proliferative capacity and modulating their cell cycle p

75 populations, these lymphocytes had increased proliferative capacity and more efficiently reconstitute

76 e-cell sequencing, directly demonstrated the proliferative capacity and multipotency of this populati

77 of postnatal blood vessels, possessing high proliferative capacity and potential to generate endothe

78 are endothelial precursor cells with a high proliferative capacity and pro-angiogenic potential.

79 lymphoid organ Tregs had significant ex vivo proliferative capacity and produced cytokines like inter

80 egulator of ILC2 bioenergetics that controls proliferative capacity and proinflammatory functions pro

81 ed insulin secretion can result from reduced proliferative capacity and reduced islet function.

82 ho kinase inhibitor, greatly increased their proliferative capacity and resulted in efficient immorta

83 a common effector pathway that promotes the proliferative capacity and self-renewal potential of mye

84 ICAM-1(null) T cells also showed reduced proliferative capacity and substantially reduced levels

85 e marrow progenitor cells leads to increased proliferative capacity and survival, as well as a partia

86 sociated with CD27 downregulation, retaining proliferative capacity and TCR sensitivity, displaying i

87 We assessed proliferative capacity and telomere length using flow-fl

88 6 is the primary determinant of the NHP cell proliferative capacity and that hTERT is required for un

89 intenance of HSCs by directly reducing their proliferative capacity and that IFN-gamma impairs restor

90 in epithelial cells with high clonogenic and proliferative capacity and that stem cells lacking p63 u

91 genitor cells, which were required to retain proliferative capacity and to prevent premature differen

92 ck-in megakaryocyte progenitors have reduced proliferative capacity and undergo increased cell death,

93 n Abi3bp shRNA construct, displayed a higher proliferative capacity and, under differentiating condit

94 activity, p16, and p53 expression and lower proliferative capacity), and an increased PGE2, IL-6, IL

95 e fact that cancer cells are known for their proliferative capacity, and adult cardiomyocytes are, ex

96 a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequent

97 exhibits markedly altered cytoarchitecture, proliferative capacity, and degree of cell death.

98 of chemokine receptors, display differential proliferative capacity, and exhibit a higher level of ma

99 ells take on a glial-like morphology, retain proliferative capacity, and express glial markers and be

100 ion of reactive oxygen and nitrogen species, proliferative capacity, and glycolytic enzyme levels.

101 e present study, we evaluated the viability, proliferative capacity, and in vivo engraftment of myoge

102 hibited decreased Th1 cytokine secretion and proliferative capacity, and reduced Lck expression.

103 other hPAFc subunits, alters the morphology, proliferative capacity, and tamoxifen sensitivity of ERa

104 tly inhibited, and effector function but not proliferative capacity are ameliorated upon secondary st

105 timal cell size whereby cellular fitness and proliferative capacity are maximized.

106 ts (MEFs) lacking Tm5NM1, which have reduced proliferative capacity, are insensitive to inhibition of

107 pairment of resident cardiac progenitor cell proliferative capacity associated with altered canonical

108 ther suggesting persistence of cardiomyocyte proliferative capacity beyond the perinatal period.

109 s accompanied by restoration of keratinocyte proliferative capacity both in vivo and in vitro and by

110 on of p27(kip1) in Hrd1-null T-cells rescues proliferative capacity but not the production of cytokin

111 Dysfunctional telomeres limit cellular proliferative capacity by activating the p53-p21- and p1

112 ter fourth transfection increased fibroblast proliferative capacity by an additional 15.2 +/- 1.1 PDs

113 cadherin transition (N-Cadh(low+)); retained proliferative capacity (c-myc(+)); irregular stemness (S

114 of gene expression reflecting differences in proliferative capacity, cell adhesion functions and mito

115 Furthermore, the proliferative capacity (cellular output) of individual a

116 use myeloid progenitors that showed enhanced proliferative capacity compared to cells transduced with

117 asts from R258C patients exhibited increased proliferative capacity compared with controls, consisten

118 to UV-induced apoptosis but no difference in proliferative capacity compared with melanocytes derived

119 ilution assay was used for the assessment of proliferative capacity comparing T cell-dependent and T

120 negative for CD133, and possess an unlimited proliferative capacity, consistent with CD133+ cells bei

121 iPSCs produced myeloid cells with increased proliferative capacity, constitutive activation of granu

122 Loss of proliferative capacity correlated with a switch from the

123 r mixed-effects model analyses show that the proliferative capacity, cytokine production, and kinetic

124 o association between antiviral efficacy and proliferative capacity, cytotoxicity, polyfunctionality,

125 cells are counterbalanced by their increased proliferative capacity, driving the efficacy of the RTE

126 rneal endothelial cells (HCECs) have limited proliferative capacity due to "contact-inhibition" at G1

127 majority of HIV-specific CD8(+) T cells lose proliferative capacity during chronic infection, T cells

128 chronic stimulation retained functional and proliferative capacity during latency and subsequent rea

129 ts were able to recover their morphology and proliferative capacity during prolonged culture in mediu

130 Lymphocytes with reduced proliferative capacity exhibited increased proliferation

131 efforts to generate mature hepatocytes with proliferative capacity for cell-based therapeutics and f

132 that giant Hodgkin and RS cells have little proliferative capacity, further supporting small mononuc

133 were assessed after thawing for morphology, proliferative capacity, gene expression, and ability to

134 To test the effect of oxidative stress on proliferative capacity, HCECs cultured from young donors

135 KT cells that probably impart differences in proliferative capacity, homing, and effector functions.

136 ype counterparts, these cells show increased proliferative capacities in response to polyclonal stimu

137 er, differentiated melanocytes may also have proliferative capacity in animals, and the potential for

138 CD25+ cells exhibited a striking increase in proliferative capacity in coculture with CD4 T cells tha

139 s a key, lineage-specific determinant of the proliferative capacity in stem cells of stratified epith

140 lular signal-regulated kinase and AKT, minor proliferative capacity in the absence of an exogenous gr

141 EryP progenitors exhibited remarkable proliferative capacity in the yolk sac immediately befor

142 the goal of identifying targets to heighten proliferative capacity in this setting.

143 tional cell lines decreases self-renewal and proliferative capacity in vitro and tumor initiation and

144 evel of mitochondrial metabolism and reduced proliferative capacity in vitro, compared with controls.

145 samples supports an association of GPC5 with proliferative capacity in vivo.

146 memory cells, which are long-lived and high proliferative capacity, in the T cell zone of the spleen

147 Proliferative capacity increased in a dose-dependent man

148 These cells have decreased proliferative capacity, increased activation of senescen

149 en and CNS of these mice displayed decreased proliferative capacity, increased apoptosis, and up-regu

150 Tumor proliferative capacity is a major biological correlate o

151 egulatory relationships can unleash enhanced proliferative capacity is dependent upon the coupling of

152 Although proliferative capacity is the strongest single discrimin

153 in vivo The expression of Ki67, a marker of proliferative capacity, is predictive of expression of v

154 dy was to examine the functional competence (proliferative capacity, maintenance of telomeric reserve

155 CD8(+) T cells that, because of their higher proliferative capacity, may be suited best to eliminate

156 BE3A-mediated SIRT6 degradation promoted the proliferative capacity, migration potential, and invasiv

157 lasma LPS in vivo significantly alter T cell proliferative capacity, monocyte cytokine release, and H

158 Their proliferative capacity must be tightly regulated to prev

159 oliferation throughout life, deciphering why proliferative capacity normally dissipates in adult mamm

160 ary infection was normal with regards to the proliferative capacity, number of Ag-specific cells, cyt

161 Age-dependent and topographical decreases in proliferative capacity observed in HCECs resulted, at le

162 ngs suggest that the self-renewal and robust proliferative capacities of memory T cells are associate

163 rming assays reveal that the engraftment and proliferative capacities of TECs diminish early in life,

164 ntreated cells, whereas the morphologies and proliferative capacities of the endothelial cells were n

165 is associated with a massive decline of the proliferative capacities of the stem cell niche in the a

166 The morphology, the self-renewal and proliferative capacities of the subclones differed.

167 Telomere shortening limits the proliferative capacity of a cell, but perhaps surprising

168 rating pool and the number of divisions, the proliferative capacity of a significant proportion of HI

169 e cardiac regeneration in mammals is the low proliferative capacity of adult cardiomyocytes.

170 th hypoxic cell growth, thereby limiting the proliferative capacity of adult cells under low oxygen t

171 lucidating the mechanism underlying the poor proliferative capacity of adult pancreatic beta-cells is

172 This restraint might be because of the poor proliferative capacity of aged donor hepatocytes or the

173 l, our data indicate that the intrinsic over-proliferative capacity of APC(-/-) cells is not uncontro

174 MOZ was required to maintain the proliferative capacity of B-cell progenitors, even in th

175 Loss of proliferative capacity of balding DPC was associated wit

176 uce type 1 diabetes was not due to decreased proliferative capacity of BDC2.5 clonotypic-like cells.

177 proliferation while having no effect on the proliferative capacity of beryllium-responsive CD4(+) T

178 circulating blood cell counts and increased proliferative capacity of bone marrow derived cells.

179 ) (Cdkn1a), a factor associated with reduced proliferative capacity of both hematopoietic and neurona

180 We conclude that the aberrant proliferative capacity of Brca1(-/-) luminal progenitor

181 lase activity plays an important role in the proliferative capacity of breast cancer cells through re

182 Examination of the proliferative capacity of C/EBPalpha-S193A livers showed

183 that while OX40 costimulation augmented the proliferative capacity of CD28-costimulated Tregs, Foxp3

184 imotope stimulation tested the frequency and proliferative capacity of CD4 BDC2.5-like cells.

185 ion resulted in significant reduction in the proliferative capacity of cells.

186 is a form of cellular aging that limits the proliferative capacity of cells.

187 rimarily reflects increases in abundance and proliferative capacity of cortical progenitors and in th

188 The proliferative capacity of CSP cells was also tested afte

189 e single-cell pick-up assay, we examined the proliferative capacity of cultured PGCs in response to W

190 Cellular senescence limits the proliferative capacity of damaged cells and thereby acts

191 onship between prometaphase duration and the proliferative capacity of daughter cells.

192 ase not only in the percentages but also the proliferative capacity of different populations of cardi

193 The proliferative capacity of differentiated acinar cells ma

194 stem cells, and its set point determines the proliferative capacity of differentiated cell lineages b

195 helial NO synthase coupling and enhanced the proliferative capacity of ECs and circulating endothelia

196 The proliferative capacity of enriched splenocyte T-cell pre

197 ion and hypoplasia, accompanied by a reduced proliferative capacity of epidermal progenitor cells.

198 e data identify Yap1 as a determinant of the proliferative capacity of epidermal stem cells and as an

199 elerated telomere shortening, and diminished proliferative capacity of hematopoietic progenitors.

200 kade of the IL-10 pathway augmented in vitro proliferative capacity of HIV-specific CD4 and CD8 T cel

201 -1 and 2B4 inhibitory pathways increased the proliferative capacity of HIV-specific CD8(+) T cells.

202 The proliferative capacity of HIV-specific CD8+ T cells was

203 simplicity of this system and the unlimited proliferative capacity of Hoxb8-FL cells will enable stu

204 tein expression can be used to determine the proliferative capacity of hPSC-derived cardiomyocytes.

205 complete HPV31 genomes resulted in impaired proliferative capacity of HPV-positive keratinocytes fol

206 Specifically, ANG reduces the proliferative capacity of HSPC while simultaneously incr

207 ta indicate that Hbz expression enhances the proliferative capacity of HTLV-1-infected T cells, playi

208 Telomere shortening limits the proliferative capacity of human cells, and age-dependent

209 pe will be required in order to exploit high proliferative capacity of human embryonic stem cells and

210 downstream of Dvl2 cooperate to maintain the proliferative capacity of human glioblastomas.

211 l or other stimuli capable of sustaining the proliferative capacity of immature cardiomyocytes or sti

212 This segregation coassociated with the proliferative capacity of iNKT cells between the 2 group

213 As the proliferative capacity of interstitial macrophages decli

214 ceptor signaling is required to maintain the proliferative capacity of ISCs.

215 The proliferative capacity of Ki-67+ perivascular macrophage

216 The ex vivo proliferative capacity of M. tuberculosis-specific CD4 T

217 possible mechanism contributing to impaired proliferative capacity of M. tuberculosis-specific CD4 T

218 iciency is manifest as modest defects in the proliferative capacity of mature B cells and their diffe

219 genesis but necessary for achieving the full proliferative capacity of MCs.

220 ven partial inhibition of MOZ may reduce the proliferative capacity of MEIS1, and HOX-driven lymphoma

221 The proliferative capacity of melanoma cells was suppressed

222 nes (including BCL2) and resulted in reduced proliferative capacity of melanoma cells.

223 mice are characterized by limited number and proliferative capacity of MK progenitors.

224 Ectopic FOXM1 rescues the proliferative capacity of MYC- or p53-mutant cells in sp

225 ber explants demonstrated an increase in the proliferative capacity of myofiber-associated satellite

226 tent with a model in which exhaustion of the proliferative capacity of naive T cells causes a sharp d

227 ment to control the exit from quiescence and proliferative capacity of NB as well as neuron productio

228 A more robust in vitro proliferative capacity of nCPCs, compared with aCPCs, co

229 ed Notch1 or its ligand Jagged1 expanded the proliferative capacity of neonatal cardiomyocytes; this

230 e reported that FoxO maintains the long-term proliferative capacity of neural stem/progenitor cells (

231 a distinct downstream effectors to alter the proliferative capacity of NPCs.

232 liferate, but blockade of B7-H1 restored the proliferative capacity of old CD8(+) T cells to a level

233 Increased proliferative capacity of outer progenitors is further p

234 ations of mouse epidermis robustly increases proliferative capacity of p63(+) epidermal progenitor ce

235 n of B cell memory; instead, SpA reduced the proliferative capacity of PCs that entered the BM, dimin

236 , it was determined that there was a reduced proliferative capacity of PD-1(high) compared with PD-1(

237 d primarily by cytogenetic abnormalities and proliferative capacity of plasma cells.

238 Instead, miR-17~92 increased the proliferative capacity of Rb/p107-deficient retinal cell

239 ve neonatal hypocellularity due to decreased proliferative capacity of rescued apical and outer radia

240 ring rechallenge, indicating that the robust proliferative capacity of RTEs was maintained independen

241 Despite their compromised proliferative capacity of RUNX1S291fs/Ezh2-null MDS cell

242 of Sox2(+) cells and suggest that persistent proliferative capacity of Sox2(+) cells may underlie the

243 s associated with partial restoration of the proliferative capacity of splenocytes from infected anim

244 Short telomeres block the proliferative capacity of stem cells, affecting their po

245 In vitro, LR-MSCs profoundly suppressed the proliferative capacity of T cells in response to a mitog

246 are driven by cell-intrinsic changes in the proliferative capacity of TECs, and further show that yo

247 transcriptional activator, conferring higher proliferative capacity of the affected cells.

248 yped cleavage pattern of the 4d lineage, the proliferative capacity of the blast cells, and the marke

249 n be completed in 4-8 weeks depending on the proliferative capacity of the cell line.

250 tor for PCO in this study, whereas intrinsic proliferative capacity of the individual's lens epitheli

251 epithelia; blocking this pathway reduces the proliferative capacity of the intestinal stem cells.

252 lammatory response, and the regenerative and proliferative capacity of the intestine following an acu

253 role for this orphan GPCR in regulating the proliferative capacity of the intestine.

254 recursor pool of cells by affecting both the proliferative capacity of the progenitors as well as aff

255 T cells completed, no change in the per cell proliferative capacity of the remaining Ag-specific T ce

256 Finally, we showed that the impaired proliferative capacity of the T cells was caused by pers

257 somatic mosaicism correlates poorly with the proliferative capacity of the tissue and rates of cell t

258 y for human cancers, genes essential for the proliferative capacity of their stem cells remain unknow

259 in true naive T cell precursors and impaired proliferative capacity of their VM cousins--combine to r

260 In addition, the proliferative capacity of these NCC is also diminished.

261 CAM-1 expression is abolished, the secondary proliferative capacity of these T cells is severely curt

262 the formation of neurospheres, affected the proliferative capacity of transformed neurons and reduce

263 liferating conventional T cells, whereas the proliferative capacity of Treg cells in cell cultures re

264 The proliferative capacity of tumor cells of the IL-12 KO mi

265 iral replication is associated with impaired proliferative capacity of virus-specific CD8+ T cells an

266 Signaling mechanisms that maintain the proliferative capacity of VZ resident progenitors remain

267 lation doublings, its deficiency impairs the proliferative capacity of WI-38 cells.

268 in normal stratifying epithelia to maintain proliferative capacity or drive proliferation of squamou

269 ing livers showed little initial evidence of proliferative capacity or function.

270 LiPs in long-term culture did not lose their proliferative capacity or their hepatic differentiation

271 stigates the effects of aspirin (ASA) on the proliferative capacity, osteogenic potential, and expres

272 ignificantly associated with increased tumor proliferative capacity (p = 0.0238) and borderline with

273 lymph node metastases (p = 0.0571) and tumor proliferative capacity (p = 0.0576).

274 of megakaryocyte progenitors with restricted proliferative capacity persist in E10.5 yolk sac and E11

275 ar stress has been associated with a loss in proliferative capacity (premature senescence) of corneal

276 d determined the effects of acrolein on cell proliferative capacity, senescence-associated beta-galac

277 in nuclear 8-OHdG staining and a decrease in proliferative capacity similar to that observed in untre

278 tment on the microarray and a reduced lympho proliferative capacity, suggesting clear differences in

279 terminally differentiated cells with limited proliferative capacity (T(EMRA)).

280 TCM exhibit greater plasticity and proliferative capacity than effector memory T cells (TEF

281 d and third transfections had less effect on proliferative capacity than the first, revealing a refra

282 antigen-specific T cells display an impaired proliferative capacity that is caused by increased expre

283 pulation was stable over time and retained a proliferative capacity that was vastly superior to TEFF.

284 Indeed, their short lifespan, the absent proliferative capacity, their limited ability to produce

285 in astrocytes, which, unlike neurons, retain proliferative capacity throughout life.

286 es of VZV-specific CD4(+) T cells, including proliferative capacity to VZV antigen stimulation and id

287 4 overexpression in adult SVZ cells restores proliferative capacity to wild-type levels.

288 , but they exhibited a significantly reduced proliferative capacity upon secondary challenge while re

289 s of IkappaBepsilon in B cells; it regulates proliferative capacity via at least two mechanisms invol

290 t M. tuberculosis-specific degranulation and proliferative capacities were impaired in the HIV-infect

291 CPC differentiation, whereas CPC number and proliferative capacity were increased.

292 perforin/granzyme-mediated cytotoxicity and proliferative capacity were not affected by APG101 treat

293 One subtype was defined by reduced proliferative capacity, whereas the other two subtypes (

294 omeres develop increased damage with reduced proliferative capacity, which suggests an important role

295 stimulated through the TCR displayed reduced proliferative capacity, which was restored by inhibiting

296 lls reduce their intercellular adhesions and proliferative capacity while gaining a mesenchymal pheno

297 pH for approximately 3 months restored their proliferative capacity while maintaining the cytoplasmic

298 l tumor cells (MEC) were reduced in size and proliferative capacity, with reduced cyclin D1 and p27(K

299 to act as cryptic progenitors and reacquire proliferative capacity within the context of mucosal inj

300 d of extending telomeres and increasing cell proliferative capacity without risk of insertional mutag