ライフサイエンスコーパス: proline-rich tyrosine kinase 2

1 and Syk that activated the downstream kinase proline-rich tyrosine kinase 2.

2 endent on protein kinase C, Src kinases, and proline-rich tyrosine kinase 2.

3 ation and the concomitant phosphorylation of proline-rich tyrosine kinase 2.

4 focal tyrosine kinase (RAFTK), also known as proline-rich tyrosine kinase 2 and cellular adhesion kin

5 DPH oxidase, Syk, focal adhesion kinase, and proline-rich tyrosine kinase 2, and in the absence of De

6 lying this process: a phospholipase C/Ca(2+)/proline-rich tyrosine kinase 2/cJun N-terminal kinase pa

7 ion of the dantrolene-sensitive, nonreceptor proline-rich tyrosine kinase-2; components of the extrac

8 rc-dependent tyrosine phosphorylation of the proline-rich tyrosine kinase 2, epidermal growth factor

9 he nonreceptor protein-tyrosine kinase Pyk2 (proline-rich tyrosine kinase 2) has been shown previousl

10 Inhibition of proline-rich tyrosine kinase 2 improved insulin-induced

11 ha increased the tyrosine phosphorylation of proline-rich tyrosine kinase 2 in acinar cells.

12 vement of protein kinase C, Src kinases, and proline-rich tyrosine kinase 2 in the process.

13 Proline-rich tyrosine kinase 2, in turn, caused activati

14 ed that protein kinase C delta and , but not proline-rich tyrosine kinase 2, mediate tumor necrosis f

15 nhibited tumor necrosis factor-alpha-induced proline-rich tyrosine kinase 2 phosphorylation, but at d

16 e focal adhesion kinase [FAK] family members proline-rich tyrosine kinase 2 [Pyk-2] and FAK) was also

17 Proline-rich tyrosine kinase 2 (pyk2) activity is enhanc

18 transducer) was mediated by FA formation and proline-rich tyrosine kinase 2 (PYK2) activity.

19 sine kinases focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) and also reduces t

20 ctivation of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) and their increase

21 In cultured cells, phosphorylation of a FAK/proline-rich tyrosine kinase 2 (PYK2) consensus site in

22 udy investigates the role of the nonreceptor proline-rich tyrosine kinase 2 (PYK2) in Ang II-induced

23 Despite the involvement of proline-rich tyrosine kinase 2 (Pyk2) in endothelial cel

24 Proline-rich tyrosine kinase 2 (Pyk2) is a cytoplasmic t

25 Proline-rich tyrosine kinase 2 (PYK2) is a cytoplasmic,

26 Proline-rich tyrosine kinase 2 (Pyk2) is a member of the

27 Proline-rich tyrosine kinase 2 (Pyk2) is a member of the

28 Proline-rich tyrosine kinase 2 (Pyk2) is a novel cytosol

29 Cumulative in vitro studies indicated that proline-rich tyrosine kinase 2 (PYK2) is a positive medi

30 Proline-rich tyrosine kinase 2 (Pyk2) is activated by va

31 Indeed, expression of the FAK-related proline-rich tyrosine kinase 2 (Pyk2) is elevated and ph

32 A new study in this issue shows that proline-rich tyrosine kinase 2 (Pyk2) is responsible for

33 Proline-rich tyrosine kinase 2 (PYK2) is the main adhesi

34 FAK and its homolog Proline-rich tyrosine kinase 2 (Pyk2) modulate paxillin

35 results reveal that tyrosine kinases Src and proline-rich tyrosine kinase 2 (Pyk2) regulate SHP-1-dep

36 The proline-rich tyrosine kinase 2 (Pyk2) was first identifi

37 Proline-rich tyrosine kinase 2 (PYK2), a major cell adhe

38 Proline-rich tyrosine kinase 2 (PYK2), a redox-sensitive

39 Proline-rich tyrosine kinase 2 (PYK2), a tyrosine kinase

40 Proline-rich tyrosine kinase 2 (PYK2), also known as cel

41 Proline-rich tyrosine kinase 2 (PYK2), also known as cel

42 lated adhesion focal tyrosine kinase (RAFTK)/proline-rich tyrosine kinase 2 (PYK2), an upstream effec

43 to-oncogene tyrosine-protein kinase) and the proline-rich tyrosine kinase 2 (Pyk2), and they can also

44 The FAK-related kinase, proline-rich tyrosine kinase 2 (Pyk2), is expressed in F

45 actin as a novel substrate and interactor of proline-rich tyrosine kinase 2 (Pyk2).

46 erentiation primary response gene-88 (MYD88)/proline-rich tyrosine kinase 2 (PYK2)/LYN complexes, whi

47 the calcium-regulated focal adhesion protein proline-rich tyrosine kinase-2 (Pyk2) and the effector p

48 Here we demonstrate that proline-rich tyrosine kinase-2 (PYK2) deficiency impairs

49 yrosine autophosphorylation (Tyr-402) of the proline-rich tyrosine kinase-2 (PYK2) without significan

50 kinases, focal adhesion kinase (FAK) and/or proline-rich tyrosine kinase-2 (Pyk2), based on two line

51 ical protein kinase Cs (aPKCs) by activating proline-rich tyrosine kinase-2 (PYK2), ERK pathway compo

52 tochalasin B-inhibitable; (b) dependent upon proline-rich tyrosine kinase-2 (PYK2), GRB2, SOS, RAS, R

53 Inhibition of proline-rich tyrosine kinase 2 restores insulin-induced

54 sults suggest that in cells expressing RAFTK/proline-rich tyrosine kinase 2, such as endothelial and

55 itory residue Y657 of eNOS and expression of proline-rich tyrosine kinase 2 that phosphorylates this

56 actin, Wiskott-Aldrich syndrome protein, nor proline rich tyrosine kinase-2 to the target cell contac

57 Tumor necrosis factor-alpha activates proline-rich tyrosine kinase 2 to cause cytoskeletal dis

58 owed that protein kinase C delta and mediate proline-rich tyrosine kinase 2 tyrosine phosphorylation.

59 sfected with small interfering RNA targeting proline-rich tyrosine kinase-2, which was also phosphory