ライフサイエンスコーパス: prolonged period

1 rturbations can have profound effects over a prolonged period.

2 cell line and treated with paclitaxel for a prolonged period.

3 ntain low contact rates among children for a prolonged period.

4 on of the molecular targets of OSI-930 for a prolonged period.

5 T cells were retained within the lungs for a prolonged period.

6 CAR remained in the blood circulation for a prolonged period.

7 e produced at an exaggerated level and for a prolonged period.

8 uester nascent polypeptides for a relatively prolonged period.

9 an infectious HCV human serum inoculum for a prolonged period.

10 released to the systemic circulation over a prolonged period.

11 inally dependent on CD4(+) T cell help for a prolonged period.

12 g agent at a physical site in the body for a prolonged period.

13 n the brain to completely inhibit FAAH for a prolonged period.

14 an be expanded and maintained in culture for prolonged periods.

15 separation from mechanical ventilation over prolonged periods.

16 r histocompatibility complex I molecules for prolonged periods.

17 s (DCs) and prevents steady tumor growth for prolonged periods.

18 hat can hold the tumor in dormant stages for prolonged periods.

19 ote any detectable desensitization, even for prolonged periods.

20 ty for memory B cells to sample antigen over prolonged periods.

21 or to probe dynamic changes repeatedly over prolonged periods.

22 rage in medium at different temperatures for prolonged periods.

23 l use, especially at high infusion rates for prolonged periods.

24 inducing or repressing SNAT2 expression for prolonged periods.

25 tumor-stromal cell interactions in situ for prolonged periods.

26 (LPS) was administered intraperitoneally for prolonged periods.

27 NF)-alpha, and IL-2, and in high amounts for prolonged periods.

28 ts shed low-pathogenic influenza viruses for prolonged periods.

29 -/-) airways of mice exposed to allergen for prolonged periods.

30 is administered in a prevention setting for prolonged periods.

31 used as an infusion to provide sedation for prolonged periods.

32 maintained their cardiac grafts for markedly prolonged periods.

33 en androgen deprivation is administered over prolonged periods.

34 s the evoked excitability of PFC neurons for prolonged periods.

35 yperoxia in the lung continue to survive for prolonged periods.

36 essed, T.brucei can evade immune killing for prolonged periods.

37 eritis and colonize the intestinal tract for prolonged periods.

38 tion, but latently infected cells remain for prolonged periods.

39 pathways by which infected cells persist for prolonged periods.

40 response and are able to remain off ADT for prolonged periods.

41 h enhanced temporal and spatial control over prolonged periods.

42 isions made around antibiotic treatment over prolonged periods.

43 octurnal IOP elevation in living animals for prolonged periods.

44 udying endothelial dysfunction in vitro over prolonged periods.

45 ssion are rapid, homogeneous and stable over prolonged periods.

46 ng that this variant may colonize humans for prolonged periods.

47 hern elephant seals are naturally adapted to prolonged periods (1-2 months) of food deprivation (fast

48 h to withstand strong cross-flow shear for a prolonged period (120 h) while maintaining NaCl rejectio

49 ned asymptomatic carriage and infection over prolonged periods; (2) an epidemic clone, ST8:S, demonst

50 Rat hearts, exposed to a prolonged period (24 h) of cold (4 degrees C) ischemia,

51 cells were able to sustain hematopoiesis for prolonged periods (9 months) and were able to engraft se

52 hese agents in rats exposed to hyperoxia for prolonged periods, a common model of acute lung injury.

53 in vivo insulin delivery at basal level for prolonged period after a single subcutaneous injection.

54 Airway narrowing is maintained for a prolonged period after acute bronchoconstriction in huma

55 PKCgamma remained in these structures for a prolonged period after the response in the soma ceased.

56 whose cardiac defects remain unrepaired for prolonged periods after birth.

57 Liver tissue remained intact over prolonged periods after death in non-heart-beating donor

58 cripts were induced to a greater extent over prolonged periods after infection with a T-DNA transfer-

59 generate cAMP and promote PKA activation for prolonged periods after ligand washout and receptor inte

60 might be that the brain remained hypoxic for prolonged periods after resuscitation.

61 ebellar nuclei fire at accelerated rates for prolonged periods after trains of synaptic inhibition th

62 f gamma2(+/-) mice to wild-type levels for a prolonged period, along with antidepressant-like behavio

63 Female mice remained in estrus for prolonged periods and produced almost 50% more litters p

64 racteristic of early prophase persists for a prolonged period, and homologs dissociate prematurely; f

65 slowly released locally within the tumor for prolonged periods; and (iii) the siG12D LODER elicits a

66 In the absence of T-cell help for prolonged periods, anti-Gal B cells exposed to alpha-gal

67 tic trials in large numbers of patients over prolonged periods are urgently required.

68 ant PrcB and PrcA in Escherichia coli over a prolonged period at 37 degrees C allowed formation of an

69 ture but display aberrant organization after prolonged periods at 37 degrees C.

70 ace pressures, and can remain metastable for prolonged periods at pressures approaching 70 mN/m.

71 ague can persist in prairie-dog colonies for prolonged periods, because host movement is highly spati

72 er larva stage, enabling them to survive for prolonged periods before completing development.

73 ally infused into the dorsal hippocampus for prolonged periods beginning within hours after rats sust

74 ere within the immunosuppressive range for a prolonged period, but with no observable clinically sign

75 n decouple respiration from assimilation for prolonged periods by mobilizing reserves from transport

76 Nocturnal elevation of IOP blocked for prolonged periods by transferred RhoA gene.

77 sures, suggesting that activity mapping over prolonged periods can identify areas of activity that ar

78 These observations suggest that the prolonged period during which multisensory integration n

79 K virus-specific T-cell immunity may require prolonged periods during which cytopathic damage may con

80 the labeled nanoparticles remain stable for prolonged periods, during cell division, the changes in

81 that high levels of circulating lipids for a prolonged period elevated CD4(+) and CD8(+) T cell proli

82 assessments of cell counts (homing) or after prolonged periods (engraftment).

83 isely timed signals to the cerebellum over a prolonged period following a stimulus, which may also bo

84 m and draining mediastinal lymph nodes for a prolonged period following bacterial clearance.

85 lly very poor, some patients can survive for prolonged periods following metastasis.

86 and as a means to release drug locally over prolonged periods for prevention of locoregional recurre

87 The prolonged period from insult to death suggests that the

88 d the sieve elements, the GPA fed for a more prolonged period from sieve elements of adf3 compared to

89 transmission in large geographical areas for prolonged periods further supports the feasibility of er

90 ablished, the cultures can be maintained for prolonged periods (>6 weeks) permitting manipulations to

91 laced in the gastrointestinal (GI) tract for prolonged periods have the potential to transform clinic

92 its production of large amounts of NO for a prolonged period; hence, it was termed the high-output N

93 ty in patients with multiple sclerosis for a prolonged period in the absence of any ongoing disease-m

94 lomas retain their lymphoid structure over a prolonged period in the absence of chronic peritoneal in

95 ative to pressure support ventilation over a prolonged period in the complex ICU setting.

96 is mutant, Bub1, but not Mad2, remains for a prolonged period in the kinetochores that are situated i

97 nduced by oncogenic H-Ras and B-Raf, after a prolonged period in the senescence arrested state.

98 hat initial generalization was followed by a prolonged period in which new memories became distinguis

99 drites of mitral and tufted (M/T) cells over prolonged periods in adult mice.

100 and tissue levels of HMGB1 are elevated for prolonged periods in chronic and acute inflammatory cond

101 ycobacterium tuberculosis (Mtb) persists for prolonged periods in macrophages, where it must adapt to

102 mulative toxicity and controlled disease for prolonged periods in many patients, including some who w

103 es may enhance growth and/or survival during prolonged periods in natural habitats with limited nutri

104 indicate that neurofilaments pause for more prolonged periods in the absence of myosin Va.

105 m by which progenitor cells are retained for prolonged periods in the bone marrow.

106 hanges in starch accumulation patterns after prolonged periods in the light occurred at both high and

107 Following prolonged periods in this alkaline phase, Saccharomyces

108 he ability to maintain islets in culture for prolonged periods is an important step toward the develo

109 Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality

110 c, doses given on a close regular basis over prolonged periods, is an alternative and better tolerate

111 mulation that can be administered safely for prolonged periods makes it an attractive agent for long-

112 rants in HIV-infected cells that persist for prolonged periods may yield useful information regarding

113 neurons, which form synapses and survive for prolonged periods, mutant neurons do not mature and are

114 -order schedule of reinforcement, in which a prolonged period of alcohol-seeking behavior was maintai

115 larger rectal distensions, leading to a more prolonged period of anal relaxation.

116 nkage disequilibrium are best explained by a prolonged period of ancestral population subdivision fol

117 suppression can lead to reactivation after a prolonged period of clinical latency.

118 flowering, unless flowering is promoted by a prolonged period of cold (e.g. winter) known as vernaliz

119 es only flower after they have experienced a prolonged period of cold, a process known as vernalizati

120 by flowering is accelerated in response to a prolonged period of cold.

121 This model exhibits a prolonged period of cytopenias prior to transformation t

122 ty remained around 10% or less, even after a prolonged period of exposure.

123 The neurons also have a prolonged period of GABAergic depolarization characteris

124 Sustained Ikaros expression results in a prolonged period of generation of deep layer neurons int

125 The difference suggests a prolonged period of genetic exchange during the formatio

126 These results demonstrate that a prolonged period of hypoestrogenicity disrupts both neur

127 ation (BMT) is often delayed, resulting in a prolonged period of immunodeficiency.

128 human sepsis mortality often occurs during a prolonged period of immunosuppression and not from exagg

129 A prolonged period of increased apoptosis, beginning at 10

130 tients with locally advanced PC, following a prolonged period of induction systemic therapy, will be

131 tes in both humans and mice is preceded by a prolonged period of inflammation of pancreatic islets by

132 arly effective in young patients requiring a prolonged period of inflow occlusion, and in the presenc

133 of a transient excitation followed by a more prolonged period of inhibition, presumably reflecting di

134 cted status was rapid, with no evidence of a prolonged period of intermittent low-level viremia.

135 conclude that topical pTT treatment during a prolonged period of intermittent UV exposure decreases t

136 nditioning (short ischemic stress prior to a prolonged period of ischemia) and intermittent inflow oc

137 rfusion, at the onset of reperfusion after a prolonged period of ischemia, confer cardioprotection, a

138 gh initial drug concentration, followed by a prolonged period of low concentration).

139 o rearing relatively few offspring through a prolonged period of maturation.

140 esophageal acid exposure by discounting the prolonged period of mucosal contact with each acid reflu

141 The prolonged period of negativity for HCV RNA followed by r

142 proved function and did not relapse during a prolonged period of observation.

143 Data suggest that initiating a prolonged period of overeating may increase striatal res

144 es during the re-treatment period and a more prolonged period of remission during subsequent followup

145 creases in bleaching frequency, we predict a prolonged period of suppressed budget and reef growth st

146 However, the prolonged period of suppression of many clones suggests

147 not affect mucosal challenge outcome after a prolonged period of systemic infection with the nonpatho

148 transplantation (BMT) is often followed by a prolonged period of T cell deficiency.

149 This enhancement was due to a prolonged period of T cell proliferation, resulting in a

150 PfCRK4 is required for both a prolonged period of the intraerythrocytic stage of Plasm

151 s in which human tumors remain dormant for a prolonged period of time (>120 days) until they switch t

152 ultrasound, and release chemotherapy over a prolonged period of time (>90 days) resulting in signifi

153 f rats fed with a high dose of ethanol for a prolonged period of time (6 months).

154 aining PMAA-resin discs were sustained for a prolonged period of time (weeks and months).

155 average plasma glucose concentration over a prolonged period of time and is used to diagnose diabete

156 sed to tumor-conditioned medium (TCM) over a prolonged period of time assume a CAF-like myofibroblast

157 xposure to physiologic levels of Abeta for a prolonged period of time causes microstructural changes

158 o etomidate for maintaining anesthesia for a prolonged period of time in patients with sepsis.

159 dicating that plasma cells may persist for a prolonged period of time in the absence of cell division

160 pable of firing in a sustained manner over a prolonged period of time, especially when they are drive

161 yces cerevisiae are starved of glucose for a prolonged period of time, gluconeogenic enzymes such as

162 tion, using clinically relevant doses over a prolonged period of time, without systemic toxicity.

163 tissues remained depleted of NK cells for a prolonged period of time.

164 ncentrations of drug at the tumor site for a prolonged period of time.

165 suppressed insulin receptor signaling over a prolonged period of time.

166 ncidence in a majority of treated mice for a prolonged period of time.

167 imolar conditions or when crystallized for a prolonged period of time.

168 ten requires multimodality treatments over a prolonged period of time.

169 and be drug loadable and release drug over a prolonged period of time.

170 leads to decreased anabolic hormones over a prolonged period of time.

171 and are capable of controlled release for a prolonged period of time.

172 n clinical cases, can remain uncertain for a prolonged period of time.

173 lso needs to clear the cell of SAMHD1 over a prolonged period of time.

174 when the MAbs interact with the virus for a prolonged period of time.

175 the Holocene, and we suggest that the recent prolonged period of warming in the Antarctic Peninsula r

176 Even after prolonged periods of abstinence, addicts are at risk of

177 as indicated through the more immediate and prolonged periods of activation within the LH and APC, r

178 e support has rapidly expanded and allow for prolonged periods of apneic airway surgery.

179 ently infected, resting CD4+ T cells despite prolonged periods of aviremia.

180 presumed unfavorable conditions: even after prolonged periods of blood vessel ablation, basal and st

181 cell is sufficiently dynamic to prevent the prolonged periods of burst firing which can be evoked in

182 n and that therapeutic intervention to avoid prolonged periods of CD4(+) lymphopenia may be desirable

183 tion response to low temperatures, such that prolonged periods of chilling induced dormancy in nondor

184 h the safer use of liver transplants despite prolonged periods of cold ischemia.

185 orthotopic liver transplantation (OLT) after prolonged periods of cold ischemia.

186 ceptor type 1 (APT070) and then subjected to prolonged periods of cold storage (at 4 degrees C).

187 strategy is particularly adapted to provide prolonged periods of continuous noninvasive mechanical v

188 reezing) Eocene climate on Ellesmere Island, prolonged periods of darkness occurred during the winter

189 d muscle pain, rashes, and fever, as well as prolonged periods of disability in some patients.

190 drug seeking and episodes of relapse despite prolonged periods of drug abstinence.

191 the present study suggest that analyses from prolonged periods of either sensory deprivation or stimu

192 with increased post-injury intervals and/or prolonged periods of exercise.

193 Prolonged periods of extreme heat or drought in the firs

194 udy emphasizes the importance of considering prolonged periods of food deprivation when assessing che

195 nd-order schedule of reinforcement, in which prolonged periods of food-seeking behavior were maintain

196 chambers able to maintain pregnant sheep for prolonged periods of gestation under controlled signific

197 Thus, prolonged periods of homeostatic expansion can temporari

198 high-dose biochemotherapy or rIL-2 requiring prolonged periods of hospitalization, or single agent ou

199 c GVHD mouse model, fucosylated Tregs showed prolonged periods of in vivo persistence.

200 muscle atrophy is reversible, and even after prolonged periods of inactivity, myofiber degeneration i

201 ivity of a neuron or neuronal circuit during prolonged periods of increased network activity and have

202 MPs) contribute to regional remodeling after prolonged periods of ischemia and reperfusion (I/R), but

203 ience in male rats when followed by short or prolonged periods of loss of sex reward causes enhanced

204 During prolonged periods of maternal separation, although infan

205 phrenia free from the potential confounds of prolonged periods of medication and disease interactions

206 least two antipsychotic medications, and had prolonged periods of moderate to severe positive or nega

207 roducibly recoverable from communities after prolonged periods of no-BAC exposure, suggesting that th

208 t immune system and drug regimes by entering prolonged periods of non-proliferation or dormancy.

209 risingly, the amount of LDs increases during prolonged periods of nutrient deprivation.

210 he Rel/Spo family enable bacteria to survive prolonged periods of nutrient limitation by producing an

211 need to provide anesthetic stability during prolonged periods of one-lung ventilation, while optimiz

212 Prolonged periods of pepsin-mediated Pen a 1 proteolysis

213 onsequently, serious adverse events, such as prolonged periods of profound myelosuppression, contribu

214 ic changes that enable Leishmania to survive prolonged periods of purine starvation.

215 ls have eventually developed rejection after prolonged periods of rejection-free survival off therapy

216 the complex demographic approaches predicted prolonged periods of relatively stable carbon densities

217 Studies that use prolonged periods of sensory stimulation report associat

218 physical activity, as well as the effects of prolonged periods of shallow breathing.

219 Prolonged periods of simulated microgravity did not caus

220 al course varies from rapid deterioration to prolonged periods of stability that are unpredictable by

221 They have stable firing rates during prolonged periods of stimulation and respond to a wide r

222 13]-a feat that would be impossible without prolonged periods of straight flight.

223 alization of EF1alpha mRNA is not altered by prolonged periods of synaptic activation that are suffic

224 and the ability to survive the dry state for prolonged periods of time (longevity) are two essential

225 IL-2(-/-) T cells were unable to survive for prolonged periods of time after adoptive transfer in unm

226 hanism that integrates energetic status over prolonged periods of time and allows them to recover fun

227 ardia where the channels are depolarized for prolonged periods of time and could induce Ca(2+) overlo

228 We show that pDCs can preserve Ags for prolonged periods of time and on stimulation show strong

229 these cells can be maintained in culture for prolonged periods of time and used for extensive biochem

230 er of oxidative and inflammatory damage over prolonged periods of time as well as brief episodes of i

231 oocytes are maintained in meiotic arrest for prolonged periods of time before undergoing oocyte matur

232 fore being diagnosed, a tumor can remain for prolonged periods of time in a dormant state.

233 und that retinal neurons remain immature for prolonged periods of time in far peripheral regions of t

234 tion of perisomatic inhibitory synapses over prolonged periods of time in hippocampal slice cultures.

235 but the most severely injured patients spend prolonged periods of time in LOCs, and many require crit

236 Systems capable of residing for prolonged periods of time in the gastric cavity have tra

237 O-BsubPc) do not hydrolyze at all even after prolonged periods of time in the presence of water.

238 valuation of the catalytic performance after prolonged periods of time showed that a water molecule i

239 aining high intracellular concentrations for prolonged periods of time which appears to promote longe

240 administration is safe and can block KIR for prolonged periods of time with limited side effects.

241 ces, are stable against common chemicals for prolonged periods of time, and can be used in applicatio

242 ell cycle remain in a state of readiness for prolonged periods of time, and may represent a populatio

243 urfaces, biofilm formation was inhibited for prolonged periods of time, and the DMAE excelled in the

244 rowing along the natural gravity vector over prolonged periods of time, as well as the ability to ind

245 successful at keeping viruses suppressed for prolonged periods of time, but therapy failures attribut

246 atients exhibiting stability of symptoms for prolonged periods of time, whereas others exhibit rapid

247 who are aged and/or deprived of estrogen for prolonged periods of time.

248 n stable with limited spatial migration over prolonged periods of time.

249 when myocardial perfusion is interrupted for prolonged periods of time.

250 tem cells to remain in a quiescent state for prolonged periods of time.

251 ulates in macrophages when administered over prolonged periods of time.

252 n the devices are exposed to ambient air for prolonged periods of time.

253 d in patients with anorexia nervosa (AN) for prolonged periods of time.

254 al artificial hearts that could function for prolonged periods of time.

255 sion from onset and document its course over prolonged periods of time.

256 en receiving effective antiviral therapy for prolonged periods of time.

257 synapses, which release neurotransmitter for prolonged periods of time.

258 be shed by immunocompromised individuals for prolonged periods of time.

259 rgic system in a highly selective manner for prolonged periods of time.

260 suppressed below the limit of detection for prolonged periods of time.

261 nd four patients were rendered pain-free for prolonged periods of time.

262 viremia has been successfully suppressed for prolonged periods of time.

263 phase-lock with submillisecond precision for prolonged periods of time.

264 ith stable binary complexes that extend over prolonged periods of time.

265 hether units could be followed reliably over prolonged periods of times in these two areas, including

266 eramide induce an inhibition of Akt, whereas prolonged periods of treatment show an additive inhibiti

267 Exposure of donor liver grafts to prolonged periods of warm ischemia before procurement ca

268 h the safer use of liver transplants despite prolonged periods of warm or cold ischemia, or both.

269 Studies suggest that the VZV may persist for prolonged periods on the cornea after herpes zoster opht

270 mmalian cells maintain the haploid state for prolonged periods, owing to the absence of competing dip

271 ct T cell alloresponses can be sustained for prolonged periods posttransplantation and result in allo

272 immunodeficiency a host can harbor virus for prolonged periods, potentially acting as a reservoir.

273 lly, despite the apparent inflammation for a prolonged period, pregnancy gingivitis rarely progresses

274 oup of the prevalent group were stable for a prolonged period prior to diagnosis.

275 of AMs/PGPRs or in plants exposed to HMs for prolonged periods, proteins guaranteeing elevated glutat

276 to sustain this anti-depressive function for prolonged periods remains unclear.

277 nparenchymal more than parenchymal cells for prolonged periods, significantly ameliorating progressio

278 tiple tumors, yet is very well tolerated for prolonged periods, suggesting that cyst(e)inase represen

279 0.003 microm2 s(-1)), as are puff sites over prolonged periods, suggesting that the architecture of t

280 hat are stored in nonacidic compartments for prolonged periods, sustained Ag presentation, and the in

281 the ventricular rate goes uncontrolled for a prolonged period, tachycardia-mediated cardiomyopathy ca

282 or oxygenation and vascular structure over a prolonged period that achieves the aim of effective vasc

283 port of the mother may be possible, even for prolonged periods, to extend the pregnancy and further f

284 ive human primary fibroblasts maintained for prolonged periods under confluence arrest.

285 nvelope protein of FrCasE bound to BiP for a prolonged period, was retained in the ER, and was degrad

286 sess the effects of MCH ablation over a more prolonged period, we monitored male and female MCH(-/-)

287 Because humans often use marijuana for prolonged periods, we examined the impact of long-term c

288 el antigen (ovalbumin) persist in a host for prolonged periods (weeks), well beyond the time at which

289 ic conditions (pH approximately 2.0-2.5) for prolonged periods, where conventional (polymer-based) bi

290 ergy expenditure and body composition over a prolonged period, which is entirely consistent with a ca

291 trongly when activated at normal rates for a prolonged period, which reduces fidelity.

292 ity to study CTCL cells and immature DCs for prolonged periods will facilitate studies of tumor cell

293 ovirus persists even in patients treated for prolonged periods with highly active antiretroviral ther

294 nlinear sensitivity to dry conditions during prolonged periods with less than 4 mm/d of precipitation

295 broblasts, and tumor cells are preserved for prolonged periods with limited host-vs-graft interferenc

296 or cells can contribute to hematopoiesis for prolonged periods, with no evidence for an effect of G-C

297 metabolic system that allows them to survive prolonged periods without oxygen by producing ethanol as

298 thesized that transfusion of RBCs stored for prolonged periods would induce adverse effects (pulmonar

299 tic connections can be stably maintained for prolonged periods, yet can be rapidly disassembled durin

300 ures of alcoholic liver disease develop over prolonged periods, yet the cellular defense mechanisms a