ライフサイエンスコーパス: promoter activity

1 g single-cell assays (immunofluorescence and promoter-activity).

2 osed for DksA in the regulation of the pArgX promoter activity.

3 increased basal IL-6 mRNA level and greater promoter activity.

4 e efficacy of LBH-589 in augmenting sGCbeta1 promoter activity.

5 riptomes are complex and formed by extensive promoter activity.

6 n of both myocardin- and Notch1-induced MLCK promoter activity.

7 how transcription factor binding impacts on promoter activity.

8 -543 is required for regulation of the mouse promoter activity.

9 Tug1 binds with the TBE to enhance Ppargc1a promoter activity.

10 P1 inhibits HIV-1 long terminal repeat (LTR) promoter activity.

11 ation of this domain reduced iron-induced C3 promoter activity.

12 xpression of integrin beta4 by targeting its promoter activity.

13 leolin binding aptamer greatly increased LTR promoter activity.

14 at-mediated HIV-1 LTR (long terminal repeat) promoter activity.

15 e of binding to TCF/LEF increased BACE1 gene promoter activity.

16 we determined the impact of STAT6 on muc5ac promoter activity.

17 ons of the HNF-1beta binding sites abolished promoter activity.

18 d in an intronic site that modulates GUCY1A3 promoter activity.

19 in differentiating IECs and stimulated CLDN7 promoter activity.

20 r expressing MKP-3 inhibited the arginase II promoter activity.

21 tes completely blocked the effect of iron on promoter activity.

22 through chromatin looping and affect MAP3K1 promoter activity.

23 s8064454 are associated with decreased HNF1B promoter activity.

24 ly member Eos, was sufficient to induce Bcl6 promoter activity.

25 d that HDAC3 expression markedly reduces Il2 promoter activity.

26 Pro1 region were found to inhibit or enhance promoter activity.

27 at beta-catenin binds to and suppresses Bmp4 promoter activity.

28 c processing causing the increase in TCF/LEF promoter activity.

29 LMW-FGF-2 and HMW-FGF-23 to stimulate FGF-23 promoter activity.

30 esulted in chromatin remodeling that reduced promoter activity.

31 tivity per se, in the inhibition of IFN-beta promoter activity.

32 ase reporter assays confirmed Gli1-dependent promoter activity.

33 r decreased IKK-induced interleukin-8 (IL-8) promoter activity.

34 cient to account for the diminished PWD CD1d promoter activity.

35 in control cells decreased PMA-induced MMP13 promoter activity.

36 abolished 17beta-estradiol-stimulated SNAT2 promoter activity.

37 ffects of Snai1 and Snai2 depletion on Nanog promoter activity.

38 ment required for butyrate induction of ALPi promoter activity.

39 rosiglitazone decreased activator protein 1 promoter activity.

40 sponse element, mutation of which attenuated promoter activity.

41 RNA and protein expression, as well as PRKCE promoter activity.

42 Sp3 differentially regulate HDAC1 and HDAC2 promoter activity.

43 acetylase 11 per se does not influence IL-12 promoter activity.

44 cose concentration-dependent effect on TRPC6 promoter activity.

45 firmed a direct impact of p38 on the IFNbeta promoter activity.

46 promoters or the bioinformatic prediction of promoter activity.

47 TTED-LIKE FROM ARABIDOPSIS THALIANA2 (KNAT2) promoter activity.

48 olytic instability, leading to reduced FXYD2 promoter activity.

49 h TNF-alpha and LPS to induce CXCL1-proximal promoter activity.

50 quired CSRP2BP for robust smooth muscle gene promoter activity.

51 s at -1018 and -57 bp) exhibited the highest promoter activity.

52 cing activity despite the lack of endogenous promoter activity.

53 eb promoter are important to Notch-dependent promoter activity.

54 expression, and promoted NF-kappaB dependent promoter activity.

55 binding and Nurr1, controlling synapsin gene promoter activity.

56 element, TA-box, in the promoter and induced promoter activity.

57 heir functional antagonism in regulating PGF promoter activity.

58 is a critical component for induction of LTR promoter activity.

59 n cardiac myocytes, which increased catalase promoter activity.

60 e levels, thus indirectly increasing Class I promoter activity.

61 ia and astrocytes exhibit detectable C9orf72 promoter activity.

62 gion is important for the regulation of CAT2 promoter activity.

63 ) pathway and promoted Sp1 to suppress EphA4 promoter activity.

64 molecules and regulates their expression and promoter activity.

65 tiate RNA synthesis, and enhancers stimulate promoter activity.

66 rachromosomal interactions with synchronized promoter activity.

67 tate receptor-dependent enhancement of COX-2 promoter activity.

68 MEP50 suppresses hINV mRNA level and promoter activity.

69 r mouse lines are based exclusively on c-fos promoter activity.

70 sequences typically encode both enhancer and promoter activities.

71 immune responses and suppression of IFNbeta-promoter activities.

72 Rather than contributing positively to promoter activity, a putative initiator element at the t

73 ide pull-down assays, revealed increased HAB promoter activity-an effect that was prevented by dexame

74 posure to salt led to a repression of PIP2;7 promoter activity and a significant decrease in PIP2;7 m

75 in more profound reduction of nonrisk allele promoter activity and a significant reduction of endogen

76 l epithelial cells, while also reducing MGMT promoter activity and abolishing MGMT induction.

77 demonstrating that CNV is regulated by both promoter activity and acetylation of histone H3 lysine 5

78 ing PAX6 and PAX4 and thus lead to increased promoter activity and ARAP1 expression in human pancreat

79 s unspliced NAT down-regulates the main LEF1 promoter activity and attenuates LEF1 mRNA transcription

80 her, ACK1 promoted calcium flux and NFAT-AP1 promoter activity and decreased the motility of murine C

81 ablishes a unique DNA-level specification of promoter activity and demonstrates predictive design of

82 UDCA treatment significantly increased SMILE promoter activity and gene expression in an adenosine mo

83 cle cells revealed a bimodal pattern of MLCK promoter activity and gene expression upon stimulation w

84 ions and siHRT2 treatments that rescued MLCK promoter activity and gene expression.

85 T cell-intrinsic tmTNF/TNFR2 stimulates Il2 promoter activity and Il2 mRNA stability.

86 s been previously found to increase the IL1B promoter activity and is the most frequent haplotype in

87 the impact of -181A-->G polymorphism on MMP7 promoter activity and its association with gastric cance

88 nhibition reduced fatty acid synthase (FASN) promoter activity and its expression.

89 knockdown of Camta1 reduced miR-212/miR-132 promoter activity and miR-212/miR-132 expression, even u

90 Mn decreases EAAT2 promoter activity and mRNA and protein levels, but the m

91 Activation of P2Y2R increased TF promoter activity and mRNA expression in HCAEC.

92 CSK9 mRNA and protein, with no effect on its promoter activity and mRNA stability.

93 Y1, 2) overexpression of YY1 decreased EAAT1 promoter activity and mRNA/protein levels, and 3) knockd

94 els, and 3) knockdown of YY1 increased EAAT1 promoter activity and mRNA/protein levels.

95 reas inhibition of NF-kappaB decreased EAAT1 promoter activity and mRNA/protein levels.

96 ates p38delta leading to increased p21(Cip1) promoter activity and p21(Cip1) mRNA/protein expression.

97 nally with RUNX2, activating tissue-specific promoter activity and prompting odontoblast differentiat

98 e novo expression of Peg3 increased Beclin 1 promoter activity and protein expression.

99 DNA binding sites are necessary for miR-150 promoter activity and that KLF2 or KLF4 overexpression i

100 We also show that TEAD can inhibit DeltaNp63 promoter activity and that TAZ can directly interact wit

101 ion of the cAMP responsive element abolished promoter activity and the binding of CREB, confirming th

102 Among these targets, NOTCH1 represses ERBB3 promoter activity and the expression of ERBB3.

103 lic adenosine monophosphate analog increased promoter activity and transcription of Hamp in cultured

104 We observed similar effects on TRPC6 promoter activity and TRPC6-dependent calcium influx.

105 STAT3 binding to the TWIST1 promoter, TWIST1 promoter activity and TWIST1 expression, reverts EMT and

106 chitecture can have a role in defining yeast promoter activity and utilize a computationally-guided a

107 We analyzed MIR122 promoter activity and validated its target mRNAs by tran

108 n of NF-kappaB binding sites decreased EAAT1 promoter activity, and 3) activation of NF-kappaB increa

109 n Tyk2-mutant mice, associated with low Tyk2 promoter activity, and leads to decreased expression of

110 expression increases p53 mRNA, protein, and promoter activity, and p53 knockdown attenuates the acti

111 mRNA expression, STAT3 phosphorylation, IL-6 promoter activity, and PPAR-delta mRNA and protein expre

112 by c-Myc/Max, USF1 and USF2, decreased hTERT promoter activity, and prevented its activation by overe

113 region, the mutation of which increased ULK1 promoter activity, and rendered it unresponsive to mTOR

114 Taken together, SM-MLCK promoter activity appears highly sensitive to the relati

115 ated TNF-alpha-mediated NF-kappaB luciferase promoter activity as a result of lowered inhibitory Ikap

116 rthermore, PA activated HAMP 3'-UTR, but not promoter, activity, as shown by reporter assays.

117 By performing a promoter activity assay and DNA binding assays, we firml

118 Using luciferase promoter activity assay combined with site-directed muta

119 By performing promoter activity assays and chromatin immunoprecipitati

120 By loss- and gain-of-function studies and promoter activity assays, we found that Jagged1/Notch1 s

121 s and measuring their expression to indicate promoter activities at single-mRNA level.

122 H2O2 stimulation increased rat OPN promoter activity at 8 and 18 h, and promoter truncation

123 plotype was determined in vitro and combined promoter activity based on both alleles (CRPA) was assig

124 smegmatis and M. tuberculosis, with maximal promoter activity being more than 2-fold that of the str

125 tivator CREBBP, and we measured enhancer and promoter activities both before and after neuronal activ

126 Importantly, factor connectivity and promoter activity both associate with perturbation size.

127 ntaining alternative haplotypes and assessed promoter activity both in vitro and in vivo using a luci

128 am binding of RNA polymerase affects the fis promoter activity both in vivo and in vitro.

129 Mutations in the -35 hexamer also influenced promoter activity but were strongly context dependent, a

130 FN reinforced Nrf2/DNA binding and increased promoter activities by enhancing expression and facilita

131 egulator of Ano1 expression, IL-4, increased promoter activity by 1.6 +/- 0.02-fold over untreated ce

132 4.7 nM) stabilized HIF-1alpha, activated HIF promoter activity by 2.5-fold, and induced HIF-target ge

133 LF14 increased basal and FGF2-stimulated SK1 promoter activity by 3-fold, and this effect was abrogat

134 30 to +25 bp of the DOC2B gene showed robust promoter activity by a luciferase reporter assay and was

135 oter was required for the induction of Smad7 promoter activity by KLF4.

136 0 in vitro, as well as the repression of AFP promoter activity by ZBTB20.

137 ven higher, because we show that dormant LTR promoter activity can rescue loss of an essential upstre

138 slows down due to nutrient limitation, rhlAB promoter activity can stop abruptly, decrease gradually

139 Consistent with their alternative promoter activity, CGI-initiated transcripts are associa

140 te the biological significance of the pol-II promoter activity clusters by investigating cluster-spec

141 f 5' UTR of the waaQ mRNA induces the rpoEP3 promoter activity concomitant with a decrease in LPS con

142 ins on BMP activity were quantified by Col X promoter activity containing the Bmp-responsive element.

143 12-myristate 13-acetate (PMA)-induced MMP13 promoter activity; conversely, Ankrd1 overexpression in

144 s in the -35 hexamer differentially affected promoter activity, depending on the -10 and extended -10

145 e upstream RNA polymerase binding on the fis promoter activity depends on the spatial arrangement of

146 y, mimicking this increase reduces the Kcna2 promoter activity, diminishes Kcna2 expression, decrease

147 Most surprisingly, promoter activity does not require either the forward or

148 veractivation of LytR led to increased lrgAB promoter activity during planktonic and biofilm growth a

149 to the TRPC6 promoter, which inhibits TRPC6 promoter activity, expression, and activity.

150 use podocytes, JAK2 knockdown decreased TFEB promoter activity, expression, and nuclear localization.

151 s quantification of transcription factor and promoter activity, followed by stochastic theoretical an

152 ays demonstrated significantly lower GUCY1A3 promoter activity for constructs carrying this allele.

153 ecreased Notch signaling, leading to reduced promoter activity for glial fibrillary acidic protein (G

154 an inference scheme, we can reverse engineer promoter activity from the bioluminescence.

155 ulation of Elk1 or Elk1 binding alters ITGB6 promoter activity, gene transcription, and alphavbeta6 i

156 nome coverage, allowing us to map autonomous promoter activity genome-wide in K562 cells.

157 rom deletion and mutation analysis of CYP2D6 promoter activity identified a KLF9 putative binding mot

158 tive mutant of human IKK2 dependent on Pdx-1 promoter activity (IKK2-CA(Pdx-1)) spontaneously develop

159 moter haplotypes that displayed differential promoter activities in neuronal cells; specifically, hap

160 Our data showed that VDR-enhances Claudin-2 promoter activity in a Cdx1 binding site-dependent manne

161 HDAC4 inhibits Runx2 promoter activity in a dosage-dependent manner.

162 omoter reporter assay showed reduced HLA-DRA promoter activity in a dose-dependent manner.

163 s a model, we show that ModH5 modulates flaA promoter activity in a GACC methylation-dependent manner

164 (0.22 < IC50 < 4.80 muM), down-regulate KRAS promoter activity in a luciferase reporter assay, and re

165 ed, Olfm2 regulated SM marker expression and promoter activity in a serum response factor (SRF)/CArG

166 I1.a and BnaC07.ABI1.b in B. napus and their promoter activity in A. thaliana showed differences in t

167 ion of OGA and correspondingly decreased OGA promoter activity in affected cells.

168 screen viral proteins for AP-1 and NF-kappaB promoter activity in AP-1- and NF-kappaB-luciferase repo

169 differences at rs1382568 resulted in altered promoter activity in B progenitor cell lines.

170 hared by FOXE1 and PTCSC2, MYH9 inhibits the promoter activity in both directions.

171 of action was ascribed to inhibition of LTR promoter activity in cells.

172 Foxf2 repressed Foxf1 promoter activity in co-transfection experiments.

173 MIR172C-D::GUS showed restricted promoter activity in galls/GCs that was regulated by aux

174 of four of these promoters confirmed strong promoter activity in GBM cells.

175 airs PPARalpha-, ChREBP-, and CREBH-mediated promoter activity in Hepa-1 cells.

176 inding, c-di-GMP levels contributed to PbrlR promoter activity in initial attached cells with elevate

177 The VNTR genotype predicts promoter activity in luciferase assays, as well as DNA m

178 Moreover, E. coli increases CD39 promoter activity in macrophages.

179 ells, and that Pro1 fragments display strong promoter activity in mature NK cell and T cell lines as

180 In contrast, HMW-FGF-2 stimulated FGF-23 promoter activity in osteoblasts through a cAMP-dependen

181 Direct measurement of FXN promoter activity in patients with expanded alleles cont

182 C/EBPbeta elements suppressed the increased promoter activity in response to activated macrophages,

183 box may play important roles in stimulating promoter activity in response to hypoxia in rice.

184 al AP-1 site all significantly suppressed TF promoter activity in response to P2Y2R activation.

185 Bioluminescence based on Saa3 promoter activity in Saa3-luc mice was promoted in obese

186 tant RXRA, demonstrating it induces enhancer/promoter activity in the context of RXRA/PPAR heterodime

187 We excluded the possibility of SCARECROW promoter activity in the mesophyll.

188 ce confirmed increased Cldn14 expression and promoter activity in the TAL of Ksp-cre;Pth1r(fl/fl) mic

189 Therefore, we analyzed the CA9 promoter activity in transfected tumor cells expressing

190 effects on transcription factor binding and promoter activity in vitro and gene expression in PBMCs

191 However, the strength of promoter activity in vitro does not correlate well with

192 changes in transcription factor binding and promoter activity in vitro.

193 d high-fidelity detection of endogenous Ins2 promoter activity in vivo, and the negative activity in

194 ibitor suberoylanilide hydroxamic acid, WIF1 promoter activity increased significantly while the over

195 RSB was silenced, C4S, versican and versican promoter activity increased, and the galectin-3 that co-

196 eals that when nutrients are abundant, rhlAB promoter activity increases gradually in a density depen

197 RUNX2 overexpression enhanced MMP13 promoter activity, independent of the MMP13 promoter met

198 was unable to increase PTH-stimulated Mmp13 promoter activity, indicating a role for the AP-1 site i

199 ild-type and mutant RET can increase the CA9 promoter activity induced by HIF-1 (but not HIF-2) in hy

200 nmt transfection significantly decreases P16 promoter activity, induces complete methylation of P16 C

201 Sad1 promoter activity is dependent on an L1 box motif, impli

202 ed to tumorigenic cells, suggesting that LTR promoter activity is dependent upon the transcriptional

203 We observe that maximum promoter activity is determined by TF concentration and

204 Specifically, we show that C9orf72 promoter activity is enriched in corticospinal and spina

205 In the absence of inducer, promoter activity is fully repressed; addition of induce

206 ell with Ly49 expression in vivo and forward promoter activity is generally weak or undetectable, sug

207 are associated with NPC risk; as well as the promoter activity is mediated by functional PIN1 variant

208 cAMP induction of SP-A promoter activity is mediated by increased phosphorylati

209 d in obese adipose tissue, showing that Saa3 promoter activity is most likely related to macrophage i

210 ether with ppGpp a severe down-regulation of promoter activity is observed.

211 lines demonstrated that both StBEL11 and -29 promoter activity is robust in leaf veins, petioles, ste

212 lines demonstrated that both StBEL11 and -29 promoter activity is robust in leaf veins, petioles, ste

213 Second, NR heterodimer-dependent promoter activity is weakened in the presence of PA in v

214 We demonstrate that C9orf72 promoter activity is widespread in both excitatory and i

215 t a gross level, the distribution of C9orf72 promoter activity largely follows overall cellular densi

216 C signaling; this led to inhibition of Gata6 promoter activity, loss of GATA6 protein, and subsequent

217 cing of ZSCAN21 increased significantly SNCA promoter activity, mRNA, and protein levels in such cult

218 accumulation is narrower than the region of promoter activity/mRNA accumulation and might serve to p

219 riptional output as well as the enhancer and promoter activities of individual elements.

220 lytic genes and overexpression decreased the promoter activities of LANA-regulated genes.

221 which might be the reason for the different promoter activities of the HAP and LAP varieties.

222 We measured the enhancer and promoter activities of thousands of DNA fragments transd

223 thermore, PsnSHN2 activated or repressed the promoter activities of transcription factors involved in

224 ponsive elements were localized by analyzing promoter activities of varying length of CYP321A1 promot

225 factor that interacts with and regulates the promoter activity of a core clock gene.

226 Here, the promoter activity of all 17 Arabidopsis TET genes was in

227 ecent experiments have shown a heterogeneous promoter activity of autoinducer synthase genes, suggest

228 erase reporter assay shows a decrease in the promoter activity of both rat and mouse genes by Pparalp

229 evealed that FOXP3 downregulates NFAT-driven promoter activity of CD40L and IL-17.

230 in IECs led to significant reductions in the promoter activity of DRA and its expression.

231 Surprisingly, the greater promoter activity of gene promoters is not due to conven

232 Consistent with the higher in vitro CHGA promoter activity of haplotype 2, individuals carrying t

233 vators of NF-kappaB (TNF and LPS), increased promoter activity of MIR122.

234 systematically analyzed the distribution of promoter activity of the mouse ortholog of C9orf72 in th

235 the in vitro methylation of CpGs reduced the promoter activity of the MTHFR regulatory region.

236 We tracked the endogenous promoter activity of the neuronal activity-regulated gen

237 However, the bidirectional promoter activity of this element may disturb expression

238 GE) time series datasets to directly measure promoter activities over time.

239 SRA inhibits ATGL promoter activity, primarily by inhibiting the otherwise

240 Also, we see a uniform decay of pseudogene promoter activity relative to their coding counterparts

241 ver, whether this stems from endogenous Ins2 promoter activity remains controversial.

242 Fine-mapping of the promoter activity revealed that two single nucleotide su

243 lexes, which can affect genetic instability, promoter activity, RNA splicing, RNA stability, and neur

244 The relative promoter activity (RPA) of each haplotype was determined

245 ese mutations were previously shown to alter promoter activity so that both replication and transcrip

246 as sufficient to block LPS-induced NF-kappaB promoter activity, suggesting alcohol-mediated immunosup

247 hat high miR-375 expression reduced vimentin promoter activity, suggesting that vimentin is an indire

248 However, gene promoters generate more promoter activity than distal enhancers, despite generat

249 Because other SVAs exhibit intrinsic promoter activity that depends in part on the hexameric

250 d virus-inducible enhancer and bidirectional promoter activity that is largely dependent on a conserv

251 r escape, helping to offset the reduction in promoter activity that would result from the weak intera

252 mone (PTH) regulates HDAC4 to control MMP-13 promoter activity through dissociation from Runx2.

253 , SHP inhibited Npas2 gene transcription and promoter activity through interaction with Rorgamma to r

254 sses DeltaNp63 mRNA, protein expression, and promoter activity through interaction with the transcrip

255 oximal FGF-23 promoter and stimulated FGF-23 promoter activity through PLCgamma/calcineurin/NFAT and

256 organ-specific gene regulation by modulating promoter activity through targeted mutagenesis.

257 oding transcription, we compared genome-wide promoter activity throughout embryogenesis in 5 Drosophi

258 gh glucose dose-dependently increased ADAM17 promoter activity, transcript, and protein levels.

259 In addition, DNA methylation reduced CYP11B1 promoter activity using a reporter assay.

260 studies and human erythroleukemia cells and promoter activity using luciferase reporter studies.

261 10 stimulated noncanonical signaling and OPN promoter activity via an upstream stimulatory factor (US

262 ANKL promoter SNP that conferred an elevated promoter activity via binding to a transcription factor

263 hich induced decay-accelerating factor (DAF) promoter activity via binding to the cAMP response eleme

264 critical for the repression of E47 and PU.1 promoter activity via Syk, Src, and the phosphatidylinos

265 EPI stimulated UGT2B7 promoter activity via this p53RE and enhanced in vivo p5

266 High-level nor promoter activity was also detectable in a cell subpopul

267 fs, the contribution of each element to CAT2 promoter activity was analyzed by site directed mutagene

268 ere cloned into reporter constructs, and the promoter activity was determined.

269 After carrageenan, GRB10 promoter activity was enhanced because of activation by

270 Arginase II promoter activity was increased by approximately 4-fold

271 CYP2C8 promoter activity was increased by ectopic expression of

272 a fragment of a wild-type promoter, whereas promoter activity was lost after site-directed mutagenes

273 DRA promoter activity was measured in a luciferase reporter

274 ITPR2 promoter activity was measured in Huh7 and HepG2 cells.

275 o both alleles in vitro, but decreased HLA-C promoter activity was observed in a luciferase reporter

276 on different promoters, as well as the same promoter activity was oppositely regulated by two differ

277 Consistent with these observations, KChIP2 promoter activity was reduced by p65 as well as beta-AR

278 Furthermore, the promoter activity was reduced considerably by in vitro m

279 Constitutive promoter activity was reduced in neurons transfected wit

280 Furthermore, DRA promoter activity was significantly increased in respons

281 PIF3 promoter activity was strongly reduced under -DIF but co

282 this gene for allantoin accumulation, AtALN promoter activity was studied using a reporter system.

283 Arginase II promoter activity was unaffected by a p38 inhibitor or J

284 A20 promoter activity was up-regulated after transfection of

285 Using PLP-EGFP mice to investigate Plp1 promoter activity, we found that, at very early time poi

286 gh promoter sequence divergence might impact promoter activity, we observed no clear link between the

287 TBA and TBAL transcripts and promoter activities were detected in developing seed coa

288 MUC5AC and muc5ac promoter activities were measured.

289 RhoA GTP binding and promoter activity were increased by Rgnef in combination

290 -repressors of YY1 to further decrease EAAT1 promoter activity, whereas inhibition of HDACs reversed

291 ntrinsically biased toward the generation of promoter activity, whereas others are not.

292 Overexpression of NRF-1 increased TDP1-promoter activity, whereas the introduction of dominant-

293 Accordingly, the promoter activity, which could phenocopy changes in Habp

294 RAS mutant increased LPS-induced arginase II promoter activity, while transfection with a vector expr

295 cell downwardly tunes CRP-dependent Class II promoter activity, whilst elevating CRP steady state lev

296 Monitoring Fpr2/3(-/-) gene promoter activity with a GFP proxy marker revealed an ov

297 p A, but not B or C, is able to modulate MYC promoter activity with a significant and dose-dependent

298 h hydrogen peroxide directly inhibited mmp-3 promoter activity with concomitant nuclear translocation

299 Hap -6A/-217A has increased promoter activity with enhanced transcription factor bin

300 We confirmed observable directional promoter activity within the 5'TR element of PB but foun