ライフサイエンスコーパス: pronucleus

1 e female pronucleus migrates toward the male pronucleus.

2 t propels the anterior migration of the male pronucleus.

3 ale pronucleus anteriorly to join the female pronucleus.

4 rces necessary to translocate and center the pronucleus.

5 e of a low level de novo H3K9me2 in the male pronucleus.

6 We show here it also positions the male pronucleus.

7 h a single centrosome detached from the male pronucleus.

8 mechanisms that regulate H3K9me2 in the male pronucleus.

9 synthesized and stored in the sea urchin egg pronucleus.

10 ind replication of DNA derived from the male pronucleus.

11 rming sperm DNA into a mitotically competent pronucleus.

12 ndle that forms in association with the male pronucleus.

13 vesicle movement) to formation of a distinct pronucleus.

14 of polar bodies and the formation of the egg pronucleus.

15 ng the early stages of migration by the male pronucleus.

16 o five times greater than that of the female pronucleus.

17 conversion of the sperm nucleus into a male pronucleus.

18 tablished around the metaphase-arrested male pronucleus.

19 e events precede the development of the male pronucleus.

20 is not inherently less than that of the male pronucleus.

21 a sperm nucleus reorganizes to become a male pronucleus.

22 ormation of the nuclear envelope of the male pronucleus.

23 on of the male pronucleus to meet the female pronucleus after fertilization requires Arp2/3.

24 GNU eggs are inseminated, however, the male pronucleus also undergoes DNA replication.

25 mic flows that are directed toward the sperm pronucleus and aggregate at the posterior cortex during

26 that CI occurs independently of the maternal pronucleus and argues against pronuclear asynchrony as t

27 al position of centrosomes, between the male pronucleus and cell cortex at the embryo posterior, is a

28 ion of cyclinE/cdk2 into the male and female pronucleus and entry into first S-phase.

29 The suSLBP is concentrated in the egg pronucleus and is released from the nucleus only when ce

30 s shortly after fertilization when the sperm pronucleus and its associated centrosomal asters provide

31 ation and posterior movement of the paternal pronucleus and its associated centrosome.

32 ronucleus or asynchrony between the paternal pronucleus and the cell cycle of the egg cytoplasm.

33 ociation must be maintained between the male pronucleus and the centrosomes during pronuclear migrati

34 hem became stably associated with the female pronucleus and the remaining cytoplasmic asters rapidly

35 in favor of DDK alleles at Om in the female pronucleus and TRD in favor of C57BL/6 alleles at Om in

36 cyclinE and cdk2 accumulation in both sperm pronucleus and zygote nucleus in vivo.

37 mpermeable eggshell, migration of the oocyte pronucleus, and the separation and expansion of the sper

38 se that robust MT nucleation pushes the male pronucleus anteriorly to join the female pronucleus.

39 s, the protein is associated with the female pronucleus at the animal pole in the unfertilized egg, b

40 (2) The newly formed pronucleus begins transcription of histone messages.

41 finding shows that Wolbachia impair the male pronucleus but no extranuclear component of the sperm.

42 gs whose normal development requires no male pronucleus but still depends on extranuclear paternal fa

43 rols both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.

44 cle (fue) is required in the zygote for male pronucleus-centrosome attachment and female pronuclear m

45 en postulated to be a component of the sperm pronucleus/centrosome complex (SPCC) as the position of

46 vanced pronuclear-stage zygotes the paternal pronucleus contains substantial amounts of 5hmC but lack

47 ein 1 beta (HP1beta) is abundant in the male pronucleus, despite the absence of di- and trimethyl H3-

48 thus ensuring the formation of a viable male pronucleus during early embryonic development.

49 achia-induced sperm modification is the male pronucleus (e.g., DNA or pronuclear proteins) or some ex

50 n, the centrosomes associated with the sperm pronucleus fail to closely associate with the posterior

51 ufficient to support polar body emission and pronucleus formation after only a single sperm-induced C

52 at inhibits nuclear transport, also prevents pronucleus formation and causes Ca(2+) oscillations that

53 ranscription is first detected shortly after pronucleus formation in 1-cell embryos, but the identity

54 A role for pronucleus formation in regulating Ca(2+) signalling is

55 nalling is demonstrated in experiments where pronucleus formation is inhibited by microinjection of a

56 Male pronucleus formation is inhibited upon deletion of Hira

57 e of a nuclear envelope and independently of pronucleus formation, is regulated by factors associated

58 As a consequence of the lack of pronucleus formation, sperm-triggered Ca(2+) spiking con

59 ately 4 hours, stopping close to the time of pronucleus formation.

60 s been associated with protecting the female pronucleus from TET3-mediated demethylation.

61 sperm entry site and trajectory of the male pronucleus in a significant majority of eggs.

62 as been reported to occur along the paternal pronucleus in fertilized oocytes in an apparently replic

63 layed nuclear envelope breakdown of the male pronucleus in Nasonia vitripennis.

64 1B is down-regulated, oocytes fail to form a pronucleus in response to Ca(2+) signals.

65 females show defective formation of the male pronucleus in vivo.

66 Further, the genome of the oocyte pronucleus, including information regarding aneuploidy a

67 In this model, a centrosome pair at the male pronucleus initiates stochastic microtubule (MT) growth.

68 Incorporation by the male pronucleus is always about four to five times greater th

69 of the sperm nucleus into a functional male pronucleus is compromised in sarah mutant eggs, indicati

70 sions: Selection and migration of the female pronucleus is independent of the sperm and its aster.

71 pecific H3 methylation reveals that the male pronucleus is negative for di- and trimethyl H3-K9 yet t

72 , the transcriptional capacity of the female pronucleus is not inherently less than that of the male

73 neither the sperm chromatin mass nor a sperm pronucleus is required for spermiogenesis, proper egg ac

74 C. elegans is specified by sperm, the sperm pronucleus itself is not required.

75 efective for the function of either the male pronucleus (mh, K81, and pal or both pronuclei (gnu, png

76 g a microtubule aster along which the female pronucleus migrates toward the male pronucleus.

77 is also observed on the surface of the male pronucleus (MPN) in vivo during NE formation.

78 rminal repeat promoter and injected into the pronucleus of fertilized oocytes of Sprague-Dawley rats

79 LEK1 protein is detected exclusively in the pronucleus of the oocyte and was not observed in other a

80 nduced the appearance of H3K9me2 in the male pronucleus of the zygote treated with cycloheximide.

81 genetic development (i.e., from the paternal pronucleus only).

82 ither a developmentally incompetent paternal pronucleus or asynchrony between the paternal pronucleus

83 ein is either in specification of the female pronucleus, or in migration of the male and female pronu

84 clear decondensation, form a functional male pronucleus, or initiate mitotic divisions in the egg.

85 s, the amount of incorporation by the female pronucleus present in parthogenetically activated eggs i

86 bolishes incorporation of H3.3 into the male pronucleus, renders the paternal genome unable to partic

87 t recruitment of lamina proteins to the male pronucleus requires, and probably accompanies, reorganiz

88 diction that the Wolbachia-modified paternal pronucleus should support androgenetic development (i.e.

89 unmethylated before it was injected into the pronucleus, so it is a good model to study the inheritan

90 s expressed in a pattern that appeared to be pronucleus-specific and maintained a nucleus-specific pa

91 with female pronuclei prior to loss in late pronucleus stage embryos.

92 of H3-K9 with DNA methylation, in the female pronucleus, suggests a mechanistically significant link.

93 iate nucleosome assembly in the nascent male pronucleus, the machinery for protamine removal remains

94 MT-length-dependent pulling forces drag the pronucleus through the cytoplasm.

95 The sperm aster then captures the female pronucleus to join the maternal and paternal genomes.

96 n one-cell embryos the migration of the male pronucleus to meet the female pronucleus after fertiliza

97 Two of these MTOCs join the female pronucleus to set up the first mitotic spindle in unfert

98 is the case in the zygote where the paternal pronucleus undergoes active DNA demethylation shortly af

99 tment of nuclear lamina proteins to the male pronucleus, we examined the subcellular localization of

100 udies emphasizing pulling forces on the male pronucleus, we propose that robust MT nucleation pushes

101 The converse is true for the maternal pronucleus, which retains 5mC but shows little or no 5hm

102 scous nuclear drag is sufficient to move the pronucleus, while simultaneously generating minus-end di