ライフサイエンスコーパス: prooxidant

1 interface to act as physical barrier against prooxidants.

2 to apoptosis induction by EGCG and classical prooxidants.

3 ate the stability of gamma-GCSh by cytotoxic prooxidants.

4 species (ChOOHs), which can act as cytotoxic prooxidants.

5 This prooxidant action of AmO was corroborated in vitro in an

6 oxidant balance in rat blood revealed a mild prooxidant activity after AmO intake, which was accompan

7 not by diphenylene iodonium, which displayed prooxidant activity and enhanced cell death).

8 Thus, vitamin E may have prooxidant activity in nonsmokers at high and prolonged

9 etermine potential sites associated with the prooxidant activity of 4HPR.

10 Thus, the prooxidant activity of Abeta leads to its own covalent m

11 , dietary fatty acids may help determine the prooxidant activity of artery wall cells.

12 Gastric juice reduced the prooxidant activity of iron ions measured as oxygen upta

13 426 because CpH426A almost completely lacked prooxidant activity whereas the other mutants expressed

14 hes to determine the site responsible for Cp prooxidant activity.

15 roduced within insects because of stress and prooxidant allelochemicals produced by host plants in re

16 stress, resulting from the imbalance between prooxidant and antioxidant states, damages DNA, proteins

17 ue reflects the state of equilibrium between prooxidant and antioxidant systems of the organism.

18 otent antioxidant; however, it can also be a prooxidant and glycate protein under certain circumstanc

19 The antioxidant, prooxidant and other mechanisms of the dietary selenium

20 ndent iron signaling are responsible for its prooxidant and proapoptotic effects and that .NO exerts

21 We used the natural prooxidant and proatherogenic molecule oxidized low-dens

22 inical outcomes in patients with CKD and has prooxidant and proinflammatory effects.

23 rity of oxidative damage due to its enhanced prooxidant and pseudoperoxidatic activities.

24 human studies on associations of individual prooxidants and antioxidants with colorectal cancer (CRC

25 ve stress, ie, an imbalance between maternal prooxidants and antioxidants, is a component of preeclam

26 sts in cells because of an imbalance between prooxidants and antioxidants.

27 s time- and dose-dependent and responsive to prooxidants and antioxidants.

28 rders are associated with elevated levels of prooxidants and declines in mitochondrial aconitase acti

29 fers resistance to the cells against several prooxidants and is suggested to reflect an adaptive resp

30 ological inhibitors (imbalances in favour of prooxidants and metalloproteinases) contributing to oxid

31 n of Nrf2 greatly enhances susceptibility to prooxidant- and carcinogen-induced experimental models o

32 x potential (RP) in blood serum reflects the prooxidant-antioxidant balance in the organism.

33 ain to be addressed in this field: (1) Which prooxidants are involved in ALD?

34 t had no effect on 17-N analogs, whereas the prooxidant ascorbic acid had the opposite effect.

35 Furthermore, the same extract exhibited prooxidant behaviour at protein level and induce formati

36 The juxtaposed antioxidant (chromanol) and prooxidant (Br-BODIPY) antagonistic chemical activities

37 d 37.5%, respectively, probably due to their prooxidant capacity.

38 to overproduction and accumulation of toxic, prooxidant compounds.

39 nt defense and detoxification capacity under prooxidant conditions.

40 holates can potentially reduce Cu(II) to the prooxidant Cu(I).

41 use only one was exposed upon removal of the prooxidant Cu.

42 Heme has prooxidant, cytotoxic, and inflammatory effects, playing

43 sults from these experiments show that under prooxidant dietary conditions, mice were able to control

44 by the antioxidant vitamin C indicating the prooxidant effect of 4HPR directly impaired mitochondria

45 thout extracts, whereas AHE extract showed a prooxidant effect on HOSO.

46 oportion, alpha-tocopherol not only exerts a prooxidant effect on soybean oil but also modifies its o

47 hibition in A431 tumor cells results in both prooxidant effects caused by the increase in the levels

48 n oxidant in several model systems where the prooxidant effects of free iron, heme, and hemoproteins

49 The anti- or prooxidant effects of green tea catechins have been impl

50 is the first to demonstrate that the noxious prooxidant effects of smoking extend beyond the epicardi

51 ver depending on the doses they also exhibit prooxidant effects.

52 398) linoleic acid peroxide (LOOH) and other prooxidants enhanced the expression of VEGF and IL-8.

53 ed the imbalance between the antioxidant and prooxidant enzymes in the corneal epithelium, followed b

54 the entire antioxidant system and important prooxidant enzymes such as nitric oxide synthase and NAD

55 ulated expression of several antioxidant and prooxidant enzymes, including glutathione peroxidase 2 a

56 luster supply to Rli1p that was defective in prooxidant-exposed cells.

57 Recent evidence suggests that chronic prooxidant exposure results in the loss of extracellular

58 representing more antioxidant exposures than prooxidant exposures, were associated with 41%-53% lower

59 a predominance of antioxidant exposures over prooxidant exposures.

60 es of dietary and nondietary antioxidant and prooxidant exposures.

61 Herein, palmitoyl ascorbate (PA) as a prooxidant for hydrogen peroxide (H2O2) production in tu

62 iverdin and bilirubin, as well as the potent prooxidant free iron.

63 Cysteinylglycine, a prooxidant generated during the catabolism of glutathion

64 orbate at pharmacologic concentrations was a prooxidant, generating hydrogen-peroxide-dependent cytot

65 product of which catalyzes breakdown of the prooxidant heme.

66 ntioxidant bilirubin, and degradation of the prooxidant heme.

67 In vitro data supports a role for prooxidants in the activation of ATP-dependent proteolyt

68 (2) What are the sources of prooxidants in the liver during alcohol exposure?

69 Furthermore, prooxidant-induced gamma-GCSh mRNA stabilization and HuR

70 cells may increase the intracellular pool of prooxidant iron prior to storage of iron within ferritin

71 1) inhibits apoptosis by regulating cellular prooxidant iron.

72 onsistent with the hypothesis that the final prooxidant is a derivative from both NO. and superoxide

73 plicons that overexpress HO-1 showed reduced prooxidant levels at baseline and increased resistance t

74 exposures (both dietary and nondietary) over prooxidant lifestyle exposures reduces risk of CRC.

75 on of an oxidant like hydrogen peroxide or a prooxidant like aminotriazole.

76 Copper, a strong prooxidant, may play a role in atherogenesis.

77 in part mediated by iron, probably through a prooxidant mechanism.

78 ioxidative mechanisms and suppressed central prooxidant mechanisms may contribute to the exercise tra

79 hat Nrf2-Keap1-dependent UGT1A1 induction by prooxidants might represent a key adaptive response to c

80 2 study of imexon (Amplimexon/NSC-714597), a prooxidant molecule, in patients with relapsed/refractor

81 pendent and associated with up-regulation of prooxidant NADPH oxidase and proangiogenic VEGF.

82 Because CoPP, unlike heme, is neither a prooxidant nor a substrate for HO-1, it might be conside

83 Polyunsaturated fat, a putative prooxidant nutrient, modified the association such that

84 effects of reperfusion-induced production of prooxidants on mitochondrial aconitase and proteolytic a

85 nstitutive activation of NF-kappaB, TNF, and prooxidant pathway in certain T cell lymphomas causes re

86 lator of apoptosis, has both antioxidant and prooxidant potential.

87 ascorbate that suggest that Abeta acts as a prooxidant producing H2O2.

88 proteolytic activity to reperfusion-induced prooxidant production appears to be a regulated event th

89 wild-type (WT) human SDHC in B9 cells caused prooxidant production, glucose consumption, sensitivity

90 The relationship between increased prooxidant production, MRPs, and HCV has not been invest

91 y increase breast cancer risk because of the prooxidant properties of iron.

92 research in recent years has uncovered their prooxidant properties.

93 These results suggest the prooxidant property of 4HPR is associated with redox met

94 a negative lifespan regulator by acting as a prooxidant protein in mitochondria; however, the regulat

95 Furthermore, prooxidant resistance was decreased by RLI1 repression a

96 beta-carotene but longer treatments made BCC prooxidant, showing that samples that underwent drastic

97 The prooxidant site was localized to a region containing His

98 Because a prooxidant state is a common feature of tumor cells, we

99 ribute to ferritin regulation in response to prooxidant stress and establish a role for ferritin in t

100 ant defense system, the sensitivity to added prooxidants such as menadione, antimycin A, H(2)O(2), an

101 nt of human colorectal cancer cells with the prooxidant sulindac increased the half-life of gamma-GCS

102 When human HepG2 cells were treated with the prooxidants tert-butylhydroquinone and beta-naphthoflavo

103 on for pursuing pharmacologic ascorbate as a prooxidant therapeutic agent in cancer and infections.

104 Most antioxidants can act as prooxidants under certain conditions, and more research

105 Paraquat, a prooxidant widely used in stress tests, had a strong ano

106 but not normal RBCs, combined with exogenous prooxidant zinc protoporphyrin (ZnPP) induce a potent tu

107 ity with dietary intakes of iron (a possible prooxidant), zinc (a possible antioxidant), and alcohol