ライフサイエンスコーパス: proper

1 essential for the development of the embryo proper.

2 rojects to a ventrolateral cluster of the Ov proper.

3 late, and piriform cortices) and hippocampus proper.

4 onset of their expression within the embryo proper.

5 11, and actin coordination are necessary for proper abscission.

6 TMEM16A is shown to be essential for proper activation and membrane expression of CFTR.

7 t ecdysteroid signaling is essential for the proper activation of matrix metalloproteinase 2 (Mmp2) f

8 gest that glutamate release is important for proper activation of the counterregulatory response to h

9 s some of the peptide catalysts to adopt the proper active conformation.

10 mployed to reduce the alveolar segments into proper alignment and to improve nasal symmetry in patien

11 Sensory processing requires proper alignment of neural maps throughout the brain.

12 d impractical to fabricate such nanowires in proper alignments by either "bottom-up" growth technique

13 ins are expressed at the proper time and the proper amount.

14 Reference region selection is important for proper amyloid PET analysis, especially in subcortical v

15 Proper analysis of sparse compositional microbiome data

16 e phenotypic transition and subsequently for proper and complete tissue regeneration.

17 stem cell can contribute both to the embryo proper and to the trophectoderm lineages in a chimaera a

18 distribution of 5-HT fibers to the amygdala (proper) and to the extended amygdala in the rat.

19 establish a feedforward loop that ensures a proper angiogenic response.

20 , together with steric interactions, ensures proper anisotropic organization of nuclear dynein forces

21 four matches identified by iMet enables the proper annotation of the unknown metabolites.

22 The role of AP-2 in the maintenance of proper apical membrane lipid and cell wall composition i

23 sure consistently outlying results; however, proper application of a follow-up analysis recommendatio

24 ial membrane composition interferes with the proper assembly and activity of mitochondrial respirator

25 Proper assembly and orientation of the bipolar mitotic s

26 the C terminus of OeGLU is essential for the proper assembly of an octameric form, a key conformation

27 RP) genes must be coordinately expressed for proper assembly of the ribosome yet the mechanisms that

28 A proper balance among quiescence, activation and differen

29 id-based electrolyzers must be guided by the proper balance between activity, stability and conductiv

30 CC development depends on the proper balance of axon growth cone attractive and repell

31 Functional SARD4 is required for proper basal immunity to the bacterial pathogen Pseudomo

32 oited the non-universality of Sec to build a proper benchmark set for tRNASec predictions, which is n

33 r results show that CM Tln2 is essential for proper beta1D-integrin expression and that Tln1 can subs

34 loprotein assembles the correct metal at the proper binding site presents challenges to the cell.

35 hese signals are thought to be essential for proper biogenesis and function of the plastid.

36 310-helix from D580 to S584 is critical for proper biogenesis of the A2 domain and FVIII, and reveal

37 Proper bone homeostasis and skeletal strength are mainta

38 tical for the development and maintenance of proper brain circuitry, and has been implicated in neuro

39 numbers and diverse types, and thus dictate proper brain development.

40 Sleep is essential for proper brain function in mammals and insects.

41 Despite FMRP importance for proper brain function, its overall expression pattern in

42 ovides evidence that ZC3H14 is essential for proper brain function.

43 that the presence of barr2 is essential for proper CAMKII function in beta-cells.

44 rentiation must be precisely coordinated for proper cardiac morphogenesis.

45 SR), a Ca storage organelle, is critical for proper cardiac muscle function.

46 NA-binding protein, are critical to maintain proper cardiac muscle function; however, the connection

47 A: There are several, technical aspects of a proper CBE.

48 maintenance of haESCs, and highlighted that proper cell cycle progression was critical for the maint

49 ng oxygen-induced DNA damage and maintaining proper cell cycle progression.

50 Cell cycle regulation is pivotal for proper cell division and cellular differentiation in euk

51 Proper cell size is essential for cellular function.

52 at division plane orientation, together with proper cell-cycle progression, is critical for plant gro

53 During ingression proper, cells leave a single-layered epithelium.

54 Histone modifiers regulate proper cellular activities in response to various enviro

55 icate protein folding process and ensure the proper cellular delivery of protein products under envir

56 o the cellular redox buffer which can impair proper cellular function.

57 tumor overexpressed gene (TOG) domain array, proper cellular localization is a requisite for full act

58 midgut epithelium in Drosophila melanogaster Proper cellular turnover and tissue function rely on tig

59 eir stability, thus having a crucial role in proper centrosome positioning, chromosomal alignment, an

60 acid residues in the GERAMT-binding site for proper chaperone-dependent regulation of SOD2 antioxidan

61 esponse of the nanoarray can be tuned by the proper choice of GNR size to overlap the fluorophore exc

62 critical for optimal yield and selectivity; proper choice of nonpolar solvent provided improved yiel

63 clic rings were also synthesized through the proper choice of the aldehyde component in the U-4CR.

64 importance of topoisomerase II activity for proper chromosome condensation and segregation during mi

65 ween homologous chromosomes is necessary for proper chromosome disjunction during meiosis I.

66 how such regulation is coordinated to ensure proper circuit development is not known.

67 Maturation of DENV particles requires proper cleavage of the viral polyprotein, including proc

68 cing systems, will be required to define the proper clinical role of these leadless systems.

69 MENT Neuronal energy levels are critical for proper CNS function, but the relative roles for the two

70 in dynamics in particular) are essential for proper cognitive function.

71 but how this activity specifically promotes proper compaction and segregation of chromosomes during

72 convergence depends on the development of a proper complement of dendritic tips and transduction pro

73 BM protein production that is essential for proper component incorporation.

74 nd, conserved kinase-independent role in the proper composition of inner kinetochore proteins.

75 purified, with the Pfs25 domain bearing the proper conformation without renaturation.

76 s required for the active site to assume the proper conformation.

77 and accurate species counts are critical for proper conservation and management.

78 With proper considerations in mind regarding the human applic

79 The safe-targeting guides allow for proper control of toxicity from on-target DNA damage.

80 pmental, and molecular events needed for the proper coordination of physiology and metabolism.

81 as an essential post-translational event for proper CoQ production.

82 Development of proper cortical circuits requires an interaction of sens

83 tes RAP80 and promotes RAP80 recruitment and proper DDR.

84 ro frequency and subsequently determined the proper degree of freedom.

85 present evidence that these cells contain a proper deletion and that the confusion is caused by DNA

86 However, due to increased model freedom, proper deployment of MCR-ALS requires careful considerat

87 histone H3 at threonine 3 (H3T3ph) promotes proper deposition of Aurora B at the inner centromere to

88 lecular motors transport organelles to their proper destinations, yet little is known about the pathw

89 This phenomenon may prove important for the proper development and functioning of tissues as well as

90 ns regulate iNKT cell fate by ensuring their proper development and maturation and by suppressing abe

91 muscle stem/progenitor cells is required for proper development and regeneration, however the signifi

92 ficiency we found that EZH2 was required for proper development of adaptive, but not innate, lymphoid

93 ction selectivity.SIGNIFICANCE STATEMENT The proper development of brain circuits and neural response

94 , we hypothesized that Irf6 is important for proper development of salivary glands and potentially ot

95 cluding the maintenance of cell identity and proper differentiation.

96 ans agree that further reform is needed, the proper direction for reform-especially following the 201

97 hape requires that cells produce forces with proper directionality.

98 Proper division plane positioning is crucial for faithfu

99 We show that MapZ is important for proper division plane selection; thus, the question rema

100 vaccines, essential cold-chain equipment, or proper documentation of vaccination activities.

101 as it enhanced Pck1 levels to interfere with proper downstream signaling to the cell integrity pathwa

102 assembly factors seipin and Fit2 to maintain proper droplet morphology.

103 y variable in clinic owing to the absence of proper drugs and the lack of understanding on the local

104 with interstitial fibrogenic cells to ensure proper ECM deposition and optimal muscle remodeling in r

105 The selection of the proper electrolyte, including solvents and salts, for LS

106 ons and cell rearrangements are critical for proper embryogenesis and organogenesis.

107 ngly, this state does not interfere with the proper encoding of tone-shock associations that eventual

108 ocation in polarizing cells is necessary for proper establishment of epithelial polarity.

109 global origin usage profile, suggesting that proper establishment of nucleosome occupancy around orig

110 These led to a proper estimation of the critical roles of volume of act

111 Proper execution of asymmetric organogenesis is critical

112 Proper execution of DDR requires careful coordination be

113 Mice lacking Erf in the embryo proper exhibited severe anemia and died around embryonic

114 f all data analysis methods that utilize the proper experimental design.

115 omponent of the podocyte slit diaphragm, and proper expression of nephrin on the cell surface is crit

116 he presence of HMGN proteins is required for proper expression of neural differentiation genes during

117 ssary for mitochondrial iron homeostasis and proper expression of several master regulators of iron m

118 cription factor, Bcl11b, is required for the proper expression of ThPOK and Runx3 and correct CD4/CD8

119 -lineage commitment factor, is essential for proper expression of ThPOK and Runx3, central regulators

120 important roles in functional axogenesis by proper extension of axon as well as the formation of AIS

121 Proper extraction and analytical methods are critical fo

122 nd also are believed to be indispensable for proper folding of gp120 and for viral infectivity.

123 direct disulfide rearrangements required for proper folding of nascent proteins synthesized in the en

124 While it evidently plays a role in the proper folding of the SPOR domain of FtsN, this domain i

125 at our analysis mainly detects selection for proper folding of the TCR receptor protein.

126 nteractions with binding partners to support proper folding.

127 um- high GI foods, not to be considered as a proper food ingredient for diabetic people and patients

128 rachlorodibenzo-p-dioxin (TCDD) prevents the proper formation of craniofacial cartilage and the heart

129 understand pharmacodynamic actions, although proper frameworks to represent drug actions are still la

130 The brain is highly sensitive to proper fuel availability as evidenced by the rapid decli

131 ost-derived IL-7 plays a role in driving the proper function of CD4+ T cells in an ACT setting remain

132 Neuronal survival is necessary for the proper function of cochlear prosthetics, therefore, it i

133 The proper function of synapses relies on efficient recyclin

134 oenvironment, including pericytes, for their proper function.

135 them, many uncertainties remain that hamper proper functional and structural data analyses.

136 Proper functioning of an organism requires cells and tis

137 els of polyunsaturated phospholipids for the proper functioning of cell membranes.

138 ion of malate to oxaloacetate as part of the proper functioning of the Krebs cycle.

139 RNA-protein interactions are essential for proper gene expression regulation, particularly in neuro

140 ance of genomic methylation patterns ensures proper gene regulation and cell behaviour, impacting nor

141 unction of the human myocardium requires the proper generation and utilization of energy and relies o

142 actively maintain DP identity and shape the proper generation of mature T cells.

143 to transduce mechanical signals and maintain proper genome organization and expression.

144 ide group between two carboxylic moieties in proper geometries, at distances less than the diameter o

145 Proper gp160 folding in the ER requires core glycosylati

146 and translational machinery required for the proper growth of the myelin sheath.

147 cytes are necessary during active growth for proper growth plate development and limb length.

148 ers in time-dependent Hamiltonians, and show proper Hamiltonian control is generally necessary to opt

149 Elderflower seasonality implies proper handling and storage conditions, for further proc

150 Proper handling of samples and data will reduce the need

151 Thus, TMEM107 is essential for proper head development, and defective TMEM107 function

152 ricians should recognize the importance of a proper history, physical examination, and general knowle

153 clusively crossovers, which are critical for proper homolog segregation in Meiosis I.

154 emic Ptch1 required for ductal outgrowth and proper hormone receptor expression in the mammary epithe

155 s been shown to be essential for maintaining proper immune homeostasis.

156 Proper inclusion of atom-exchange processes is shown to

157 eatic progenitor cell cycle is essential for proper induction of NEUROG3 and initiation of endocrine

158 coordination of synaptic connections ensures proper information flow within circuits.

159 For proper information output, higher-order chromatin struct

160 iption start site (TSS) that help direct the proper initiation of transcription.

161 nts impact on immune system remains unclear, proper integration is still a challenge.

162 brain development is necessary for mediating proper interactions between Foxp1 and the NuRD complex.

163 nfirm the importance of this interaction for proper intracellular targeting of ABCD4 and cobalamin co

164 imply not have been captured yet because the proper investigative tools are not yet readily available

165 junction assembly, but rather is needed for proper junctional actin regulation during elongation.

166 ring the functional importance of PDLIM5 for proper kAE1 membrane residency, as a crucial linker betw

167 as a regulatory phosphatase that facilitates proper kinetochore assembly.

168 A proper knowledge of the sources of (236)U is an essentia

169 The drl genes are required for proper leaf patterning, development and cell proliferati

170 omatin landscape is essential for sustaining proper leukemia cell identity and that loss of a single

171 Maintenance of proper levels of the methyl donor S-adenosylmethionine (

172 nding to forearm enhancers, thereby allowing proper limb patterning.

173 n is key to control virus infection, whereas proper limitation of signaling is essential to prevent i

174 ze the occurrence of an adverse outcome, the proper listing MELD for patients with HCC is 16, with ap

175 within the marrow space and thereby impairs proper lodgment into the niche.

176 that SlCBL10 gene is required to maintain a proper low Na(+)/Ca(2+) ratio in growing tissues allowin

177 R-155-containing exosomes is important for a proper LPS response.

178 Proper lumen morphogenesis during pancreas development i

179 of the lung alveolar in mammals is vital for proper lung function and its deficiency is related to a

180 at the ARL2-TBCD interaction is critical for proper maintenance of microtubule densities in cells.

181 The proper maintenance of potassium homeostasis is crucial f

182 Proper management of UGIB requires risk-stratification o

183 cise diagnosis is essential to guide prompt, proper management.

184 that a range of experiences can promote the proper mature expression of direction selectivity in pri

185 Thus, an early and proper melanoma diagnosis influences significantly the t

186 ntifies nerve terminals as critical sites of proper metabolic control.

187 ly when used in the residential sector, with proper methane leakage control.

188 otent anticancer property, there is still no proper method to perform the quantitative analysis of p-

189 ry constriction (MHBC), and are critical for proper MHB formation.

190 cally behave as hydrophobic if a surface has proper microstructured features.

191 AP7, but also demonstrates the importance of proper microtubule regulation in neural circuit developm

192 the Rac/Rho signaling cascade important for proper migration and differentiation of neural crest cel

193 e show that dystroglycan is critical for the proper migration, axon guidance, and dendritic stratific

194 y, which must be tightly regulated to ensure proper mitochondrial responses to intracellular Ca(2+) s

195 lized to TAN lines and was necessary for the proper mobility of EGFP-mini-nesprin-2G, a functional TA

196 wn to occur in a sequential manner to ensure proper molecular interactions, but the underlying mechan

197 he outpatient setting is essential to ensure proper monitoring and gauge the effectiveness of treatme

198 ated mesoderm migration is necessary for the proper morphogenesis and organ formation during embryoni

199 trol epithelial cell properties required for proper morphogenetic movement and pattern formation.

200 pecialized cellular microenvironment guiding proper morphology and functional behavior of specialized

201 This work demonstrates the importance of proper morphology and kinetics of ITIC --> donor polymer

202 nt inputs to the remaining regions of the Ov proper mostly arise from the NA-recipient zone of MLd.

203 D 1437, and independently confirm its age by proper-motion dating.

204 FKB-6 is required for proper movement of dynein, increasing resting time betwe

205 ny projection neurons (SPNs) is critical for proper movement.

206 Stu2 localization and thereby contributes to proper MT cytoskeletal organization in interphase and mi

207 tion of COUP-TFII expression is required for proper muscle cell differentiation.

208 caudomedial nidopallium (NCM) and HVC shelf (proper name) but not in the caudolateral nidopallium (NC

209 together, (ii) are so typical that many have proper names (e.g. Michael addition, Amadori rearrangeme

210 ights the importance of SENP8 in maintaining proper neddylation levels for CRL-dependent proteostasis

211 from radial glia progenitors is critical to proper neocortical development but the mechanisms regula

212 nitor renewal target assessed as well as for proper nephron endowment in vivo This study suggests tha

213 Proper neural circuit formation requires the precise reg

214 ood, providing a homeostatic environment for proper neural function.

215 te temporal gene expression is essential for proper neuronal and glial cell type specification.

216 Mitochondria are crucial to proper neuronal function and overall brain health.

217 attributed to its alloyed structure with the proper Ni/Cu ratio and a large number of active sites on

218 The maintenance of a proper nuclear architecture and three-dimensional organi

219 Proper oocyte development is crucial for female fertilit

220 After proper optimizations, the OSCs with DF-PCIC as the accep

221 tively difficult to access, so that only the proper orchestration of many distinct catalytic actors c

222 Copper is an essential element for proper organismal development and is involved in a range

223 Our results suggest that the proper organization of the placental labyrinth depends o

224 ions and ER-mitochondria contacts facilitate proper organization of vMIA on the OMM.

225 This leads to the proper orientation of a flexible loop proximal to the di

226 hat the folding path of twister RNA requires proper orientation of the substrate prior to T1 closure

227 ents with MS and place these findings in the proper pathobiologic and clinical context.

228 /beta-gamma transition pattern prevented the proper performance of the acquired task without affectin

229 udies have shown that NECL4 is necessary for proper peripheral nerve myelination.

230 correct subcellular locales is critical for proper physiological function.

231 , central venous catheter insertion verifies proper placement and shortens time to catheter utilizati

232 expression in late gestation is required for proper placental differentiation and function.

233 these data are significant and necessary for proper planning and interpretation of experiments.

234 lized RNA helicase that is indispensable for proper plant development.

235 the actin cytoskeleton is a prerequisite for proper platelet production and function.

236 Our results suggest that proper PM lipid composition is important to stabilize th

237 The proper positioning of mitotic spindle in the single-cell

238 s and the public regarding the importance of proper preparation of wild game prior to ingestion is wa

239 Proper pretreatment of the bonding surfaces and applicat

240 an evolutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses

241 oltage-gated sodium channels are crucial for proper propagation of the action potential through excit

242 outine dosimetry measurement of eye lens and proper protection for patients with benign lesions durin

243 For secreted proteins, proper protein folding is essential not only for biologi

244 -terminal nucleotide binding domain restored proper protein trafficking and cell surface localization

245 coordinately within mature organs to ensure proper ratios of cell types.

246 d WPB exocytosis critically depends on their proper recruitment to the plasma membrane, but factors i

247 A proper reference material is crucial for accurate measur

248 nd to environmental variation depends on the proper regulation of gene expression in an organ-, tissu

249 The proper regulation of ICOS and ICOS ligand (ICOSL) has be

250 diated axon repulsion.SIGNIFICANCE STATEMENT Proper regulation of microtubule (MT) dynamics in the gr

251 eg development and function and suggest that proper regulation of miR-27 is pivotal to safeguarding T

252 Proper regulation of osmotic balance and response to tis

253 Hence proper regulation of the abundance and activity of these

254 c loci to prevent R-loop formation, ensuring proper replication progression.

255 ranscriptional pathways is important for the proper response to DNA damage; this mechanism may be a g

256 as an RNA chaperone, folding stem IIB into a proper Rev binding conformation.

257 Thus the selection of proper ripening stage renders reduced formation of acryl

258 Proper selection of biomarkers that represent health and

259 o interconversion among metabolites) and how proper selection of quenching solvent (e.g., acidic acet

260 th experimentally and computationally that a proper selection of the substitution scheme can enhance

261 y the mir-35 family is required for not only proper sex determination but also viability, showing tha

262 actor-dependent "redoxosomes," contribute to proper signal transduction.Protein-tyrosine phosphatases

263 synaptic growth is terminated after reaching proper size remains unclear.

264 opodia and FN pillars are also necessary for proper somite morphogenesis.

265 ndodermal precursors at gastrulation and the proper specification of the neural ectoderm during neura

266 spindle pole morphology and a disruption of proper spindle orientation.

267 typed "dance," that this dance culminates in proper spindle positioning and orientation, and that com

268 tions Stu2 on the mitotic spindle to promote proper spindle structure and dynamics.

269 form may function as a checkpoint to ensure proper splicing of certain pre-mRNAs in fission yeast.

270 interrupted by introns and therefore require proper splicing to generate functional MBSs in target tr

271 hich negatively regulates Dsh, to ensure its proper stoichiometric requirement and localization durin

272 Our findings reveal that proper stomatal dynamics are built on two key properties

273 tion levels in a "goldilocks" region for the proper subnuclear storage of an SR protein splicing fact

274 220 probes and the HG-U133A array contains a proper subset (21 722 probes).

275 tes for the establishment and maintenance of proper synaptic connectivity, our understanding of their

276 Guidance of axons to their proper synaptic target sites requires spatially and temp

277 ular molecular design as well as the lack of proper synthetic methods to prepare a variety of such mo

278 coupling active transpososome assembly with proper target recruitment and discuss this model with re

279 de baseline information to better facilitate proper taxonomic assignment and minimize erroneous ident

280 in Caenorhabditis elegans, thereby ensuring proper temporal cell fate patterning.

281 Proper temporal epigenetic regulation of gene expression

282 cluding five neuronal clusters within the Ov proper, the nucleus semilunaris parovoidalis (SPO), and

283 ensuring that proteins are expressed at the proper time and the proper amount.

284 he proliferation of mutant cells to maintain proper tissue homeostasis.

285 tion and differentiation and is critical for proper tissue homeostasis.

286 y subunits (beta and alpha2delta) needed for proper trafficking and activation of the channel.

287 e hypothesize that laminins are required for proper trans-synaptic alignment.

288 R-155 expression by T cells is necessary for proper tumor-associated macrophage expression of IFNgamm

289 Proper tuning of kinetics and emission wavelengths enabl

290 he master regulator transcription factor for proper understanding of the associated disease process a

291 Proper understanding of the fundamental principles of mu

292 These results will help guide the proper use and analysis of loss-of-function reagents for

293 e SIA and remained high afterward, including proper vaccine administration techniques, proper vaccine

294 ng proper vaccine administration techniques, proper vaccine waste management, and availability of vac

295 al and clinical studies are required for the proper validation of these health promoting activities.

296 ly due to either structural requirements for proper Valpha/Vbeta association or direct contact with t

297 r domain of VIN3 plays a role in mediating a proper vernalization response in Arabidopsis.

298 ay of Hendra virus F protein is required for proper viral assembly and particle release.

299 ental windows of opportunity that ensure the proper wiring of neural circuits, as well as windows of

300 pithelialization, granulation formation, and proper wound healing in mice.