ライフサイエンスコーパス: prostaglandin F

1 ntation significantly reduced mucosal 6-keto-prostaglandin F(1 alpha) concentrations.

2 ly reduced the excretion of 2,3-dinor-6-keto prostaglandin F(1 alpha) in these animals.

3 -dinor thromboxane B(2) and 2,3-dinor-6-keto prostaglandin F(1 alpha), metabolites of thromboxane and

4 ary excretion of thromboxane B(2) and 6-keto-prostaglandin F(1)(alpha) and the ratio of the 2 compoun

5 te and nitrite (+36% versus +2%), and 6-keto-prostaglandin F(1alpha) (+71% versus +1%), whereas it de

6 ogen (BUN); thromboxane B2 (TXB2) and 6-keto prostaglandin F(1alpha) (6 kPGF(2alpha)) levels; creatin

7 ecrosis factor-alpha (TNF-alpha), and 6-keto prostaglandin F(1alpha) (6-kepto PGF(1alpha)).

8 elial cells synthesized twice as much 6-keto-prostaglandin F(1alpha) (P<0.01) and 16% less leukotrien

9 he prostacyclin metabolite 2, 3-dinor-6-keto-prostaglandin F(1alpha) (P:=0.04).

10 Immunoassays of VEGF-induced 6-keto prostaglandin F(1alpha) formation as an indicator of PGI

11 Plasma levels of nitrate and nitrite, 6-keto-prostaglandin F(1alpha), endothelin-1, asymmetrical dime

12 oxane B(2) (TXB(2)) and prostacyclin (6-keto prostaglandin F(1alpha); 6-keto PGF(1alpha)) metabolite

13 Prostaglandin F(2 alpha) (PGF(2 alpha)) receptors are G-

14 Despite structural similarity with prostaglandin F(2 alpha), the ocular hypotensive agent b

15 concentrations of an F(2)-isoprostane, 8-epi-prostaglandin F(2)(alpha) (8-epi-PGF(2)(alpha)), a bioma

16 Prostaglandin F(2)alpha (PGF(2)alpha) binding to its rec

17 tent organic nitrate administration on 8-epi prostaglandin F(2alpha) (8-epi PGF(2alpha)) content and

18 ing kidneys showed >2-fold increase in 8-iso-prostaglandin F(2alpha) (8-iso-PGF(2alpha)) levels compa

19 veloped for the measurement of urinary 8-iso-prostaglandin F(2alpha) (8-iso-PGF(2alpha)), a biomarker

20 mean changes (and 95% CIs) in urinary 8-iso-prostaglandin F(2alpha) (pg/mg creatinine) were 9.0 (-12

21 shown that stimulation of both isoforms with prostaglandin F(2alpha) (PGF(2alpha)) activates the smal

22 erential effects of two hormonal pheromones, prostaglandin F(2alpha) (PGF(2alpha)) and 17alpha,20beta

23 isoprostanes are stereo- and regioisomers of prostaglandin F(2alpha) (PGF(2alpha)) and are used as bi

24 Prostaglandin F(2alpha) (PGF(2alpha)) exerts its biologi

25 The mechanisms by which prostaglandin F(2alpha) (PGF(2alpha)) increases intracel

26 We have previously demonstrated that prostaglandin F(2alpha) (PGF(2alpha)) induces a rapid an

27 Prostaglandin F(2alpha) (PGF(2alpha)) is a potent antiad

28 As one of the major PGs, prostaglandin F(2alpha) (PGF(2alpha)) is present in huma

29 P) are G protein-coupled receptors that bind prostaglandin F(2alpha) (PGF(2alpha)), resulting in the

30 chidonic acid (AA) that are stereoisomers of prostaglandin F(2alpha) (PGF(2alpha)).

31 2)>6-keto prostaglandin F1alpha (PGF1alpha), prostaglandin F(2alpha) (PGF2alpha), and prostaglandin D

32 s G(q) in preference to G(13), whereas 8-iso-prostaglandin F(2alpha) activates G(13) in preference to

33 Prostaglandin F(2alpha) analogues are effective intraocu

34 ally, rings from remodeled LCs contracted to prostaglandin F(2alpha) and relaxed to acetylcholine in

35 actions of other neurohormones (endothelin, prostaglandin F(2alpha) angiotensin II) that also act on

36 onatal uterus was responsive to carbachol or prostaglandin F(2alpha) application; it showed a marked

37 Dietary fatty acids affect endogenous prostaglandin F(2alpha) concentrations and may thus infl

38 ntrations nor the percentage change in 8-iso-prostaglandin F(2alpha) differed significantly among tre

39 Prostaglandin F(2alpha) dose-dependently elevates blood

40 crog/mL of either latanoprost (free acid) or prostaglandin F(2alpha) ethanolamide and compared with c

41 Little is known about prostaglandin F(2alpha) in cardiovascular homeostasis.

42 exes is identified here as FPRP, the 133-kDa prostaglandin F(2alpha) receptor regulatory protein.

43 Prostaglandin F(2alpha) receptors (FP) are G protein-cou

44 ither the FP(A) or the FP(B) receptor cDNAs, prostaglandin F(2alpha) stimulates inositol phosphate ac

45 effect of these 2 vitamins on urinary 8-iso-prostaglandin F(2alpha) was observed (P = 0.12).

46 xposed to Ad.CMVeNOS, maximum contraction to prostaglandin F(2alpha) was reduced compared with viral

47 1401 U/L), blood urea (53 mg/dl), and 8-iso-prostaglandin F(2alpha), a marker of oxidative stress (3

48 ng blood glucose, and the excretion of 8-iso-prostaglandin F(2alpha), a measure of oxidative stress,

49 LC-MS/MS) method to quantify 2,3-dinor-8-iso prostaglandin F(2alpha), a urinary metabolite of 8-iso-p

50 n and quantification of different isomers of prostaglandin F(2alpha), including 8-iso-PGF(2alpha), fo

51 alpha(1)-adrenergic agonists, endothelin-1, prostaglandin F(2alpha), interleukin 1beta, and phorbol

52 Isomers of prostaglandin F(2alpha), the F(2)-isoprostanes, have eme

53 were changes from baseline in urinary 8-iso-prostaglandin F(2alpha), urinary malondialdehyde + 4-hyd

54 d urinary excretion of the isoprostane 8-iso-prostaglandin F(2alpha), which is an indicator of oxidat

55 ssure and contractile force were measured in prostaglandin F(2alpha)-constricted hearts.

56 Quantification of a group of prostaglandin F(2alpha)-like compounds derived from the

57 ose, tocotrienols and tocopherols, and 8-iso-prostaglandin F(2alpha).

58 indicated by an increase in cytosolic 8-iso prostaglandin F(2alpha).

59 (iPs) are free radical-catalyzed isomers of prostaglandin F(2alpha).

60 din F(2alpha), a urinary metabolite of 8-iso-prostaglandin F(2alpha.) Urine was purified by solid-pha

61 d receptors whose physiological activator is prostaglandin-F(2alpha) (PGF(2alpha)).

62 (protein carbonyls, oxidized LDLs, and 8-iso-prostaglandin-F(2alpha)) were measured at baseline and 6

63 fect in reducing protein carbonyls and 8-iso-prostaglandin-F(2alpha); the reductions were 6-8% and 4-

64 ncentrations of tumor necrosis factor (TNF), prostaglandin F(6-keto-PGF1 alpha), and interleukin (IL)

65 alpha that no ligand tested, including 8-iso-prostaglandin F (8-iso-PGF2alpha and a purported antagon

66 ly in the potential of the isoprostane 8-iso-prostaglandin F (8-iso-PGF2alpha), among other ligands e

67 l C(1) alkylphosphinic acid analogues of the prostaglandin-F family have been evaluated at the eight

68 e potent and selective ligands for the human prostaglandin F receptor (hFP receptor).

69 type-4 chemokine receptors, but not for the prostaglandin F receptor that cannot interact with beta-

70 le 2, potassium inwardly-rectifying channel, prostaglandin F receptor, and RXR-beta cis-11-retinoic a

71 Prostaglandin F synthase (PGFS) has dual catalytic activ

72 Prostaglandin F synthase (PGFS) was first purified from

73 We infer from the phylogenetic analysis that prostaglandin F synthase may represent a recent recruit

74 ebrate hydroxysteroid dehydrogenase enzymes, prostaglandin F synthase, and rho-crystallin of Xenopus

75 rostaglandin F synthases, such as prostamide/prostaglandin F synthase, to prostaglandin F2alpha ethan

76 ndamide may be converted by PTGS2 (COX2) and prostaglandin F synthases, such as prostamide/prostaglan