ライフサイエンスコーパス: prostaglandin G

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1 Arachidonic acid is converted to prostaglandin G(2) (PGG(2)) by the cyclooxygenase activi

2 omarkers that include arachidonic acid (AA), prostaglandin G(2) (PGG(2)), and cyclooxygenase 2 (COX-2

3 peroxide product of the PGHS-cyclooxygenase, prostaglandin G(2) (PGG(2)), by elevating the concentrat

4 alyzes the conversion of arachidonic acid to prostaglandin G(2) in the cyclooxygenase reaction.

5 mandates for arachidonic acid conversion to prostaglandin G(2) within the cyclooxygenase (COX) activ

6 lished the conversion of arachidonic acid to prostaglandin G(2), presumably because of a steric clash

7 n at C-15 to yield the endoperoxide product, prostaglandin G(2).

8 Prostaglandin G and H synthases, or cyclooxygenases (COX

9 antially higher than are required to inhibit prostaglandin G/H synthase (cyclooxygenase).

10 induced prostaglandin endoperoxide synthase, prostaglandin G/H synthase (PGHS)-2 mRNA expression and

11 The induction of prostaglandin G/H synthase (PGHS; prostaglandin endopero

12 The prostaglandin G/H synthase enzymes, commonly termed COX-

13 ct on osteoclast formation of disrupting the prostaglandin G/H synthase genes PGHS-1 and-2.

14 egans prostaglandins are synthesized without prostaglandin G/H synthase homologs, the targets of nons

15 Inhibitors selective for prostaglandin G/H synthase-2 (PGHS-2) (known colloquiall

16 igated the mechanisms by which inhibitors of prostaglandin G/H synthase-2 (PGHS-2; known colloquially

17 Prostaglandin G/H synthase-2 and zif-268 mRNA expression

18 electively elevated induction of hippocampal prostaglandin G/H synthase-2 by kainic acid correlates w

19 cid and electroconvulsive shock induction of prostaglandin G/H synthase-2 expression.

20 vated, and that kainic acid up-regulation of prostaglandin G/H synthase-2 mRNA expression in hippocam

21 ar in both seizure models, peak induction of prostaglandin G/H synthase-2 mRNA is 7-fold greater in t

22 Prostaglandin G/H synthases (PGHS), commonly referred to

23 produces a variety of prostaglandin-EA's and prostaglandin-G's nearly as diverse as those derived fro

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