ライフサイエンスコーパス: prostaglandin H2

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1 he rate of conversion of arachidonic acid to prostaglandin H2.

2 oxidase reaction reduces prostaglandin G2 to prostaglandin H2.

3 catalyze formation of an identical product, prostaglandin H2.

4 shifts the dose response curve for U46619, a prostaglandin H2 analogue, to the right.

5 9) inhibited platelet aggregation induced by prostaglandin H2 and the conversion of prostaglandin H2

6 of the cyclooxygenase-derived endoperoxide, prostaglandin H2, avidly binds to proteins.

7 Synthesis of prostaglandin H2 by prostaglandin H synthase (PHS) resul

8 The cyclooxygenase-derived endoperoxide, prostaglandin H2, can undergo rearrangement to highly re

9 e (AEA) and 2-arachidonylglycerol (2-AG), to prostaglandin-H2-ethanolamide (PGH2-EA) and -glycerol es

10 (PGHSs) 1 and 2 convert arachidonic acid to prostaglandin H2 in the committed step of prostanoid bio

11 rate of conversion from arachidonic acid to prostaglandin H2 in the PR pathway.

12 sed to determine the docking of a substrate (prostaglandin H2) mimic (U46619) to the engineered prost

13 The first COX product, prostaglandin H2 (PGH2) is also a command substrate for

14 everal prostaglandin E synthases involved in prostaglandin H2 (PGH2) metabolism.

15 the dioxygenase and peroxidase activities of prostaglandin H2 (PGH2) synthase I and II were monitored

16 for a reductase or molecular oxygen, it uses prostaglandin H2 (PGH2) to catalyze either an isomerizat

17 he formation of prostaglandin E2 (PGE2) from prostaglandin H2 (PGH2).

18 the conversion of arachidonic acid (AA) into prostaglandin H2 (PGH2).

19 However, neither a thromboxane A2/prostaglandin H2 receptor antagonist SQ29548 and a throm

20 Furthermore, SQ29548, a thromboxane A2/prostaglandin H2 receptor antagonist, significantly redu

21 -dependent PGIS nitration and thromboxane A2/prostaglandin H2 receptor stimulation.

22 OX-2) (indomethacin or celecoxib) or of TXA2/prostaglandin H2 receptors (SQ-29548).

23 The response of the inducible isoform of the prostaglandin H2 synthase (COX-2) and the c-Jun N-termin

24 Prostaglandin H2 synthase (EC 1.14.99.1) is an integral

25 looxygenase activity of the membrane protein prostaglandin H2 synthase isoform 1 (PGHS-1) is the targ

26 resolution X-ray crystal structure of ovine prostaglandin H2 synthase-1 in complex with alpha-methyl

27 Free arachidonate is converted to prostaglandin H2, the common precursor to all prostanoid

28 The conversion of exogenous prostaglandin H2 to prostaglandin E2 was only modestly i

29 these cells efficiently converted exogenous prostaglandin H2 to prostaglandin E2.

30 ed by prostaglandin H2 and the conversion of prostaglandin H2 to thromboxane A2 in intact platelets.

31 e enzyme that catalyzes the isomerization of prostaglandin H2 to thromboxane A2.

32 ificantly alter beta 2-AR and thromboxane A2/prostaglandin H2 (TP) receptor affinity.

33 c (S > > R) and antagonism at thromboxane A2/prostaglandin H2 (TP; R > > S) receptors.

34 enase-2, both metabolize arachidonic acid to prostaglandin H2, which is subsequently processed by dow

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