ライフサイエンスコーパス: proteasomal degradation

1 uently through processes that do not involve proteasomal degradation.

2 ound and target WBP2 for ubiquitin-dependent proteasomal degradation.

3 g the removal of toxic misfolded proteins by proteasomal degradation.

4 minute 2 homolog (Mdm2), which marks p53 for proteasomal degradation.

5 ase that targets CAS for ubiquitin-dependent proteasomal degradation.

6 ase, leading to RBM39 polyubiquitination and proteasomal degradation.

7 filament protein Lamin A/C protects RB from proteasomal degradation.

8 by chymotrypsin C before being directed for proteasomal degradation.

9 to protein instability of Xbp1 secondary to proteasomal degradation.

10 iated Mig6 ubiquitination and the subsequent proteasomal degradation.

11 tination in addition to serving as a tag for proteasomal degradation.

12 SOX9 and prevents it from ubiquitin-mediated proteasomal degradation.

13 innate immune system by targeting STAT2 for proteasomal degradation.

14 rects a variety of substrate fates including proteasomal degradation.

15 amma stability through the inhibition of its proteasomal degradation.

16 ets both IRF3 species for ubiquitination and proteasomal degradation.

17 ligase Hrd1 that targets BLIMP-1 protein for proteasomal degradation.

18 sor promyelocytic leukemia protein (PML) for proteasomal degradation.

19 , involves NFkappaB, and may be regulated by proteasomal degradation.

20 nteraction with Rpn8 C terminus mediates its proteasomal degradation.

21 arget IRF3 for ubiquitination and subsequent proteasomal degradation.

22 is maintained by San1 via ubiquitylation and proteasomal degradation.

23 proteins are then ubiquitinated, followed by proteasomal degradation.

24 and PA polymerase proteins, leading to their proteasomal degradation.

25 alanine protected SNAT2 against LOA-induced proteasomal degradation.

26 he tertiary stability and directly caused by proteasomal degradation.

27 llin-4 ubiquitin ligase to target SAMHD1 for proteasomal degradation.

28 -thereby preventing their ubiquitination and proteasomal degradation.

29 ream events of substrate deglycosylation and proteasomal degradation.

30 tes misfolded ER proteins to the cytosol for proteasomal degradation.

31 CRL4-DCAF1 E3 ligase for ubiquitin-dependent proteasomal degradation.

32 ate recruitment, an important step in CYP3A4 proteasomal degradation.

33 DGT catalytic sequence, was resistant to the proteasomal degradation.

34 n of lysines within this site leads to rapid proteasomal degradation.

35 ated regulation of polyamine homeostasis and proteasomal degradation.

36 iques while the protein itself is subject to proteasomal degradation.

37 eta-TrCP) E3-ligase activity in blunting Taz proteasomal degradation.

38 E3 ligase that targets specific proteins for proteasomal degradation.

39 nd that these proteins are indeed subject to proteasomal degradation.

40 y modified substrates for ubiquitination and proteasomal degradation.

41 ly regulates the abundance of TAZ protein by proteasomal degradation.

42 ogen synthase kinase 3 (GSK3) and subsequent proteasomal degradation.

43 to p21 and protects p21 from PSMA3-mediated proteasomal degradation.

44 that R-CRT dimerization may protect it from proteasomal degradation.

45 protecting PTEN from E3 ligase WWP2-mediated proteasomal degradation.

46 show that ubiquitinated CRBN is targeted for proteasomal degradation.

47 eta-catenin escapes ubiquitylation-dependent proteasomal degradation.

48 and target arrested nascent polypeptides for proteasomal degradation.

49 m the chaperone activity of Hsp90 and escape proteasomal degradation.

50 ubiquitinated proteins that are targeted for proteasomal degradation.

51 from enhanced RNF170 autoubiquitination and proteasomal degradation.

52 and appeared to be mediated through enhanced proteasomal degradation.

53 and Lp(a) was targeted for lysosomal and not proteasomal degradation.

54 cation into the cytosol, ubiquitylation, and proteasomal degradation.

55 on of substrate proteins, targeting them for proteasomal degradation.

56 lains the effects of Ubp6 on the kinetics of proteasomal degradation.

57 on has been suggested to target proteins for proteasomal degradation.

58 nd to SOX9 to inhibit its ubiquitination and proteasomal degradation.

59 anced their SUMO3 conjugation and subsequent proteasomal degradation.

60 duces HDAC3 cleavage and ubiquitin-dependent proteasomal degradation.

61 S6 (RpS6) to promote its ubiquitylation and proteasomal degradation.

62 targets unfolded/misfolded polypeptides for proteasomal degradation.

63 b modulates MCL-1 stability by affecting its proteasomal degradation.

64 the cytosolic arrival of proinsulin with its proteasomal degradation.

65 termine the susceptibility of substrates for proteasomal degradation.

66 Asi2, is polyubiquitylated and targeted for proteasomal degradation.

67 d ubiquitylation substrate of CRL3(IBTK) for proteasomal degradation.

68 uggest a model in which HUWE1 mediates DDIT4 proteasomal degradation.

69 ha and -beta were polyubiquitinated prior to proteasomal degradation.

70 em for pVHL-dependent polyubiquitination and proteasomal degradation.

71 ligase CRL4(COP1/DET1) that targets Etv5 for proteasomal degradation.

72 njugates in providing an improved signal for proteasomal degradation.

73 -inducible factor for polyubiquitination and proteasomal degradation.

74 Subsequently, Dma1 targets Vac17 for proteasomal degradation.

75 ubiquitination, which targets substrates for proteasomal degradation.

76 by interacting with them and inducing their proteasomal degradation.

77 n r (Vpr) that target and recruit SAMHD1 for proteasomal degradation.

78 s to the APOBEC3 proteins and leads to their proteasomal degradation.

79 HIV-1 Vif protein binds A3H and mediates its proteasomal degradation.

80 bilization of GABARAP, but not LC3B, through proteasomal degradation.

81 is kinase is that it is tightly regulated by proteasomal degradation.

82 -UBX-containing protein UBXN7, for efficient proteasomal degradation.

83 and (c) promoted RelA polyubiquitination and proteasomal degradation.

84 ng the inhibition exerted on alpha-synuclein proteasomal degradation.

85 vels, phosphorylating HSF1 and promoting its proteasomal degradation.

86 hat targets, e.g., the steroid receptors for proteasomal degradation.

87 in normoxia enables arginylation followed by proteasomal degradation.

88 ullin4-associated-factor 1 (DCAF1)-dependent proteasomal degradation.

89 t the transcriptional and mRNA levels and by proteasomal degradation.

90 ediated PARylation marks protein targets for proteasomal degradation.

91 on the CaV2.1 wild-type subunit via aberrant proteasomal degradation.

92 ltransferase Tip60, which targeted Foxp3 for proteasomal degradation.

93 r 152, enhancing its stability by inhibiting proteasomal degradation.

94 ors (HIFs) for ubiquitination and subsequent proteasomal degradation.

95 iquitination of proteins, targeting them for proteasomal degradation.

96 2 while decreased polyubiquitination and its proteasomal degradation.

97 duces their K48-poly-ubiquitination mediated proteasomal degradation.

98 lated A/Archipelago E3 ligase and subsequent proteasomal degradation.

99 ld-type (WT) protein expression via aberrant proteasomal degradation.

100 bosomes and targets nascent polypeptides for proteasomal degradation.

101 alpha (HIF1alpha), targeting it for eventual proteasomal degradation.

102 tinated phosphorylated TFEB, targeting it to proteasomal degradation.

103 dependent fashion without being targeted for proteasomal degradation.

104 its enzymatic activity and targeting JAK for proteasomal degradation.

105 lycomb repressive complex2 (PRC2), undergoes proteasomal degradation.

106 al isopeptide bond is not a prerequisite for proteasomal degradation, (2) by overcoming trimming at t

107 an antizyme inhibitor, ubiquitin-independent proteasomal degradation, a complex bi-directional membra

108 Formaldehyde selectively depletes BRCA2 via proteasomal degradation, a mechanism of toxicity that af

109 CR intermediate PLC-gamma1, targeting it for proteasomal degradation after TCR stimulation.

110 ction, protein aggregate formation, enhanced proteasomal degradation, altered subcellular localizatio

111 ding to BET proteins, resulting in decreased proteasomal degradation and accumulation of these protei

112 Akt-regulated USP14 activity modulates both proteasomal degradation and autophagy through controllin

113 rance pathways in the cardiomyocyte, such as proteasomal degradation and autophagy, has proven to be

114 hosphorylation of Numb leads to its enhanced proteasomal degradation and impaired Numb/p53 pathway, t

115 mediated phosphorylation protected MDM4 from proteasomal degradation and increased its protein stabil

116 at threonine 199, an event required for its proteasomal degradation and maintenance of steady-state

117 mulation, possibly because of impaired SNAI1 proteasomal degradation and nuclear translocation, might

118 HR23 proteins involved in proteasomal degradation and proteins involved in nucleoc

119 ecific cellular proteins for sumoylation and proteasomal degradation and provide significant insight

120 horylated by Pho85-Pho80, stimulated the 20S proteasomal degradation and reduced its half-life by 2.6

121 ractions protect CCM2 and CCM3 proteins from proteasomal degradation and show that both CCM2 and CCM3

122 supporting a directional preference in NQO1 proteasomal degradation and the use of ligands binding t

123 MAX2, to target SMXL/D53 family proteins for proteasomal degradation, and genetic data suggest that K

124 side its DNA binding channel, does not cause proteasomal degradation, and increases under conditions

125 TERT regulated MYC ubiquitination and proteasomal degradation, and this effect of TERT was ind

126 Proteasomal degradation appears to be mediated by ubiqui

127 nhibition destabilized AR-FL and induced its proteasomal degradation, AR-V7 protein exhibited higher

128 igations suggest that polyubiquitination and proteasomal degradation are not continuous processes but

129 for HIRA (histone cell cycle regulator) and proteasomal degradation-associated histone dynamics in t

130 able and is regulated via ubiquitin-mediated proteasomal degradation at the base of outer segments.

131 mediated endocytosis, which targets Rac1 for proteasomal degradation, becomes apparent.

132 ons prevent beta-catenin phosphorylation and proteasomal degradation but promote its nuclear accumula

133 , K301, do not only target podocin/MEC-2 for proteasomal degradation, but may also affect stability a

134 ion, the control of Vps34 ubiquitination and proteasomal degradation by FBXL20 and the associated SCF

135 onsensus VP motif of ATGL and targets it for proteasomal degradation by K-48 linked polyubiquitinatio

136 on binding a ubiquitin chain, Usp14 enhances proteasomal degradation by stimulating ATP and peptide d

137 It is targeted for proteasomal degradation by the action of a virus-specifi

138 Proteins are typically targeted for proteasomal degradation by the attachment of a polyubiqu

139 ly, SUMO chain-modified Pli1 is targeted for proteasomal degradation by the concerted action of a SUM

140 However, the light chain evades proteasomal degradation by the dominant effect of a deub

141 exes that stabilize and protect Lyn from its proteasomal degradation, contributing to toxic Lyn accum

142 ant RPE65 underwent ubiquitination-dependent proteasomal degradation due to misfolding.

143 mmonly used greenFPs can partially withstand proteasomal degradation due to the stability of the FP f

144 line (T-V) capsid mutants, designed to avoid proteasomal degradation during cellular trafficking, wer

145 on the order of FPs in the timer, incomplete proteasomal degradation either shifts the time range of

146 iggers removal of Sae2 through autophagy and proteasomal degradation, ensuring that active Sae2 is pr

147 rgo ubiquitination by the E3 ligase Ltn1 and proteasomal degradation facilitated by the ATPase Cdc48.

148 or macromolecular complexes to enable their proteasomal degradation; however, the complex nature of

149 E3 ubiquitin ligase complex and targeted for proteasomal degradation in a VCP/p97-dependent manner, w

150 HIF-1alpha polyubiquitination and consequent proteasomal degradation in an oxygen-independent manner.

151 he only pathway known to target proteins for proteasomal degradation in bacteria is pupylation, which

152 rtive intramolecular bonds that caused rapid proteasomal degradation in cells.

153 tion status to protect Topo IIalpha from the proteasomal degradation in dose- and catalytically depen

154 P35 has a short t(1/2) and undergoes rapid proteasomal degradation in its membrane-bound myristoyla

155 Mutations that inactivate proteasomal degradation in Mycobacterium tuberculosis re

156 r results show that ATXN3 rescues ITGA5 from proteasomal degradation in neurons and that polyQ expans

157 expression, and it does so by blocking HDAC4 proteasomal degradation in osteoblasts.

158 er hand, targets Dcp2 for ubiquitin-mediated proteasomal degradation in the absence of Hedls associat

159 91W RPE65 undergoes ubiquitination-dependent proteasomal degradation in the knock-in mouse RPE due to

160 elial Akt activity is transiently blocked by proteasomal degradation in the presence of SMCs during t

161 hat targets the HIF transcription factor for proteasomal degradation; inappropriate expression of HIF

162 eage packaged into virions target SAMHD1 for proteasomal degradation, increase intracellular dNTP poo

163 As Cbl-b self-ubiquitination and proteasomal degradation is impaired in Cd28(-/-) T cells

164 e ubiquitinylated, suggesting that ubiquitin-proteasomal degradation is impaired.

165 roteasomes was sparked by the discovery that proteasomal degradation is required for the pathogenesis

166 nts DNA re-replication by targeting CDC6 for proteasomal degradation late in the cell cycle.

167 sor, which targets the HIF-alpha subunit for proteasomal degradation, led to rapid development of hyp

168 s a signal to promote its ubiquitination and proteasomal degradation mediated by FBXL20 (an F-box pro

169 uently been hypothesized that ubiquitin-like proteasomal degradation might also operate in these micr

170 by inhibiting host cell transcription and by proteasomal degradation of a major antiviral IFN effecto

171 rganogenesis, accelerated ubiquitin-directed proteasomal degradation of a master transcription factor

172 iggered terminal myeloid differentiation via proteasomal degradation of A/E9a.

173 tingly, LDAH enhances polyubiquitination and proteasomal degradation of adipose triglyceride lipase (

174 necessary and sufficient for CUL5-dependent proteasomal degradation of all members of the B56 family

175 lular phenotype is associated with increased proteasomal degradation of alpha5 integrin subunit (ITGA

176 on state of CaMKII and the agonist-triggered proteasomal degradation of AMPARs during memory consolid

177 ated nuclear translocation of AR and induced proteasomal degradation of AR and ARV, suppressing the t

178 p2 and Ubp15 prevent hyperubiquitination and proteasomal degradation of ARTs.

179 SIAH proteins promote the ubiquitination and proteasomal degradation of Axin through interacting with

180 SPOP binds to and induces ubiquitination and proteasomal degradation of BET proteins (BRD2, BRD3 and

181 This effect could not be explained by proteasomal degradation of Bim or bim promoter inhibitio

182 Increased proteasomal degradation of BMPRII appears to underlie th

183 levant mouse model associated with increased proteasomal degradation of BMPRII.

184 N-methyl-D-aspartate receptors promoted the proteasomal degradation of BRCA1.

185 a key factor that facilitates the ubiquitin-proteasomal degradation of c-Myc protein, as knockdown o

186 Rescue of KLHL9 expression induced proteasomal degradation of C/EBP proteins, abrogated the

187 p42 for the K48-specific ubiquitin-dependent proteasomal degradation of C/EBPalpha p42.

188 fully reversing EA2 mutant-induced excessive proteasomal degradation of CaV2.1 WT subunits.

189 otal role in the cell cycle by mediating the proteasomal degradation of Cdt1 (DNA replication licensi

190 ge event that is independent of the cellular proteasomal degradation of CIDEB.

191 ease-causing mutant A531V manifests enhanced proteasomal degradation of CLC-1.

192 Arginylation was not required for proteasomal degradation of CRT, although R-CRT displays

193 nd Ubp3 deubiquitinases are required for the proteasomal degradation of cytosolic misfolded proteins

194 duct inhibition, cholesterol accelerates the proteasomal degradation of DHCR7, resulting in decreased

195 elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1, a hos

196 E6AP promotes ubiquitination and proteasomal degradation of ECT2 for which high expressio

197 uces PKA phosphorylation, ubiquitination and proteasomal degradation of eENT1.

198 eat shock protein 90 (HSP90) and followed by proteasomal degradation of EZH2 in drug-resistant cells.

199 We demonstrate that polyubiquitination and proteasomal degradation of ezrin and CUGBP1 require Uba6

200 of FoxM1b facilitates the ubiquitin-mediated proteasomal degradation of FoxM1b.

201 ptide and ester bond ubiquitination regulate proteasomal degradation of hD4R.

202 Under calcification-inducing conditions, proteasomal degradation of HDAC1 precedes VC and it is m

203 anistically, PYK2 inhibition facilitated the proteasomal degradation of HER3 while inducing upregulat

204 in Absentia Homolog1 (SIAH1), which mediates proteasomal degradation of HIPK2, was decreased in the g

205 tor of the Cul4A ubiquitin ligase to trigger proteasomal degradation of HLTF.

206 ect of PCSK9 regulation by ubiquitin-induced proteasomal degradation of HNF1alpha.

207 Proteasomal degradation of HOIP leads to irreversible in

208 his ubiquitin-editing process results in the proteasomal degradation of Imd, which we propose functio

209 Fourth, PA inhibited lysosomal and proteasomal degradation of internalized EGFR.

210 quitylation, a process that does not lead to proteasomal degradation of its substrates.

211 is regulated by VprBP, but Vpr enhances the proteasomal degradation of MCM10 by interacting with Vpr

212 of Vpr to MCM10 enhanced ubiquitination and proteasomal degradation of MCM10.

213 out selectively inhibited ubiquitination and proteasomal degradation of MiD49, a mitochondrial recept

214 ibuted to mRNA down-regulation and the rapid proteasomal degradation of MOAP-1 that could be reversed

215 A or arsenic trioxide synergistically induce proteasomal degradation of mutant NPM1 in AML cell lines

216 rate that gigaxonin is crucial for ubiquitin-proteasomal degradation of neuronal IF.

217 sphorylation, ubiquitination, and subsequent proteasomal degradation of NF-kappaB subunits.

218 pon induction by phospho-Ser64-Skp2-mediated proteasomal degradation of Nkx3-1, participated in ER tr

219 otein, which mediates the ubiquitination and proteasomal degradation of Nrf2, has a strong protective

220 tion in cancer cells leads to SIRT1-mediated proteasomal degradation of oncogenic transcription facto

221 riggers ubiquitination, internalization, and proteasomal degradation of P-gp.

222 quitin ligase well known for its role in the proteasomal degradation of p53 in human papillomavirus (

223 Here, Mid1 regulates the ubiquitination and proteasomal degradation of Pax6 protein.

224 the 148M variant disrupts ubiquitylation and proteasomal degradation of PNPLA3, resulting in accumula

225 tritional virulence factor and promotes host proteasomal degradation of polyubiquitinated proteins ge

226 es posttranslational mechanisms that prevent proteasomal degradation of proto-oncogene beta-catenin (

227 stone H4 knockdown cells was associated with proteasomal degradation of RIP1, accumulation of cellula

228 ity was required to promote the K48-mediated proteasomal degradation of Rsp5 HS-induced substrates.

229 rentiation by suppressing the AMPK-dependent proteasomal degradation of Runx2 and promotes bone forma

230 of the virus into the cytoplasm, induce the proteasomal degradation of SAMHD1.

231 Although Hsp104 is absolutely required for proteasomal degradation of Sdj1-L169P aggregates, the de

232 the functions of gigaxonin is to facilitate proteasomal degradation of several IF proteins, we sough

233 other species of phytoplasma can trigger the proteasomal degradation of several MADS box transcriptio

234 lphabeta regulatory particle, which enhances proteasomal degradation of small peptides and unfolded p

235 nation of SMN has a mild effect on promoting proteasomal degradation of SMN.

236 ligase Rkr1/Ltn1 has been implicated in the proteasomal degradation of soluble cytosolic nonstop and

237 of multiple cellular proteins and subsequent proteasomal degradation of some of them, but the detaile

238 ntified the viral protein pM27 as inducer of proteasomal degradation of STAT2.

239 y inhibiting BMI-1/RING1B-mediated ubiquitin-proteasomal degradation of SUMO1/sentrin-specific protea

240 Fbxl7 mediates polyubiquitylation and proteasomal degradation of survivin by interacting with

241 mechanistically by showing that Plk1 induces proteasomal degradation of SUZ12 and ZNF198 by site-spec

242 Ubiquitination-directed proteasomal degradation of synaptic proteins, presumably

243 esulting in increased polyubiquitination and proteasomal degradation of TAP1.

244 peat-containing proteins (betaTRCP) mediated proteasomal degradation of TAZ, as well as a correspondi

245 thelial cells lacking PCBP2 exhibit impaired proteasomal degradation of TAZ.

246 ubiquitin ligase promotes ubiquitination and proteasomal degradation of TDG in S phase in a reaction

247 A major virulence mechanism is the proteasomal degradation of the antiviral kinase PKR by t

248 s susceptibility in macrophages by promoting proteasomal degradation of the cell survival protein Bcl

249 whereas AICAR blocked the cell cycle through proteasomal degradation of the G2M phosphatase cdc25c.

250 ZIKV NS5 expression resulted in proteasomal degradation of the IFN-regulated transcripti

251 ion led to elevated ubiquitination and rapid proteasomal degradation of the PAX3-FOXO1 chimeric oncop

252 Jnk2 promoted ubiquitination and proteasomal degradation of the small mitochondrial form

253 protein, PROTACs promote ubiquitination and proteasomal degradation of the target protein.

254 ently enhanced ubiquitination and subsequent proteasomal degradation of the wild-type CaV1.2 channels

255 ave been described, the mechanism leading to proteasomal degradation of these defective translation p

256 ) E3 ubiquitin ligases leading to subsequent proteasomal degradation of these substrates.

257 Subsequent proteasomal degradation of these transcription factors k

258 CS1 nuclear translocation but independent of proteasomal degradation of transcription factors.

259 F box E3 ligase subunit, thereby alleviating proteasomal degradation of TRF1, leading to a stable ass

260 lized Twist protein expression by preventing proteasomal degradation of Twist by beta-TrCP.

261 ere cyclin F mediates the ubiquitination and proteasomal degradation of Vif through physical interact

262 in complexes into the cytosol, and increased proteasomal degradation of wild-type cavin1 but not muta

263 with KIN10 abrogates this effect by inducing proteasomal degradation of WRI1.

264 Caffeine treatment led to the rapid loss, by proteasomal degradation, of both Sae2, a nuclease that p

265 se to TGF-beta treatment is mediated via the proteasomal degradation pathway.

266 ual regulation of protein levels through the proteasomal degradation pathway.

267 G132, indicating that both the lysosomal and proteasomal degradation pathways are involved.

268 oper MAF phosphorylation, ubiquitination and proteasomal degradation, perturbed gene expression in pr

269 C3 also flagged viruses for rapid proteasomal degradation, preventing their replication.

270 TAP shuttles proteasomal degradation products into the lumen of the e

271 lines, the variant SRY exhibited accelerated proteasomal degradation (relative to wild type) associat

272 ins may be targeted to ubiquitin-independent proteasomal degradation remains unclear.

273 This enhanced proteasomal degradation required protein ubiquitination,

274 at exhibited decreases in ubiquitylation and proteasomal degradation resulting from heteromeric compl

275 lein degradation along with the promotion of proteasomal degradation, resulting in aggregate clearanc

276 e we report that tagging Cas9 with ubiquitin-proteasomal degradation signals can facilitate the degra

277 and targeted it for ubiquitination-mediated proteasomal degradation, terminating IL-4 or IL-13 signa

278 ed Parkin in the regulation of mitophagy and proteasomal degradation, the precise mechanism leading t

279 tion, reduce PEX5 abundance by promoting its proteasomal degradation, thereby impairing its functions

280 iated phosphorylation coupled with ubiquitin-proteasomal degradation, thereby prolonging its accumula

281 misfolded collagen X by either autophagy or proteasomal degradation, thereby reducing intracellular

282 cally, WSB1 promotes pVHL ubiquitination and proteasomal degradation, thereby stabilizing HIF under b

283 dent PPARgamma activation is associated with proteasomal degradation; therefore, regulation of PPARga

284 the N-terminal domain (NTD) and accelerating proteasomal degradation through dynamic effects on the C

285 ts the partially synthesized polypeptide for proteasomal degradation through the action of the ubiqui

286 yltransferase, CHROMOMETHYLASE 3 (CMT3), for proteasomal degradation to initiate destabilization of t

287 pVHL (von Hippel-Lindau protein) followed by proteasomal degradation under normal conditions.

288 ation of its triphosphohydrolase activity or proteasomal degradation using specialized, virus-like pa

289 at Nrf2 is regulated at the protein level by proteasomal degradation via Kelch-like ECH-associated pr

290 use its N-terminal tryptophan targets it for proteasomal degradation via the N-end rule pathway.

291 The 20S proteasomal degradation was conserved for human lipin 1

292 in the absence of CaVbeta subunits even when proteasomal degradation was inhibited with MG132 or ubiq

293 , the path from the CUL3 complex to ultimate proteasomal degradation was previously unknown.

294 Proteasomal degradation was quantified by measuring chym

295 SM undergoes cholesterol-dependent proteasomal degradation when cholesterol is in excess.

296 eat-induced Rsp5 substrates are destined for proteasomal degradation, whereas other Rsp5 quality cont

297 utophagy inactivation redirects HIF2alpha to proteasomal degradation, whereas proteasome inhibition i

298 fenib down-regulated total FAK, inducing its proteasomal degradation, while Ln-332 and HSC-CM promote

299 ting the human CaV2.1 subunit from excessive proteasomal degradation with specific interruption of en

300 in gene transcription coupled with impaired proteasomal degradation, yet this hypothesis remains unt