ライフサイエンスコーパス: protect against

1 icit immune responses that are able to cross-protect against a significant fraction of the diverse vi

2 In addition, it is protected against a cold challenge and high-fat diet (HF

3 ive VACV-specific CD8(+) T cell response and protected against a lethal VACV challenge.

4 These mice were protected against a lethal-dose toxin challenge, but Ty2

5 A vaccine that protects against a broad range of New World arenaviruses

6 Thus, TET2 indeed may protect against abnormal, cancer DNAm in a manner linked

7 ndividuals exhibit cognitive resilience that protects against AD dementia.

8 However, NOD-Idd22 mice were highly protected against adoptive transfer of T1D.

9 Runx1-deficient mice were protected against adverse cardiac remodeling after MI, m

10 unction, assessed by echocardiography, while protecting against adverse cardiac remodeling and apopto

11 dose for alleviating radiation injury while protecting against adverse effects reveals a viable radi

12 ing that GHR inhibition has the potential to protect against age-dependent cognitive decline.

13 ptor deficiency (GHRD or Laron syndrome) are protected against age-related diseases including cancer

14 vity maintained glucose homeostasis and were protected against age-related obesity and insulin resist

15 er telomeres relative to humans, potentially protecting against age-related disease caused by haploin

16 sized that specific calpain inhibition would protect against aging-related lesions in arteries and ki

17 We found that TSG-6 deficiency protects against AHR after ozone (in vivo) or sHA (in vi

18 Impella 2.5 (pLVAD) support protected against AKI during high-risk PCI.

19 la 2.5 microaxial pLVAD during high-risk PCI protected against AKI.

20 idneys, and genetic deletion of Rac1 in SMCs protected against AKI.

21 d applicable preconditioning intervention to protect against ALF; autophagy and JNK may also provide

22 ization with a hypoallergenic Cyp c 1 mutant protect against allergic reactions in a murine model of

23 allergenic mutant of the major carp allergen protect against allergic symptoms in sensitized mice.

24 responses toward environmental allergens and protecting against allergic diseases.

25 HDM engagement with PC receptors in the lung protects against allergic airway disease.

26 STN DBS did not protect against alpha-syn-mediated deficits in forelimb

27 Human homologs of top-ranked hits protected against alphaSyn-induced cell death in a human

28 ro and in vivo, the data show that nnAbs can protect against and alter the course of HIV-1 infection

29 increasing angiogenesis and cell survival to protect against and limit damage associated with the pro

30 y as a promising new therapeutic strategy to protect against anticancer drug-induced peripheral neuro

31 proteases, we considered that C1 could help protect against antinuclear autoimmunity by broadly degr

32 Estrogens protect against apoptosis of endothelial cells (ECs), on

33 by these proteins in either facilitating or protecting against apoptosis is unclear.

34 d#1 vaccine strain of Junin virus is used to protect against Argentine hemorrhagic fever.

35 aMV-induced virus factory inclusions seem to protect against autophagic destruction by sequestering c

36 creases NMN levels by converting it to NaMN, protects against axon degeneration.

37 set of gapless states that are topologically protected against backscattering.

38 PGA2 enhanced the EC barrier and protected against barrier dysfunction caused by vasoacti

39 and IL-17A knockout (il17a(-/-) ) mice were protected against bleomycin (BLEO)-induced fibrosis and

40 Moreover, T63 markedly protected against bone mass loss in the ovariectomized a

41 ing evidence in nonhuman primates that BPZE1 protects against both pertussis disease and B. pertussis

42 e results suggest LIP ultrasound stimulation protects against brain injury in the hippocampus and cor

43 neutralize TcdB function have been shown to protect against C. difficile infection in animal models

44 in interactions, the modulation of which may protect against cancer, radiation, and aging.

45 hanism by which heart rate variability could protect against cardiac arrhythmia.

46 IF1 knockout (KO) mice were protected against cardiac dysfunction and pathological d

47 er, overexpression of DLST in wild-type mice protected against cardiac hypertrophy and dysfunction in

48 roxytyrosol-related foods have been shown to protect against cardiovascular disease (CVD).We investig

49 hat the use of arginine in dentifrices helps protect against caries.

50 s oligodendrocyte mitochondrial function and protects against caspase-dependent oligodendrocyte apopt

51 nd for five outcomes, with male circumcision protecting against cervical cancer, cervical dysplasia,

52 e, suggest that early-life farming exposures protect against childhood asthma and allergy; few data e

53 While vaccines protecting against cholera exist, and oral rehydration t

54 Here we report that SORT1 deficiency protected against cholesterol accumulation-induced liver

55 To test how caspase-2 protects against chromosomal instability, we utilized an

56 cing alpha-mannosidase-like proteins (EDEMs) protected against chronic ER proteinopathy without induc

57 oreover, Hdac6 deficient mice were partially protected against chronic hypoxia-induced pulmonary hype

58 INTERPRETATION: Sodium thiosulfate protects against cisplatin-induced hearing loss in child

59 on exacerbates, whereas MIOX gene disruption protects against, cisplatin-induced AKI.

60 ses revealed that ITNs did not significantly protect against clinical malaria (odds ratio [OR]=0.95,

61 g Ca(2+) levels in the afferent terminal may protect against cochlear synaptopathy associated with he

62 rticulturalists (N = 372) to test whether E4 protects against cognitive decline in environments with

63 nflammation in the intestine, where it helps protects against colitis-associated cancer by regulating

64 While Th17 cells can protect against colonization by pathogenic organisms, th

65 important roles in sensing the environment, protecting against colonization and infection of pathoge

66 The tick IMD network protects against colonization by three distinct bacteria

67 tion of local complement proteins that could protect against complement-mediated damage.

68 nd Rad2/XPG nucleases were also important in protecting against contractions, but through BER rather

69 loroquine prophylaxis (PfSPZ-CVac), and were protected against controlled human malaria infection.

70 Metformin may protect against coronary atherosclerosis in prediabetes

71 zygous deficiency of APOC3 has been shown to protect against coronary heart disease; we identified AP

72 sistance of blood cells could be critical in protecting against cross-species infection.

73 Overexpression of SPL protected against cytokine toxicity.

74 SPL-overexpressing cells were partially protected against cytokine-mediated ATP reduction and in

75 Here, we determined that chymase protects against cytokine-enhanced bronchoconstriction b

76 causing familial Alzheimer's disease (AD) or protecting against dementia.

77 Farm exposure protects against development of allergies early in life.

78 Maternal folic acid (FA) protects against developmental toxicity from certain env

79 the hypothesis that, knockout of cathepsin K protects against diabetes-associated cardiac anomalies.

80 How metformin protects against diabetes-related cardiovascular disease

81 indings suggest a novel role for miR-146a in protecting against diabetic glomerulopathy and podocyte

82 cytokine IL-10 improves insulin sensitivity, protects against diet-induced obesity, and elicits the b

83 w that hepatocyte-specific deletion of c-Fos protects against diethylnitrosamine (DEN)-induced HCCs,

84 rulent B. pertussis isolate, they were fully protected against disease, whereas naive baboons develop

85 failure, whereas genetic deletion of Il11ra1 protects against disease.

86 d into a layer of photosensitive dye that is protected against dissolution into the LCLC by a liquid

87 Thus, PKM2 activation may protect against DN by increasing glucose metabolic flux,

88 We find that Gata6 protects against DNA damage associated with proliferatio

89 e anti-O2 specific antibody, synergistically protect against drug-resistant strains in adjunctive the

90 Loss of Ccdc88b protects against DSS-induced colitis, with fewer patholo

91 r platelet-specific deficiency in CLEC-2 are protected against DVT.

92 A and AMP-activated protein kinase (AMPK) to protect against DXR in part by activating the mammalian

93 ggests delayed introduction of egg might not protect against egg allergy in infants at risk of allerg

94 Conversely, laminar flow protects against endothelial dysfunction, at least in th

95 of biopharmaceuticals to human serum albumin protects against enzymatic degradation and renal clearan

96 e, upregulation of EDEM function in the ERAD protects against ER proteinopathy in vivo and thus repre

97 th surfaces, acquired enamel pellicle (AEP), protects against erosive wear.

98 Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degenerat

99 nutritional and insulin dose adjustments to protect against exercise-related glucose excursions.

100 reg cells (Act-A-iTreg cell-modified DCs) to protect against experimental asthma, and the mechanisms

101 ce for stormwater reuse are not adequate for protecting against exposure to Campylobacter.

102 atment with exogenous interleukin 12 (IL-12) protects against F. tularensis infection; this protectio

103 t, the pancaspase inhibitor zVAD-fmk did not protect against FA-AKI.

104 Double knockout mice were protected against fasting-induced hepatic steatosis (a m

105 demonstrate that liver-specific Shp deletion protects against fatty liver development by suppressing

106 ion acquisition in BL6 mice, and furthermore protected against fear renewal in BL6 mice.

107 on a druggable lipid-peroxidase pathway that protects against ferroptosis, a non-apoptotic form of ce

108 KV burden in maternal and fetal tissues, and protected against fetal demise.

109 uring homeostasis, but are also effective in protecting against FFA-induced oxidative stress; thus, E

110 of HA inhibition (HI) titers, but failed to protect against five different heterologous lethal influ

111 week (OR, 0.21; 95% CI, 0.08-0.58; P = .003) protected against gastrointestinal AEs more than once-we

112 Quantum error correction can protect against general noise if-and only if-the error i

113 cell population cooperates with antibody to protect against genital chlamydia and establish neutroph

114 Thus, the LPAR antagonist BMS002 protects against GFR decline and attenuates development

115 GOT mRNA and protein expression at 24 h and protected against glutamate-induced cell death.

116 rotransmitter, its concentration drops, thus protecting against glutamate-induced excitotoxic stress.

117 that nTregs are essential for AzaC to fully protect against GvHD and have important clinical implica

118 red in the donor graft for AzaC to optimally protect against GvHD and that nTregs, unlike Teffs (CD3(

119 hese data suggest that maraviroc effectively protects against GVHD by modulating alloreactive donor T

120 ation of such immunosuppressive therapies to protect against HBV reactivation.

121 ting Ca(2+) accumulation in the terminal may protect against hearing loss.

122 manner 1 week before a stressor, in order to protect against heightened fear responses to aversive st

123 Hemopexin protects against heme toxicity in hemolytic diseases and

124 ified alpha-cedrene, a natural compound that protects against hepatic steatosis in mice fed the high-

125 MiR-204-I protected against HFD-induced downregulation of endothel

126 ompanied by persistent beneficial effects in protecting against HFD-induced obesity and metabolic dis

127 Furthermore, Nox2-deficient mice are protected against high-fat diet-induced hepatic steatosi

128 adjuvanted Env protein boost is critical for protecting against high-dose SIVsmE660 challenge and for

129 ing regarding the efficacy of alendronate to protect against hip fracture in older patients using glu

130 or its interaction with histones but also to protect against histone-induced cell death.

131 d ocular pathology, yet the ability of Ab to protect against HSV-1 is deemed limited due to the slow

132 Falpha-treated PAEC with CHC (100 microg/ml) protected against human plasma-induced endothelial activ

133 ncy evidence was found for male circumcision protecting against human papillomavirus and low-risk hum

134 n and Tat-Beclin-1 increased ureagenesis and protected against hyperammonemia in a variety of acute a

135 SGE-516 treatment protected against hyperthermia-induced seizures, reduced

136 Depletion of neutrophils protected against hypothermia and mortality.

137 pac1 in its mitochondrial-targeting sequence protects against hypoxia/reoxygenation-induced cell deat

138 n variants of the IL23-receptor gene (IL23R) protect against IBD, and, in animals, blocking IL23 redu

139 Adaptive immune responses protect against infection with dengue virus (DENV), yet

140 iNKT cells) are innate-like lymphocytes that protect against infection, autoimmune disease and cancer

141 However, anti-HA protects against infection in humanized mice and strongl

142 challenge with B. mallei ATCC 23344, it also protects against infection with multiple isolates of the

143 e (EW) provides nutrition for the embryo and protects against infection, with glycosylation responsib

144 actor 3 (IRF3) and type I interferons (IFNs) protect against infections and cancer, but excessive IRF

145 ibodies contribute to tissue homeostasis and protect against infections.

146 The innate immune system protects against infections by initiating an inducible i

147 Calpains inhibition protects against inflammaging, limiting kidney and vascu

148 vaccination is a viable strategy to broadly protect against influenza B virus infection.IMPORTANCE W

149 Its capacity to protect against initial enamel erosion was also tested i

150 ls are elevated after renal ischemia and may protect against injury.

151 entation with omega 3 long-chain fatty acids protect against intestinal inflammation.

152 Furthermore, we have shown that CAMK2gamma protects against intestine tissue injury by increasing I

153 Commensal bacteria protect against invading pathogens using many strategies

154 On the other hand, AHAs may protect against invasive microbial pathogens and cancer.

155 t of pneumococcal conjugate vaccine (PCV) in protecting against invasive pneumococcal disease (IPD) c

156 te lymphoid cells, and possibly Foxp3+ Tregs protect against IR through local control of inflammation

157 ance, preventing permeability transition and protecting against ischaemia-induced cardiomyocyte necro

158 rate usage and mitochondrial uncoupling, and protects against ischaemia/reperfusion.

159 ncreased gamma2-AMPK activity is required to protect against ischemia/reperfusion injury.

160 educed renal levels of hypusinated eIF5A and protected against ischemia-reperfusion-induced renal inj

161 that vitamin D3 produced in the skin by UVR protects against its oncogenic effects by inhibiting Hed

162 yD88 signaling by an IRAK4 inhibitor in vivo protected against kidney injury by profoundly attenuatin

163 ble potency compared to bioprocessed IgG and protect against lethal pneumonia in mice.

164 tasigH, a stress-response-attenuated strain, protected against lethal TB in macaques.

165 ng IgG responses to an extent that mice were protected against lethal virus infection.

166 -B10 antibody given 3 d after ZIKV infection protected against lethality, reduced ZIKV levels in brai

167 cells, prevented microbiota encroachment and protected against LGI and metabolic syndrome.

168 amyloid protein precursor-knockout mice were protected against lithium-induced iron elevation and neu

169 ctivity seems to preserve lung volume and to protect against lung collapse.

170 IPTp-SP appears to protect against malaria, STIs/RTIs, and other unspecifie

171 enormous promise as vaccines to prevent and protect against many infectious and noninfectious diseas

172 Thus, fermentable fiber protects against metabolic syndrome by nourishing microb

173 hile 20-30 bp of the binding site itself are protected against methylation.

174 Transgenic mice expressing hCD55 alone were protected against mild renal IRI, with reduced creatinin

175 o which tissues within the same organism are protected against mitochondrial damage.

176 ent quantities of manganese (Mn) but also in protecting against Mn toxicity.

177 a infection, sunitinib/erlotinib combination protected against morbidity and mortality.

178 phrenia alleles to identify novel mechanisms protecting against more rapid cognitive decline and psyc

179 nfected with EW murine RV were substantially protected against mortality following parenteral endotox

180 of maternal humoral responses that partially protect against MTCT of HIV is required to inform the de

181 onectin maintains intestinal homeostasis and protects against murine colitis through interactions wit

182 underlie sex-related differences in FSHD by protecting against myoblast differentiation impairments

183 okine signaling-1 (SOCS1) regulatory protein protects against nephropathy by suppressing STAT-mediate

184 Emerging evidence shows that FTY720 protects against neural injury via modulation of the sph

185 al excitability, cortical lamination, and to protect against neurodegeneration.

186 -cell intracellular antigen 1 (TIA1) in vivo protects against neurodegeneration and prolongs survival

187 Inhibition of BACE1 activity protected against neuronal damage.

188 ow that Ad prime, Env protein boost vaccines protect against neutralization-resistant SIVsmE660 varia

189 ave shown that DNA prime, Ad5 boost vaccines protect against neutralization-sensitive but not neutral

190 reus to detoxify reactive oxygen species and protect against neutrophil killing, enhancing fitness wi

191 Furthermore, in vivo administration of B022 protected against not only NIK but also CCl4-induced liv

192 xercise-trained Atg7(h&mKO) mice were better protected against obesity and insulin resistance with in

193 full amplitude of the Ca(2+) transients and protected against OSI.

194 Duchenne muscular dystrophy-Hippo deficiency protected against overload-induced heart failure.

195 Antioxidants may protect against oxidative stress, which is associated wi

196 osphodiesterase expression (72.5 +/- 22.4%), protected against oxidative stress (94.7 +/- 6.2%) and n

197 vascularization development but selectively protected against oxygen-induced retinopathy (OIR) in mi

198 Caffeine preferentially protects against oxygen-induced retinopathy.

199 In this manner, HMOs help protect against pathogen colonization and reduce the ris

200 the cell wall structure and growth, and may protect against pathogen invasion.

201 Biofilm also protects against pathogenic infection and prolongs lifes

202 Host immune and physical barriers protect against pathogens but also impede the establishm

203 xpression, while suppression of this pathway protected against pathological hypertrophy both in vitro

204 BRF110 also protects against PD-related genetic mutations in patient

205 ein containing a CARD complex), or caspase-1 protected against PDA and was associated with immunogeni

206 of paranoid and threatening appraisals might protect against persistent psychotic experiences becomin

207 bone marrow prevents TGF-beta activation and protects against PH development.

208 ubtilis has rendered the engineered bacteria protected against phages from all three major families o

209 Here, we show that histone deacetylase Sirt6 protects against podocyte injury through epigenetic regu

210 t with enhanced adaptive mechanisms that may protect against postsurgical infection.

211 functions including aiding pathogenicity and protecting against predators.

212 Importantly, the mice that were protected against primary viral infection as a result of

213 KIBRA knockdown podocytes were also protected against protamine-induced injury.

214 atin 1 and myeloblastin, the former of which protects against protease activity of allergens and the

215 between molecular and cellular factors that protect against protein aggregation and those that promo

216 r adolescent trajectory and predispose to or protect against psychopathology.

217 Notably, MCP-1(-/-) mice were protected against PTH-induced cortical and trabecular bo

218 ; 95% CI, 0.72-0.96; P = 0.01) independently protected against PTT.

219 The increased TGF-beta signaling may protect against rapid retinopathy progression and should

220 dy to hepatitis B surface antigen (anti-HBs) protects against reactivation in patients with resolved

221 after a primary NPHV infection, horses were protected against rechallenge with the homologous as wel

222 ng infection and anti-HEV antibodies seem to protect against reinfection, its pathogenesis is not wel

223 that depletion of gut microbiota profoundly protects against renal I/R injury by reducing maturation

224 reviously showed that dehydroepiandrosterone protects against renal ischemia-reperfusion injury in ma

225 , we identify members of the microbiota that protect against respiratory infection by the major human

226 ate the host signaling axis they activate to protect against respiratory infection.

227 Higher levels of HDL cholesterol appear to protect against RHOA after 11 years of follow-up.

228 tosis and necroptosis and are also partially protected against RIPK1-independent apoptosis.

229 eatment for apnea suggests that caffeine may protect against ROP.

230 Here, we describe how F-specific antibodies protect against RSV and why specifically targeting prefu

231 They also protected against RSV infection in the mouse lung.

232 vector to develop a bivalent oral vaccine to protect against S. sonnei shigellosis and typhoid fever.

233 the clinical effectiveness of Ty21a-AR-Ss in protecting against S. sonnei shigellosis and typhoid fev

234 This response was sufficient to protect against Salmonella tissue invasion and involved

235 and produce specific immunity proteins that protect against self-intoxication.

236 ted with IL-10-deficient B-1a cells were not protected against sepsis.

237 ecombinant protein-based vaccine licensed to protect against serogroup B meningococcal disease.

238 colonization induce T reg cell expansion to protect against severe bronchiolitis and subsequent asth

239 Hemoglobin variants C and S protect against severe malaria but their influence on pa

240 Elevated, nontoxic doses of manganese (Mn) protect against Shiga toxin-1-induced cell death via dow

241 range of HIV-1 primary isolates in vitro and protects against simian-human immunodeficiency virus (SH

242 We hypothesize that tomato consumption would protect against skin cancer.

243 NER protects against skin cancer.

244 holinergic synaptic transmission effectively protects against spatial pattern separation impairments

245 e of skin shows that SNP309G allele actually protects against squamous cell carcinoma susceptibility.

246 coccus aureus and Streptococcus pyogenes and protected against staphylococcal alpha-toxin-induced ker

247 genotype does not offer expanded immunity to protect against subsequent infections with a different H

248 ly mediated species interactions to drive or protect against sudden ecosystem shifts.

249 Our findings suggest that female sex protects against systemic inflammation-induced endotheli

250 NOX-deficient NOD mice (NOD.Ncf1(m1J) ) were protected against T1D due, in part, to impaired proinfla

251 ed male mice challenged with Zika virus were protected against testis infection, injury, and oligospe

252 r pigment optical density (MPOD) and thereby protect against the development of age-related macular d

253 sure to a farm environment has been shown to protect against the development of inflammatory diseases

254 (Shantha Biotechnics, Hydrabad, India), can protect against the disease for up to 5 years.

255 CAR T cell therapy in solid tumors and help protect against the emergence of escape variants.

256 remature depolarizations that normally helps protect against the formation of ectopic beats.

257 It has been shown that gammadelta T cells protect against the formation of squamous cell carcinoma

258 cy in key cell types but also the ability to protect against the genetically diverse field strains.IM

259 mutants, we identify DNA repair factors that protect against the genotoxicity of ICLs generated by tr

260 There is mounting evidence that microglia protect against the incidence of AD, as impaired microgl

261 ggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscl

262 t month 12, suggesting that this genus might protect against the later development of AD.

263 following challenge and thus appeared to be protected against the acquisition of DENV2 following hig

264 hermore, increased hepatic Tm6sf2 expression protected against the development of atherosclerosis in

265 f C16-ceramide, showed that CerS6-deficiency protected against the development of colitis.

266 iples we show that these states are symmetry-protected against the information loss and thus realize

267 ry explains why metazoan species are largely protected against the negative fitness effects of cancer

268 nowledge, the role of nutrition label use in protecting against the development of chronic diseases w

269 Further, over-expression of securin or Mps1 protects against the age-related increase in inter-siste

270 In conclusion, global loss of Ces1/Ces1g protects against the development of atherosclerosis by i

271 e (HBB2), a dual activator of NRF2 and HSF1, protects against the development of UV irradiation-media

272 nvolvement, and there is no vaccination that protects against the disease.

273 ally designed experimental ASFV vaccine that protects against the highly virulent ASFV Georgia 2007 i

274 ineurin's activity toward those proteins and protects against the toxic hallmarks of alpha-syn pathol

275 ol, a phosphodiesterase III inhibitor, could protect against these changes.

276 To protect against these insults and maintain genome integr

277 In addition to protecting against those molecular effects of irradiatio

278 Reduction of YAP1 in cancer cells in vivo protects against thrombocytosis-induced increase in meta

279 cterial AB toxins that have the potential to protect against toxin-induced pathology without harming

280 tained p16(INK4a) expression is necessary to protect against tumorigenesis.

281 Inhibition of miR-204 protects against tunicamycin-induced vascular/endothelia

282 e innate and adaptive immune mechanisms that protect against ubiquitous fungal exposures.

283 et protein, heme oxygenase-1 in the skin and protected against UVB-induced oxidative stress, inflamma

284 re, an HPV16-targeted version of the DNA can protect against vaginal challenge with HPV16, suggesting

285 , and the adiponectin-T-cadherin association protected against vascular injury.

286 e cytolytic effector molecule perforin fully protected against vascular permeability and edema.

287 r-expressing rabbit calpastatin (CalpTG) are protected against vascular remodelling and angiotensin I

288 The alphaAnalogue protected against vascular, renal, and cardiac dysfuncti

289 variant and triggered by ligand functions to protect against viral challenge, which probably accounts

290 ity to elicit a broad anti-IAV response that protects against viral escape and T-cell clonal loss.

291 HIKV elicited rapid and robust immunity that protected against viremia and telemetrically monitored f

292 eins encode a prokaryotic immune system that protects against viruses and plasmids.

293 importance of N- vs O-linked sialic acid in protecting against VWF clearance and (2) whether additio

294 es to both acute and chronic stress and were protected against weight loss associated with chronic st

295 t and availability of preventive vaccines to protect against Zika virus disease.

296 dies suggest that DENV-immune serum does not protect against ZIKV infection.

297 hese results demonstrate that CD8(+) T cells protect against ZIKV infection.

298 This variant protected against ZIKV and diminished production of anti

299 ibody titers ( approximately 1/100,000) that protected against ZIKV infection and conferred sterilizi

300 in GAS antioxidant defenses and suggested to protect against zinc toxicity.