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1 lockade of dectin 1 downstream signaling was protective.
2 sk, while emotional undereating (EUE) may be protective.
3 amage, and exogenous application of hBD2 was protective.
4 accine that elicits such antibodies would be protective.
5 cutaneous white adipose tissue (WAT) appears protective.
6 ous T cell-dependent humoral response can be protective.
7 disease (AD), ApoE3 is neutral, and ApoE2 is protective.
9 nfected hepatoma cells.IMPORTANCE Due to the protective ability of HCV-specific T cells and the hepat
10 te antigens, accelerating the development of protective acquired immunity, which would take many year
11 hosts, one can expect that the efficiency of protective action of CRISPR-Cas systems against differen
12 idence for the role of RvTs in mediating the protective actions of atorvastatin and pravastatin in re
13 ting enzyme in the RvT pathway, reversed the protective actions of these statins on both joint and sy
15 r plants in the nightshade family synthesize protective acylated sugars in the tip cells of glandular
18 t studies have identified SseB as a modestly protective Ag in susceptible C57BL/6 mice, but the mecha
19 pastoris We found that recombinant I62-CFH (protective against age-related macular degeneration) and
21 e in a range of cellular assays, were poorly protective against HIV-1 infection of mucosal tissues.
24 nduced antibodies to HIV that were partially protective against infection, as well as antibodies to H
26 2 signaling reduces neuroinflammation and is protective against neurodegeneration in the setting of p
27 tration improves endothelial function and is protective against oscillatory shear stress-induced endo
28 ologic evidence that dietary fiber intake is protective against overweight and obesity; however, resu
29 accine that has been reported to be safe and protective against P falciparum controlled human malaria
30 of warning received showed evidence of being protective against symptoms of the three mental illnesse
32 in total energy intake from LC n-3 PUFAs in protective-allele (C-allele) carriers, whereas the corre
34 ene fatty acids are formed in vivo and exert protective and anti-inflammatory effects via reversible
36 2 and varepsilon4 alleles of APOE harbouring protective and risk increasing effects, respectively, in
37 age-specific and long-lived pre-erythrocytic protective anti-malarial immunity, mediated primarily by
38 accine induced higher-magnitude, potentially protective anti-V1V2 IgG responses than in adult vaccine
39 haracterization of the epitope recognized by protective antibodies may facilitate design of peptidomi
42 apies is hampered by the gap in knowledge of protective antibody epitopes on the HAstV capsid surface
43 une responses have the potential to maintain protective antibody levels for years due to the immunogl
44 PC that are recognized by these potentially protective antibody responses are only poorly defined.
46 hem, the Plasmodium falciparum Cysteine-Rich Protective Antigen (PfCyRPA) is a crucial component of a
47 xpresses a variety of structurally conserved protective antigens that include cell surface polysaccha
52 ser risk of acute pancreatitis, and that the protective association was significant among cases of bo
56 array of mimetic relationships that provide protective (Batesian mimicry) and predatory (aggressive
58 ut sun safety behavior, which would make sun protective behavior more likely, could be promoted and s
59 itivity from infections may discourage these protective behaviors, even at temperatures below critica
60 to environmental decoherence because of the protective beta-barrel structure that encapsulates the f
62 s that recognize influenza A virus HA can be protective, but the mechanism is not completely understo
64 in G-protein signaling or simply serve as a protective cap for the activating "Stachel" sequence.
65 ng in vitro cold hypoxic injury improved the protective capacity of H2 S >1000-fold compared to simil
66 e overload, an increase in leptin levels has protective cardiac effects with respect to rescuing the
67 tuberculosis (TB) is that the attributes of protective CD4(+) T cell responses are still elusive for
68 were more likely to report never/rare use of protective clothing (adjusted prevalence ratio [aPR], 1.
69 This commentary uses the dynamic of identity-protective cognition to pose a friendly challenge to Jus
70 r antecedent hypoglycemia causes blunting of protective counterregulatory responses, known as hypogly
71 study, we report the development of a highly protective CSP-based P. vivax vaccine, a virus-like part
75 was characterized by increased production of protective cytokines IFN-gamma, TNF-alpha, and IL-12, as
76 esponses, we found persistent degradation of protective ECM structures called perineuronal nets (PNNs
77 to steroid treatment shows a trend toward a protective effect (odds ratio, 0.16; 95% CI, 0.0-1.3; P
78 diet-induced liver injury and abolished the protective effect against cholesterol lipotoxicity in So
84 is study adds to the limited evidence of the protective effect of adherence to a Mediterranean dietar
85 ar endothelial growth factor strengthens the protective effect of amniotic fluid stem cells in a rena
86 y active Nlrp3(A350V) mutation abolished the protective effect of aPC, demonstrating that Nlrp3 suppr
87 In this report, we investigated the retina-protective effect of chrysophanol, an active component o
91 atic review and meta-analysis quantified the protective effect of facemasks and respirators against r
94 ovide a mechanistic basis for the dominantly protective effect of HLA in autoimmune disease, whereby
95 observational studies provided evidence of a protective effect of masks (OR = 0.13; 95% CI: 0.03-0.62
96 terial from an untreated mouse abolished the protective effect of microbiota depletion upon renal I/R
98 quired to confirm and further characterize a protective effect of physical activity on the onset and/
101 pathway of CYP142A1, while CIU revealed the protective effect of the heme group on the structure of
103 as 2 mo, suggesting that GRP78 could exert a protective effect on acinar cells under stress, as durin
108 APOE epsilon2/epsilon3 genotype conferred a protective effect on women (OR, 0.51; 95% CI, 0.43-0.61)
114 parum malaria, but the precise nature of the protective effecthas proved difficult to define as G6PD
116 like macrophages in fibrotic liver exert the protective effects against lethal insults through confer
117 tivity in APP mice; and that SS31 may confer protective effects against mitochondrial and synaptic to
119 ies show that PDE5 inhibitors (PDE5is) exert protective effects in DN improving perivascular inflamma
122 in-3 protein, plays an important role in the protective effects of calpain inhibition for the treatme
123 ated from CpG-treated mice recapitulated the protective effects of CpG when administered before aller
124 ese data provide a mechanistic basis for the protective effects of the antibody in vitro and in vivo,
126 ton, a 5-LOX inhibitor with VPC reversed the protective effects of VPC against neuroinflammation.
130 hich is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus s
131 V glycoproteins for their immunogenicity and protective efficacy in cotton rats and African green mon
134 ing whether there may, or may not, have been protective efficacy in the RV144 vaccine trial have impo
135 ompared in vitro and in vivo the potency and protective efficacy of 5C4 and the murine precursor of p
137 current study, we examined the long-lasting protective efficacy of chimeric VLPs (cVLPs) containing
138 To test this assumption, changes in the protective efficacy of the immune response to B. burgdor
140 ruses influenced HAI-specific antibodies and protective efficacy using a broadly protective vaccine c
145 ograms macrophages and tubules to generate a protective environment, in which tissue health is preser
148 moderate-to-high myopia, and none were using protective eyewear when they sustained the eye trauma.
149 analysis showed that LMWH was an independent protective factor against mortality and thromboembolic c
152 of suicide in OCD and identify the risk and protective factors associated with suicidal behavior in
153 ially captures environmental risk factors or protective factors has direct implications for risk pred
154 exposure to tobacco smoke, and prematurity; protective factors include breastfeeding, pacifier use,
158 instead have a "settler" phenotype, forming protective flocs and tending to remain in their current
159 lammatory (M1) macrophage activation and was protective for multiple CNS cell types, indicating its p
161 ty of the cells to perform another important protective function, namely absorption of stray light.
165 ocols have been developed to remove benzyl O-protective groups from oxyarene N-heterocycles at positi
166 led to a less-diverse microbiome and loss of protective gut commensal strains (of the family Lachnosp
169 ncated or produced in CHO cells.IMPORTANCE A protective HIV-1 vaccine will likely include a recombina
170 ctor cells in vitro Among persons expressing protective HLA class I alleles, carriage of Nef codon 9
171 nfers a markedly increased disease risk, the protective HLA-DR1 allele is dominantly protective in tr
174 00% (n=48/48) of vaccine recipients achieved protective hSBA titres equal to or greater than the lowe
177 Tools that enable the rapid evaluation of protective immune responses are essential to vaccine dev
178 n-specific immunotherapy is the induction of protective immune responses in the absence of anaphylact
179 ines have been shown to provide better cross-protective immune responses than inactivated vaccines by
180 erior humoral immune responses and conferred protective immunity against a lethal challenge dose of h
181 nstrate that CD8(+) T cells are required for protective immunity against a naturally occurring murine
182 promising candidates to examine induction of protective immunity against heterologous pathogens.
183 CD4 TEMRA cells have been implicated in protective immunity against pathogens such as dengue vir
184 cination with the batA mutant strain elicits protective immunity against subsequent infection with wi
185 mechanism has likely evolved to both sustain protective immunity and avoid autoantibody production.
187 -modified mRNA-LNP elicits rapid and durable protective immunity and therefore represents a new and p
188 ogens, we validate that the prime targets of protective immunity are conformational epitopes at the d
189 ll responses.IgE is an important mediator of protective immunity as well as allergic reaction, but ho
191 ion by Toxoplasma gondii triggers a lifelong protective immunity due to the persistence of parasitic
192 studies typically examined the biomarkers of protective immunity however the biomarkers of attenuatio
193 ported to be associated with vaccine-induced protective immunity in challenge studies involving nonhu
194 ng the high-avidity epitope SSIEFARL induced protective immunity irrespective of gene expression cont
195 juvant properties that improve SseB-mediated protective immunity provided by circulating memory.
197 1 and Th17 cells have an established role in protective immunity to Bordetella pertussis, but this ev
198 her delineate mechanisms whereby HIV impairs protective immunity to M. tuberculosis, we evaluated the
199 l tumor-associated stroma (TAS) to configure protective immunity within the tumor microenvironment.
200 ovirus is an avirulent pathogen that elicits protective immunity, but we discovered that it can nonet
209 dermal model of infection yet still elicited protective immunity.IMPORTANCE The vaccinia virus (VACV)
213 tment with NKH-477, a compound discovered as protective in our previous studies on Krabbe disease, wh
214 infection in which antimicrobial immunity is protective in the vast majority of infected individuals
221 ored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability
222 ed C,H insertion reactions and consists of a protective layer, which shields the contacting solution
223 modest defects in the assembly of the spore protective layers that are exacerbated in the presence o
224 ring repeated malaria exposures would induce protective long-lived sterile immunity targeting pre-ery
228 idence that the innate immune system employs protective mechanisms aimed at mitigating the risk of po
230 hat must rely mainly or exclusively on other protective mechanisms, although non-human primate (NHP)
231 Defining the role of beneficial allergy-protective members of the microbiota in the regulation o
238 ve sensory input, the neural signals trigger protective (nocifensive) behaviors, and the sensory stim
239 sess whether neutrophils exert predominantly protective or deleterious effects on loss of B cell self
240 whether the high level of LCN2 in the CNS is protective or deleterious, we challenged Lcn2(-/-) mice
241 matory and infectious diseases, and may have protective or pathogenic effects, depending on the tissu
243 ion of ceramic result in much slower loss of protective oxide layers formed during ablation than othe
246 hin during AirR overproduction abolished the protective phenotype of increased staphyloxanthin produc
247 central adiposity, rather than reflecting a protective physiologic effect of higher body-fat content
248 Bacteria have the natural ability to install protective postsynthetic modifications onto its bacteria
252 ants and compare the prevalence of 3 malaria-protective red blood cell polymorphisms in BWF cases vs
253 r human cell models, TRAP1 overexpression is protective, rescuing HTRA2 and PINK1-associated mitochon
255 hagocytic activity and representative of the protective response against type III GBS polysaccharide.
258 indicate that endothelial EPAS1 has a global protective role during glomerular hypertensive injuries
259 model of genital infection, we demonstrate a protective role for both Chlamydia-specific immunoglobul
260 nducible NO synthase, suggesting a potential protective role for these IFN-gamma-producing cells.
261 ed acute GVHD, consistent with an additional protective role for this cytokine independent of effects
262 sion, our data indicate that IL-22BP plays a protective role in acute liver damage, via controlling I
267 st that epithelial expression of NUPR1 has a protective role in response to injury after renal transp
268 changes in the gut microbiota that played a protective role in the development of cardiovascular dis
272 miR-218-5p mimic or inhibitor demonstrated a protective role of miR-218-5p in cigarette smoke-induced
273 thus elucidates a pathogenic, as opposed to protective, role for IL-17A during Gram-positive bacteri
277 somal dynamics, promotes normal induction of protective stress genes, and rescues stress sensitivity
282 ith sensitization to food fails to stimulate protective tolerogenic pathways, leading to the developm
284 ction against the vaccine-specific and cross-protective types in unvaccinated individuals born in 199
288 nt combination contributes to a more broadly protective vaccine while demonstrating an attractive saf
289 e responses, vDeltaK1L vaccination induced a protective VACV-specific CD8(+) T cell response and prot
291 tial neuromuscular blockade facilitates lung-protective ventilation during partial ventilatory suppor
292 l on clinical outcomes and adherence to lung-protective ventilation in patients with acute respirator
296 f Science, Bardina et al. (2017) explore the protective versus pathogenic roles of DENV-immune antibo
297 laining why DLK inhibition is only partially protective, we identify leucine zipper kinase (LZK) as c
300 ed that melanocortin obesity syndrome may be protective with respect to obesity-associated cardiovasc
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