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1 CBU0077 MceA (mitochondrial Coxiellaeffector protein A).
2 substrate is now termed ElpA (ER-localizing protein A).
3 alently modified by Protein-A (Glass/ZnO-NRs/Protein-A).
4 odel protein, the B domain of staphylococcal protein A.
5 g with elongation factor G and BPI-inducible protein A.
6 lpha toxin and the increased accumulation of protein A.
7 exposure to surfactant lipids and surfactant protein A.
8 ntaining multifunctional FHV RNA replication protein A.
10 purification, we developed a high throughput protein A affinity capture step coupled to inline mass s
11 On an industrial scale, replacing fouled Protein A affinity chromatography resin accounts for a l
12 led to form BsAbs that were purified through protein A affinity chromatography to demonstrate industr
14 demonstrate that A. marginale outer membrane protein A (AmOmpA; AM854) contributes to the invasion of
15 ase rapidly hydrolyzes Staphylococcus aureus protein A, an important S. aureus virulence factor invol
17 rmed within the colloidal suspensions (i.e., Protein A and antibody binding) for tailored and specifi
21 ic Thermus thermophilus multidrug resistance proteins A and B (TmrAB), which not only shares structur
22 report that the ER-resident VAMP-associated proteins A and B (VAPA and VAPB) interact with the perox
23 ins, the fibrinogen- and fibronectin-binding proteins A and B, were found to bind plasminogen, and on
24 variants of the diverse pneumococcal surface proteins A and C (PspA and PspC) and zinc metalloproteas
25 says that combined monoclonal (outer surface protein A) and polyclonal antibodies were performed on a
26 nd nucleotide excision repair is replication protein A, and we find that its accumulation on UVB-dama
27 od specificity for XPA over RPA (replication protein A), another DNA-binding protein that participate
29 energy for the interaction of Glass/ZnO-NRs/Protein-A/Anti-OTA with OTA were calculated, analyzed an
31 sicle-associated membrane protein-associated proteins A/B) and ACBD5 (acyl Co-A binding protein 5).
32 this general model to study assembly of FtsZ protein, a basic element in the division process of prok
34 quantitative detection of Galectin-1 (Gal-1) protein, a biomarker for the onset of multiple oncologic
38 rameshifting (-1 PRF) to synthesize the NS1' protein, a C terminally extended version of its non-stru
43 ys identified features on the surface of the protein-a cationic patch and a unique hydrophobic loop-t
45 s (CME) and independently of choline binding protein A (CbpA)/laminin receptor, CbpA/polymeric immuno
48 tes are epigenetically defined by centromere protein A (CENP-A), a centromere-specific histone H3 var
49 ovided by the histone H3 variant, centromere protein A (CENP-A), but the molecular mechanisms that un
51 mere-specific H3 histone variant, centromere protein A (CENP-A), shares about 50% amino acid sequence
54 MOylation' alters the behavior of the target protein, a change that is utilized to regulate diverse c
55 -based assay by stably expressing 2 reporter proteins (a chimeric coagulation factor and MGP) in HEK2
56 observed a substantially reduced replication protein A- chromatin immunoprecipitation signal at origi
57 t concentration for assessing performance of protein A chromatography resin during purification of mo
58 est increases in concentration of C-reactive protein, a circulating marker of inflammation, have been
59 evealed that the highly surface-expressed M1 protein, a classical GAS virulence factor, was required
61 n IgG1 monoclonal antibody (mAb) purified by Protein A column elution, cation exchange chromatography
63 rotein signaling homology domain-interacting protein), a component of the LUBAC (linear ubiquitin cha
64 tes hypoxia responses by demethylating RACK1 protein, a component of hypoxia-inducible factor (HIF) u
65 id surfactants, including phospholipids, and proteins, a composition similar to pulmonary surfactants
67 ounted a CD4(+) T-cell response to the H5 HA protein, a correlation not observed for NP-specific resp
68 ophosphate (cAMP) responsive-element-binding protein, a crucial mediator in long-term memory formatio
69 d between PP1c and PPP1R7, cold-shock domain protein A (CSDA), and phosphodiesterase type-5A (PDE5A)
71 outputs included an immunogenic cell-surface protein, a cytokine, a chemokine, and a checkpoint inhib
72 tingly, FACIN is a nonclassical cell surface protein, a cytosolic enzyme acetylornithine transaminase
74 adhesion was mediated by the decorin-binding protein A (DbpA) and DbpB surface molecules of B. garini
76 erstand PN activation/detoxification by heme proteins, a definitive assignment of I435 is needed.
77 olves the histone variant CENP-A (centromere protein A), deposited by its chaperone, HJURP (Holliday
80 to identify potential inhibitors of the PyrD protein, a dihydroorotate dehydrogenase (DHODase) involv
82 atase domain protein, a putative RNA-binding protein, a DNA methylase, an ATPase-domain protein, and
84 7, which encodes a homolog of disulfide bond protein A (dsbA) of Escherichia coli, is required for l-
85 Results indicated that an arginine based Protein A elution buffer minimized the levels of HCPs id
86 re examined for mAbs purified with different Protein A elution buffers to ensure that the selected bu
87 processing parameters such as harvest time, Protein A elution buffers, and subsequent DSP steps can
88 contaminating parental mAbs by differential protein A elution starting from either a) purified paren
89 quently, surfactant lipids and/or surfactant protein A enhance CD36 transcript and protein levels.
90 et-derived growth factor) and two monovalent proteins (a Fab fragment and the transcription factor TB
91 mportantly, expression of adipose FA binding protein (A-FABP) in macrophages facilitated metabolism o
92 biological function of serine-arginine (SR) proteins, a family of essential regulators of mRNA splic
95 novel interactions with domain 2 of the CTC protein, a feature typical to various Gram-positive bact
97 o contain large numbers of often-polymorphic proteins, a finding at odds with many current efforts in
98 e SaeRS-modulated factor fibronectin-binding protein A (FnBPA) also contributed to the fermentative b
99 nchored proteins such as fibronectin-binding protein A (FnBPA) that bind to host ligands (e.g. fibron
100 AB significantly altered the abundance of 76 proteins (a fold change >1.4, or <0.6, p-value <0.05) an
101 xameric coiled-coil bundle and an Fc-binding Protein A fragment, we generated the Hex nanocarrier tha
102 ble light-induced protein dissociation using protein A fragments that bind to the LOV domain only in
103 that reflects IgG binding sites conferred by Protein A/G (pAG) conjugated with the fluorogen malachit
107 ploys neodymium magnetic sticks that capture protein A/G-coated paramagnetic beads bound to antibody-
108 us sequence typing (MLST) and staphylococcal protein A gene (spa) typing results as well as SmaI macr
109 Panton-Valentine leukocidin (PVL) genes, the protein A gene (spa), and arcA and opp3, proxy markers f
110 ty, triglycerides, liver enzymes, C-reactive protein, a genetic score representing insulin resistance
112 orces underlying emergence of beta-propeller proteins, a globular and symmetric fold group with diver
113 jor histocompatibility complex (MHC) class I proteins, a hallmark of early beta-cell inflammation in
115 stinct enzymatic activities of Sir2 and Top1 proteins, a histone deacetylase and a DNA topoisomerase,
117 increased expression of myxovirus resistance protein A in the skin and induction of interferon-stimul
118 and Polycomb Repressive Complex 2-associated protein; a.k.a. C17orf96, esPRC2p48, and E130012A19Rik)
119 rast, CYLD (cylindromatosis tumor-suppressor protein), a K63-specific deubiquitinase enriched in post
122 miR-BART16 directly targets CREB-binding protein, a key transcriptional coactivator in IFN signal
123 o leads to increased degradation of the Mfn2 protein, a key ubiquitylation target of Parkin on mitoch
124 module, hipBA, encodes HipA (high persister protein A) kinase, which inhibits glutamyl tRNA syntheta
125 PKCalpha interaction with the PKC-targeting protein A-kinase anchoring protein (AKAP) 79 and interfe
129 hat EGCG can induce the aggregation of HMGB1 protein, a late mediator of inflammation, which subseque
130 t KRAS have focused on inhibiting the mutant protein; a less explored approach involves targeting KRA
131 t application demonstrates the monitoring of protein A ligand density and foulant concentration for a
133 umoniae lacking the CBP pneumococcal surface protein A lost its ability to inhibit the IgG anti-cOVA
134 cted to APP (encoding amyloid beta precursor protein), a major player in Alzheimer's disease that is
135 tion protein, and small proline-rich (Sprr2) protein, a major component of cornified envelopes in ker
136 r-interacting amino acid residues in the VP2 protein, a major determinant of viral receptor binding a
138 the de-repression of thioredoxin-interacting protein, a major redox control molecule, and consequent
139 With <2% of the human genome coding for proteins, a major challenge is to interpret the function
140 yrosine- and serine/threonine-phosphorylated proteins, a marked increase in cellular Tropomyosin-3, p
141 ut remained, after adjustment for C-reactive protein, a marker of low-grade inflammation (mean differ
142 ncreased bronchoalveolar lavage fluid (BALF) protein, a marker of lung permeability, in all genotypes
143 n pumps perturb the membrane surrounding the protein, a mechanism is suggested whereby dipole potenti
144 protective fibrin shields via coagulases and protein A-mediated B cell superantigen activity, are dis
145 chanism wherein membrane binding of a second protein (a membrane interacting chaperone, Hsp27, in thi
147 ation between cytoskeletal and actin-binding proteins, a mesenchymal or hybrid EMT phenotype and inva
149 tors-the heteromeric macrophage growth locus protein A (MglA)-stringent starvation protein A (SspA) c
151 The IFN-induced human myxovirus resistance protein A (MxA) exhibits a broad antiviral activity agai
153 global conformational polymorphism of capsid proteins, a network formed by extended N arms, mortise-a
154 utualistic relationship of nucleic acids and proteins, a network known as life's central dogma, is no
155 na) MITOCHONDRIAL TRANSLATION FACTOR1 (MTL1) protein, a new member of the Pentatricopeptide Repeat fa
158 median fold changes were SAA (serum amyloid protein A), NPS-PLA2 (secreted phospholipase A2), and CA
160 n of XPA with DNA is a core function of this protein; a number of mutations in the DNA-binding domain
161 nding protein (MBP), N-utilisation substance protein A (NusA), human protein disulphide isomerase (PD
164 testing, sexual history, and outer membrane protein A (OmpA) genotyping of C. trachomatis strains.
166 l antibodies (MAbs) targeting outer membrane protein A (OmpA) of A. baumannii Five anti-OmpA MAbs wer
167 ous studies demonstrated that outer membrane protein A (OmpA) of E. coli K1 interacts with endothelia
169 transport protein (DppA), and outer membrane protein A (OmpA) were identified as proteolytic substrat
171 trations of antibodies against outer surface protein A (OspA) were shown to correlate with protection
173 talloproteinase, pregnancy-associated plasma protein-A (PAPP-A), which modulates insulin-like growth
175 phoblast-derived pregnancy-associated plasma protein A (PAPPA) is specifically elevated in pregnant w
178 rticular mRNAs to produce plasticity-related protein; a phenomenon exhibited during mGluR-mediated LT
179 Ltn1 results in the aggregation of aberrant proteins, a phenomenon that requires CAT-tail addition t
180 ass III photolyase termed photolyase-related protein A (PhrA) of Agrobacterium tumefaciens at 1.67-A
181 ning, and discovery of (novel) PKA anchoring proteins, a plethora of methodologies is available, incl
184 an to any of the other isoforms, making this protein a potential candidate for diagnosis and immunoth
185 I-QTOF analysis was employed to identify the proteins, a prerequisite to translate the mass of quanti
186 this ubiquitous family of membrane-spanning proteins a prime target for toxins found in animal venom
187 h functions to clear endogenous mannosylated proteins, a principle used to endow insulin analogs with
188 viruses often inhibit the production of host proteins, a process that is referred to as host shutoff.
190 immune response to coimmunized heterologous proteins, a property not observed with several other int
191 nstrated using the Hepatitis B virus X (HBx) protein, a protein of unknown function, as a test case.
192 The vaccinia virus (VACV) M1 ankyrin (ANK) protein, a protein with no previously ascribed function,
194 d by anti-OTA and BSA in this way a anti-OTA/Protein-A/PSi structure sensitive towards OTA was design
196 free energy for the interaction of anti-OTA/Protein-A/PSi with OTA were calculated and analyzed usin
199 for rapid detection of pneumococcal surface protein A (PspA) peptide and SP lysate from synthetic an
201 oteins (PhtD and PhtE), pneumococcal surface protein A (PspA), plasminogen and fibronectin binding pr
202 orkflow includes an automated, 96-well plate protein A purification step to isolate antibody product
203 s present in monoclonal antibodies following Protein A purification.1 To improve the HCP detection li
204 applied to determine HCP repertoires in the Protein A purified monoclonal antibody (mAb) samples as
205 ike protease, an alkaline phosphatase domain protein, a putative RNA-binding protein, a DNA methylase
207 ar response is initiated through a signaling protein (a receptor), which interacts with the "signal",
208 dular design consisting of the fusion of two proteins: a recognition protein that binds a triggering
210 ive construction means that, unlike globular proteins, a repeat protein's equilibrium folding and thu
211 ation (Tat) pathway, which transports folded proteins, a requirement for cofactor assembly before tra
213 o found that host cell proteins bound to the Protein A resin even more strongly than mAbs and that ty
214 ce (CIP) procedures were developed to extend Protein A resin lifespan, but chromatograms cannot relia
215 ng for Neural retina-specific leucine zipper protein, a rod fate determinant during photoreceptor dev
216 DNA, which are rapidly bound by replication protein A (RPA) and other single-stranded DNA binding pr
217 gle-stranded DNA binding protein replication protein A (RPA) as a regulator of the deposition of newl
219 HCV NS5A(S25-C447) and cellular replication protein A (RPA) functionally cooperate as a processivity
223 gle-stranded DNA binding protein replication protein A (RPA) on damaged chromatin and severely abroga
224 gle-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERCC1 endonucle
227 s of the repair complex, such as replication protein A (RPA), is controlled in part by a dynamic acet
229 sh2-Msh3), exonuclease 1 (Exo1), replication protein A (RPA), RFC, PCNA, and DNA polymerase delta.
230 interacts with and ubiquitylates replication protein A (RPA), show profound defects in ICL repair.
232 Cell Nuclear Antigen (PCNA) and Replication Protein A (RPA), which are critical for DNA replication
234 interactions of human RAD52 with replication protein A (RPA)-coated ssDNA, and we monitored the fate
242 motes DNA end joining, regulates replication protein A (RPA2) phosphorylation and ubiquitination at d
243 rotein [CRP], haptoglobin, and serum amyloid protein A [SAA]), inflammatory markers (matrix metallopr
246 a binding motif for the quaking RNA binding protein, a sequence we show can significantly regulate m
247 To better understand the activity of this protein a series of mutants, targeted to the NADH co-fac
248 eta signaling pathway and alpha1-antitrypsin protein (a serine protease inhibitor) expression and dow
251 peptide A, derived from lactoferrin-binding protein A, showed superior activity in immunogenicity an
252 largest number of genes mapped to ribosomal proteins, a signature hitherto not associated with linez
255 uses it to complement its own nuclear export proteins (a site not targeted by current therapy), makin
263 ptibility, biofilm formation, Staphylococcal protein A (spa) typing, SCCmec typing, and PCR-based ass
265 ntation to CD4(+) T cells and staphylococcal protein A (SpA), a cell wall-anchored surface molecule t
266 esponse through expression of staphylococcus protein A (SpA), a surface protein that drives polyclona
267 etic beads, specific antibodies against IL-8 protein, a specific hairpin DNA sequence for IL-8 mRNA a
268 locus protein A (MglA)-stringent starvation protein A (SspA) complex and the DNA-binding protein pat
269 showed that the E. coli stringent starvation protein A (SspA) shares sequence and structural homology
270 screened against three human galectin (hGal) proteins (a stable mutant of hGal1 (hGal-1), a C-termina
271 gosaccharides (HMOs) for four human galectin proteins, a stable mutant of hGal1 (hGal-1), a C-termina
273 e has demonstrated that polycomb group (PcG) proteins, a subset of histone-modifying enzymes known to
276 c behaviour is closer to that of Replication Protein A than to Escherichia coli SSB; a feature that m
277 metry data for chicken egg lysozyme, mutated Protein A, three wild-types of haloalkane dehalogenases,
279 echanisms ensure that the mRNA encoding Hac1 protein, a transcription factor involved in the unfolded
281 asmic polyadenylation element binding (CPEB) protein, a translational regulator that recruits mRNAs a
285 rylating and inactivating the retinoblastoma protein, a tumor suppressor that restrains G1- to S-phas
286 nce of specific antibodies against the GTF2b protein, a tumor-associate antigen (TAA) related to colo
287 CHIP (carboxyl terminus of Hsc70-interacting protein), a U-box E3 ligase, suppresses tumor progressio
288 r with other tumor biomarkers and C-reactive protein, a universal biomarker for infection and inflamm
289 ice and amongst the differentially expressed proteins a V-ATPase and a 14-3-3 protein were down-regul
290 ide context, such as with the erythropoietin protein, a V3 polypeptide derived from HIV-1 gp120, or a
293 of the proteoglycan versican and its linking protein, a vertebrate hyaluronan and proteoglycan link p
294 specifically interacts with RPA (Replication protein A) via two conserved RPA-binding domains and is
295 ional groups-carboxyl groups of Alb NPs, p19 protein, a viral protein that can bind and sequester sho
296 nant HSV-1 with a mutation in the gamma134.5 protein, a virulence factor, stimulates dendritic cell (
300 ons of unfolded and intrinsically disordered proteins: A wide range of experimental techniques sugges
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