ライフサイエンスコーパス: protein biosynthesis

1 oacyl-tRNAs (aa-tRNAs) onto the ribosome for protein biosynthesis.

2 the main target for antibiotics that inhibit protein biosynthesis.

3 at is dependent on TNF signaling and de novo protein biosynthesis.

4 ntegration at the translocon during membrane protein biosynthesis.

5 t dissociate into subunits in order to begin protein biosynthesis.

6 havior of incomplete chains generated during protein biosynthesis.

7 eins, and enzymes involved in amino acid and protein biosynthesis.

8 nce of molecular chaperones participating in protein biosynthesis.

9 metabolism and cell wall, nucleic acid, and protein biosynthesis.

10 ting can modulate mRNA function and rates of protein biosynthesis.

11 may selectively and differentially modulate protein biosynthesis.

12 l hemoglobin, far more than they require for protein biosynthesis.

13 mechanisms to ensure quality control during protein biosynthesis.

14 he other route to this essential compound in protein biosynthesis.

15 has been shown to block translocation during protein biosynthesis.

16 in the ribosome is a fundamental step during protein biosynthesis.

17 st suggests that organisms minimize costs of protein biosynthesis.

18 cyl groups mimic a chemistry found in modern protein biosynthesis.

19 ion of proteins involved in cytoskeleton and protein biosynthesis.

20 ll cycle progression and on nucleic acid and protein biosynthesis.

21 lidinones are potent inhibitors of bacterial protein biosynthesis.

22 lationship between amino-acid metabolism and protein biosynthesis.

23 ons with mRNA, tRNA and other ligands during protein biosynthesis.

24 ptidyl-tRNA hydrolysis during termination of protein biosynthesis.

25 onment during 2 h of inhibition of host cell protein biosynthesis.

26 genes proposed to be involved in iron-sulfur protein biosynthesis.

27 ty of the TFEB protein and altered lysosomal protein biosynthesis.

28 d suggest a role for ubiquitination early in protein biosynthesis.

29 receptor chimaera in the absence of de novo protein biosynthesis.

30 ource of GTP for translational elongation in protein biosynthesis.

31 al subunits, and reduced activity of plastid protein biosynthesis.

32 here they served as precursors for bacterial protein biosynthesis.

33 conserved process for secretory and membrane protein biosynthesis.

34 and the second, more potent as inhibitors of protein biosynthesis.

35 otein S6 was also modulated by inhibition of protein biosynthesis.

36 eIF3 plays a key role in protein biosynthesis.

37 so activated by reduction in the accuracy of protein biosynthesis.

38 ant life employs the same 20 amino acids for protein biosynthesis.

39 the E1 molecule and then utilize tyrosine in protein biosynthesis.

40 r a spring between these two proteins during protein biosynthesis.

41 ative activity, and amino acid transport and protein biosynthesis.

42 nsensitive to cycloheximide, an inhibitor of protein biosynthesis.

43 some of which encode proteins that modulate protein biosynthesis.

44 0 inhibition because of their high amount of protein biosynthesis.

45 ly linked to ribosomes and are implicated in protein biosynthesis.

46 ly to be important for optimizing functional protein biosynthesis.

47 olved in gametogenesis while down-regulating protein biosynthesis.

48 ment, cell invasion, antigenic variation and protein biosynthesis.

49 ti-gene operons, thus coordinating ribosomal protein biosynthesis across multiple operons.

50 that post-translational modifications during protein biosynthesis along secretory pathways play criti

51 ddition to their essential catalytic role in protein biosynthesis, aminoacyl-tRNA synthetases partici

52 by upregulation of enzymes involved in both protein biosynthesis and biosynthetic pathways, as well

53 I- and Pol II-transcribed genes required for protein biosynthesis and cell cycle progression.

54 nscriptional pattern suggestive of increased protein biosynthesis and cellular proliferation.

55 amino acids are the basic building blocks of protein biosynthesis and contribute to many other metabo

56 ng quality control processes associated with protein biosynthesis and cotranslational folding (CTF).

57 A link was recently established between protein biosynthesis and cytokine signal transduction.

58 is maintained and regulated by the rates of protein biosynthesis and degradation in living systems.

59 olved in signal transduction, transcription, protein biosynthesis and degradation, and cell motility,

60 assessed by measuring adhesive strength, and protein biosynthesis and deposition were determined by i

61 s to the up-regulation of genes essential to protein biosynthesis and energy production.

62 ks-1/S6 kinase or in ife-2/eIF4E also reduce protein biosynthesis and extend lifespan, but only rsks-

63 Protein biosynthesis and extracellular secretion are ess

64 transcription of genes involved in secretory protein biosynthesis and granule-vesicle formation.

65 Ribotoxins are potent inhibitors of protein biosynthesis and inactivate ribosomes from a var

66 ed, RRE RNA secondary structure prevents Ant protein biosynthesis and lytic development.

67 amino acid implicated in energy metabolism, protein biosynthesis and neurotransmission.

68 ycle, starch biosynthesis, lipid metabolism, protein biosynthesis and processing.

69 ncentrate iron in iron-oxy minerals for iron-protein biosynthesis and protection against oxy radical

70 Moreover, protein biosynthesis and rRNA production were decreased

71 nificant over-representation of genes in the protein biosynthesis and stress response categories.

72 o the Kozak consensus sequence for mammalian protein biosynthesis and the 3'-UTR demonstrated three c

73 thesis of aromatic amino acids essential for protein biosynthesis and the production of a wide array

74 ted functions were over-represented in loopy proteins, biosynthesis and energy metabolism were under-

75 g the kinases PIM2 and DYRK3, which regulate protein biosynthesis, and a number of genes in cilium bi

76 ases in genes regulating membrane integrity, protein biosynthesis, and apoptosis.

77 ntral metabolism, including gluconeogenesis, protein biosynthesis, and purine/pyrimidine synthesis wa

78 ated with apoptosis, mitochondrial function, protein biosynthesis, and RNA binding.

79 ve effect of CHES1, indicating that PIM2 and protein biosynthesis are important targets of the antipr

80 e proteins (SvsR) is presumed to function in protein biosynthesis, because it exhibits a high degree

81 bit bacterial growth and cell-free ribosomal protein biosynthesis but also harbors an orthogonal func

82 t affected by cycloheximide, an inhibitor of protein biosynthesis, but is affected by proteasome inhi

83 gonist exposure and stimulation of secretory protein biosynthesis by agonist.

84 he A-tRNA entrance corridor, thus inhibiting protein biosynthesis by blocking the binding site of the

85 minoacyl-tRNA synthetases play a key role in protein biosynthesis by catalyzing the specific aminoacy

86 y activates GADD34, which promotes ER client protein biosynthesis by dephosphorylating phospho-Ser 51

87 ropose that oxazolidinones inhibit bacterial protein biosynthesis by interfering with the binding of

88 transport particle, and may control storage protein biosynthesis by regulating one or more processes

89 Lysyl-tRNAs are essential for protein biosynthesis by ribosomal mRNA translation in al

90 ossibility that small molecules can regulate protein biosynthesis by selectively binding to mRNA.

91 These findings suggest that inhibition of protein biosynthesis can alter degradation of some prote

92 ation that the four fundamental reactions of protein biosynthesis can be RNA-mediated.

93 and cellular growth, indicating that reduced protein biosynthesis can confer a suppressive effect on

94 teins in the dark, suggesting that cell wall protein biosynthesis ceased during the night.

95 n of transcription (actinomycin D, 4 mum) or protein biosynthesis (cycloheximide, 70 mum).

96 ipts proved time-, dose-, nitric oxide-, and protein biosynthesis-dependent but glucose independent.

97 e the first committed step in O-glycosylated protein biosynthesis, determine sites of O-glycosylation

98 ghly significant number of genes involved in protein biosynthesis displayed an increase in transcript

99 critical transitions in progression include protein biosynthesis, E26 transformation-specific (ETS)

100 Movement, cell division, protein biosynthesis, electron transfer against an elect

101 tics to identify genes co-occurring with the protein biosynthesis enzyme SepCysS, which converts phos

102 idant defense enzymes, molecular chaperones, protein biosynthesis enzymes, and trafficking and degrad

103 th conditions of mammalian mRNAs that encode protein biosynthesis factors and contain hallmark 5'-ter

104 ic reticulum (ER) is a central organelle for protein biosynthesis, folding, and traffic.

105 for physiological disorders associated with protein biosynthesis, folding, trafficking, and membrane

106 work of molecular interactions that balances protein biosynthesis, folding, translocation, assembly/d

107 romolecular assembly that is responsible for protein biosynthesis following genetic instructions in a

108 lta strains and that the stress response and protein biosynthesis gene categories were coordinately r

109 lthough correct tRNA 3' ends are crucial for protein biosynthesis, generation of mature tRNA 3' ends

110 lated in response to DNA damage are numerous protein biosynthesis genes.

111 Following protein biosynthesis, glutamic acids on these proteins a

112 1, lamin B1, vimentin, and beta-actin) or in protein biosynthesis (glutamyl-prolyl-transfer RNA synth

113 ion in one or more of the steps that control protein biosynthesis has been associated with alteration

114 Equivalent inhibition of protein biosynthesis in a rabbit reticulocyte system and

115 nt increase in myocardial TNF-alpha mRNA and protein biosynthesis in adult cat hearts.

116 esis in the panicle of adult plants, whereas protein biosynthesis in adult leaves was 8-fold lower th

117 somes, the essential organelles required for protein biosynthesis in all cells, cause tissue-specific

118 Despite the broad requirement of GlyRS for protein biosynthesis in all cells, mutations in this gen

119 RNA (tRNA) molecules play a crucial role in protein biosynthesis in all organisms.

120 rotein molecules and plays a central role in protein biosynthesis in all organisms.

121 All of the products of mitochondrial protein biosynthesis in animals are hydrophobic proteins

122 cations for mRNA decay and the regulation of protein biosynthesis in bacteria.

123 expression elicits a sustained repression of protein biosynthesis in cells responding to stress.

124 e partitioning in support of storage oil and protein biosynthesis in developing COS.

125 cific RNA structures that regulate ribosomal protein biosynthesis in E. coli are narrowly distributed

126 r, these studies have shown that acute phase protein biosynthesis in enterocytes is regulated by infl

127 t protein complex required for initiation of protein biosynthesis in eukaryotic cells.

128 Inhibition was observed without effects on protein biosynthesis in general or PrP-sen biosynthesis

129 e study of interactions between DNA, RNA and protein biosynthesis in order to develop a more comprehe

130 e important to fine tune gene expression and protein biosynthesis in plant cells.

131 e important to fine-tune gene expression and protein biosynthesis in plant cells.

132 defense system in the plant kingdom, wherein protein biosynthesis in short, procumbent glandular tric

133 ependent increase in myocardial TNF mRNA and protein biosynthesis in the heart as well as in cultured

134 a brief HOCl exposure profoundly suppressed protein biosynthesis in the slices.

135 hanism mediated by ERs, and de novo mRNA and protein biosynthesis, in a sex- and region-dependent man

136 gth, taken as models for different stages of protein biosynthesis, in the absence and presence of the

137 air one or more steps of tRNA maturation and protein biosynthesis including 5'-end-processing, post-t

138 acterial metabolism as well as mitochondrial protein biosynthesis, induce neutrophil chemotaxis, the

139 In this study, we found that inhibition of protein biosynthesis induced phosphorylation/activation

140 recovery was observed in the presence of the protein biosynthesis inhibitor cycloheximide.

141 activates cell death only in the presence of protein biosynthesis inhibitors, which presumably block

142 Since ribosomally mediated protein biosynthesis is confined to the L-amino acid poo

143 Protein biosynthesis is inherently coupled to cotranslat

144 Furthermore, efficient inhibition of protein biosynthesis is observed.

145 vents, indicating that, while the process of protein biosynthesis is orthologous, its constituents ar

146 An indispensable step in protein biosynthesis is the 2(')(3(')) aminoacylation of

147 veals that RNA-based regulation of ribosomal protein biosynthesis is used in nearly all eubacterial p

148 (aa-tRNA) formation, an essential process in protein biosynthesis, is generally achieved by direct at

149 in a predicted C-terminal helical region for protein biosynthesis, localization, and interaction with

150 Tet(M) protein interacts with the protein biosynthesis machinery to render this process re

151 growth arrest, and suggest that restraining protein biosynthesis may be important in the prevention

152 Translation errors in protein biosynthesis may result in low level amino acid

153 of genes in pathways related to RNA, DNA and protein biosynthesis, metabolism and catabolism.

154 the operation of the SBP-single location Chl-protein biosynthesis model.

155 Whether a change in protein biosynthesis modulates protein degradation has n

156 ), matrix formation (n = 25), metabolism and protein biosynthesis (n = 27), cell signaling (n = 21),

157 anobacteria, plastids (chloroplasts) perform protein biosynthesis on bacterial-type 70S ribosomes.

158 Protein biosynthesis on the ribosome requires accurate r

159 Protein biosynthesis on the ribosome requires repeated c

160 oes not interfere with receptor binding or F protein biosynthesis or transport but prevents F protein

161 Protein biosynthesis, or translation, occurs on the ribo

162 d several molecular 'programs' implicated in protein biosynthesis, oxidative-stress responses and NF-

163 n mechanisms that exist at every step of the protein biosynthesis pathway, such as alternative splici

164 l understanding of lipid synthesis, membrane protein biosynthesis, phospholipid and membrane protein

165 cellular transport, phospholipid metabolism, protein biosynthesis, protein localization, protein meta

166 l lack an understanding of the dependence of protein biosynthesis rates on [ATP] and [GTP].

167 ree-dimensional mRNA structure and regulates protein biosynthesis rates raises the possibility that s

168 limits of our knowledge regarding ribosomal protein biosynthesis regulation outside of E. coli, and

169 Protein biosynthesis requires aminoacyl-transfer RNA (tR

170 Quality control of protein biosynthesis requires ER-retention and ER-associ

171 cell line up-regulated processes, including protein biosynthesis, responses to stress and responses

172 ing study, we show that H-MM is defined by a protein biosynthesis signature that is primarily driven

173 into two broad categories; those that affect protein biosynthesis/stability and traffic to the cell s

174 Salivary protein biosynthesis starts with the transcription and t

175 The alpha-helical motif was not required for protein biosynthesis, tetrameric subunit assembly, tetra

176 During protein biosynthesis the ribosome moves along mRNA in st

177 After each round of protein biosynthesis, the posttermination complex (PoTC)

178 is proteolytically processed by furin during protein biosynthesis, the S2' site is cleaved upon viral

179 During the elongation cycle of protein biosynthesis, the specific amino acid coded for

180 id residues are bound to the ribosome during protein biosynthesis, these small proteins do not fold u

181 erations of protein degradation may regulate protein biosynthesis through a feedback mechanism.

182 entails the manipulation of essential HIV-1 protein biosynthesis through unnatural amino acid (UAA*)

183 NX-3 inhibits protein biosynthesis to almost the same extent as the pr

184 egradation and calls for caution in blocking protein biosynthesis to study the half-life of proteins.

185 min superfamily, the SRP/SR family, and the "protein biosynthesis" translational GTPases.

186 Though protein biosynthesis, transport, and quality control in

187 e proteins for methoxymalonyl-S-acyl carrier protein biosynthesis (Ttm-ABCDE), eight proteins for dia

188 sduction, vesicular and molecular transport, protein biosynthesis, ubiquitination, and neuronal survi

189 mportant for bacterial growth and functional protein biosynthesis under certain conditions and is qui

190 s in ubiquitin-dependent protein catabolism, protein biosynthesis, vesicle trafficking and the respon

191 this transporter (and other factors) in heme protein biosynthesis, we developed plasmids that produce

192 To overcome this natural limitation on protein biosynthesis, we have evolved an orthogonal tRNA

193 r necrosis factor-alpha (TNF-alpha) mRNA and protein biosynthesis were examined in adult feline myoca

194 LIF mRNA and protein biosynthesis were examined in the adult feline h

195 r processes such as secondary metabolism and protein biosynthesis were generally not affected.

196 Moreover, TNF-alpha mRNA and protein biosynthesis were observed in myocyte and nonmyo

197 In addition, other proteins involved in protein biosynthesis were shown to be associated with ri

198 ould represent an early intermediate in MoFe protein biosynthesis where the P-cluster precursors have

199 gy is regulated by processes occurring after protein biosynthesis, which are critical for both channe

200 thionine by methionyl-tRNA synthetase during protein biosynthesis, which results in the formation of

201 metabolism accommodated different levels of protein biosynthesis while maintaining a consistent rate

202 HP 1 inhibited RNA and protein biosynthesis while not inhibiting DNA biosynthes

203 many studies have correlated deregulation of protein biosynthesis with cancer, it remains to be estab

204 r corroborated by showing that inhibition of protein biosynthesis with cycloheximide prior to 3-AP an