ライフサイエンスコーパス: protein carbonylation

1 adipose tissue lipid aldehyde production and protein carbonylation.

2 ity may be more influential on the extent of protein carbonylation.

3 naling complex attenuated ouabain-stimulated protein carbonylation.

4 sed susceptibility to mitochondrial membrane protein carbonylation.

5 of protein amino acids in a reaction termed protein carbonylation.

6 g promotes reactive oxygen species-dependent protein carbonylation.

7 , as well as its ability to suppress ROS and protein carbonylation.

8 dex of its activation), malonyl-CoA content, protein carbonylation (a marker of oxidative stress), pl

9 Protein carbonylation, a sensitive marker of hemoglobin

10 y TP than IP; this correlated with decreased protein carbonylation, a surrogate marker for oxidative

11 dine, and cysteine residues, referred to as "protein carbonylation." Although not widely appreciated,

12 Levels of protein carbonylation, amount of glutathione stores, and

13 ch cannot synthesize CL, exhibited increased protein carbonylation, an indicator of reactive oxygen s

14 ot by markers of proteostasis stress such as protein carbonylation and aggregation.

15 th models exhibited significant elevation in protein carbonylation and alterations in protein conform

16 ation rates, complex I protein and activity, protein carbonylation and ATP levels were all fully prot

17 ecies in plants, as evidenced from decreased protein carbonylation and hydrogen peroxide accumulation

18 o increased with OA treatment as measured by protein carbonylation and lipid peroxidation.

19 ense tryptophan and thiols depletion, higher protein carbonylation and more intense formation of prot

20 ations in p38K are associated with increased protein carbonylation and Nrf2-dependent transcription,

21 +0.05M glucose) for their ability to promote protein carbonylation and tryptophan depletion in myofib

22 function and exhibit decreased mitochondrial protein carbonylation and UCP2-dependent reduction in in

23 mitochondrial respiration, tissue nitration, protein carbonylation, and contractile function in the h

24 exhibit higher levels of lipid peroxidation, protein carbonylation, and DNA oxidative damage even at

25 NO synthase-2 expression, tissue nitration, protein carbonylation, and mitochondrial morphology and

26 tress signals related to lipid peroxidation, protein carbonylation, and nitration in WAT and liver.

27 the ROS-induced oxidative damage to DNA and protein carbonylation are involved in the observed toxic

28 Using protein carbonylation as a measure of oxidative stress,

29 We focused on protein carbonylation as an indicator of severe oxidativ

30 intracellular H(2)O(2) levels as measured by protein carbonylation assays and fluorescence-activated

31 ics), porphyrins, and lipid peroxidation and protein carbonylation blockers/inhibitors (edaravone and

32 nations of vemurafenib and UVA caused little protein carbonylation but were nevertheless inhibitory t

33 um levels of 8-oxo-dG-modified DNA and total protein carbonylation corresponded to cardioprotective a

34 iron, hallmarks of oxidative stress such as protein carbonylation, decreased aconitase activity, and

35 also exhibited severe lipid peroxidation and protein carbonylation, for oxidative stress damage at th

36 e the expression of GSTA4 and the role(s) of protein carbonylation in adipocyte function.

37 chemical dot blot method for quantitation of protein carbonylation in homogenates or purified protein

38 level of sensitivity allowed measurement of protein carbonylation in individual Drosophila.

39 scribe a novel DNPH-based method to quantify protein carbonylation in muscle and meat.

40 Protein carbonylation in response to ligand-receptor int

41 ygen species formation and a higher level of protein carbonylation in response to RSV infection.

42 A and FK506 pretreatments markedly increased protein carbonylation in the myocardium despite elevated

43 To address the role of protein carbonylation in the pathogenesis of mitochondri

44 Ethanol sensitivity and increased protein carbonylation in the taz1Delta mutant but not in

45 in cultured adipocytes resulted in increased protein carbonylation, increased mitochondrial ROS, dysf

46 During late stationary phase, mitochondrial protein carbonylation increases in all strains, particul

47 These results suggest that protein carbonylation is a post-translational modificati

48 Elevated protein carbonylation is accompanied by diminished compl

49 Ouabain-stimulated protein carbonylation is reversed after removal of ouaba

50 Protein carbonylation is the most commonly used measure

51 od, the new procedure reflected an increased protein carbonylation level measuring overall two to fou

52 Moreover, mitochondrial protein carbonylation levels in sod1, sod2, and sod1sod2

53 by measuring striatal aconitase activity and protein carbonylation levels.

54 c methods to identify the site and extent of protein carbonylation on a proteome-wide scale has expan

55 oxyguanosine (8-OH-dG) in DNA, and oxidative protein carbonylation) or to measure the expression of a

56 In both species, the dose-response for protein carbonylation parallels that for fecundity reduc

57 genistein, quercetin and gallic acid) on the protein carbonylation pathway occurred during the oxidat

58 These results suggest that protein carbonylation plays a major instigating role in

59 bain-stimulated Na/K-ATPase.c-Src signaling, protein carbonylation, redistribution of Na/K-ATPase and

60 f GSTA4 in adipose tissue leads to increased protein carbonylation, ROS production, and mitochondrial

61 Here we mapped protein carbonylation sites in raw milk and different br

62 eta vaga is far more resistant to IR-induced protein carbonylation than is the much more radiosensiti

63 Animal-source were more susceptible to protein carbonylation than soy proteins and globular wer

64 eroxides and suffer more DNA damage and more protein carbonylation than the parent.

65 hat the level of mitochondrial and cytosolic protein carbonylation, the level of 8-OH-dG in mitochond

66 These experiments identified protein carbonylation upon exposure of cells to sub-leth

67 Protein carbonylation was 65% higher in hearts of hypoxi

68 A 4-fold increase in protein carbonylation was measured within 15 min of init

69 Unexpectedly, the oxidative DNA damage and protein carbonylation was more severe in the DeltatrxC m

70 Protein carbonylation was significantly increased in T24

71 vels, mitochondrial density, ATP content and protein carbonylation were measured in cardiac muscle.

72 ivity, mass (i.e., cardiolipin content), and protein carbonylation, were assessed at various time poi

73 ts showed loss of CcO activity and increased protein carbonylation, which was accompanied by a declin

74 addition, atgrxcp lines displayed increased protein carbonylation within chloroplasts.