ライフサイエンスコーパス: protein microarray

1 nt with this compound by using reverse-phase protein microarray.

2 PR and MS detection on a single high-content protein microarray.

3 cinia virus, as determined by vaccinia virus protein microarray.

4 y, immunohistochemistry, DNA microarray, and protein microarray.

5 biota antigens was assessed by using a novel protein microarray.

6 n human sera on a genome level B. melitensis protein microarray.

7 to 5 avian influenza virus antigens, using a protein microarray.

8 targets were identified by immunoscreening a protein microarray.

9 ase were used to verify the formation of the protein microarray.

10 the majority of yeast protein kinases using protein microarrays.

11 dentification of nonspecific interactions on protein microarrays.

12 a with 8027 recombinant human proteins using protein microarrays.

13 ontrol of printed cDNA, oligonucleotide, and protein microarrays.

14 a combination of mass spectrometry (MS) and protein microarrays.

15 a from cancer cell lines using reverse-phase protein microarrays.

16 te the functionality of so-called functional protein microarrays.

17 cations and, in particular, for constructing protein microarrays.

18 ur the development of the next generation of protein microarrays.

19 t assays (ELISA), neutralization assays, and protein microarrays.

20 used recombinant Pak2 to screen high density protein microarrays.

21 d from joint immune complexes were tested on protein microarrays against a range of candidate autoant

22 and out as most promising for utilization in protein microarrays, albeit both have been used only spo

23 Protein microarray analyses revealed a number of protein

24 immunoglobulin reactivity data obtained from protein microarray analyses; and (ii) known protective a

25 A reverse-phase protein microarray analysis and Western blotting reveale

26 resented method is particularly relevant for protein microarray analysis because it is label-free, si

27 stem cells in breast tumors, we conducted a protein microarray analysis that identified the histone

28 e profile of the functions regulated by this protein, microarray analysis was used to examine transcr

29 We used a protein microarray and subsequent sequential enzyme-link

30 is of proteins in plants we have developed a protein microarray and used it to study the global analy

31 We have used protein microarrays and autoantibodies from cancer patie

32 al detection is well suited for high-content protein microarrays and comprehensive protein analysis-f

33 rved on the microarray was double-checked by protein microarrays and confirmed by aptamer-baited co-i

34 , thereby increasing the quality of spots in protein microarrays and especially improving screening t

35 gainst a panel of >8000 human antigens using protein microarrays and fluorescence detection.

36 roteomic and genomic levels with multiplexed protein microarrays and high-throughput DNA sequencing.

37 utilizes active mammalian cell extracts and protein microarrays and identified 1,500 potential subst

38 , flow cytometry based single-cell analysis, protein microarrays and interaction studies.

39 verexpressing STPB-C which were studied with protein microarrays and other techniques, direct examina

40 We used protein microarrays and quantitative fluorescence polari

41 A combination of protein microarrays and two-dimensional liquid-phase sep

42 the camels for IgG immunofluorescence assay, protein microarray, and virus neutralisation assay.

43 ion of protein expression by "reverse-phase" protein microarray; and (e) prospective validation of ca

44 parallel array of microfluidic channels for protein microarray applications.

45 The protein microarray approach revealed radiation-induced u

46 Protein microarrays are a powerful tool for ACAA detecti

47 iquid chromatography, mass spectrometry, and protein microarrays are among the proteomic tools availa

48 Multiplexed immunoassays on antibody-based protein microarrays are an attractive solution for analy

49 Protein microarrays are an emerging technology for study

50 Protein microarrays are fabricated from double-stranded

51 Here we demonstrate that functional protein microarrays are particularly well-suited for hig

52 Protein microarrays are the format of choice for high-th

53 The protein microarrays are useful for determining the compl

54 Protein microarrays are valuable tools for high-throughp

55 put project for identification of KSRs using protein microarrays, as well as known KSRs curated from

56 using a continuous titer measurement from a protein microarray assay.

57 Compared with protein microarrays assayed with the conventional incuba

58 Protein microarray assays revealed a burst of autoimmuni

59 ion in in situ signal amplification, DNA and protein microarray assays, single nucleotide polymorphis

60 NA interaction data for humans identified by protein microarray assays.

61 Protein microarray assessed the differential expression

62 , we efficiently fabricated both peptide and protein microarrays at relatively high density.

63 We probed the Arabidopsis protein microarray AtPMA-5000 with the N-terminal cytopl

64 We describe here 3-D protein microarrays based on nanopore alumina membranes

65 We developed a high-density self-assembling protein microarray, based on the nucleic acid programmab

66 integrating phosphoproteomic data with human protein microarray-based AKT1 kinase assays, we discover

67 Here, we describe a protein microarray-based approach to investigate determi

68 Here, we used a protein microarray-based approach to systematically surv

69 mputational prediction was validated using a protein microarray-based approach.

70 We benchmarked the protein microarray-based assay against a set of known qu

71 , we have used a combined bioinformatics and protein microarray-based strategy to systematically char

72 vant expression vector and used to produce a protein microarray by transcribing, translating, and cap

73 We generated protein microarrays by printing complementary DNAs onto

74 ave demonstrated proof of the concept that a protein microarray can type whole blood and detect antib

75 esign approaches, the overall performance of protein microarrays can be compromised by diffusion-limi

76 We show that protein microarrays can serve as a rapid, sensitive, and

77 Protein microarray chips are probed with sera from indiv

78 Reverse-phase protein microarrays combined with Western blotting revea

79 A B. melitensis protein microarray comprised of nearly all proteins enco

80 Here we use protein microarrays comprising virtually every Src homol

81 orophore-conjugated antibody and tested on a protein microarray configuration with good sensitivity a

82 ELISA assays and protein microarrays constructed with double-His6 GFP dem

83 vide insight into this area, we fabricated a protein microarray containing 1,205 Burkholderia pseudom

84 Here we used a protein microarray containing 2,724 Salmonella enterica

85 Using the DUB Chip, a protein microarray containing 35 DUBs, we demonstrate a

86 To this end, we developed a protein microarray containing approximately 23% of the P

87 We probed protein microarrays covering 824 unique P. falciparum pr

88 An important application of protein microarray data analysis is identifying a serodi

89 array, the majority of the valuable original protein microarray data is still not publically accessib

90 d on an external pathogen proteome for which protein microarray data were obtained after the initial

91 in a comprehensive analysis report for their protein microarray data.

92 s very well when tested against experimental protein microarray data.

93 fically designed for archiving and analyzing protein microarray data.

94 To address this issue, we constructed Protein Microarray Database (PMD), which is specifically

95 tective antigens when trained using only the protein microarray datasets.

96 Protein microarray demonstrated that inhibition of media

97 f human serum from 166 individuals via human protein microarrays demonstrates that IgG autoantibodies

98 Protein microarray development is absolutely dependent u

99 ion and dehydration problems associated with protein microarray development.

100 Besides to protein microarrays, DNA microarrays were also developed

101 h as kinase assays using modified kinases or protein microarrays, enables rapid kinase substrate iden

102 Protein microarray experiments revealed that more than 1

103 Protein microarrays exposed to cellular extracts could o

104 ods to assess the quality and performance of protein microarrays fabricated from undefined protein co

105 The approach uses high-density protein microarrays fabricated using nucleic acid progra

106 The most challenging step in protein microarray fabrication is high-throughput produc

107 This convenient on-chip protein microarray fabrication method can be implemented

108 Our results showed that serum factor protein microarrays facilitate detection of autoantibody

109 oactivators in solution FRET experiments and protein microarray fluorometric and FRET assays.

110 unbiased manner, we constructed a multiplex protein microarray for detection of serum factor-binding

111 mpact PEL cell survival, we screened a human protein microarray for ERK-primed GSK-3 substrates.

112 A protein microarray for the early stage diagnosis of seps

113 assessed the sensitivity and specificity of protein microarrays for ACAA identification and discover

114 We employ plasmonic protein microarrays for the early detection of a cancer

115 uses for our approach: as an alternative to protein microarrays for the identification of drug targe

116 ly relevant concentrations of TNF-alpha in a protein microarray format that can be expanded to multip

117 tection of a panel of cancer biomarkers in a protein microarray format.

118 As an example, we interrogated a protein microarray formed by a commercial drop-on-demand

119 The current technology for protein microarrays has been derived primarily from DNA

120 The development of peptide and protein microarrays has created enormous opportunities i

121 In the short term, protein microarrays have a greater potential to impact d

122 DNA and protein microarrays have become an established leading-e

123 Protein microarrays have demonstrated to be cost-effecti

124 Protein microarrays have emerged as an indispensable res

125 vents, measured by time-series reverse-phase protein microarrays, high-content imaging, and flow cyto

126 we evaluated responses to 856 Pf antigens by protein microarray in 186 Ugandan children, for whom det

127 and approximately 5,000 human proteins using protein microarrays in an attempt to better understand t

128 nized 1547 proteins present on a large-scale protein microarray, indicating polyreactivity.

129 Protein microarray is a powerful technology for both bas

130 Furthermore, a survey of recent protein microarray literature reveals that an even wider

131 Using a protein microarray made up of 1920 elements (146 distinc

132 Protein microarrays may be useful in the search for mala

133 al genomic data while new data types include protein microarray, metabolic pathways, compounds, quant

134 ed imaging reflectometry (AIR), a label-free protein microarray method.

135 ed P. aeruginosa PAO1 proteins by a modified protein microarray methodology called the nucleic acid-p

136 exchange averaged nearly 70%, quantified by protein microarray of individual trabeculae.

137 We have produced protein microarrays of a near-complete vaccinia proteome

138 PA can analyze hundreds (even thousands on a protein microarray) of proteins in a single experiment,

139 Protein microarrays offer a high-throughput method for d

140 Here we present protein microarrays on a novel nanostructured, plasmonic

141 tforms (planar and bead array, reverse phase protein microarray, phosphoflow, AQUA and mass spectrome

142 We developed a new protein microarray platform that utilizes a filtration a

143 za viruses in the general population using a protein microarray platform.

144 Protein microarrays presenting spots of collagen and lip

145 atform that utilizes a filtration assay with protein microarrays printed on protein-permeable nitroce

146 Protein microarray profiling identified the adaptor TAB1

147 eins for ovarian cancer and demonstrate that protein microarrays provide a powerful approach to ident

148 Protein microarrays provide a powerful tool for the stud

149 Protein microarrays provide an efficient way to identify

150 Protein microarrays represent an emerging technology tha

151 We used a protein microarray representing 491 P. falciparum protei

152 Protein microarray results were validated by using an in

153 assays using recombinant Erk3 confirmed the protein microarray results, and phospho-specific antiser

154 A bead-based assay was used to validate protein microarray results.

155 atients using native protein and recombinant protein microarrays revealed unique disease-specific, hu

156 igh-throughput screening approach based on a protein microarray reveals that many human transcription

157 We tested this hypothesis with reverse-phase protein microarrays (RPA) for multiplexed cell signaling

158 Using reverse-phase protein microarrays (RPMAs), we evaluated the activation

159 Reverse-phase protein microarrays (RPPAs) are a useful platform for id

160 nd hippocampus was measured by reverse phase protein microarray (RPPM).

161 A human protein microarray screen identified direct SNORD50A and

162 In this work we used a protein microarray screen to identify the Rac-specific G

163 Starting from an unbiased protein microarray screen, we identified a set of lipopr

164 Protein microarray secretome analyses revealed angiogeni

165 ughput and multiplexing of T cell detection, protein microarrays spotted with defined p/MHC complexes

166 ectroscopy kinetic and equilibrium analyses, protein microarray studies, and I-TASSER structural mode

167 ne the most important tenets of a functional protein microarray such as covalent attachment, native p

168 A protein microarray system containing different dilutions

169 Through the use of a chimaeric protein microarray system together with sera from a pane

170 nature of systemic adverse events, we used a protein microarray technique to precisely quantitate 108

171 gnals from a newly developed high-throughput protein microarray technique.

172 ging as specific protein capture reagents in protein microarray technologies.

173 rks, we used reverse-phase signaling pathway protein microarray technology and identified three signa

174 study were to (i) establish high-throughput protein microarray technology as a method to investigate

175 Finally, recent developments in protein microarray technology provide a versatile tool t

176 cial flat panel OLED display technology with protein microarray technology to enable high-density flu

177 Our results demonstrate that protein microarray technology, combined with the target

178 substrates targeted by protein kinases using protein microarray technology.

179 ia patients and 40 healthy individuals using protein microarray technology.

180 acellular interaction screen) assay by using protein microarray technology.

181 ult is the on-chip, cell-free synthesis of a protein microarray that can be used immediately for SPRI

182 ory syndrome (SARS) infection, a coronavirus protein microarray that harbors proteins from SARS coron

183 ternative substrate for printing multiplexed protein microarrays that have greater sensitivity throug

184 ere is no database specifically tailored for protein microarray, the majority of the valuable origina

185 t injury are poorly characterized, we used a protein microarray to compare antibody repertoires in pr

186 We also used a protein microarray to demonstrate a postgenomic applicat

187 e JCI, Price and colleagues used a multiplex protein microarray to identify autoantibodies in serum f

188 We used a human protein microarray to identify the actin-regulatory prot

189 We investigated the potential of this protein microarray to screen for interactions between le

190 in chip ubiquitination screen using a human protein microarray to uncover putative substrates for th

191 e-cancer tissue, we developed and used phage protein microarrays to analyze serum samples from 119 pa

192 Here, we use protein microarrays to assess binding to >9,400 human pr

193 lobulinemia (WM), we employed antibody-based protein microarrays to compare patterns of protein expre

194 sed the activated MPKs to probe high-density protein microarrays to determine their phosphorylation t

195 of these changes in enzyme activity, we used protein microarrays to identify cell proteins that were

196 The use of protein microarrays to profile the autoAb response in PV

197 Using high-density protein microarrays to screen post-HSCT plasma, we ident

198 We used protein microarrays to serologically identify nucleolar

199 ause of the increasing use of biosensors and protein microarrays, two technologies that use protein i

200 ch the entire database by experimental name, protein microarray type, and sample information.

201 a biosensing unit, such as AMS, MALDI-MS or protein microarray-type biochips.

202 Our results further demonstrate that protein microarrays uncover a diverse set of interaction

203 nd were suitable for the printing of ordered protein microarrays used in protein-protein interaction

204 l be useful for a wide variety of functional protein microarray users.

205 Optimal conditions for depositing protein microarrays using a continuous-flow microfluidic

206 The analysis of self-assembled protein microarrays, using matrix-assisted laser desorpt

207 Reactivity to 21 PfEMP1 fragments on a protein microarray was measured in serum samples from Ma

208 An Epstein-Barr virus (EBV) protein microarray was used to screen for proteins bindi

209 Using this novel protein microarray we have longitudinally analysed the s

210 Using reverse-phase protein microarrays, we identified a breast tumor protei

211 2 (FLS2) receptor using Arabidopsis thaliana protein microarrays, we identified the reticulon-like pr

212 Using these 65 antigens on protein microarrays, we trained neural networks on two-c

213 tive bioinformatics and Mycobacterium leprae protein microarrays were applied to investigate whether

214 linical applications of the filtration-based protein microarrays were demonstrated by detecting carci

215 Three applications for protein microarrays were demonstrated: screening for pro

216 Highly multiplexed protein microarrays were designed and fabricated.

217 Protein microarrays were exposed to these complex extrac

218 Protein microarrays were highly sensitive and specific f

219 Protein microarrays were prepared and screened with seve

220 Protein microarrays were printed onto poly(ethylene glyc

221 Protein microarrays were used to characterize designed,

222 Protein microarrays were used to measure levels of anti-

223 To identify these pathways, protein microarrays were used to profile the phosphoryla

224 The array is then used to print a protein microarray, where each element contains the anti

225 identify methylated residues, as well as to protein microarrays, where they can be used to screen fo

226 method for identifying new substrates using protein microarrays, which can markedly expand the list

227 n, the combination of chimaeric proteins and protein microarrays will greatly facilitate the screenin

228 ptors against a highly diverse extracellular protein microarray with 686 genes represented.

229 vities targeted by SA, we probed Arabidopsis protein microarrays with a functional analog of SA.

230 demonstrate a method to create high density protein microarrays with excellent spot uniformity using

231 on the PEG net-cloth enables the creation of protein microarrays with high signal to noise ratio.

232 By probing high-density protein microarrays with patient plasma, we discovered 3

233 study of small molecule binding kinetics on protein microarrays with plasmonic-based electrochemical

234 By combining the throughput of protein microarrays with the fidelity of fluorescence po

235 Fully functional protein microarrays, with monolayer arrangements and com