ライフサイエンスコーパス: protein motif

1 ed amino acids within the aldose 1-epimerase protein motif.

2 nction of both proteins and may define a new protein motif.

3 nsitive and assigned to a penicillin-binding protein motif.

4 tanding of the major forces maintaining this protein motif.

5 ts that this PxxP segment can bind to an SH3 protein motif.

6 mino-acid units that lacks homology to known protein motifs.

7 f (RRM) is one of the most common eukaryotic protein motifs.

8 he two sequences and patterns of DNA-binding protein motifs.

9 ctions correspond to junctions of individual protein motifs.

10 structures, phylogenetic relationships, and protein motifs.

11 es previously unrecognized rearrangements of protein motifs.

12 n in AHI1 is found in a region with no known protein motifs.

13 n an automatic mode aimed at discovering new protein motifs.

14 ed or decreased frequencies of particular SR protein motifs.

15 de sequence known as a PIP (PCNA interacting protein) motif.

16 deletion proteins, we now show that the Jak2 protein motif (231)YRFRR is required for the co-associat

17 Addition of the C2 protein motif (a structural domain found in proteins imp

18 encodes a polypeptide with two recognizable protein motifs: a RING domain near the N terminus and tw

19 on kinetics and RNA release suggest that the protein motifs affected by them have multiple roles in t

20 Specific protein motifs also point to a degree of homology with m

21 Transcriptome and protein motif analyses showed that approximately one-hal

22 Gene expression, protein motif and intron number were examined.

23 a robust multidomain scaffold with different protein motifs and activities contributing differentiall

24 ed in regulatory regions associated with MYC protein motifs and affect gene expression.

25 he course of this analysis, highly conserved protein motifs and domains within each of the AARS loci

26 We also applied RABIT on RNA-binding protein motifs and found that some alternative splicing

27 t signatures in 3'UTR variation, RNA-binding protein motifs and miRNA expression associated with tran

28 loss by testing the importance of different protein motifs and partners in the developing CNS, where

29 D At A also contains protein motifs and protein similarities derived from sea

30 ins, transforming growth factor-beta binding protein motifs, and two RGD binding sites.

31 paradigms attribute functions to particular proteins, motifs, and amino acids.

32 ated from the order in which the conserved G protein motifs appear in the sequence, the GTPase domain

33 These protein motifs appeared to be the regions where TnI-TnT

34 These protein motifs are derived from 7697 sequence alignments

35 A number of helix-rich protein motifs are involved in a variety of critical pro

36 Several proteins and protein motifs are known to be required for PtdSer trans

37 These protein motifs are suggested to mediate protein-protein

38 a database of protein families and conserved protein motifs) as well as manually adjusted multiple al

39 nosoma cruzi and Leishmania major identified protein motifs associated with catalysis and protein or

40 d amino acid compositions and for particular protein motifs associated with known HRGPs.

41 lity with the design target, a betabetaalpha protein motif based on the polypeptide backbone structur

42 analysis helps to clarify how non-symmetric protein motifs bind to the double helix of DNA through t

43 ein, termed BCL7A, exhibited no recognizable protein motifs but showed homology with the actin-bindin

44 A protein motif called a PDZ domain is important in the ta

45 rates by interacting with a conserved target protein motif called the destruction box.

46 NC domain which closely resembles a cellular protein motif called the F-box domain.

47 of zinc finger proteins containing a unique protein motif called the positive regulatory (PR) domain

48 orithm is generally applicable to any DNA or protein motifs, can produce highly stable and biological

49 The FYVE domain is a conserved protein motif characterized by its ability to bind with

50 main is a largely uncharacterized tripartite protein motif conserved among eukaryotic proteins.

51 ns one double-stranded RNA-binding domain, a protein motif conserved among many double-stranded RNA-b

52 We identified a novel basic protein motif consisting of a cluster of three dibasic r

53 riants will help us determine which inversin protein motifs contribute to left-right asymmetry and ki

54 pears that the AT-hook motif is an auxiliary protein motif cooperating with other DNA-binding activit

55 side this conserved domain and no identified protein motifs could be deduced.

56 conserved domain database (CDD) and PROSITE protein-motif database improves COBALT's alignment quali

57 e basic region-leucine zipper (B-ZIP) (bZIP) protein motif dimerizes to bind specific DNA sequences.

58 NestedMICA, an open source protein motif discovery tool written in Java, is driven

59 As an archetype for protein motif-driven regulation of cell function, the AP

60 The Slp1 protein contains a protein motif (EH1) which mediates binding to the transc

61 These basic protein motifs exhibit weak but physiologically relevant

62 tself to be a robust and sensitive ab initio protein motif finder, even for relatively short motifs t

63 ompared its performance with another popular protein motif finder, MEME.

64 In order to assess NestedMICA as a protein motif finder, we have tested it on synthetic dat

65 PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL compos

66 Unlike ZFNs and TALENs that use protein motifs for DNA sequence recognition, CRISPR-Cas9

67 inger domain is a novel zinc-binding Cys-His protein motif found in a growing number of proteins invo

68 The dsRBM is a conserved protein motif found in many proteins from most organisms

69 ely 100 amino acid residues are a functional protein motif found in many signal-transducing and cytos

70 FF domains are poorly understood protein motifs found in all eukaryotes but in a very sma

71 dly, this work elucidates the role of common protein motifs found in carbohydrate-active enzymes that

72 oth deduced proteins contain three conserved protein motifs found in the active site of all eubacteri

73 physiologically relevant occurrences of any protein motif identified in a eukaryotic proteome.

74 ces encoding the sterol-sensing domain (SSD) protein motif identified two sets of DNA sequences with

75 acids that couple RNA and ATP binding to the protein (Motif III).

76 0 amino acids consisting of three functional protein motifs implicated in vesicle transport and prote

77 y MHC molecules during natural processing of proteins, motifs important for selection of processed pe

78 The C2H2 zinc finger is the most prevalent protein motif in the mammalian proteome.

79 gen triple helix is one of the most abundant protein motifs in animals.

80 Amongst the most common protein motifs in eukaryotes are zinc fingers (ZFs), whi

81 ene coregulated by 16E6 and NFX1-123 and the protein motifs in NFX1-123 that are important for this e

82 y has revealed the presence of two conserved protein motifs in the middle of the lumenal catalytic do

83 organization of exons which encode specific protein motifs in the mOST-PTP molecule.

84 We have examined conserved protein motifs in the non-coding, intergenic regions ("p

85 MRG15 contains several predicted protein motifs, including a nuclear localization signal,

86 Exon skips cause loss of inversin protein motifs, including ankyrin repeats, IQ domains, d

87 rch against the BLOCKS database of conserved protein motifs indicates that Psdr1 retains features ess

88 Moreover, a small protein motif interacts with five of these determinants,

89 the N-terminus of nNOS, which contains a PDZ protein motif, interacts with similar motifs in postsyna

90 complex contain tetratricopeptide repeats, a protein motif involved in protein/protein interactions.

91 The function of this protein motif is dependent on stretches of rare codons,

92 that the Poleta C-terminal PCNA-interacting protein motif is required for the exchange process.

93 The versatile coiled-coil protein motif is widely used to induce and control macro

94 tructure can be recognized by many different protein motifs, it is not surprising that apparently unr

95 novel combination of a paired domain-related protein motif juxtaposed to a leucine zipper-like domain

96 -V-V) conforms to a sequence that binds to a protein motif known as the PDZ domain.

97 on the largest family of HEGs (encoding the protein motif, LAGLIDADG) to understand how HEGs and int

98 rwise highly conserved intermediate filament protein motif LNDR.

99 A protein motif located at the border of the SMAD-binding

100 Thus, this shared protein motif may play an analogous role in mediating th

101 We describe the use of Pfam protein motif models and the HMMER program to predict wh

102 MotifProp is based on a protein-motif network, in which edges connect proteins a

103 Despite the complex structure of the protein-motif network, MotifProp can be easily interpret

104 fied recombinant mosaic AGPases derived from protein motifs normally expressed in the maize (Zea mays

105 n a genetic pathway, and san and vtn contain protein motifs, NPxY and PTB domain, respectively, known

106 CT domain (for BRCA1 carboxyl terminus) is a protein motif of unknown function, comprising approximat

107 WW domains are conserved protein motifs of 38-40 amino acids found in a broad spe

108 uman sequences reveals that the recognizable protein motifs of BARD1 are well conserved, including th

109 adenovirus E4 ORF1 proteins lacked conserved protein motifs of dUTPase enzymes or detectable enzymati

110 tagenesis studies, we further identified the protein motifs on TOB and PABPC1 that are necessary for

111 rine, and 6% methionine, but no recognizable protein motifs or significant homologies to any other kn

112 (formerly thought exclusively nuclear); this protein motif organization is unprecedented.

113 The F-box represents a protein motif originally identified as a conserved amino

114 terminal domain binds lipids through a novel protein motif, permitting complexin to inhibit spontaneo

115 oliferating-cell-nuclear-antigen-interacting protein motif (PIP-box) and the KEN-box (recognized by t

116 erminal domain, individual cullins bind to a protein motif present in multiple proteins to recruit sp

117 as found to be induced by the leucine zipper protein motif, rather than structural distortions of DNA

118 emerging family of proteins sharing a set of protein motifs referred to as PET-LIM domains.

119 Protein motifs represent highly conserved regions within

120 cterized Rbf1 turnover in Drosophila and the protein motifs required for its destabilization.

121 A search for functionally significant protein motifs revealed consensus sequences for N-glycos

122 ligand domain involving both sialic acid and protein motif(s).

123 We have combined protein motif search and gene finding methods to identif

124 ncy similarity search by using BLASTN, and a protein motif search of the human ORFeome by using hidde

125 bidopsis genomic sequences and new Blast and protein motif search results.

126 ents of inferred protein sequences, DNA, and protein motif searches and protein secondary structure p

127 searches of pre-computed BLAST results, and protein motif searches.

128 was identified with a potential RNA binding protein motif similar to sex lethal that appears to have

129 most of the short (3-9 amino acid long) test protein motifs spiked into a test set of sequences at di

130 dered a likely candidate on the basis of its protein motif structure and expressed-sequence-tag repre

131 Analysis of protein motif structure of the Dof paralogs and their an

132 c domains of Ets proteins interact with many protein motifs such as bHLH, bZipper and Paired domain.

133 hlights the flexibility of core cytoskeletal protein motifs, such that one type of cytoskeletal eleme

134 ar expression of Ma proteins and analysis of protein motifs suggest that these proteins play roles in

135 to protease trafficking and suggests that a protein motif targeting signal for lysosomal proteases a

136 We identified a novel conserved protein motif, termed the "leucine latch," at the N term

137 trate the use of Suns to interactively build protein motifs, tertiary interactions, and to identify s

138 oreover, the widely utilized TIR domain is a protein motif that can possess enzymatic activity.

139 The PR domain is a newly recognized protein motif that characterizes a subfamily of Kruppel-

140 These findings define a novel protein motif that functions in intracellular calcium si

141 be explained by their possession of a common protein motif that interacts with a binding site on prot

142 ins the nuclear matrix targeting signal, the protein motif that is necessary and sufficient to target

143 stablish the nucleosomal binding domain as a protein motif that is present in other than just the ubi

144 genetic approach, we have uncovered a novel protein motif that limits the transcriptional synergy of

145 sequence, creating a regulatable RNA-binding protein motif that retains its functional activity.

146 Motif III is one of the seven protein motifs that are characteristic of superfamily I

147 The active site is composed of six protein motifs that are conserved in order and spacing a

148 their PDX1 counterparts but contain several protein motifs that are conserved throughout all PDX2 pr

149 dent eEF1A mutations localize close to the G-protein motifs that are crucial for nucleotide binding.

150 e and other ABC transporters reveals several protein motifs that are highly conserved both in sequenc

151 e (EGF) repeats are also small cysteine-rich protein motifs that can be O-glycosylated by several ER-

152 that Notch-like EGF and discoidin/C domains, protein motifs that facilitate a variety of cellular int

153 We identified a protein motif, the DWD box (DDB1-binding WD40 protein),

154 Here, we describe a protein motif, the GTB motif (for G1/S transcription fac

155 es respect neither functional nor structural protein motifs, the introns appear to be relatively rece

156 mino acid propensities for another important protein motif: the collagen triple-helix conformation wi

157 f mediating specific pairing of a widespread protein motif: the parallel, dimeric, alpha-helical coil

158 We analyze a variety of repeating protein motifs, TIM barrels, propellor blades, coiled co

159 yrosine-rich protein (FYRP), both containing protein motifs typically found on chromatin proteins.

160 Drosophila Ftz proteins with mutated protein motifs were expressed under the control of a neu

161 Models for three cadherin protein motifs were generated from over 100 already anno

162 Three conserved protein motifs were identified by aligning the VP3 and V

163 The AT-hook is a small DNA-binding protein motif which was first described in the high mobi

164 the evolutionary origins of this ubiquitous protein motif, which is found soluble exclusively as an

165 Cpk proteins do not contain any recognizable protein motif, while the C termini contain "C2 domains,"

166 cible domain, a small, genetically encodable protein motif whose structure is dependent on its tyrosi

167 Protein motifs with established functions found in CRTs

168 maize NBS1 orthologues that share conserved protein motifs with human NBS1.

169 Previous work demonstrated a beta-hairpin protein motif within this region to be responsible for D